81. Inhaled Reliever Therapies for Asthma: A Systematic Review and Meta-Analysis.
作者: Daniel G Rayner.;Dario M Ferri.;Gordon H Guyatt.;Paul M O'Byrne.;Romina Brignardello-Petersen.;Farid Foroutan.;Bradley Chipps.;Kaharu Sumino.;Tamara T Perry.;Sharmilee Nyenhuis.;John Oppenheimer.;Elliot Israel.;Flavia Hoyte.;Katherine Rivera-Spoljaric.;Ellen McCabe.;Susana Rangel.;Lindsay E Shade.;Valerie G Press.;Lisa Hall.;Dia Sue-Wah-Sing.;Angel Melendez.;Hilarry Orr.;Tonya Winders.;Donna D Gardner.;Kathyrn Przywara.;Matthew A Rank.;Leonard B Bacharier.;Giselle Mosnaim.;Derek K Chu.
来源: JAMA. 2025年333卷2期143-152页
The optimal inhaled reliever therapy for asthma remains unclear.
82. Early, Individualized Recommendations for Hospitalized Patients With Acute Kidney Injury: A Randomized Clinical Trial.
作者: Abinet M Aklilu.;Steven Menez.;Megan L Baker.;Dannielle Brown.;Katie K Dircksen.;Kisha A Dunkley.;Simon Correa Gaviria.;Salia Farrokh.;Sophia C Faulkner.;Charles Jones.;Bashar A Kadhim.;Dustin Le.;Fan Li.;Amrita Makhijani.;Melissa Martin.;Dennis G Moledina.;Claudia Coronel-Moreno.;Kyle D O'Connor.;Kyra Shelton.;Kristina Shvets.;Nityasree Srialluri.;Jia Wei Tan.;Jeffrey M Testani.;Celia P Corona-Villalobos.;Yu Yamamoto.;Chirag R Parikh.;F Perry Wilson.; .
来源: JAMA. 2024年332卷24期2081-2090页
Acute kidney injury (AKI) is a common complication during hospitalization and is associated with adverse outcomes.
83. Expanded Newborn Screening Using Genome Sequencing for Early Actionable Conditions.
作者: Alban Ziegler.;Carrie Koval-Burt.;Denise M Kay.;Sharon F Suchy.;Amber Begtrup.;Katherine G Langley.;Rebecca Hernan.;Laura M Amendola.;Brenna M Boyd.;Jennifer Bradley.;Tracy Brandt.;Lilian L Cohen.;Alison J Coffey.;Joseph M Devaney.;Beata Dygulska.;Bethany Friedman.;Ramsay L Fuleihan.;Awura Gyimah.;Sihoun Hahn.;Sean Hofherr.;Kathleen S Hruska.;Zhanzhi Hu.;Médéric Jeanne.;Guanjun Jin.;D Aaron Johnson.;Haluk Kavus.;Rudolph L Leibel.;Steven J Lobritto.;Stephen McGee.;Joshua D Milner.;Kirsty McWalter.;Kristin G Monaghan.;Jordan S Orange.;Nicole Pimentel Soler.;Yeyson Quevedo.;Samantha Ratner.;Kyle Retterer.;Ankur Shah.;Natasha Shapiro.;Robert J Sicko.;Eric S Silver.;Samuel Strom.;Rebecca I Torene.;Olatundun Williams.;Vincent D Ustach.;Julia Wynn.;Ryan J Taft.;Paul Kruszka.;Michele Caggana.;Wendy K Chung.
来源: JAMA. 2025年333卷3期232-240页
The feasibility of implementing genome sequencing as an adjunct to traditional newborn screening (NBS) in newborns of different racial and ethnic groups is not well understood.
85. Dialysis Facility Staffing Ratios and Kidney Transplant Access Among Adolescents and Young Adults.
作者: Alexandra C Bicki.;Barbara Grimes.;Charles E McCulloch.;Timothy P Copeland.;Elaine Ku.
来源: JAMA. 2024年332卷23期2003-2013页
Patient to staff ratios vary across US dialysis facilities and have been associated with patient outcomes in older adults.
86. Three vs 6 Cycles of Chemotherapy for High-Risk Retinoblastoma: A Randomized Clinical Trial.
作者: Huijing Ye.;Kang Xue.;Ping Zhang.;Rongxin Chen.;Xiaowen Zhai.;Li Ling.;Wei Xiao.;Lijuan Tang.;Hongsheng Wang.;Yuxiang Mao.;Siming Ai.;Yingwen Bi.;Qing Liu.;Yusha Zou.;Jiang Qian.;Huasheng Yang.
来源: JAMA. 2024年332卷19期1634-1641页
Adjuvant therapy is an important and effective treatment for retinoblastoma. However, there is a lack of head-to-head clinical trials comparing 3 vs 6 cycles of CEV chemotherapy (carboplatin, etoposide, and vincristine) for enucleated unilateral retinoblastoma with high-risk pathological features.
