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1. Systematic Review of Participant Sex, Race and Ethnicity Reporting in Interstitial Lung Disease Clinical Trials.
作者: Jackie Lin.;Genevieve Gillett.;Martin Ieong.;Benjamin Aronson.;Dylan Douglas.;Timothy Dyster.;Suresh Garudadri.;Layne Keating.;Ayodeji Adegunsoye.;Erica Farrand.
来源: Chest. 2026年
Improving the generalizability of interstitial lung disease (ILD) research requires inclusion of diverse populations in clinical trials. Despite ongoing efforts to improve racial and ethnic minority participation, reporting and representation of sex, race, and ethnicity in ILD studies remain sub-optimally defined. This systematic review evaluated demographic reporting and participant representation in recent ILD clinical trials.
2. Effects of a sea level stay on pulmonary hemodynamics in patients with pulmonary arterial hypertension living in Quito near 2850m.
作者: Silvia Ulrich.;Julian Müller.;Michael Furian.;Stéphanie Saxer.;Simon R Schneider.;Joel Herzig.;Meret Bauer.;Mirjam Schmucki.;Diego Saragoni.;Laura Mayer.;Esther I Schwarz.;Elizabeth Cajamarca.;Rodrigo Hoyos.;Mona Lichtblau.
来源: Chest. 2026年
Amongst the >80 Mio people living >2500m are patients with pulmonary arterial hypertension (PAH).
3. Early Trends After Safety Net Policy Introduction for Kidney After Lung Transplantation.
作者: Prasanth Balasubramanian.;Napat Leeaphorn.;Kristopher P Croome.;Pablo Moreno Franco.;Aditya Khanijo.;Remzi Bag.;Maher A Baz.;Narula Tathagat.;Alvarez G Francisco.;Dana K Perry.;C Burcin Taner.;Hani M Wadei.;Tambi Jarmi.;Devang Sanghavi.;Mathew Thomas.;Ian A Makey.;John Haney.;Sadia Z Shah.
来源: Chest. 2026年
The safety-net policy for kidney-after-lung transplants (KALT), implemented in the U.S. on 6/29/2023, allows Lung Transplant (LT) candidates with acute kidney injury (AKI), with or without underlying chronic kidney disease (CKD), to undergo LT alone with the potential for renal recovery. This may decrease the need to list for simultaneous lung-kidney transplant (SLKT).
4. The impact of disease severity and symptoms on anxiety and depression in individuals with idiopathic pulmonary fibrosis.
作者: Zhe Wu.;Karen Moor.;Marlies Wijsenbeek.;Christina Schlecker.;Gerrit Weimann.;Toby M Maher.;Philip L Molyneaux.
来源: Chest. 2026年
Idiopathic pulmonary fibrosis (IPF) is a debilitating, life-limiting fibrotic lung disease. Symptoms including breathlessness, cough, and fatigue, together with disease severity, contribute to psychological burden, yet the relationship between these factors and anxiety and depression remains unclear.
6. Suggested novel risk factors for Swimming-Induced Pulmonary Edema - asthma and limited open water swimming experience.
作者: Linda Kristiansson.;Claudia Seiler.;Annika Braman Eriksson.;Josefin Sundh.;Maria Hårdstedt.
来源: Chest. 2026年
Swimming-induced pulmonary edema (SIPE) has gained increasing attention in recent years. However, risk factors for SIPE remain incompletely understood, and existing data are primarily based on small-scale studies.
8. Secular Trends in Acute Respiratory Distress Syndrome: A 20-Year Analysis of the National Inpatient Sample.
作者: Prathap Padappayil.;Dishant Shah.;Timothy Jackson.;Mary E Helander.;Viren Kaul.;Auyon J Ghosh.
来源: Chest. 2026年
Mortality from acute respiratory distress syndrome (ARDS) remains high, but large-scale longitudinal analyses in the pre-COVID era are limited.
9. A Randomized, Placebo-Controlled, Double-Blind, Crossover Trial of Inhaled Nitric Oxide in Patients With Mild-to-Severe COPD.
