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142. High-Dose Spironolactone When Patients With Acute Decompensated Heart Failure Are Resistant to Loop Diuretics: A Pilot Study.
作者: Shweta Bansal.;Kristina Munoz.;Sonja Brune.;Steven Bailey.;Anand Prasad.;Chakradhar Velagapudi.
来源: Ann Intern Med. 2019年171卷6期443-447页 143. Continuous Anticoagulation and Cold Snare Polypectomy Versus Heparin Bridging and Hot Snare Polypectomy in Patients on Anticoagulants With Subcentimeter Polyps: A Randomized Controlled Trial.
作者: Yoji Takeuchi.;Katsuhiro Mabe.;Yuichi Shimodate.;Shinji Yoshii.;Shinya Yamada.;Mineo Iwatate.;Takuji Kawamura.;Kinichi Hotta.;Koji Nagaike.;Nobuaki Ikezawa.;Tomoaki Yamasaki.;Yoriaki Komeda.;Satoshi Asai.;Yasuhiro Abe.;Takuji Akamatsu.;Yuko Sakakibara.;Hisatomo Ikehara.;Yuzuru Kinjo.;Takashi Ohta.;Yoko Kitamura.;Takashi Shono.;Takuya Inoue.;Yoshio Ohda.;Nozomu Kobayashi.;Tokuma Tanuma.;Ryu Sato.;Taku Sakamoto.;Naohiko Harada.;Akiko Chino.;Hideki Ishikawa.;Masanori Nojima.;Toshio Uraoka.; .
来源: Ann Intern Med. 2019年171卷4期229-237页
Management of anticoagulants for patients undergoing polypectomy is still controversial. Cold snare polypectomy (CSP) is reported to cause less bleeding than hot snare polypectomy (HSP).
144. Mavacamten Treatment for Obstructive Hypertrophic Cardiomyopathy: A Clinical Trial.
作者: Stephen B Heitner.;Daniel Jacoby.;Steven J Lester.;Anjali Owens.;Andrew Wang.;David Zhang.;Joseph Lambing.;June Lee.;Marc Semigran.;Amy J Sehnert.
来源: Ann Intern Med. 2019年170卷11期741-748页
Mavacamten, an orally administered, small-molecule modulator of cardiac myosin, targets underlying biomechanical abnormalities in obstructive hypertrophic cardiomyopathy (oHCM).
145. Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study.
作者: John W Apolzan.;Elizabeth M Venditti.;Sharon L Edelstein.;William C Knowler.;Dana Dabelea.;Edward J Boyko.;Xavier Pi-Sunyer.;Rita R Kalyani.;Paul W Franks.;Preethi Srikanthan.;Kishore M Gadde.; .
来源: Ann Intern Med. 2019年170卷10期682-690页
Identifying reliable predictors of long-term weight loss (LTWL) could lead to improved weight management.
146. Intensive Models of Hepatitis C Care for People Who Inject Drugs Receiving Opioid Agonist Therapy: A Randomized Controlled Trial.
作者: Matthew J Akiyama.;Brianna L Norton.;Julia H Arnsten.;Linda Agyemang.;Moonseong Heo.;Alain H Litwin.
来源: Ann Intern Med. 2019年170卷9期594-603页
Many people who inject drugs (PWID) are denied treatment for hepatitis C virus (HCV) infection, even if they are receiving opioid agonist therapy (OAT). Research suggests that HCV in PWID may be treated effectively, but optimal models of care for promoting adherence and sustained virologic response (SVR) have not been evaluated in the direct-acting antiviral (DAA) era.
147. Medical Graphic Narratives to Improve Patient Comprehension and Periprocedural Anxiety Before Coronary Angiography and Percutaneous Coronary Intervention: A Randomized Trial.
作者: Anna Brand.;Linde Gao.;Alexandra Hamann.;Claudia Crayen.;Hannah Brand.;Susan M Squier.;Karl Stangl.;Friederike Kendel.;Verena Stangl.
来源: Ann Intern Med. 2019年170卷8期579-581页 148. B-Lymphocyte Depletion in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
作者: Øystein Fluge.;Ingrid G Rekeland.;Katarina Lien.;Hanne Thürmer.;Petter C Borchgrevink.;Christoph Schäfer.;Kari Sørland.;Jörg Aßmus.;Irini Ktoridou-Valen.;Ingrid Herder.;Merethe E Gotaas.;Øivind Kvammen.;Katarzyna A Baranowska.;Louis M L J Bohnen.;Sissel S Martinsen.;Ann E Lonar.;Ann-Elise H Solvang.;Arne E S Gya.;Ove Bruland.;Kristin Risa.;Kine Alme.;Olav Dahl.;Olav Mella.
