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101. Stepped Exercise Program for Patients With Knee Osteoarthritis : A Randomized Controlled Trial.
作者: Kelli D Allen.;Sandra Woolson.;Helen M Hoenig.;Dennis Bongiorni.;James Byrd.;Kevin Caves.;Katherine S Hall.;Bryan Heiderscheit.;Nancy Jo Hodges.;Kim M Huffman.;Miriam C Morey.;Shalini Ramasunder.;Herbert Severson.;Courtney Van Houtven.;Lauren M Abbate.;Cynthia J Coffman.
来源: Ann Intern Med. 2021年174卷3期298-307页
Evidence-based models are needed to deliver exercise-related services for knee osteoarthritis efficiently and according to patient needs.
102. Comparison of Knowledge and Information-Seeking Behavior After General COVID-19 Public Health Messages and Messages Tailored for Black and Latinx Communities : A Randomized Controlled Trial.
作者: Marcella Alsan.;Fatima Cody Stanford.;Abhijit Banerjee.;Emily Breza.;Arun G Chandrasekhar.;Sarah Eichmeyer.;Paul Goldsmith-Pinkham.;Lucy Ogbu-Nwobodo.;Benjamin A Olken.;Carlos Torres.;Anirudh Sankar.;Pierre-Luc Vautrey.;Esther Duflo.
来源: Ann Intern Med. 2021年174卷4期484-492页
The paucity of public health messages that directly address communities of color might contribute to racial and ethnic disparities in knowledge and behavior related to coronavirus disease 2019 (COVID-19).
103. Hydroxychloroquine as Postexposure Prophylaxis to Prevent Severe Acute Respiratory Syndrome Coronavirus 2 Infection : A Randomized Trial.
作者: Ruanne V Barnabas.;Elizabeth R Brown.;Anna Bershteyn.;Helen C Stankiewicz Karita.;Christine Johnston.;Lorna E Thorpe.;Angelica Kottkamp.;Kathleen M Neuzil.;Miriam K Laufer.;Meagan Deming.;Michael K Paasche-Orlow.;Patricia J Kissinger.;Alfred Luk.;Kristopher Paolino.;Raphael J Landovitz.;Risa Hoffman.;Torin T Schaafsma.;Meighan L Krows.;Katherine K Thomas.;Susan Morrison.;Harald S Haugen.;Lara Kidoguchi.;Mark Wener.;Alexander L Greninger.;Meei-Li Huang.;Keith R Jerome.;Anna Wald.;Connie Celum.;Helen Y Chu.;Jared M Baeten.; .
来源: Ann Intern Med. 2021年174卷3期344-352页
Effective prevention against coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently limited to nonpharmaceutical strategies. Laboratory and observational data suggested that hydroxychloroquine had biological activity against SARS-CoV-2, potentially permitting its use for prevention.
104. The Effects of Four Doses of Vitamin D Supplements on Falls in Older Adults : A Response-Adaptive, Randomized Clinical Trial.
作者: Lawrence J Appel.;Erin D Michos.;Christine M Mitchell.;Amanda L Blackford.;Alice L Sternberg.;Edgar R Miller.;Stephen P Juraschek.;Jennifer A Schrack.;Sarah L Szanton.;Jeanne Charleston.;Melissa Minotti.;Sheriza N Baksh.;Robert H Christenson.;Josef Coresh.;Lea T Drye.;Jack M Guralnik.;Rita R Kalyani.;Timothy B Plante.;David M Shade.;David L Roth.;James Tonascia.; .
来源: Ann Intern Med. 2021年174卷2期145-156页
Vitamin D supplementation may prevent falls in older persons, but evidence is inconsistent, possibly because of dosage differences.
105. Effectiveness of Adding a Mask Recommendation to Other Public Health Measures to Prevent SARS-CoV-2 Infection in Danish Mask Wearers : A Randomized Controlled Trial.
