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161. Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps.
作者: Jeffrey S A Stringer.;Teeranan Pokaprakarn.;Juan C Prieto.;Bellington Vwalika.;Srihari V Chari.;Ntazana Sindano.;Bethany L Freeman.;Bridget Sikapande.;Nicole M Davis.;Yuri V Sebastião.;Nelly M Mandona.;Elizabeth M Stringer.;Chiraz Benabdelkader.;Mutinta Mungole.;Filson M Kapilya.;Nariman Almnini.;Arieska N Diaz.;Brittany A Fecteau.;Michael R Kosorok.;Stephen R Cole.;Margaret P Kasaro.
来源: JAMA. 2024年332卷8期649-657页
Accurate assessment of gestational age (GA) is essential to good pregnancy care but often requires ultrasonography, which may not be available in low-resource settings. This study developed a deep learning artificial intelligence (AI) model to estimate GA from blind ultrasonography sweeps and incorporated it into the software of a low-cost, battery-powered device.
164. Midcareer Satisfaction and Likelihood of Leaving Current Position of Former Career Development Awardees.
作者: Reshma Jagsi.;Kent A Griffith.;Kelly C Paradis.;Patricia Mae G Santos.;Mylin A Torres.;Rochelle D Jones.;Eve A Kerr.
来源: JAMA. 2024年332卷8期666-667页 165. Projected Changes in Statin and Antihypertensive Therapy Eligibility With the AHA PREVENT Cardiovascular Risk Equations.
作者: James A Diao.;Ivy Shi.;Venkatesh L Murthy.;Thomas A Buckley.;Chirag J Patel.;Emma Pierson.;Robert W Yeh.;Dhruv S Kazi.;Rishi K Wadhera.;Arjun K Manrai.
来源: JAMA. 2024年332卷12期989-1000页
Since 2013, the American College of Cardiology (ACC) and American Heart Association (AHA) have recommended the pooled cohort equations (PCEs) for estimating the 10-year risk of atherosclerotic cardiovascular disease (ASCVD). An AHA scientific advisory group recently developed the Predicting Risk of cardiovascular disease EVENTs (PREVENT) equations, which incorporated kidney measures, removed race as an input, and improved calibration in contemporary populations. PREVENT is known to produce ASCVD risk predictions that are lower than those produced by the PCEs, but the potential clinical implications have not been quantified.
166. Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care.
作者: Sebastian Palmqvist.;Pontus Tideman.;Niklas Mattsson-Carlgren.;Suzanne E Schindler.;Ruben Smith.;Rik Ossenkoppele.;Susanna Calling.;Tim West.;Mark Monane.;Philip B Verghese.;Joel B Braunstein.;Kaj Blennow.;Shorena Janelidze.;Erik Stomrud.;Gemma Salvadó.;Oskar Hansson.
来源: JAMA. 2024年332卷15期1245-1257页
An accurate blood test for Alzheimer disease (AD) could streamline the diagnostic workup and treatment of AD.
167. Changes in Alzheimer Disease Blood Biomarkers and Associations With Incident All-Cause Dementia.
作者: Yifei Lu.;James Russell Pike.;Jinyu Chen.;Keenan A Walker.;Kevin J Sullivan.;Bharat Thyagarajan.;Michelle M Mielke.;Pamela L Lutsey.;David Knopman.;Rebecca F Gottesman.;A Richey Sharrett.;Josef Coresh.;Thomas H Mosley.;Priya Palta.
来源: JAMA. 2024年332卷15期1258-1269页
Plasma biomarkers show promise for identifying Alzheimer disease (AD) neuropathology and neurodegeneration, but additional examination among diverse populations and throughout the life course is needed.
170. Effect of Cash Benefits on Health Care Utilization and Health: A Randomized Study.
Poverty is associated with greater barriers to health care and worse health outcomes, but it remains unclear whether income support can improve health.
172. Risankizumab for Ulcerative Colitis: Two Randomized Clinical Trials.
作者: Edouard Louis.;Stefan Schreiber.;Remo Panaccione.;Peter Bossuyt.;Luc Biedermann.;Jean-Frederic Colombel.;Gareth Parkes.;Laurent Peyrin-Biroulet.;Geert D'Haens.;Tadakazu Hisamatsu.;Britta Siegmund.;Kaichun Wu.;Brigid S Boland.;Gil Y Melmed.;Alessandro Armuzzi.;Phillip Levine.;Jasmina Kalabic.;Su Chen.;Ling Cheng.;Lei Shu.;W Rachel Duan.;Valerie Pivorunas.;Yuri Sanchez Gonzalez.;Ronilda D'Cunha.;Ezequiel Neimark.;Kori Wallace.;Raja Atreya.;Marc Ferrante.;Edward V Loftus.; .
来源: JAMA. 2024年332卷11期881-897页
The clinical effects of risankizumab (a monoclonal antibody that selectively targets the p19 subunit of IL-23) for the treatment of ulcerative colitis are unknown.
173. Endometriosis Typology and Ovarian Cancer Risk.
作者: Mollie E Barnard.;Leslie V Farland.;Bin Yan.;Jing Wang.;Britton Trabert.;Jennifer A Doherty.;Huong D Meeks.;Myke Madsen.;Emily Guinto.;Lindsay J Collin.;Kathryn A Maurer.;Jessica M Page.;Amber C Kiser.;Michael W Varner.;Kristina Allen-Brady.;Anna Z Pollack.;Kurt R Peterson.;C Matthew Peterson.;Karen C Schliep.
来源: JAMA. 2024年332卷6期482-489页
Endometriosis has been associated with an increased risk of ovarian cancer; however, the associations between endometriosis subtypes and ovarian cancer histotypes have not been well-described.
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