来源: Ann Intern Med. 2019年170卷9期585-593页
Previous phase 2 trials indicated benefit from B-lymphocyte depletion in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
149. Thyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms: A Randomized Trial.
作者: Ivar Guldvog.;Laurens Cornelus Reitsma.;Lene Johnsen.;Andromeda Lauzike.;Charlotte Gibbs.;Eivind Carlsen.;Tone Hoel Lende.;Jon Kristian Narvestad.;Roald Omdal.;Jan Terje Kvaløy.;Geir Hoff.;Tomm Bernklev.;Håvard Søiland.
来源: Ann Intern Med. 2019年170卷7期453-464页
Hashimoto disease is a chronic autoimmune thyroiditis. Despite adequate hormone substitution, some patients have persistent symptoms that may be the result of immunologic pathophysiology.
150. Comparative Efficacy of Therapies for Treatment of Depression for Patients Undergoing Maintenance Hemodialysis: A Randomized Clinical Trial.
作者: Rajnish Mehrotra.;Daniel Cukor.;Mark Unruh.;Tessa Rue.;Patrick Heagerty.;Scott D Cohen.;Laura M Dember.;Yaminette Diaz-Linhart.;Amelia Dubovsky.;Tom Greene.;Nancy Grote.;Nancy Kutner.;Madhukar H Trivedi.;Davin K Quinn.;Nisha Ver Halen.;Steven D Weisbord.;Bessie A Young.;Paul L Kimmel.;S Susan Hedayati.
来源: Ann Intern Med. 2019年170卷6期369-379页
Although depression is common among patients receiving maintenance hemodialysis, data on their acceptance of treatment and on the comparative efficacy of various therapies are limited.
151. Effects of a Personalized Web-Based Decision Aid for Surrogate Decision Makers of Patients With Prolonged Mechanical Ventilation: A Randomized Clinical Trial.
作者: Christopher E Cox.;Douglas B White.;Catherine L Hough.;Derek M Jones.;Jeremy M Kahn.;Maren K Olsen.;Carmen L Lewis.;Laura C Hanson.;Shannon S Carson.
来源: Ann Intern Med. 2019年170卷5期285-297页
Treatment decisions commonly have to be made in intensive care units (ICUs). These decisions are difficult for surrogate decision makers and often lead to decisional conflict, psychological distress, and treatments misaligned with patient preferences.
152. Cost-Effectiveness of Buprenorphine-Naloxone Versus Extended-Release Naltrexone to Prevent Opioid Relapse.
作者: Sean M Murphy.;Kathryn E McCollister.;Jared A Leff.;Xuan Yang.;Philip J Jeng.;Joshua D Lee.;Edward V Nunes.;Patricia Novo.;John Rotrosen.;Bruce R Schackman.
来源: Ann Intern Med. 2019年170卷2期90-98页
Not enough evidence exists to compare buprenorphine-naloxone with extended-release naltrexone for treating opioid use disorder.
153. Effectiveness and Safety of Reference Infliximab and Biosimilar in Crohn Disease: A French Equivalence Study.
作者: Antoine Meyer.;Jérémie Rudant.;Jérôme Drouin.;Alain Weill.;Franck Carbonnel.;Joël Coste.
来源: Ann Intern Med. 2019年170卷2期99-107页
CT-P13 is a biosimilar of the reference product (RP) infliximab, with demonstrated efficacy and safety for some inflammatory arthritides. It was approved for the treatment of Crohn disease (CD) on that basis, without specific studies examining its effects in CD.
154. Effect of Liraglutide on Cardiovascular Outcomes in Elderly Patients: A Post Hoc Analysis of a Randomized Controlled Trial.
作者: Matthew P Gilbert.;Stephen C Bain.;Edward Franek.;Esteban Jodar-Gimeno.;Michael A Nauck.;Richard Pratley.;Rosângela Roginski Réa.;José Francisco Kerr Saraiva.;Søren Rasmussen.;Karen Tornøe.;Bernt Johan von Scholten.;John B Buse.; .
来源: Ann Intern Med. 2019年170卷6期423-426页 155. Long-Term Protection After Fractional-Dose Yellow Fever Vaccination: Follow-up Study of a Randomized, Controlled, Noninferiority Trial.
作者: Anna H E Roukens.;Karlijn van Halem.;Adriëtte W de Visser.;Leo G Visser.
