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1901. General Capillary Endothelial Cells Undergo Reprogramming Into Arterial Endothelial Cells in Pulmonary Hypertension Through HIF-2α/Notch4 Pathway.
作者: Bin Liu.;Dan Yi.;Xiaomei Xia.;Karina Ramirez.;Hanqiu Zhao.;Yanhong Cao.;Ankit Tripathi.;Ryan Dong.;Anton Gao.;Hongxu Ding.;Shenfeng Qiu.;Vladimir V Kalinichenko.;You-Yang Zhao.;Michael B Fallon.;Zhiyu Dai.
来源: Circulation. 2024年150卷5期414-417页 1903. High-Risk Nonclassical Long-QT Syndrome Genotypes: Spectrum of Genetic and Phenotypic Features.
作者: Abdulkarim Abdulrahman.;Brianna Davies.;Habib Khan.;Shubhayan Sanatani.;Rafik Tadros.;Mario Talajic.;Julia Cadrin-Tourigny.;Joseph Atallah.;David Lee.;Martin Gardner.;Christian Steinberg.;Simon Hansom.;Martin Green.;Anne Fournier.;Laura Arbour.;Richard Leather.;Shane Kimber.;Jason Roberts.;Jeffrey Healey.;Paul Angaran.;Christopher Simpson.;Colette Seifer.;Erkan Ilhan.;Jacqueline Joza.;Andrew Krahn.;Zachary Laksman.
来源: Circ Genom Precis Med. 2024年17卷4期e004554页 1904. Letter by Lee et al Regarding Article, "Three-Year Outcomes With Fractional Flow Reserve-Guided or Angiography-Guided Multivessel Percutaneous Coronary Intervention for Myocardial Infarction".1905. Prediction of Positive Genetic Testing for Arrhythmogenic Left Ventricular Cardiomyopathy.
作者: Youssef Ed Demri.;Clarisse Billon.;Mohamed El Hachmi.;Mohamed Dembélé.;Albert Hagège.;Pascale Richard.;Flavie Ader.;Diala Khraiche.;Damien Bonnet.;Xavier Jeunemaitre.;Karim Wahbi.
来源: Circ Genom Precis Med. 2024年17卷4期e004612页 1906. Loss of Function Variant in SMAD6 Is Associated With a Novel Phenotype of Internal Carotid Artery Dissection.
作者: Malak A Alghamdi.;Wael Alqarawi.;Essa Alharbi.;Reham M Balahmar.;Haya Alruqi.;Nisserin Jadu.;Majid Alhomidan.;Mohammed Hussien Alghamdi.;Naif A M Almontashiri.
来源: Circ Genom Precis Med. 2024年17卷4期e004686页 1907. Response to Letter Regarding Article, "Clinical Outcomes of Percutaneous Transcatheter Release of Stuck Mechanical Mitral Valve With Cerebral Embolic Protection".
作者: Vasu Nandhakumar.;Latchumanadhas Kalidoss.;Mullasari S Ajit.
来源: Circ Cardiovasc Interv. 2024年17卷9期e014522页 1908. Response to Letter Regarding Article, "Three-Year Outcomes With Fractional Flow Reserve- or Angiography-Guided Multivessel Percutaneous Coronary Intervention for Myocardial Infarction".
作者: Etienne Puymirat.;Juliette Djadi-Prat.;Nicolas Danchin.
来源: Circ Cardiovasc Interv. 2024年17卷8期e014459页 1909. Letter by Güner et al Regarding Article, "Clinical Outcomes of Percutaneous Transcatheter Release of Stuck Mechanical Mitral Valve With Cerebral Embolic Protection".1910. Single Construct Suppression and Replacement Gene Therapy for the Treatment of All CALM1-, CALM2-, and CALM3-Mediated Arrhythmia Disorders.
作者: Samantha K Hamrick.;C S John Kim.;David J Tester.;Manuela Gencarelli.;Kathryn E Tobert.;Martina Gluscevic.;Michael J Ackerman.
来源: Circ Arrhythm Electrophysiol. 2024年17卷8期e012036页
CaM (calmodulin)-mediated long-QT syndrome is a genetic arrhythmia disorder (calmodulinopathies) characterized by a high prevalence of life-threatening ventricular arrhythmias occurring early in life. Three distinct genes (CALM1, CALM2, and CALM3) encode for the identical CaM protein. Conventional pharmacotherapies fail to adequately protect against potentially lethal cardiac events in patients with calmodulinopathy.
1911. Impact of State Telehealth Parity Laws for Private Payers on Hypertension Medication Adherence Before and During the COVID-19 Pandemic.
作者: Donglan Zhang.;Jun Soo Lee.;Adebola Popoola.;Sarah Lee.;Sandra L Jackson.;Lisa M Pollack.;Xiaobei Dong.;Nicole L Therrien.;Feijun Luo.
来源: Circ Cardiovasc Qual Outcomes. 2024年17卷8期e010739页
Telehealth has emerged as an effective tool for managing common chronic conditions such as hypertension, especially during the COVID-19 pandemic. However, the impact of state telehealth payment and coverage parity laws on hypertension medication adherence remains uncertain.
1913. Outcomes With the WATCHMAN FLX in Everyday Clinical Practice From the NCDR Left Atrial Appendage Occlusion Registry.
