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1826. FDA Perspective on the Regulation of Artificial Intelligence in Health Care and Biomedicine.
Advances in artificial intelligence (AI) must be matched by efforts to better understand and evaluate how AI performs across health care and biomedicine as well as develop appropriate regulatory frameworks. This Special Communication reviews the history of the US Food and Drug Administration's (FDA) regulation of AI; presents potential uses of AI in medical product development, clinical research, and clinical care; and presents concepts that merit consideration as the regulatory system adapts to AI's unique challenges.
1827. Testing and Evaluation of Health Care Applications of Large Language Models: A Systematic Review.
作者: Suhana Bedi.;Yutong Liu.;Lucy Orr-Ewing.;Dev Dash.;Sanmi Koyejo.;Alison Callahan.;Jason A Fries.;Michael Wornow.;Akshay Swaminathan.;Lisa Soleymani Lehmann.;Hyo Jung Hong.;Mehr Kashyap.;Akash R Chaurasia.;Nirav R Shah.;Karandeep Singh.;Troy Tazbaz.;Arnold Milstein.;Michael A Pfeffer.;Nigam H Shah.
来源: JAMA. 2025年333卷4期319-328页
Large language models (LLMs) can assist in various health care activities, but current evaluation approaches may not adequately identify the most useful application areas.
1831. Mpox Clinical Presentation, Diagnostic Approaches, and Treatment Strategies: A Review.
A global outbreak of clade IIb Monkeypox virus (MPXV) infections spread rapidly across at least 118 countries resulting in a Public Health Emergency of International Concern (PHEIC) from July 2022 to May 2023. This outbreak affected more than 99 000 persons worldwide and caused more than 33 000 infections and 60 deaths in the US. In 2024, there have been approximately 200 new infections per month in the US. On August 14, 2024, the World Health Organization declared mpox a PHEIC for a second time due to a rapid increase in infections with clade I MPXV in Central Africa.
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