88. Effect of Electric Fans on Body Core Temperature in Older Adults Exposed to Extreme Indoor Heat.
作者: Fergus K O'Connor.;Robert D Meade.;Katie E Wagar.;Roberto C Harris-Mostert.;Emily J Tetzlaff.;James J McCormick.;Glen P Kenny.
来源: JAMA. 2024年332卷20期1752-1754页 90. Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder.
作者: Bohdan Nosyk.;Jeong Eun Min.;Fahmida Homayra.;Megan Kurz.;Brenda Carolina Guerra-Alejos.;Ruyu Yan.;Micah Piske.;Shaun R Seaman.;Paxton Bach.;Sander Greenland.;Mohammad Ehsanul Karim.;Uwe Siebert.;Julie Bruneau.;Paul Gustafson.;Kyle Kampman.;P Todd Korthuis.;Thomas Loughin.;Lawrence C McCandless.;Robert W Platt.;Kevin T Schnepel.;M Eugenia Socías.
来源: JAMA. 2024年332卷21期1822-1831页
Previous studies on the comparative effectiveness between buprenorphine and methadone provided limited evidence on differences in treatment effects across key subgroups and were drawn from populations who use primarily heroin or prescription opioids, although fentanyl use is increasing across North America.
92. Testing and Evaluation of Health Care Applications of Large Language Models: A Systematic Review.
作者: Suhana Bedi.;Yutong Liu.;Lucy Orr-Ewing.;Dev Dash.;Sanmi Koyejo.;Alison Callahan.;Jason A Fries.;Michael Wornow.;Akshay Swaminathan.;Lisa Soleymani Lehmann.;Hyo Jung Hong.;Mehr Kashyap.;Akash R Chaurasia.;Nirav R Shah.;Karandeep Singh.;Troy Tazbaz.;Arnold Milstein.;Michael A Pfeffer.;Nigam H Shah.
来源: JAMA. 2025年333卷4期319-328页
Large language models (LLMs) can assist in various health care activities, but current evaluation approaches may not adequately identify the most useful application areas.
98. Electronic Nudges to Increase Influenza Vaccination in Patients With Chronic Diseases: A Randomized Clinical Trial.
作者: Niklas Dyrby Johansen.;Muthiah Vaduganathan.;Ankeet S Bhatt.;Daniel Modin.;Safia Chatur.;Brian L Claggett.;Kira Hyldekær Janstrup.;Carsten Schade Larsen.;Lykke Larsen.;Lothar Wiese.;Michael Dalager-Pedersen.;Lars Køber.;Scott D Solomon.;Pradeesh Sivapalan.;Jens Ulrik Stæhr Jensen.;Cyril Jean-Marie Martel.;Tyra Grove Krause.;Tor Biering-Sørensen.
来源: JAMA. 2024年332卷22期1900-1911页
Despite strong worldwide guideline recommendations, influenza vaccination rates remain suboptimal among young and middle-aged patients with chronic diseases. Effective scalable strategies to increase vaccination are needed.
99. Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients: The TELESCOPE Randomized Clinical Trial.
作者: Adriano J Pereira.;Danilo T Noritomi.;Maura Cristina Dos Santos.;Thiago D Corrêa.;Leonardo J R Ferraz.;Guilherme P P Schettino.;Eduardo Cordioli.;Renata A Morbeck.;Lúbia C Morais.;Jorge I F Salluh.;Luciano C P Azevedo.;Rodrigo S Biondi.;Regis G Rosa.;Alexandre B Cavalcanti.;Otavio Berwanger.;Ary Serpa Neto.;Otavio T Ranzani.
来源: JAMA. 2024年332卷21期1798-1807页
Despite its implementation in several countries, there has not been a randomized clinical trial to assess whether telemedicine in intensive care units (ICUs) could improve clinical outcomes of critically ill patients.
100. Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury: The TRAIN Randomized Clinical Trial.
作者: Fabio Silvio Taccone.;Carla Bittencourt Rynkowski.;Kirsten Møller.;Piet Lormans.;Manuel Quintana-Díaz.;Anselmo Caricato.;Marco Antonio Cardoso Ferreira.;Rafael Badenes.;Pedro Kurtz.;Christian Baastrup Søndergaard.;Kirsten Colpaert.;Leticia Petterson.;Herve Quintard.;Raphael Cinotti.;Elisa Gouvêa Bogossian.;Cassia Righy.;Serena Silva.;Erik Roman-Pognuz.;Catherine Vandewaeter.;Daniel Lemke.;Olivier Huet.;Ata Mahmoodpoor.;Aaron Blandino Ortiz.;Mathieu van der Jagt.;Russell Chabanne.;Walter Videtta.;Pierre Bouzat.;Jean-Louis Vincent.; .
来源: JAMA. 2024年332卷19期1623-1633页
Blood transfusions are commonly administered to patients with acute brain injury. The optimal hemoglobin transfusion threshold is uncertain in this patient population.
|