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101. Iron Deficiency in Adults: A Review.
Absolute iron deficiency, defined as low iron stores with or without anemia, affects approximately 2 billion people worldwide and 14% of adults in the US. Iron-deficiency anemia, defined as low hemoglobin due to low iron stores, affects approximately 1.2 billion people worldwide, including 10 million in the US.
102. Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery: The FARES-II Multicenter Randomized Clinical Trial.
作者: Keyvan Karkouti.;Jeannie L Callum.;Justyna Bartoszko.;Kenichi A Tanaka.;Sigurd Knaub.;Sukhpal Brar.;Kamrouz Ghadimi.;Antoine Rochon.;Darren Mullane.;Etienne J Couture.;Yulia Lin.;Christopher Harle.;Michelle Zeller.;Diem T T Tran.;Cristina Solomon.;Vivek Rao.;Michael Law.;Amir L Butt.;Edward P Chen.;Maria Rosal Martins.;Tarit Saha.;Andrew W Shih.;Marie-Claude Vézina.;Fuad Moussa.;Raffael Pereira Cezar Zamper.;Summer Syed.;Hakan Buyukdere.;Sylvia Werner.;Deep Grewal.;Daniel Wong.;Kofi B Vandyck.;Robert Tanzola.;Bevan Hughes.;Olivier Royer.;Sophia Wong.;Jerrold H Levy.; .
来源: JAMA. 2025年
Excessive bleeding is a common and prognostically important complication of cardiac surgery. For bleeding related to coagulation factor deficiency, frozen plasma is the most used therapy. Preliminary trials indicate that 4-factor prothrombin complex concentrate (PCC) may be a suitable alternative.
110. Long-Term Risk of Stroke After Transient Ischemic Attack or Minor Stroke: A Systematic Review and Meta-Analysis.
作者: .;Faizan Khan.;Vignan Yogendrakumar.;Ronda Lun.;Aravind Ganesh.;Philip A Barber.;Vasileios-Arsenios Lioutas.;Naja Emborg Vinding.;Ale Algra.;Christian Weimar.;Joachim Ögren.;Jodi D Edwards.;Richard H Swartz.;Angel Ois.;Eva Giralt-Steinhauer.;Andrej Netland Khanevski.;Xinyi Leng.;Xuan Tian.;Thomas W Leung.;Hong-Kyun Park.;Hee-Joon Bae.;Masahiro Kamouchi.;Tetsuro Ago.;Esmee Verburgt.;Jamie Verhoeven.;Frank-Erik de Leeuw.;Bernhard P Berghout.;M Kamran Ikram.;Karel Kostev.;William Whiteley.;Toshiyuki Uehara.;Kazuo Minematsu.;Fredrik Ildstad.;Simon Fandler-Höfler.;Karoliina Aarnio.;Bettina von Sarnowski.;Matteo Foschi.;Jing Jing.;Minyoul Baik.;Young Dae Kim.;Michele Domenico Spampinato.;Yasuhiro Hasegawa.;Kanjana Perera.;Francisco Purroy.;Dipankar Dutta.;Xiaoli Yang.;Julian Lippert.;Laura Myers.;Dawn M Bravata.;Monica Santos.;Sarah Coveney.;Carlos Garcia-Esperon.;Christopher R Levi.;Diane L Lorenzetti.;Shabnam Vatanpour.;Yongjun Wang.;Gregory W Albers.;Philippa Lavallee.;Pierre Amarenco.;Shelagh B Coutts.;Michael D Hill.
来源: JAMA. 2025年333卷17期1508-1519页
After a transient ischemic attack (TIA) or minor stroke, the long-term risk of stroke is not well-known.
113. Autosomal Dominant Polycystic Kidney Disease: A Review.
作者: Fouad T Chebib.;Christian Hanna.;Peter C Harris.;Vicente E Torres.;Neera K Dahl.
来源: JAMA. 2025年
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive development of kidney cysts and is the most common inherited kidney disorder worldwide. ADPKD accounts for 5% to 10% of kidney failure in the US and Europe, and its prevalence in the US is 9.3 per 10 000 individuals.
115. Microultrasonography-Guided vs MRI-Guided Biopsy for Prostate Cancer Diagnosis: The OPTIMUM Randomized Clinical Trial.
作者: Adam Kinnaird.;Ferdinand Luger.;Hannes Cash.;Sangeet Ghai.;L Felipe Urdaneta-Salegui.;Christian P Pavlovich.;Joseph Brito.;Neal D Shore.;Julian P Struck.;Martin Schostak.;Niklas Harland.;Moisés Rodriguez-Socarrás.;Wayne G Brisbane.;Giovanni Lughezzani.;Harry Toledano.;Mohammed Salah Ouertani.;Petr Macek.;Christopher Fung.;Wendy Tu.;Andreas Gusenleitner.;Karsten Günzel.;Peter F Incze.;Arvin K George.;José G Pereira.;Robert Jansen.;Joseph Renzulli.;Laurence Klotz.; .
来源: JAMA. 2025年
High-resolution microultrasonography-guided biopsy is an alternative to MRI fusion-guided biopsy for prostate cancer diagnosis.
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