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81. Association Between Palliative Care and Patient and Caregiver Outcomes: A Systematic Review and Meta-analysis.
作者: Dio Kavalieratos.;Jennifer Corbelli.;Di Zhang.;J Nicholas Dionne-Odom.;Natalie C Ernecoff.;Janel Hanmer.;Zachariah P Hoydich.;Dara Z Ikejiani.;Michele Klein-Fedyshin.;Camilla Zimmermann.;Sally C Morton.;Robert M Arnold.;Lucas Heller.;Yael Schenker.
来源: JAMA. 2016年316卷20期2104-2114页
The use of palliative care programs and the number of trials assessing their effectiveness have increased.
82. Prevalence and Prognostic Implications of Coronary Artery Calcification in Low-Risk Women: A Meta-analysis.
作者: Maryam Kavousi.;Chintan S Desai.;Colby Ayers.;Roger S Blumenthal.;Matthew J Budoff.;Amir-Abbas Mahabadi.;M Arfan Ikram.;Aad van der Lugt.;Albert Hofman.;Raimund Erbel.;Amit Khera.;Marie H Geisel.;Karl-Heinz Jöckel.;Nils Lehmann.;Udo Hoffmann.;Christopher J O'Donnell.;Joseph M Massaro.;Kiang Liu.;Stefan Möhlenkamp.;Hongyan Ning.;Oscar H Franco.;Philip Greenland.
来源: JAMA. 2016年316卷20期2126-2134页
The role of coronary artery calcium (CAC) testing for guiding preventive strategies among women at low cardiovascular disease (CVD) risk based on the American College of Cardiology and American Heart Association CVD prevention guidelines is unclear.
83. Statins for Prevention of Cardiovascular Disease in Adults: Evidence Report and Systematic Review for the US Preventive Services Task Force.
作者: Roger Chou.;Tracy Dana.;Ian Blazina.;Monica Daeges.;Thomas L Jeanne.
来源: JAMA. 2016年316卷19期2008-2024页
Cardiovascular disease (CVD), the leading cause of mortality and morbidity in the United States, may be potentially preventable with statin therapy.
84. Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis.
作者: Luca A Lotta.;Stephen J Sharp.;Stephen Burgess.;John R B Perry.;Isobel D Stewart.;Sara M Willems.;Jian'an Luan.;Eva Ardanaz.;Larraitz Arriola.;Beverley Balkau.;Heiner Boeing.;Panos Deloukas.;Nita G Forouhi.;Paul W Franks.;Sara Grioni.;Rudolf Kaaks.;Timothy J Key.;Carmen Navarro.;Peter M Nilsson.;Kim Overvad.;Domenico Palli.;Salvatore Panico.;Jose-Ramón Quirós.;Elio Riboli.;Olov Rolandsson.;Carlotta Sacerdote.;Elena C Salamanca.;Nadia Slimani.;Annemieke Mw Spijkerman.;Anne Tjonneland.;Rosario Tumino.;Daphne L van der A.;Yvonne T van der Schouw.;Mark I McCarthy.;Inês Barroso.;Stephen O'Rahilly.;David B Savage.;Naveed Sattar.;Claudia Langenberg.;Robert A Scott.;Nicholas J Wareham.
来源: JAMA. 2016年316卷13期1383-1391页
Low-density lipoprotein cholesterol (LDL-C)-lowering alleles in or near NPC1L1 or HMGCR, encoding the respective molecular targets of ezetimibe and statins, have previously been used as proxies to study the efficacy of these lipid-lowering drugs. Alleles near HMGCR are associated with a higher risk of type 2 diabetes, similar to the increased incidence of new-onset diabetes associated with statin treatment in randomized clinical trials. It is unknown whether alleles near NPC1L1 are associated with the risk of type 2 diabetes.
85. Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis.
作者: Michael G Silverman.;Brian A Ference.;Kyungah Im.;Stephen D Wiviott.;Robert P Giugliano.;Scott M Grundy.;Eugene Braunwald.;Marc S Sabatine.
来源: JAMA. 2016年316卷12期1289-97页
The comparative clinical benefit of nonstatin therapies that reduce low-density lipoprotein cholesterol (LDL-C) remains uncertain.
86. Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis.
