125. Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury: The BICARICU-2 Randomized Clinical Trial.
作者: Boris Jung.;Mathieu Jabaudon.;Audrey De Jong.;Laurent Bitker.;Jules Audard.;Kada Klouche.;Benjamine Sarton.;Christophe Guitton.;Sigismond Lasocki.;Benjamin Rieu.;Emmanuel Canet.;Caroline Jeantrelle.;Antoine Roquilly.;Julien Mayaux.;Franck Verdonk.;Julien Pottecher.;Martine Ferrandiere.;Beatrice Riu.;Pierre Garcon.;Mona Assefi.;Philippe Detouche.;Jean Marie Forel.;Claire Roger.;Jeremy Bourenne.;Sophie Jacquier.;David Bougon.;Amelie Rolle.;Philippe Corne.;Nacim Benchabane.;Jean Christophe Richard.;Karim Asehnoune.;Gerald Chanques.;Jean Reignier.;Foud Belafia.;Maxime Fosset.;Helena Huguet.;Emmanuel Futier.;Nicolas Molinari.;Samir Jaber.; .
来源: JAMA. 2025年
The effect of sodium bicarbonate infusion on outcome in patients with severe metabolic acidemia and moderate to severe acute kidney injury is unknown.
128. An AI-Powered Lifestyle Intervention vs Human Coaching in the Diabetes Prevention Program: A Randomized Clinical Trial.
作者: Nestoras Mathioudakis.;Benjamin Lalani.;Mohammed S Abusamaan.;Mary Alderfer.;Defne Alver.;Adrian Dobs.;Brian Kane.;John McGready.;Kristin Riekert.;Benjamin Ringham.;Aliyah Shehadeh.;Fatmata Vandi.;Amal A Wanigatunga.;Daniel Zade.;Nisa M Maruthur.; .
来源: JAMA. 2025年
Prediabetes is common, yet evidence-based lifestyle interventions are underutilized.
137. Closed-Loop Insulin Delivery in Type 1 Diabetes in Pregnancy: The CIRCUIT Randomized Clinical Trial.
作者: Lois E Donovan.;Patricia Lemieux.;Amy D Dunlop.;Jennifer M Yamamoto.;Helen R Murphy.;David Simmons.;Rhonda C Bell.;Kathleen H Chaput.;Jamie L Benham.;Glynis P Ross.;Kara A Nerenberg.;Jane E Booth.;Bruce A Perkins.;Khorshid Mohammad.;Henry N Ntanda.;James A King.;George Tomlinson.;Denice S Feig.; .
来源: JAMA. 2025年
Hyperglycemia-related pregnancy complications occur in 50% of pregnant women with type 1 diabetes. Closed-loop insulin systems improve glycemia outside of pregnancy but have had limited testing in pregnancy.
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