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1282. Long-Term Survival of American Joint Committee on Cancer 8th Edition Staging Descriptors for Clinical M1a Non-Small Cell Lung Cancer.
作者: Arvind Kumar.;Barry Xu.;Deepti Srinivasan.;Alexandra L Potter.;Vignesh Raman.;Michael Lanuti.;Chi-Fu Jeffrey Yang.;Hugh G Auchincloss.
来源: Chest. 2024年165卷3期725-737页
The American Joint Committee on Cancer (AJCC) 8th edition TNM staging manual for non-small cell lung cancer (NSCLC) M1a descriptors includes tumors presenting with malignant pleural or pericardial effusion (ie, M1a-Effusion), pleural or pericardial nodule(s) (ie, M1a-Pleural), or separate tumor nodule(s) in a contralateral lobe (ie, M1a-Contralateral).
1283. Unique Changes in the Incidence of Acute Chest Syndrome in Children With Sickle Cell Disease Unravel the Role of Respiratory Pathogens: A Time Series Analysis.
作者: Zein Assad.;Zaba Valtuille.;Alexis Rybak.;Florentia Kaguelidou.;Andrea Lazzati.;Emmanuelle Varon.;Luu-Ly Pham.;Léa Lenglart.;Albert Faye.;Marion Caseris.;Robert Cohen.;Corinne Levy.;Astrid Vabret.;François Gravey.;François Angoulvant.;Bérengère Koehl.;Naïm Ouldali.
来源: Chest. 2024年165卷1期150-160页
Acute chest syndrome (ACS) is a life-threatening complication of sickle cell disease (SCD). Although respiratory pathogens are frequently detected in children with ACS, their respective role in triggering the disease is still unclear. We hypothesized that the incidence of ACS followed the unprecedented population-level changes in respiratory pathogen dynamics after COVID-19-related nonpharmaceutical interventions (NPIs).
1284. The Subglottic Stenosis 6 Questionnaire: A Novel Quality-of-Life Survey Validated to Predict Need for Intervention in Patients With Idiopathic Subglottic Stenosis.
作者: Richard J Lu.;Baraa Hijaz.;Matthew R Naunheim.;Lily Stevenson.;Ramon A Franco.
来源: Chest. 2024年165卷1期161-171页
Idiopathic subglottic stenosis (iSGS) is a recurrent, chronic disease defined by fibroinflammatory narrowing of the subglottic airway. A key challenge in treatment is monitoring disease progression, which may be debilitating and unpredictable in its timing.
1286. Integration and Application of Radiologic Patterns From Clinical Practice Guidelines on Idiopathic Pulmonary Fibrosis and Fibrotic Hypersensitivity Pneumonitis.
作者: Daniel-Costin Marinescu.;Cameron J Hague.;Nestor L Muller.;Darra Murphy.;Andrew Churg.;Joanne L Wright.;Amna Al-Arnawoot.;Ana-Maria Bilawich.;Patrick Bourgouin.;Gerard Cox.;Celine Durand.;Tracy Elliot.;Jennifer Ellis.;Jolene H Fisher.;Derek Fladeland.;Amanda Grant-Orser.;Gillian C Goobie.;Zachary Guenther.;Ehsan Haider.;Nathan Hambly.;James Huynh.;Kerri A Johannson.;Geoffrey Karjala.;Nasreen Khalil.;Martin Kolb.;Jonathon Leipsic.;Stacey Lok.;Sarah MacIsaac.;Micheal McInnis.;Helene Manganas.;Veronica Marcoux.;John Mayo.;Julie Morisset.;Ciaran Scallan.;Tony Sedlic.;Shane Shapera.;Kelly Sun.;Victoria Tan.;Alyson W Wong.;Boyang Zheng.;Christopher J Ryerson.
来源: Chest. 2023年164卷6期1466-1475页
Clinical practice guidelines separately describe radiologic patterns of usual interstitial pneumonia (UIP) and fibrotic hypersensitivity pneumonitis (fHP), without direction on whether or how to apply these approaches concurrently within a single patient.
1287. Central and Peripheral Hemodynamics in Young Adults Who Use Water Pipes and the Acute Effects of Water-Pipe Use.
作者: Hassan A Chami.;Maya Diab.;Nour Zaouk.;Samir Arnaout.;Gary F Mitchell.;Hussain Isma'eel.;Alan Shihadeh.
来源: Chest. 2023年164卷6期1481-1491页
Tobacco use via water pipe (commonly referred to as water-pipe smoking [WPS]) is popular among young adults globally and exposes those who smoke to toxicants.
1289. Effect of Intraarrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Invasive Treatment: A Post Hoc Bayesian Reanalysis of a Randomized Clinical Trial.1290. Toward the Implementation of Optimal Cardiac Magnetic Resonance Risk Stratification in Pulmonary Arterial Hypertension.
