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1101. In IBS, a smartphone application for self-managing a FODMAP-lowering diet vs. otilonium bromide reduced symptoms at 8 wk.
Carbone F, Van den Houte K, Besard L, et al. Diet or medication in primary care patients with IBS: the DOMINO study-a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Research Institute. Gut. 2022. [Epub ahead of print]. 35483886.
1102. Reduced dietary sodium did not reduce clinical events in heart failure.
Ezekowitz JA, Colin-Ramirez E, Ross H, et al. Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial. Lancet. 2022;399:1391-400. 35381194.
1103. Evaluating the Performance of Centers for Disease Control and Prevention COVID-19 Community Levels as Leading Indicators of COVID-19 Mortality.
Centers for Disease Control and Prevention (CDC) defines low, medium, and high "COVID-19 community levels" to guide interventions, but associated mortality rates have not been reported.
1104. Recommendations for use of ezetimibe and/or PCSK9 inhibitors in patients with elevated LDL-C.
Hao Q, Aertgeerts B, Guyatt G, et al. PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations. BMJ. 2022;377:e069066. 35508320.
1105. In diabetes, some statins reduce non-HDL-C better than others vs. placebo.
Hodkinson A, Tsimpida D, Kontopantelis E, et al. Comparative effectiveness of statins on non-high density lipoprotein cholesterol in people with diabetes and at risk of cardiovascular disease: systematic review and network meta-analysis. BMJ. 2022;376:e067731. 35331984.
1106. Telehealth Strategies for the Delivery of Maternal Health Care : A Rapid Review.
作者: Amy G Cantor.;Rebecca M Jungbauer.;Annette M Totten.;Ellen L Tilden.;Rebecca Holmes.;Azrah Ahmed.;Jesse Wagner.;Amy C Hermesch.;Marian S McDonagh.
来源: Ann Intern Med. 2022年175卷9期1285-1297页
Telehealth strategies to supplement or replace in-person maternity care may affect maternal health outcomes.
1107. Associations of Atrial Fibrillation After Noncardiac Surgery With Stroke, Subsequent Arrhythmia, and Death : A Cohort Study.
作者: Konstantinos C Siontis.;Bernard J Gersh.;Susan A Weston.;Ruoxiang Jiang.;Véronique L Roger.;Peter A Noseworthy.;Alanna M Chamberlain.
来源: Ann Intern Med. 2022年175卷8期1065-1072页
Postoperative atrial fibrillation (AF) after noncardiac surgery confers increased risks for ischemic stroke and transient ischemic attack (TIA). How outcomes for postoperative AF after noncardiac surgery compare with those for AF occurring outside of the operative setting is unknown.
1108. Ethical Considerations in Precision Medicine and Genetic Testing in Internal Medicine Practice: A Position Paper From the American College of Physicians.
作者: Lisa Soleymani Lehmann.;Lois Snyder Sulmasy.;Wylie Burke.; .
来源: Ann Intern Med. 2022年175卷9期1322-1323页
This American College of Physicians position paper aims to inform ethical decision making for the integration of precision medicine and genetic testing into clinical care. Although the positions are primarily intended for practicing physicians, they may apply to other health care professionals and can also inform how health care systems, professional schools, and residency programs integrate genomics into educational and clinical settings. Addressing the challenges of precision medicine and genetic testing will guide ethical and responsible implementation to improve health outcomes.
1109. How the Gender Wage Gap for Primary Care Physicians Differs by Compensation Approach : A Microsimulation Study.
作者: Ishani Ganguli.;Kathleen L Mulligan.;Robert L Phillips.;Sanjay Basu.
来源: Ann Intern Med. 2022年175卷8期1135-1142页
The physician gender wage gap may be due, in part, to productivity-based compensation models that undervalue female practice patterns.
1110. Comparing Racial Differences in Emphysema Prevalence Among Adults With Normal Spirometry: A Secondary Data Analysis of the CARDIA Lung Study.
作者: Gabrielle Y Liu.;Sadiya S Khan.;Laura A Colangelo.;Daniel Meza.;George R Washko.;Peter H S Sporn.;David R Jacobs.;Mark T Dransfield.;Mercedes R Carnethon.;Ravi Kalhan.
来源: Ann Intern Med. 2022年175卷8期1118-1125页
Computed tomography (CT) imaging complements spirometry and may provide insight into racial disparities in respiratory health.