作者: Henning Bundgaard.;Johan Skov Bundgaard.;Daniel Emil Tadeusz Raaschou-Pedersen.;Christian von Buchwald.;Tobias Todsen.;Jakob Boesgaard Norsk.;Mia M Pries-Heje.;Christoffer Rasmus Vissing.;Pernille B Nielsen.;Ulrik C Winsløw.;Kamille Fogh.;Rasmus Hasselbalch.;Jonas H Kristensen.;Anna Ringgaard.;Mikkel Porsborg Andersen.;Nicole Bakkegård Goecke.;Ramona Trebbien.;Kerstin Skovgaard.;Thomas Benfield.;Henrik Ullum.;Christian Torp-Pedersen.;Kasper Iversen.
来源: Ann Intern Med. 2021年174卷3期335-343页
Observational evidence suggests that mask wearing mitigates transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is uncertain if this observed association arises through protection of uninfected wearers (protective effect), via reduced transmission from infected mask wearers (source control), or both.
106. Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases : A Randomized Trial.
作者: Davit L Aghayan.;Airazat M Kazaryan.;Vegar Johansen Dagenborg.;Bård I Røsok.;Morten Wang Fagerland.;Gudrun Maria Waaler Bjørnelv.;Ronny Kristiansen.;Kjersti Flatmark.;Åsmund Avdem Fretland.;Bjørn Edwin.; .
来源: Ann Intern Med. 2021年174卷2期175-182页
Despite the recent worldwide dissemination of laparoscopic liver surgery, no high-level evidence supports the oncologic safety of this approach.
107. Linked Color Imaging Focused on Neoplasm Detection in the Upper Gastrointestinal Tract : A Randomized Trial.
作者: Shoko Ono.;Kenro Kawada.;Osamu Dohi.;Shinji Kitamura.;Tomoyuki Koike.;Shinichiro Hori.;Hiromitsu Kanzaki.;Takahisa Murao.;Nobuaki Yagi.;Fumisato Sasaki.;Keiichi Hashiguchi.;Shiro Oka.;Kazuhiro Katada.;Ryo Shimoda.;Kazuhiro Mizukami.;Mitsuhiko Suehiro.;Toshihisa Takeuchi.;Shinichi Katsuki.;Momoko Tsuda.;Yuji Naito.;Tatsuyuki Kawano.;Ken Haruma.;Hideki Ishikawa.;Keita Mori.;Mototsugu Kato.; .
来源: Ann Intern Med. 2021年174卷1期18-24页
Linked color imaging (LCI) is a new image-enhanced endoscopy technique that allows users to recognize slight differences in mucosal color.
108. Physical Therapy Referral From Primary Care for Acute Back Pain With Sciatica : A Randomized Controlled Trial.
作者: Julie M Fritz.;Elizabeth Lane.;Molly McFadden.;Gerard Brennan.;John S Magel.;Anne Thackeray.;Kate Minick.;Whitney Meier.;Tom Greene.
来源: Ann Intern Med. 2021年174卷1期8-17页
Few studies have examined primary care management for acute sciatica, including referral to physical therapy.
109. Characteristics of COVID-19 in Homeless Shelters : A Community-Based Surveillance Study.
作者: Julia H Rogers.;Amy C Link.;Denise McCulloch.;Elisabeth Brandstetter.;Kira L Newman.;Michael L Jackson.;James P Hughes.;Janet A Englund.;Michael Boeckh.;Nancy Sugg.;Misja Ilcisin.;Thomas R Sibley.;Kairsten Fay.;Jover Lee.;Peter Han.;Melissa Truong.;Matthew Richardson.;Deborah A Nickerson.;Lea M Starita.;Trevor Bedford.;Helen Y Chu.; .
来源: Ann Intern Med. 2021年174卷1期42-49页
Homeless shelters are a high-risk setting for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission because of crowding and shared hygiene facilities.
110. Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion-Synovitis of Knee Osteoarthritis : A Randomized Trial.
作者: Zhiqiang Wang.;Graeme Jones.;Tania Winzenberg.;Guoqi Cai.;Laura L Laslett.;Dawn Aitken.;Ingrid Hopper.;Ambrish Singh.;Robert Jones.;Jurgen Fripp.;Changhai Ding.;Benny Antony.
来源: Ann Intern Med. 2020年173卷11期861-869页
Current pharmacologic therapies for patients with osteoarthritis are suboptimal.
111. Three-Year Outcomes of Bariatric Surgery in Patients With Obesity and Hypertension : A Randomized Clinical Trial.
作者: Carlos A Schiavon.;Deepak L Bhatt.;Dimas Ikeoka.;Eliana V Santucci.;Renato Nakagawa Santos.;Lucas P Damiani.;Juliana D Oliveira.;Rachel Helena V Machado.;Helio Halpern.;Frederico L J Monteiro.;Patricia M Noujaim.;Ricardo V Cohen.;Marcio G de Souza.;Celso Amodeo.;Luiz A Bortolotto.;Otavio Berwanger.;Alexandre B Cavalcanti.;Luciano F Drager.
来源: Ann Intern Med. 2020年173卷9期685-693页
Midterm effects of bariatric surgery on patients with obesity and hypertension remain uncertain.
112. Effects of Interleukin-1β Inhibition on Incident Hip and Knee Replacement : Exploratory Analyses From a Randomized, Double-Blind, Placebo-Controlled Trial.
作者: Matthias Schieker.;Philip G Conaghan.;Linda Mindeholm.;Jens Praestgaard.;Daniel H Solomon.;Celeste Scotti.;Herman Gram.;Tom Thuren.;Ronenn Roubenoff.;Paul M Ridker.
来源: Ann Intern Med. 2020年173卷7期509-515页
Osteoarthritis is a common inflammatory disorder with no disease-modifying therapies. Whether inhibition of interleukin-1β (IL-1β) can reduce the consequences of large joint osteoarthritis is unclear.
113. Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes : Results From a Randomized Trial.
作者: Maurizio Menichelli.;Franz-Josef Neumann.;Gjin Ndrepepa.;Katharina Mayer.;Jochen Wöhrle.;Isabell Bernlochner.;Gert Richardt.;Bernhard Witzenbichler.;Dirk Sibbing.;Senta Gewalt.;Dominick J Angiolillo.;Shqipdona Lahu.;Christian W Hamm.;Alexander Hapfelmeier.;Dietmar Trenk.;Karl-Ludwig Laugwitz.;Heribert Schunkert.;Stefanie Schüpke.;Adnan Kastrati.
来源: Ann Intern Med. 2020年173卷6期436-444页
The efficacy and safety of a reduced dose of prasugrel versus a standard dose of ticagrelor in elderly patients or those with a low body weight presenting with an acute coronary syndrome (ACS) are unknown.
114. Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19 : A Randomized Trial.
作者: Caleb P Skipper.;Katelyn A Pastick.;Nicole W Engen.;Ananta S Bangdiwala.;Mahsa Abassi.;Sarah M Lofgren.;Darlisha A Williams.;Elizabeth C Okafor.;Matthew F Pullen.;Melanie R Nicol.;Alanna A Nascene.;Kathy H Hullsiek.;Matthew P Cheng.;Darlette Luke.;Sylvain A Lother.;Lauren J MacKenzie.;Glen Drobot.;Lauren E Kelly.;Ilan S Schwartz.;Ryan Zarychanski.;Emily G McDonald.;Todd C Lee.;Radha Rajasingham.;David R Boulware.
来源: Ann Intern Med. 2020年173卷8期623-631页
No effective oral therapy exists for early coronavirus disease 2019 (COVID-19).