作者: Lucas R Celant.;Jeroen N Wessels.;J Tim Marcus.;Lilian J Meijboom.;Harm Jan Bogaard.;Frances S de Man.;Anton Vonk Noordegraaf.
来源: Chest. 2024年165卷1期181-191页
The 2022 European Society of Cardiology/European Respiratory Society pulmonary hypertension (PH) guidelines incorporate cardiac magnetic resonance (CMR) imaging metrics in the risk stratification of patients with pulmonary arterial hypertension (PAH). Thresholds to identify patients at estimated 1-year mortality risks of < 5%, 5% to 20%, and > 20% are introduced. However, these cutoff values are mostly single center-based and require external validation.
1291. Association Between Rome Classification Among Hospitalized Patients With COPD Exacerbations and Short-Term and Intermediate-Term Outcomes.
作者: Ernesto Crisafulli.;Giulia Sartori.;Arturo Huerta.;Albert Gabarrús.;Alberto Fantin.;Néstor Soler.;Antoni Torres.
来源: Chest. 2023年164卷6期1422-1433页
Recently, the Rome proposal updated the definition of exacerbation of COPD (ECOPD). However, such severity grade has not yet demonstrated intermediate-term clinical relevance.
1293. Race-Specific Spirometry Equations Do Not Improve Models of Dyspnea and Quantitative Chest CT Phenotypes.
作者: Amy L Non.;Barbara Bailey.;Surya P Bhatt.;Richard Casaburi.;Elizabeth A Regan.;Angela Wang.;Alfonso Limon.;Chantal Rabay.;Alejandro A Diaz.;Arianne K Baldomero.;Greg Kinney.;Kendra A Young.;Ben Felts.;Carol Hand.;Douglas J Conrad.
来源: Chest. 2023年164卷6期1492-1504页
Race-specific spirometry reference equations are used globally to interpret lung function for clinical, research, and occupational purposes, but inclusion of race is under scrutiny.
1294. Preserved Ratio Impaired Spirometry and COPD Accelerate Frailty Progression: Evidence From a Prospective Cohort Study.
作者: Di He.;Mengsha Yan.;Yong Zhou.;Huiqing Ge.;Xuhui Zhang.;Yuying Xu.;Chengguo Liu.;Kejing Ying.;Yimin Zhu.
来源: Chest. 2024年165卷3期573-582页
COPD has been found to be associated with frailty. However, longitudinal evidence for associations of COPD with frailty progression is inadequate. Furthermore, recent studies revealed a new phenotype of lung function impairment: preserved ratio impaired spirometry (PRISm) findings. Associations of PRISm findings and their transitions with frailty progression are unclear.
1295. Association Between Regular Moderate to Vigorous Physical Activity Initiation Following COPD Diagnosis and Mortality: An Emulated Target Trial Using Nationwide Cohort Data.
作者: Taeyun Kim.;Hyunsoo Kim.;Sunga Kong.;Sun Hye Shin.;Juhee Cho.;Danbee Kang.;Hye Yun Park.
来源: Chest. 2024年165卷1期84-94页
Moderate to vigorous physical activity (MVPA) in patients with COPD affects their overall health outcomes, including symptom relief and improved quality of life. However, the magnitude of the effect of MVPA initiation on real-world clinical outcomes has not been well investigated.
1296. Indicators of Neighborhood-Level Socioeconomic Position and Pediatric Critical Illness.
作者: Carlie N Myers.;Aruna Chandran.;Kevin J Psoter.;Jules P Bergmann.;Panagis Galiatsatos.
来源: Chest. 2023年164卷6期1434-1443页
With recent prioritization of equity in pediatric health outcomes, a shift to examine neighborhood-level health care disparities within pediatric populations has occurred, specifically in the context of critical illness.
1297. Optimizing Vasopressin Use and Initiation Timing in Septic Shock: A Narrative Review.
This review discusses the rationale for vasopressin use, summarizes the results of clinical trials evaluating vasopressin, and focuses on the timing of vasopressin initiation to provide clinicians guidance for optimal adjunctive vasopressin initiation in patients with septic shock.
1300. Mechanical Insufflation-Exsufflation Implementation and Management, Aided by Graphics Analysis.
Mechanical insufflation-exsufflation (MIE) facilitates airway clearance to mitigate respiratory infection, decompensation, and ultimately the need for intubation and placement of a tracheostomy tube. Despite widespread adoption as a respiratory support intervention for motor neuron disease, muscular dystrophy, spinal cord injury, and other diseases associated with ventilatory pump failure and ineffective cough peak flow, there is debate in the clinical community about how to optimize settings when MIE is implemented. This article will demonstrate the clinical utility of MIE graphics in titrating the initial MIE settings, guiding upper airway and lung protective strategies and providing insight to clinicians for ongoing clinical management.
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