作者: Samir R Kapadia.;Robert W Yeh.;Matthew J Price.;Jonathan P Piccini.;Devi G Nair.;Agam Bansal.;Jonathan C Hsu.;James V Freeman.;Thomas Christen.;Dominic J Allocco.;Douglas N Gibson.
来源: Circ Cardiovasc Interv. 2024年17卷9期e013750页
PINNACLE FLX (Protection Against Embolism for Nonvalvular AF Patients: Investigational Device Evaluation of the WATCHMAN FLX LAA Closure Technology) demonstrated improved outcomes and low incidence of adverse events with the WATCHMAN FLX device in a controlled setting. The National Cardiovascular Disease Registry's Left Atrial Appendage Occlusion Registry was utilized to assess the safety and effectiveness of WATCHMAN FLX in contemporary clinical practice in the United States.
1915. RNA Helicase DDX5 Maintains Cardiac Function by Regulating CamkIIδ Alternative Splicing.
作者: Kangni Jia.;Haomai Cheng.;Wenqi Ma.;Lingfang Zhuang.;Hao Li.;Zhigang Li.;Ziyang Wang.;Hang Sun.;Yuke Cui.;Hang Zhang.;Hongyang Xie.;Lei Yi.;Zhiyong Chen.;Motoaki Sano.;Keiichi Fukuda.;Lin Lu.;Jun Pu.;Yan Zhang.;Ling Gao.;Ruiyan Zhang.;Xiaoxiang Yan.
来源: Circulation. 2024年150卷14期1121-1139页
Heart failure (HF) is a leading cause of morbidity and mortality worldwide. RNA-binding proteins are identified as regulators of cardiac disease; DDX5 (dead-box helicase 5) is a master regulator of many RNA processes, although its function in heart physiology remains unclear.
1916. Change in Pd/Pa: Clinical Implications for Predicting Future Cardiac Events at Deferred Coronary Lesions.
作者: Kota Murai.;Yu Kataoka.;Eri Kiyoshige.;Takamasa Iwai.;Kenichiro Sawada.;Hideo Matama.;Hiroyuki Miura.;Satoshi Honda.;Masashi Fujino.;Shuichi Yoneda.;Kazuhiro Nakao.;Kensuke Takagi.;Fumiyuki Otsuka.;Yasuhide Asaumi.;Kunihiro Nishimura.;Teruo Noguchi.
来源: Circ Cardiovasc Interv. 2024年17卷9期e013830页
Cardiovascular events still occur at intermediate stenosis with fractional flow reserve (FFR) ≥0.81, underscoring the additional measure to evaluate this residual risk. A reduction in distal coronary artery pressure/aortic pressure (Pd/Pa) from baseline to hyperemia (ie, change in Pd/Pa) reflects lipidic burden within vessel walls. We hypothesized that this physiological measure might stratify the risk of future cardiac events at deferrable lesions.
1917. Evaluation of Ablation Parameters to Predict Irreversible Lesion Size During Pulsed Field Ablation.
作者: Hiroshi Nakagawa.;Salman Farshchi-Heydari.;Jennifer Maffre.;Tushar Sharma.;Assaf Govari.;Christopher T Beeckler.;Andres Altmann.;Atsushi Ikeda.;Masafumi Sugawara.;Warren M Jackman.;Ayman A Hussein.;Shady Nakhla.;Pasquale Santangeli.;Walid I Saliba.;Oussama M Wazni.
来源: Circ Arrhythm Electrophysiol. 2024年17卷8期e012814页
During pulsed field ablation (PFA), relationships between ablation parameters (contact force [CF], number of burst pulses, impedance decrease, and electrode temperature) and lesion size in beating hearts have not been well validated.
1918. Pathophysiologic Vasodilation in Cardiogenic Shock and Its Impact on Mortality.
作者: Miguel A Chavez.;McHale Anderson.;Christos P Kyriakopoulos.;Monte Scott.;Elizabeth Dranow.;Eleni Maneta.;Rana Hamouche.;Iosif Taleb.;Jacy Leon.;Benjamin Kogelschatz.;Jake Goldstein.;Filio Billia.;David A Baran.;Behnam Tehrani.;Matt Goodwin.;Craig H Selzman.;Joseph E Tonna.;James C Fang.;Stavros G Drakos.;Thomas C Hanff.
来源: Circ Heart Fail. 2024年17卷9期e011827页
Cardiogenic shock (CS) mortality remains near 40%. In addition to inadequate cardiac output, patients with severe CS may exhibit vasodilation. We aimed to examine the prevalence and consequences of vasodilation in CS.
1920. Direct Comparison of Methods to Differentiate Wide Complex Tachycardias: Novel Automated Algorithms Versus Manual ECG Interpretation Approaches.
作者: Sarah LoCoco.;Anthony H Kashou.;Abhishek J Deshmukh.;Samuel J Asirvatham.;Christopher V DeSimone.;Krasimira M Mikhova.;Sandeep S Sodhi.;Phillip S Cuculich.;Rugheed Ghadban.;Daniel H Cooper.;Thomas M Maddox.;Peter A Noseworthy.;Adam M May.
来源: Circ Arrhythm Electrophysiol. 2024年17卷8期e012663页
Differentiating wide complex tachycardias (WCTs) into ventricular tachycardia (VT) and supraventricular wide tachycardia via 12-lead ECG interpretation is a crucial but difficult task. Automated algorithms show promise as alternatives to manual ECG interpretation, but direct comparison of their diagnostic performance has not been undertaken.
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