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1781. Effectiveness of influenza vaccination of day care children in reducing influenza-related morbidity among household contacts.
作者: E S Hurwitz.;M Haber.;A Chang.;T Shope.;S Teo.;M Ginsberg.;N Waecker.;N J Cox.
来源: JAMA. 2000年284卷13期1677-82页
A growing proportion of young children in the United States participate in day care, and these children are considered to be at high risk for influenza infection. Whether vaccinating day care children reduces household transmission of influenza is not known.
1782. Effectiveness and cost-benefit of influenza vaccination of healthy working adults: A randomized controlled trial.
作者: C B Bridges.;W W Thompson.;M I Meltzer.;G R Reeve.;W J Talamonti.;N J Cox.;H A Lilac.;H Hall.;A Klimov.;K Fukuda.
来源: JAMA. 2000年284卷13期1655-63页
Although the cost-effectiveness and cost-benefit of influenza vaccination are well established for persons aged 65 years or older, the benefits for healthy adults younger than 65 years are less clear.
1783. Treatment of dysthymia and minor depression in primary care: A randomized controlled trial in older adults.
作者: J W Williams.;J Barrett.;T Oxman.;E Frank.;W Katon.;M Sullivan.;J Cornell.;A Sengupta.
来源: JAMA. 2000年284卷12期1519-26页
Insufficient evidence exists for recommendation of specific effective treatments for older primary care patients with minor depression or dysthymia.
1784. Improving residents' compliance with standards of ambulatory care: results from the VA Cooperative Study on Computerized Reminders.
作者: J G Demakis.;C Beauchamp.;W L Cull.;R Denwood.;S A Eisen.;R Lofgren.;K Nichol.;J Woolliscroft.;W G Henderson.
来源: JAMA. 2000年284卷11期1411-6页
Computerized systems to remind physicians to provide appropriate care have not been widely evaluated in large numbers of patients in multiple clinical settings.
1785. Preventing child abuse and neglect with a program of nurse home visitation: the limiting effects of domestic violence.
作者: J Eckenrode.;B Ganzel.;C R Henderson.;E Smith.;D L Olds.;J Powers.;R Cole.;H Kitzman.;K Sidora.
来源: JAMA. 2000年284卷11期1385-91页
Home visitation to families with young children has been promoted as an effective way to prevent child maltreatment, but few studies have examined the conditions under which such programs meet this goal.
1787. Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: A randomized trial. Arterial Disease Multiple Intervention Trial.
作者: M B Elam.;D B Hunninghake.;K B Davis.;R Garg.;C Johnson.;D Egan.;J B Kostis.;D S Sheps.;E A Brinton.
来源: JAMA. 2000年284卷10期1263-70页
Although niacin increases low levels of high-density lipoprotein cholesterol (HDL-C), which frequently accompany diabetes, current guidelines do not recommend use of niacin in patients with diabetes because of concerns about adverse effects on glycemic control; however, this is based on limited clinical data.
1788. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.
作者: F E Silverstein.;G Faich.;J L Goldstein.;L S Simon.;T Pincus.;A Whelton.;R Makuch.;G Eisen.;N M Agrawal.;W F Stenson.;A M Burr.;W W Zhao.;J D Kent.;J B Lefkowith.;K M Verburg.;G S Geis.
来源: JAMA. 2000年284卷10期1247-55页
Conventional nonsteroidal anti-inflammatory drugs (NSAIDs) are associated with a spectrum of toxic effects, notably gastrointestinal (GI) effects, because of inhibition of cyclooxygenase (COX)-1. Whether COX-2-specific inhibitors are associated with fewer clinical GI toxic effects is unknown.
1790. Neurological development of 5-year-old children receiving a low-saturated fat, low-cholesterol diet since infancy: A randomized controlled trial.
作者: L Rask-Nissilä.;E Jokinen.;P Terho.;A Tammi.;H Lapinleimu.;T Rönnemaa.;J Viikari.;R Seppänen.;T Korhonen.;J Tuominen.;I Välimäki.;O Simell.