作者: Jeffrey L Saver.;Mayank Goyal.;Aad van der Lugt.;Bijoy K Menon.;Charles B L M Majoie.;Diederik W Dippel.;Bruce C Campbell.;Raul G Nogueira.;Andrew M Demchuk.;Alejandro Tomasello.;Pere Cardona.;Thomas G Devlin.;Donald F Frei.;Richard du Mesnil de Rochemont.;Olvert A Berkhemer.;Tudor G Jovin.;Adnan H Siddiqui.;Wim H van Zwam.;Stephen M Davis.;Carlos Castaño.;Biggya L Sapkota.;Puck S Fransen.;Carlos Molina.;Robert J van Oostenbrugge.;Ángel Chamorro.;Hester Lingsma.;Frank L Silver.;Geoffrey A Donnan.;Ashfaq Shuaib.;Scott Brown.;Bruce Stouch.;Peter J Mitchell.;Antoni Davalos.;Yvo B W E M Roos.;Michael D Hill.; .
来源: JAMA. 2016年316卷12期1279-88页
Endovascular thrombectomy with second-generation devices is beneficial for patients with ischemic stroke due to intracranial large-vessel occlusions. Delineation of the association of treatment time with outcomes would help to guide implementation.
87. Association of Noninvasive Ventilation Strategies With Mortality and Bronchopulmonary Dysplasia Among Preterm Infants: A Systematic Review and Meta-analysis.
Various noninvasive ventilation strategies are used to prevent bronchopulmonary dysplasia (BPD) of preterm infants; however, the best mode is uncertain.
88. Comparison of Clinical Outcomes and Adverse Events Associated With Glucose-Lowering Drugs in Patients With Type 2 Diabetes: A Meta-analysis.
作者: Suetonia C Palmer.;Dimitris Mavridis.;Antonio Nicolucci.;David W Johnson.;Marcello Tonelli.;Jonathan C Craig.;Jasjot Maggo.;Vanessa Gray.;Giorgia De Berardis.;Marinella Ruospo.;Patrizia Natale.;Valeria Saglimbene.;Sunil V Badve.;Yeoungjee Cho.;Annie-Claire Nadeau-Fredette.;Michael Burke.;Labib Faruque.;Anita Lloyd.;Nasreen Ahmad.;Yuanchen Liu.;Sophanny Tiv.;Natasha Wiebe.;Giovanni F M Strippoli.
来源: JAMA. 2016年316卷3期313-24页
Numerous glucose-lowering drugs are used to treat type 2 diabetes.
89. Use of Plant-Based Therapies and Menopausal Symptoms: A Systematic Review and Meta-analysis.
作者: Oscar H Franco.;Rajiv Chowdhury.;Jenna Troup.;Trudy Voortman.;Setor Kunutsor.;Maryam Kavousi.;Clare Oliver-Williams.;Taulant Muka.
来源: JAMA. 2016年315卷23期2554-63页
Between 40% and 50% of women in Western countries use complementary therapies to manage menopausal symptoms.
90. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
作者: Jennifer S Lin.;Margaret A Piper.;Leslie A Perdue.;Carolyn M Rutter.;Elizabeth M Webber.;Elizabeth O'Connor.;Ning Smith.;Evelyn P Whitlock.
来源: JAMA. 2016年315卷23期2576-94页
Colorectal cancer (CRC) remains a significant cause of morbidity and mortality in the United States.
91. Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis.
作者: Rohan Khera.;Mohammad Hassan Murad.;Apoorva K Chandar.;Parambir S Dulai.;Zhen Wang.;Larry J Prokop.;Rohit Loomba.;Michael Camilleri.;Siddharth Singh.
来源: JAMA. 2016年315卷22期2424-34页
Five medications have been approved for the management of obesity, but data on comparative effectiveness are limited.
92. Screening for Impaired Visual Acuity in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
作者: Roger Chou.;Tracy Dana.;Christina Bougatsos.;Sara Grusing.;Ian Blazina.
来源: JAMA. 2016年315卷9期915-33页
Impaired visual acuity is common among older adults and can adversely affect function and quality of life.
93. Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
作者: Manu Shankar-Hari.;Gary S Phillips.;Mitchell L Levy.;Christopher W Seymour.;Vincent X Liu.;Clifford S Deutschman.;Derek C Angus.;Gordon D Rubenfeld.;Mervyn Singer.; .
来源: JAMA. 2016年315卷8期775-87页
Septic shock currently refers to a state of acute circulatory failure associated with infection. Emerging biological insights and reported variation in epidemiology challenge the validity of this definition.
