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122. Correction to: Histone Lactylation-Mediated Metabolic Remodeling in Vascular Smooth Muscle Cells Aggravates Aortic Aneurysm and Dissection by Promoting Lactate Accumulation.
作者: Liwei Liu.;Jinyan Zhang.;Zhen Dong.;Yikai Cui.;Xiaoyi Zou.;Hao Lai.;Jiawei Gu.;Xinyu Weng.;Xuejuan Jin.;Tianyi Qiu.;Zhiqiang Pei.;Wenxuan Hong.;Ya Huang.;Wei Luo.;Lihong Pan.;Xiaolei Sun.;Beijian Zhang.;Adilan Shalamu.;Aijun Sun.;Junbo Ge.
来源: Circulation. 2026年153卷9期e908页 125. Response by Schumacher and Cousino to Letter Regarding Article, "The Impact of Fontan Circulatory Failure on Heart Transplant Survival: A 20-Center Retrospective Cohort Study".126. Response by de Veld et al to Letter Regarding Article, "Device-Related Complications in Transvenous Versus Subcutaneous Defibrillator Therapy During Long-Term Follow-Up: The PRAETORIAN-XL Trial".
作者: Jolien A de Veld.;Reinoud E Knops.;Louise R A Olde Nordkamp.
来源: Circulation. 2026年153卷9期e267-e268页 127. Response by Shi and Chen to Letter Regarding Article, "Partnership Model of Regionalized Care for Congenital Heart Disease in Resource-Limited Settings: Results From the ASSIST Project".129. Correction to: Abstract Sun602: Lower Survival After Out-of- Hospital Cardiac Arrest in Older Females: The Joint Effect of Age and Sex.
作者: Emad Awad.;Brian Grunau.;Jim Christenson.;Lamis Alamoudi.;Karen Humphries.;Jennie Helmer.
来源: Circulation. 2026年153卷9期e907页 134. Aortic and Iliac Calcifications as Predictors of Aortic Dissection, Aneurysm Rupture, and Peripheral Vascular Disease: A Prospective Cohort Study from the DANCAVAS Trials.
作者: Cecilie Skov Petersen.;Zuzanna Karon.;Lasse M Obel.;Selma Hasific.;Anna Mejldal.;Lytfi Krasniqi.;Mie Schæffer.;Flemming H Steffensen.;Lars Frost.;Jess Lambrechtsen.;Martin Busk.;Grazina Urbonaviciene.;Kenneth Egstrup.;Marek Karon.;Lars M Rasmussen.;Jes S Lindholt.;Axel C P Diederichsen.
来源: Circulation. 2026年153卷14期1026-1037页
There is limited evidence of the relationship between aortic and iliac calcification and aortic events (aortic dissection or aneurysm rupture) and major adverse limb events (MALEs; peripheral revascularization and lower limb amputation). The aim of this population-based prospective cohort study was to investigate the association of aortic and iliac calcifications with aortic events and MALEs.
135. PAM-VT 2 Study: Long-Term Scar Evolution and Ablation Lesion Assessment by Late Gadolinium Enhancement Cardiac Magnetic Resonance After Ventricular Tachycardia Ablation.
作者: Ivo Roca-Luque.;Paz Garre.;Sara Vázquez-Calvo.;José Tomás Ortiz-Pérez.;Susana Prat-González.;Rosario Jesús Perea.;Pasquale Valerio Falzone.;Jean-Baptiste Guichard.;Mariona Regany-Closa.;Till F Althoff.;Eduard Guasch.;Jose María Tolosana.;Elena Arbelo.;Paula Sánchez-Somonte.;Levio Quinto.;Roger Borràs.;Rebeca Domingo.;Mireia Niebla.;Ana García-Alvarez.;Marta Sitges.;Josep Brugada.;Lluís Mont.;Andreu Porta-Sánchez.
来源: Circulation. 2026年153卷12期874-886页
Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) is useful for identifying ventricular tachycardia (VT) substrate in patients with structural heart disease. While preprocedural LGE-CMR is widely used for planning, the role of postprocedural LGE-CMR in evaluating VT ablation success and long-term scar evolution has been less explored. This study aimed to prospectively and systematically assess the long-term evolution of scar and ablation lesions using serial postablation LGE-CMR with long-term follow-up.
136. Shocking Practices of Pediatric Electrophysiologists: Contemporary Defibrillation Testing Data From a Multicenter National CIED Registry.
