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1001. Factors Associated With Recurrent Pediatric Firearm Injury : A 10-Year Retrospective Cohort Analysis.
作者: Zoe M Miller.;Benjamin P Cooper.;Daphne Lew.;Rachel M Ancona.;Vicki Moran.;Christopher Behr.;Marguerite W Spruce.;Lindsay M Kranker.;Michael A Mancini.;Matt Vogel.;Doug J E Schuerer.;Lindsay Clukies.;Megan L Ranney.;Randi E Foraker.;Kristen L Mueller.
来源: Ann Intern Med. 2024年177卷10期1381-1388页
Firearm injuries are the leading cause of death among children aged 0 to 17 years in the United States.
1003. Hormonal Treatments and Vaginal Moisturizers for Genitourinary Syndrome of Menopause : A Systematic Review.
作者: Elisheva R Danan.;Catherine Sowerby.;Kristen E Ullman.;Kristine Ensrud.;Mary L Forte.;Nicholas Zerzan.;Maylen Anthony.;Caleb Kalinowski.;Hamdi I Abdi.;Jessica K Friedman.;Adrienne Landsteiner.;Nancy Greer.;Rahel Nardos.;Cynthia Fok.;Philipp Dahm.;Mary Butler.;Timothy J Wilt.;Susan Diem.
来源: Ann Intern Med. 2024年177卷10期1400-1414页
Postmenopausal women commonly experience vulvovaginal, urinary, and sexual symptoms associated with genitourinary syndrome of menopause (GSM).
1004. Knee Osteoarthritis.
Knee osteoarthritis (OA) typically presents with joint pain that is exacerbated by use and alleviated with rest. There is relatively brief, self-limited morning stiffness and absence of constitutional symptoms. Overweight and obesity are the most important modifiable risk factors. Although pharmacologic and nonpharmacologic interventions are generally effective at alleviating pain and improving physical function, they do not fundamentally reverse the pathologic and radiographic process of knee OA. As the severity of disease increases, the magnitude of pain and functional impairment intensifies. Surgical intervention should be pursued to relieve pain and restore functionality only when nonpharmacologic approaches and pharmacologic agents fail to control pain.
1005. Complementary and Alternative Therapies for Genitourinary Syndrome of Menopause : An Evidence Map.
作者: Kristen E Ullman.;Susan Diem.;Mary L Forte.;Kristine Ensrud.;Catherine Sowerby.;Nicholas Zerzan.;Maylen Anthony.;Adrienne Landsteiner.;Nancy Greer.;Mary Butler.;Timothy J Wilt.;Elisheva R Danan.
来源: Ann Intern Med. 2024年177卷10期1389-1399页
Women seeking nonhormonal interventions for vulvovaginal, urinary, and sexual symptoms associated with genitourinary syndrome of menopause (GSM) may seek out complementary and alternative medicine or therapies (CAMs).
1008. Guidelines Recommending That Clinicians Advise Patients on Lifestyle Changes: A Popular but Questionable Approach to Improve Public Health.
作者: Minna Johansson.;Amanda Niklasson.;Loai Albarqouni.;Karsten Juhl Jørgensen.;Gordon Guyatt.;Victor M Montori.
来源: Ann Intern Med. 2024年177卷10期1425-1427页 1011. Association Between Hospital Type and Resilience During COVID-19 Caseload Stress : A Retrospective Cohort Study.
作者: Maniraj Neupane.;Sarah Warner.;Alex Mancera.;Junfeng Sun.;Christina Yek.;Sadia H Sarzynski.;Roxana Amirahmadi.;Mary Richert.;Emad Chishti.;Morgan Walker.;Bruce J Swihart.;Steven H Mitchell.;John Hick.;Bram Rochwerg.;Eddy Fan.;Cumhur Y Demirkale.;Sameer S Kadri.
来源: Ann Intern Med. 2024年177卷10期1370-1380页
Imbalances between hospital caseload and care resources that strained U.S. hospitals during the pandemic have persisted after the pandemic amid ongoing staff shortages. Understanding which hospital types were more resilient to pandemic overcrowding-related excess deaths may prioritize patient safety during future crises.
1012. After ACS, telemedicine-based care with remote patient monitoring vs. usual care reduced hospital readmissions at 6 mo.
Alshahrani NS, Hartley A, Howard J, et al. Randomized trial of remote assessment of patients after an acute coronary syndrome. J Am Coll Cardiol. 2024;83:2250-2259. 38588928.
1013. A next-generation mt-sDNA test had 94% sensitivity for colorectal cancer and 91% specificity for advanced neoplasia.
Imperiale TF, Porter K, Zella J, et al; BLUE-C Study Investigators. Next-generation multitarget stool DNA test for colorectal cancer screening. N Engl J Med. 2024;390:984-993. 38477986.
1014. In early Parkinson disease, daily subcutaneous lixisenatide reduced motor disability progression at 12 mo.
Meissner WG, Remy P, Giordana C, et al; LIXIPARK Study Group. Trial of lixisenatide in early Parkinson's disease. N Engl J Med. 2024;390:1176-1185. 38598572.
1015. Comparative Performance of Common Fecal Immunochemical Tests : A Cross-Sectional Study.
作者: Barcey T Levy.;Yinghui Xu.;Jeanette M Daly.;Richard M Hoffman.;Jeffrey D Dawson.;Navkiran K Shokar.;Marc J Zuckerman.;Jennifer Molokwu.;Daniel S Reuland.;Seth D Crockett.
来源: Ann Intern Med. 2024年177卷10期1350-1360页
Despite widespread use of fecal immunochemical tests (FITs) for colorectal cancer (CRC) screening, data to guide test selection are limited.
1016. In factor Xa inhibitor-related acute ICH, andexanet vs. usual care improved hemostatic efficacy but increased thrombotic events.
Connolly SJ, Sharma M, Cohen AT, et al; ANNEXA-I Investigators. Andexanet for factor Xa inhibitor-associated acute intracerebral hemorrhage. N Engl J Med. 2024;390:1745-1755. 38749032.
1017. Time From Approval to Reimbursement of New Drugs: A Comparative Analysis Between the United States, England, Germany, France, and Switzerland (2011-2022).
作者: Camille E G Glaus.;Miquel Serra-Burriel.;Stacie B Dusetzina.;Kerstin N Vokinger.
来源: Ann Intern Med. 2024年177卷10期1442-1444页 1018. In acute ischemic stroke with a large core infarct, endovascular thrombectomy reduced disability at 90 d.
Costalat V, Jovin TG, Albucher JF, et al; LASTE Trial Investigators. Trial of thrombectomy for stroke with a large infarct of unrestricted size. N Engl J Med. 2024;390:1677-1689. 38718358.
1019. In T2DM with CKD, semaglutide reduced major kidney disease events at 3 y.
Perkovic V, Tuttle KR, Rossing P, et al; FLOW Trial Committees and Investigators. Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes. N Engl J Med. 2024;391:109-121. 38785209.
1020. In sepsis or septic shock, prolonged vs. intermittent infusion of β-lactam antibiotics reduces mortality at 90 d.
Abdul-Aziz MH, Hammond NE, Brett SJ, et al. Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis. JAMA. 12 June 2024. [Epub ahead of print.] 38864162.
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