1111. Bipolar Disorder.
Bipolar disorder (BD) affects approximately 2% of U.S. adults and is the most costly mental health condition for commercial insurers nationwide. Rates of BD are elevated among persons with depression, anxiety disorders, and substance use disorders-conditions frequently seen by primary care clinicians. In addition, antidepressants can precipitate manic or hypomanic symptoms or rapid cycling in persons with undiagnosed BD. Thus, screening in these high-risk groups is indicated. Effective treatments exist, and many can be safely and effectively administered by primary care clinicians.
1112. Impact of Hepatitis C Treatment Uptake on Cirrhosis and Mortality in Persons Who Inject Drugs : A Longitudinal, Community-Based Cohort Study.
作者: Javier A Cepeda.;David L Thomas.;Jacqueline Astemborski.;Jacqueline E Rudolph.;Rachel Gicquelais.;Gregory D Kirk.;Shruti H Mehta.
来源: Ann Intern Med. 2022年175卷8期1083-1091页
Hepatitis C virus (HCV) infection can be cured, and the United States has joined the World Health Organization in calling for HCV elimination by 2030. However, historically low uptake of HCV treatment among people who inject drugs (PWID) threatens HCV elimination and exacerbates social and racial health disparities.
1113. Long-Term Services and Supports for Older Adults: A Position Paper From the American College of Physicians.
The number of Americans aged 65 years or older is expected to increase in the coming decades. Because the risk for disability increases with age, more persons will need long-term services and supports (LTSS) to help with bathing, eating, dressing, and other everyday tasks. Long-term services and supports are delivered in nursing homes, assisted living facilities, the person's home, and other settings. However, the LTSS sector faces several challenges, including keeping patients and staff safe during the COVID-19 pandemic, workforce shortages, quality problems, and fragmented coverage options. In this position paper, the American College of Physicians offers policy recommendations on LTSS coverage, financing, workforce, safety and quality, and emergency preparedness and calls on policymakers and other stakeholders to reform and improve the LTSS sector so that care is high quality, accessible, equitable, and affordable.
1114. In AF, CV benefits of catheter ablation vs. medical therapy may vary by age.
Bahnson TD, Giczewska A, Mark DB, et al. Association between age and outcomes of catheter ablation versus medical therapy for atrial fibrillation: results from the CABANA trial. Circulation. 2022;145:796-804. 34933570.
1115. Effect of Social Needs Case Management on Hospital Use Among Adult Medicaid Beneficiaries : A Randomized Study.
作者: Daniel M Brown.;Elizabeth A Hernandez.;Sara Levin.;Mathijs De Vaan.;Mi-Ok Kim.;Chris Lynch.;Anna Roth.;Amanda L Brewster.
来源: Ann Intern Med. 2022年175卷8期1109-1117页
Case management programs assisting patients with social needs may improve health and avoid unnecessary health care use, but little is known about their effectiveness.
1116. ACG-CAG provided suggestions for periendoscopic management of anticoagulants and antiplatelets.
Abraham NS, Barkun AN, Sauer BG, et al. American College of Gastroenterology-Canadian Association of Gastroenterology clinical practice guideline: management of anticoagulants and antiplatelets during acute gastrointestinal bleeding and the periendoscopic period. Am J Gastroenterol. 2022;117:542-58. 35297395.
1117. In women with stress UI, device-guided pelvic floor muscle training safely improved symptoms more than self-guided training.
Weinstein MM, Dunivan G, Guaderrama NM, et al. Digital therapeutic device for urinary incontinence: a randomized controlled trial. Obstet Gynecol. 2022;139:606-15. 35271539.
1118. ESCMID recommendations for COVID-19 testing in asymptomatic persons to prevent transmission in health care.
Carrara E, Ong DS, Hussein K, et al. ESCMID guidelines on testing for SARS-CoV-2 in asymptomatic individuals to prevent transmission in the health care setting. Clin Microbiol Infect. 2022;28:672-80. 35124258.
1119. In critically ill patients with COVID-19, antiplatelet therapy did not increase organ support-free days at 21 d.
REMAP-CAP Writing Committee for the REMAP-CAP Investigators. Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19: a randomized clinical trial. JAMA. 2022;327:1247-59. 35315874.
1120. In former smokers with COPD, HEPA and carbon filter air cleaners improved moderate exacerbations but not QoL.
Hansel NN, Putcha N, Woo H, et al. Randomized clinical trial of air cleaners to improve indoor air quality and chronic obstructive pulmonary disease health: results of the CLEAN AIR study. Am J Respir Crit Care Med. 2022;205:421-30. 34449285.
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