作者: Iqbal El-Assaad.;Benjamin H Hammond.;Bradley C Clark.;Ronn E Tanel.;Anne M Dubin.;Ian Law.;Bradley S Marino.;Amy Cassedy.;Elizabeth Vickers Saarel.;Maully J Shah.;Prince J Kannankeril.;Soham Dasgupta.;Douglas Y Mah.
来源: Circ Arrhythm Electrophysiol. 2026年19卷3期e014288页 137. MUTTON-HF: Rationale and Design of a Study of an Indigenous Food is Medicine Intervention.
作者: Lauren A Eberly.;Carmen George.;Sharon Sandman.;Denee Bex.;Karianne Jones.;Asia Yazzie.;Leah Gray.;Larissa Morgan.;Ada Tennison.;Conor Williams.;Matt Chandra.;Rebecca Wickre.;Bennett Wickre.;Mackenzie Bolas.;Remi Welbel.;Delaney Ignace.;Benjamin Feliciano.;DezBaa Damon-Mallette.;Erica Lindsey.;Paula Mora.;Maricruz Merino.;Enrique F Schisterman.;Sonya S Shin.
来源: Circ Heart Fail. 2026年e014013页
Nutrition insecurity is a major driver of poor cardiovascular health in Indigenous communities. Medically tailored meals may improve heart failure outcomes and quality of life. There is growing momentum among Indigenous communities to reclaim traditional precontact foods to improve cardiovascular health. In this context, utilizing community-based-participatory methods, we designed MUTTON-HF (Medically Utilized Tailored Traditional Foods to Optimize Nutrition in Heart Failure)-an Indigenous culturally and medically tailored meals program that locally sources Native produce and meat and incorporates traditional Diné (Navajo) foods and recipes.
138. Small Extracellular Vesicle External Surface Adiponectin-Mediated Adipocytes/Cardiomyocytes Communication in Diabetic Ischemic Heart Failure.
作者: Zhen Zhang.;Di Zhu.;Caihong Liu.;Lu Gan.;Jianli Zhao.;Zhijun Meng.;Peng Yao.;Demin Liu.;Guoqiang Gu.;Bernard Lopez.;Theodore A Christopher.;Yajing Wang.;Xinliang Ma.
来源: Circulation. 2026年
Mortality from acute myocardial infarction (MI) has declined significantly in the past decade for nondiabetic patients. However, both morbidity and mobility of ischemic heart failure (IHF) persistently escalate in the diabetic population via incompletely understood mechanisms. Recent studies demonstrated that small extracellular vesicles (sEVs) released from nondiabetic and diabetic adipocytes (ADps) exert opposite effects on acute myocardial ischemia and reperfusion (MI/R) injury. However, whether and how ADp sEVs may protect against post-MI remodeling and IHF, and more important, whether and how diabetes may impair this protective effect, remain unknown.
139. P16+ Cells Drive Adverse Postischemic Cardiac Remodeling Through CCL8-Mediated Recruitment of Cytotoxic Lymphocytes.
作者: Lei Yan.;Jialei Zheng.;Zhengkai Lu.;Anqi Zhu.;Min Ye.;Jufeng Meng.;Juan Tang.;Hui Zhang.
来源: Circulation. 2026年
Ischemic heart disease remains a leading cause of mortality worldwide, with adverse remodeling after myocardial infarction driven by inflammation and cardiomyocyte loss. Although cytotoxic lymphocytes exacerbate myocardial injury and P16 marks cellular senescence in diseased hearts, the cell type-specific functions of P16+ populations remain unclear.
140. Low-Dose Rivaroxaban Plus Aspirin in Patients With PAD Undergoing Lower Extremity Revascularization With and Without History of Prior Limb Revascularization: Insight From the VOYAGER-PAD Trial.
作者: Mario Enrico Canonico.;Jessica Parr.;E Sebastian Debus.;Mark R Nehler.;Manesh R Patel.;Sonia S Anand.;Mark Svet.;Connie N Hess.;Warren H Capell.;Joseph Ycas.;Julian Chen.;Michael Szarek.;Eva Muehlhofer.;Lloyd Haskell.;Scott D Berkowitz.;Rupert Bauersachs.;Marc P Bonaca.
来源: Circ Cardiovasc Interv. 2026年e015229页
Patients with peripheral artery disease (PAD) undergoing lower extremity revascularization (LER) are at high risk of major adverse limb events (MALE) and major adverse cardiovascular events. The VOYAGER-PAD trial demonstrated that rivaroxaban 2.5 mg twice daily on top of antiplatelet therapy significantly reduced this risk. Whether the risk of major adverse cardiovascular events and MALE and the effect of rivaroxaban are consistent in patients with a history of prior LER versus those without has not been described.
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