作者: Sophie É Collins.;Miranda Kirby.;Benjamin M Smith.;Zahrah H Rampuri.;Desi P Fuhr.;Samira Rowland.;Andrew R Brotto.;Rhonda J Rosychuk.;Stephanie Thompson.;Jason Weatherald.;Sean van Diepen.;Michael K Stickland.; .
来源: Chest. 2026年
Patients with advanced COPD have pulmonary vascular dysfunction and destruction; thus, it is unclear whether they are responsive to selective pulmonary vasodilators.
10. Efficacy and safety of Landiolol in cardiogenic shock patients.
作者: Giovanni Tavecchia.;Guido Tavazzi.;Giovanna Viola.;Andrea Cesari.;Carlos L Alviar.;Daniele Cucchi.;Costanza Natalia Julia Colombo.;Luca Villanova.;Alessandro Fasolino.;Rita Camporotondo.;Fabrizio Oliva.;Alice Sacco.
来源: Chest. 2026年 11. Efficacy and Safety of Ensifentrine in Chinese Patients with Chronic Obstructive Pulmonary Disease: The ENHANCE-CHINA Randomized Clinical Trial.
作者: Yumin Zhou.;Charlie Chen.;Zihui Wang.;Fan Wu.;Dongbo Tian.;Zuke Xiao.;Jie Cao.;Feng Xu.;Junzhen Gao.;Juan Chen.;Liping Peng.;Yuanrong Dai.;Limin Dong.;Yi Hu.;Ting Yang.;Chuntao Liu.;Limin Wang.;Xiao Liu.;Tiebo Yang.;Guoru Yang.;Dan Zhu.;Zonghui Wei.;Wei Gu.;Pixin Ran.;Nanshan Zhong.; .
来源: Chest. 2026年
Ensifentrine, a novel phosphodiesterase 3/4 inhibitor, significantly improved lung function and reduced chronic obstructive pulmonary disease (COPD) exacerbations in previous trials in Western populations. However, efficacy and safety data on its use in participants with COPD in China remain limited.
12. Cone Beam Computed Tomography-Guided Bronchoscopy versus Computed Tomography-Guided Transthoracic Needle Biopsy for Peripheral Pulmonary Lesion Diagnosis.
作者: Pranjal Patel.;David E Ost.;Brian Shaller.;Jiwoon Chang.;Aishwarya Yenepalli.;Hee Jae Choi.;Dwayne Free.;Cyra-Yoonsun Kang.;Eric Sumner.;Carrie Cao.;Harmeet Bedi.
来源: Chest. 2026年
The identification of peripheral pulmonary lesions (PPLs) has increased significantly, either incidentally or through lung cancer screening, necessitating more biopsies to differentiate between malignant and benign etiologies. Cone beam computed tomography-guided bronchoscopic biopsy (CBCT-GB) and computed tomography-guided transthoracic needle biopsy (CT-TTNB) are commonly used for these biopsies, but their comparative diagnostic abilities have not been studied.
14. Clinical profiles and lung function trajectories of IIM-ILD patients: A comparative study of pulmonology and rheumatology settings.
作者: Rachele Vallara.;Helena Andersson.;Ilaria Bassi.;Cathrine Brunborg.;Gilda Giancotti.;Phuong Phuong Diep.;Aldo Guerrieri.;Håvard Fretheim.;Stefano Nava.;Torhild Garen.;Venerino Poletti.;Hilde Jenssen Bjørkekjær.;Lara Pisani.;Emily Langballe.;Sara Piciucchi.;Marthe Mæhlen.;Claudia Ravaglia.;Natasha Moe.;Maurizio Zompatori.;Øyvind Molberg.;Janne Walle.;Anna-Maria Hoffmann-Vold.
来源: Chest. 2026年
Idiopathic inflammatory myopathies (IIM) are frequently complicated by interstitial lung disease (ILD). Although clinical heterogeneity is recognized, comparisons between IIM-ILD patients managed in pulmonology- versus rheumatology centers remain limited.
15. The Economic Consequence of Increased Healthcare Resource Utilization in Maryland Associated with a Major Wildfire Smoke Event.