115. Health System Costs of Treating Latent Tuberculosis Infection With Four Months of Rifampin Versus Nine Months of Isoniazid in Different Settings.
作者: Mayara Lisboa Bastos.;Jonathon R Campbell.;Olivia Oxlade.;Menonli Adjobimey.;Anete Trajman.;Rovina Ruslami.;Hee Jin Kim.;Joseph Obeng Baah.;Brett G Toelle.;Richard Long.;Vernon Hoeppner.;Kevin Elwood.;Hamdan Al-Jahdali.;Lika Apriani.;Andrea Benedetti.;Kevin Schwartzman.;Dick Menzies.
来源: Ann Intern Med. 2020年173卷3期169-178页
Four months of rifampin treatment for latent tuberculosis infection is safer, has superior treatment completion rates, and is as effective as 9 months of isoniazid. However, daily medication costs are higher for a 4-month rifampin regimen than a 9-month isoniazid regimen.
116. Long-Term Rituximab Use to Maintain Remission of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Randomized Trial.
作者: Pierre Charles.;Élodie Perrodeau.;Maxime Samson.;Bernard Bonnotte.;Antoine Néel.;Christian Agard.;Antoine Huart.;Alexandre Karras.;François Lifermann.;Pascal Godmer.;Pascal Cohen.;Catherine Hanrotel-Saliou.;Nicolas Martin-Silva.;Grégory Pugnet.;François Maurier.;Jean Sibilia.;Pierre-Louis Carron.;Pierre Gobert.;Nadine Meaux-Ruault.;Thomas Le Gallou.;Stéphane Vinzio.;Jean-François Viallard.;Eric Hachulla.;Christine Vinter.;Xavier Puéchal.;Benjamin Terrier.;Philippe Ravaud.;Luc Mouthon.;Loïc Guillevin.; .
来源: Ann Intern Med. 2020年173卷3期179-187页
Biannual rituximab infusions over 18 months effectively maintain remission after a "standard" remission induction regimen for patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV).
117. Effect of Acupuncture for Postprandial Distress Syndrome: A Randomized Clinical Trial.
作者: Jing-Wen Yang.;Li-Qiong Wang.;Xuan Zou.;Shi-Yan Yan.;Yu Wang.;Jing-Jie Zhao.;Jian-Feng Tu.;Jun Wang.;Guang-Xia Shi.;Hui Hu.;Wei Zhou.;Yi Du.;Cun-Zhi Liu.
来源: Ann Intern Med. 2020年172卷12期777-785页
Postprandial distress syndrome (PDS) is the most common subtype of functional dyspepsia. Acupuncture is commonly used to treat PDS, but its effect is uncertain because of the poor quality of prior studies.
118. Rifabutin-Based Triple Therapy (RHB-105) for Helicobacter pylori Eradication: A Double-Blind, Randomized, Controlled Trial.
作者: David Y Graham.;Yamil Canaan.;James Maher.;Gregory Wiener.;Kristina G Hulten.;Ira N Kalfus.
来源: Ann Intern Med. 2020年172卷12期795-802页
Although consensus supports eradication of Helicobacter pylori infections, antimicrobial resistance has substantially reduced eradication rates with most current therapies.
119. L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial.
作者: Maria de Montmollin.;Martin Feller.;Shanthi Beglinger.;Alex McConnachie.;Drahomir Aujesky.;Tinh-Hai Collet.;Ian Ford.;Jacobijn Gussekloo.;Patricia M Kearney.;Vera J C McCarthy.;Simon Mooijaart.;Rosalinde K E Poortvliet.;Terence Quinn.;David J Stott.;Torquil Watt.;Rudi Westendorp.;Nicolas Rodondi.;Douglas C Bauer.
来源: Ann Intern Med. 2020年172卷11期709-716页
L-thyroxine does not improve hypothyroid symptoms among adults with subclinical hypothyroidism (SCH). However, those with greater symptom burden before treatment may still benefit.
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