来源: Ann Intern Med. 2018年169卷11期761-765页
Outbreaks of yellow fever and a frequently depleted vaccine stock increase demand for a dose-sparing strategy. A fractional dose of 17D yellow fever virus (17D-YFV) vaccine has been shown to be noninferior to the standard dose in inducing seroprotection.
156. Increasing Safe Outpatient Management of Emergency Department Patients With Pulmonary Embolism: A Controlled Pragmatic Trial.
作者: David R Vinson.;Dustin G Mark.;Uli K Chettipally.;Jie Huang.;Adina S Rauchwerger.;Mary E Reed.;James S Lin.;Mamata V Kene.;David H Wang.;Dana R Sax.;Tamara S Pleshakov.;Ian D McLachlan.;Cyrus K Yamin.;Andrew R Elms.;Hilary R Iskin.;Ridhima Vemula.;Donald M Yealy.;Dustin W Ballard.; .
来源: Ann Intern Med. 2018年169卷12期855-865页
Many low-risk patients with acute pulmonary embolism (PE) in the emergency department (ED) are eligible for outpatient care but are hospitalized nonetheless. One impediment to home discharge is the difficulty of identifying which patients can safely forgo hospitalization.
157. On-Demand Sildenafil as a Treatment for Raynaud Phenomenon: A Series of n-of-1 Trials.
作者: Matthieu Roustit.;Joris Giai.;Olivier Gaget.;Charles Khouri.;Myriam Mouhib.;Adrien Lotito.;Sophie Blaise.;Christophe Seinturier.;Fabien Subtil.;Adeline Paris.;Claire Cracowski.;Bernard Imbert.;Patrick Carpentier.;Sunita Vohra.;Jean-Luc Cracowski.
来源: Ann Intern Med. 2018年169卷10期694-703页
Treatment of Raynaud phenomenon (RP) with phosphodiesterase-5 inhibitors has shown moderate efficacy. Adverse effects decrease the risk-benefit profile of these drugs, and patients may not be willing to receive long-term treatment. On-demand single doses before or during exposure to cold may be a good alternative.
158. Kidney Damage Biomarkers and Incident Chronic Kidney Disease During Blood Pressure Reduction: A Case-Control Study.
作者: William R Zhang.;Timothy E Craven.;Rakesh Malhotra.;Alfred K Cheung.;Michel Chonchol.;Paul Drawz.;Mark J Sarnak.;Chirag R Parikh.;Michael G Shlipak.;Joachim H Ix.; .
来源: Ann Intern Med. 2018年169卷9期610-618页
Whether the increased incidence of chronic kidney disease (CKD) during intensive systolic blood pressure (SBP) lowering is accompanied by intrinsic kidney injury is unknown.
159. Relationship of Interleukin-1β Blockade With Incident Gout and Serum Uric Acid Levels: Exploratory Analysis of a Randomized Controlled Trial.
作者: Daniel H Solomon.;Robert J Glynn.;Jean G MacFadyen.;Peter Libby.;Tom Thuren.;Brendan M Everett.;Paul M Ridker.
来源: Ann Intern Med. 2018年169卷8期535-542页
Although studies have shown that interleukin-1β (IL-1β) inhibitors can shorten gout attacks, whether they can prevent gout attacks is unclear.
160. Twelve-Month Outcomes After Transplant of Hepatitis C-Infected Kidneys Into Uninfected Recipients: A Single-Group Trial.
作者: Peter P Reese.;Peter L Abt.;Emily A Blumberg.;Vivianna M Van Deerlin.;Roy D Bloom.;Vishnu S Potluri.;Matthew Levine.;Paige Porrett.;Deirdre Sawinski.;Susanna M Nazarian.;Ali Naji.;Richard Hasz.;Lawrence Suplee.;Jennifer Trofe-Clark.;Anna Sicilia.;Maureen McCauley.;Caren Gentile.;Jennifer Smith.;Bijan A Niknam.;Melissa Bleicher.;K Rajender Reddy.;David S Goldberg.
来源: Ann Intern Med. 2018年169卷5期273-281页
Organs from hepatitis C virus (HCV)-infected deceased donors are often discarded. Preliminary data from 2 small trials, including THINKER-1 (Transplanting Hepatitis C kidneys Into Negative KidnEy Recipients), suggested that HCV-infected kidneys could be safely transplanted into HCV-negative patients. However, intermediate-term data on quality of life and renal function are needed to counsel patients about risk.
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