作者: Zafar Zafari.;Mary E Maldarelli.;Clayton H Brown.;Madhurika Situt.;Colleen Reilly.;Rozalina McCoy.;Martha Jurczak.;Amir Sapkota.;Katarina Zeder.;Warren D'Souza.;Bradley A Maron.
来源: Chest. 2026年
Transcontinental wildfire smoke migration originating from remote areas resulted in consecutive days of high concentrations of particulate matter (PM2.5) in Maryland in June 2023.
16. The Canadian Thoracic Society/Canadian Sleep Society Guideline on the diagnosis of obstructive sleep apnea in children.
作者: Joanna E MacLean.;Adetayo Adeleye.;Anne Van Dam.;Avtar Lal.;Tamer Abusido.;Darryl J Adamko.;Reshma Amin.;Paolo Campisi.;Evelyn Constantin.;Julie Duncan.;Gordon Dyck.;Jodi Jones.;Ajay Kevat.;James Lee.;Jenny Shi.;Mitchell Zelman.; .
来源: Chest. 2026年
Access to polysomnography, the recommended standard for the diagnosis of obstructive sleep apnea (OSA) in children, is limited in many jurisdictions. Many children undergo treatment for OSA without confirmatory testing, are denied treatment in the absence of testing, or have a delay in treatment of other sleep disorders until OSA can be ruled out.
17. The 2021 US Preventive Services Task Force Lung Cancer Screening Criteria Miss Many Patients Diagnosed with Early- and Late-Stage Lung Cancer: Analysis of Three Cohort Studies.
作者: Alexandra L Potter.;Quiana Guo.;Bryan Rettner.;Alexander Zhu.;Ava Potter.;Wei Zheng.;Jui Kothari.;Andrea Shafer.;Linda W Martin.;Mary M Pasquinelli.;David C Christiani.;Chi-Fu Jeffrey Yang.
来源: Chest. 2026年
Lung cancer screening (LCS) aims to detect lung cancers-that have historically been diagnosed at late stages-at earlier stages when the likelihood of cure is high. However, the proportion of individuals diagnosed with late-stage lung cancer in the U.S. who would have qualified for LCS is unknown.
18. Assessment of Abdominal Adiposity in Obstructive Sleep Apnea using PET/MRI: Impact of Short-Term CPAP.
作者: Jennifer Prevot.;Bolong Xu.;Heli Patel.;Valentin Fauveau.;Jo Hsuan Lee.;Oren Cohen.;Samira Khan.;Philip M Robson.;Hayit Greenspan.;Mayte Suárez-Fariñas.;Neomi A Shah.;Vaishnavi Kundel.
来源: Chest. 2026年
Obesity is a major risk factor for obstructive sleep apnea (OSA), and visceral adiposity may mediate its cardiometabolic consequences. However, studies evaluating the impact of continuous positive airway pressure (CPAP) on visceral obesity have yielded conflicting results.
19. Diaphragm Thickening Fraction Fails to Predict Esophageal Pressure or Ventilator Weaning in Children.
作者: Daniel J Chang.;Marsha Elkhunovich.;Justin C Hotz.;Dinnel Bornstein.;Kristen Kohler.;Anabel Armenta-Quiroz.;Kennedy Vu.;Erin Smith.;Anil Suresh.;Yukie Ito.;Anoopindar Bhalla.;Christopher J L Newth.;Robinder G Khemani.
来源: Chest. 2026年
Studies relating diaphragm thickening fraction (DTF), delta esophageal pressure (dPes), and weaning outcomes are lacking in critically ill children.
20. Evaluation of Lung Disease in Adults with Osteogenesis Imperfecta: A Cross-Sectional, Multi-Center Study.
作者: Chloe E Derocher.;Erin M Carter.;Debra Dyer.;Deborah Krakow.;Malinda Wu.;Robert A Sandhaus.;Cathleen L Raggio.
来源: Chest. 2026年
Osteogenesis imperfecta (OI) is a group of hereditary connective tissue disorders characterized by frequent fractures. Although cardiopulmonary impairment is a leading cause of mortality in the OI population, our understanding of the etiology of cardiopulmonary issues in OI remains limited.
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