1683. Tenofovir and Hepatitis B Virus Transmission During Pregnancy: A Randomized Clinical Trial.
作者: Calvin Q Pan.;Erhei Dai.;Zhongfu Mo.;Hua Zhang.;Thomas Q Zheng.;Yuming Wang.;Yingxia Liu.;Tianyan Chen.;Suwen Li.;Cuili Yang.;Jinjuan Wu.;Xiuli Chen.;Huaibin Zou.;Shanshan Mei.;Lin Zhu.
来源: JAMA. 2025年333卷5期390-399页
Standard care for preventing mother-to-child transmission (MTCT) of hepatitis B virus (HBV) in highly viremic mothers consists of maternal antiviral prophylaxis beginning at gestational week 28 combined with an HBV vaccine series and HBV immune globulin (HBIG) at birth. However, HBIG is unavailable in some resource-limited areas.
1685. Artemisinin Partial Resistance in Ugandan Children With Complicated Malaria.
作者: Ryan C Henrici.;Ruth Namazzi.;Giselle Lima-Cooper.;Charles Kato.;Sadati Aliwuya.;Jamille G Dombrowski.;Sade Pratt.;Susana Campino.;Andrea L Conroy.;Colin J Sutherland.;Chandy C John.;Robert O Opoka.
来源: JAMA. 2025年333卷1期83-84页 1689. Symptom Screening Linked to Care Pathways for Pediatric Patients With Cancer: A Randomized Clinical Trial.
作者: L Lee Dupuis.;Emily Vettese.;Allison C Grimes.;Melissa P Beauchemin.;Lisa M Klesges.;Christina Baggott.;Jenna Demedis.;Catherine Aftandilian.;David R Freyer.;Nicole Crellin-Parsons.;Etan Orgel.;David Dickens.;Kara M Kelly.;Wade Kyono.;Alexandra Walsh.;Farha Sherani.;Daniel Cannone.;Andrea D Orsey.;Allison A King.;Lolie Yu.;Wendy Woods-Swafford.;Scott M Bradfield.;Michael E Roth.;Adam J Esbenshade.;Emi H Caywood.;Vibhuti Agarwal.;Ramamoorthy Nagasubramanian.;George A Tomlinson.;Lillian Sung.
来源: JAMA. 2024年332卷23期1981-1991页
Pediatric patients with cancer commonly experience severely bothersome symptoms. The effectiveness of routine symptom screening with symptom feedback and symptom management care pathways is unknown.
1694. Intratracheal Budesonide Mixed With Surfactant for Extremely Preterm Infants: The PLUSS Randomized Clinical Trial.
作者: Brett J Manley.;C Omar F Kamlin.;Susan M Donath.;Kate L Francis.;Jeanie L Y Cheong.;Peter A Dargaville.;Jennifer A Dawson.;Susan E Jacobs.;Pita Birch.;Steven M Resnick.;Georg M Schmölzer.;Brenda Law.;Risha Bhatia.;Katinka P Bach.;Koert de Waal.;Javeed N Travadi.;Pieter J Koorts.;Mary J Berry.;Kei Lui.;Victor S Rajadurai.;Suresh Chandran.;Martin Kluckow.;Elza Cloete.;Margaret M Broom.;Michael J Stark.;Adrienne Gordon.;Vinayak Kodur.;Lex W Doyle.;Peter G Davis.;Christopher J D McKinlay.; .
来源: JAMA. 2024年332卷22期1889-1899页
Bronchopulmonary dysplasia (BPD) is a common adverse outcome in extremely preterm infants born at less than 28 weeks' gestation. Systemic corticosteroids are effective against BPD but may be associated with adverse outcomes. Corticosteroids given directly into the lungs may be effective and safer.
1696. Online Retailer Nonadherence to Age Verification, Shipping, and Flavor Restrictions on E-Cigarettes.
作者: Raquel M Harati.;Shannon E Ellis.;Nora Satybaldiyeva.;Tomas Mejorado.;Gustavo Benitez.;Lisa Henriksen.;Eric C Leas.
来源: JAMA. 2024年332卷24期2113-2114页 1697. Calcific Aortic Stenosis: A Review.
Calcific aortic stenosis (AS) restricts the aortic valve opening during systole due to calcification and fibrosis of either a congenital bicuspid or a normal trileaflet aortic valve. In the US, AS affects 1% to 2% of adults older than 65 years and approximately 12% of adults older than 75 years. Worldwide, AS leads to more than 100 000 deaths annually.
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