来源: JAMA. 2000年284卷8期993-1000页
Early childhood introduction of nutritional habits aimed at atherosclerosis prevention is compatible with normal growth, but its effect on neurological development is unknown.
1791. Ondansetron for reduction of drinking among biologically predisposed alcoholic patients: A randomized controlled trial.
作者: B A Johnson.;J D Roache.;M A Javors.;C C DiClemente.;C R Cloninger.;T J Prihoda.;P S Bordnick.;N Ait-Daoud.;J Hensler.
来源: JAMA. 2000年284卷8期963-71页
Early-onset alcoholism differs from late-onset alcoholism by its association with greater serotonergic abnormality and antisocial behaviors. Thus, individuals with early-onset alcoholism may be responsive to treatment with a selective serotonergic agent.
1792. The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making.
作者: E M Antman.;M Cohen.;P J Bernink.;C H McCabe.;T Horacek.;G Papuchis.;B Mautner.;R Corbalan.;D Radley.;E Braunwald.
来源: JAMA. 2000年284卷7期835-42页
Patients with unstable angina/non-ST-segment elevation myocardial infarction (MI) (UA/NSTEMI) present with a wide spectrum of risk for death and cardiac ischemic events.
1794. Metformin in the treatment of HIV lipodystrophy syndrome: A randomized controlled trial.
A syndrome of lipodystrophy, characterized by fat redistribution and insulin resistance, has been estimated to affect the majority of human immunodeficiency virus (HIV)-infected individuals who are treated with combination antiretroviral therapy. There are no proven therapies for the metabolic disturbances associated with HIV lipodystrophy syndrome.
1795. Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke: the Systolic Hypertension in the Elderly Program (SHEP).
作者: H M Perry.;B R Davis.;T R Price.;W B Applegate.;W S Fields.;J M Guralnik.;L Kuller.;S Pressel.;J Stamler.;J L Probstfield.
来源: JAMA. 2000年284卷4期465-71页
The Systolic Hypertension in the Elderly Program (SHEP) demonstrated that treating isolated systolic hypertension in older patients decreased incidence of total stroke, but whether all types of stroke were reduced was not evaluated.
1796. Immunologic and virologic effects of subcutaneous interleukin 2 in combination with antiretroviral therapy: A randomized controlled trial.
作者: R T Davey.;R L Murphy.;F M Graziano.;S L Boswell.;A T Pavia.;M Cancio.;J P Nadler.;D G Chaitt.;R L Dewar.;D K Sahner.;A M Duliege.;W B Capra.;W P Leong.;M A Giedlin.;H C Lane.;J O Kahn.
来源: JAMA. 2000年284卷2期183-9页
While interleukin 2 (IL-2) is capable of inducing a marked expansion of the CD4 T-lymphocyte pool, limited data exist on whether IL-2 treatment can add significantly to the immunologic and virologic effects of potent antiretroviral therapy (ART).
1798. Effect of a community intervention on patient delay and emergency medical service use in acute coronary heart disease: The Rapid Early Action for Coronary Treatment (REACT) Trial.
作者: R V Luepker.;J M Raczynski.;S Osganian.;R J Goldberg.;J R Finnegan.;J R Hedges.;D C Goff.;M S Eisenberg.;J G Zapka.;H A Feldman.;D R Labarthe.;P G McGovern.;C E Cornell.;M A Proschan.;D G Simons-Morton.
来源: JAMA. 2000年284卷1期60-7页
Delayed access to medical care in patients with acute myocardial infarction (AMI) is common and increases myocardial damage and mortality.
1799. Effect of a monetary sanction on immunization rates of recipients of aid to families with dependent children.
Immunization rates among low-income families have lagged behind those for the general community, with several possible barriers cited in the literature.
1800. Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure: A randomized trial.
作者: R Hambrecht.;S Gielen.;A Linke.;E Fiehn.;J Yu.;C Walther.;N Schoene.;G Schuler.
来源: JAMA. 2000年283卷23期3095-101页
Exercise training in patients with chronic heart failure improves work capacity by enhancing endothelial function and skeletal muscle aerobic metabolism, but effects on central hemodynamic function are not well established.
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