94. Primary Care Screening for and Treatment of Depression in Pregnant and Postpartum Women: Evidence Report and Systematic Review for the US Preventive Services Task Force.
作者: Elizabeth O'Connor.;Rebecca C Rossom.;Michelle Henninger.;Holly C Groom.;Brittany U Burda.
来源: JAMA. 2016年315卷4期388-406页
Depression is a source of substantial burden for individuals and their families, including women during the pregnant and postpartum period.
95. Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis.
作者: Navdeep Tangri.;Morgan E Grams.;Andrew S Levey.;Josef Coresh.;Lawrence J Appel.;Brad C Astor.;Gabriel Chodick.;Allan J Collins.;Ognjenka Djurdjev.;C Raina Elley.;Marie Evans.;Amit X Garg.;Stein I Hallan.;Lesley A Inker.;Sadayoshi Ito.;Sun Ha Jee.;Csaba P Kovesdy.;Florian Kronenberg.;Hiddo J Lambers Heerspink.;Angharad Marks.;Girish N Nadkarni.;Sankar D Navaneethan.;Robert G Nelson.;Stephanie Titze.;Mark J Sarnak.;Benedicte Stengel.;Mark Woodward.;Kunitoshi Iseki.; .
来源: JAMA. 2016年315卷2期164-74页
Identifying patients at risk of chronic kidney disease (CKD) progression may facilitate more optimal nephrology care. Kidney failure risk equations, including such factors as age, sex, estimated glomerular filtration rate, and calcium and phosphate concentrations, were previously developed and validated in 2 Canadian cohorts. Validation in other regions and in CKD populations not under the care of a nephrologist is needed.
96. Mental Health Conditions Among Patients Seeking and Undergoing Bariatric Surgery: A Meta-analysis.
作者: Aaron J Dawes.;Melinda Maggard-Gibbons.;Alicia R Maher.;Marika J Booth.;Isomi Miake-Lye.;Jessica M Beroes.;Paul G Shekelle.
来源: JAMA. 2016年315卷2期150-63页
Bariatric surgery is associated with sustained weight loss and improved physical health status for severely obese individuals. Mental health conditions may be common among patients seeking bariatric surgery; however, the prevalence of these conditions and whether they are associated with postoperative outcomes remains unknown.
97. Prevalence of Depression and Depressive Symptoms Among Resident Physicians: A Systematic Review and Meta-analysis.
作者: Douglas A Mata.;Marco A Ramos.;Narinder Bansal.;Rida Khan.;Constance Guille.;Emanuele Di Angelantonio.;Srijan Sen.
来源: JAMA. 2015年314卷22期2373-83页
Physicians in training are at high risk for depression. However, the estimated prevalence of this disorder varies substantially between studies.
98. CPAP vs Mandibular Advancement Devices and Blood Pressure in Patients With Obstructive Sleep Apnea: A Systematic Review and Meta-analysis.
Obstructive sleep apnea is associated with higher levels of blood pressure (BP), which can lead to increased cardiovascular risk.
99. Endovascular Thrombectomy for Acute Ischemic Stroke: A Meta-analysis.
作者: Jetan H Badhiwala.;Farshad Nassiri.;Waleed Alhazzani.;Magdy H Selim.;Forough Farrokhyar.;Julian Spears.;Abhaya V Kulkarni.;Sheila Singh.;Abdulrahman Alqahtani.;Bram Rochwerg.;Mohammad Alshahrani.;Naresh K Murty.;Adel Alhazzani.;Blake Yarascavitch.;Kesava Reddy.;Osama O Zaidat.;Saleh A Almenawer.
来源: JAMA. 2015年314卷17期1832-43页
Endovascular intervention for acute ischemic stroke improves revascularization. But trials examining endovascular therapy yielded variable functional outcomes, and the effect of endovascular intervention among subgroups needs better definition.
100. Cannabinoids for Medical Use: A Systematic Review and Meta-analysis.
作者: Penny F Whiting.;Robert F Wolff.;Sohan Deshpande.;Marcello Di Nisio.;Steven Duffy.;Adrian V Hernandez.;J Christiaan Keurentjes.;Shona Lang.;Kate Misso.;Steve Ryder.;Simone Schmidlkofer.;Marie Westwood.;Jos Kleijnen.
来源: JAMA. 2015年313卷24期2456-73页
Cannabis and cannabinoid drugs are widely used to treat disease or alleviate symptoms, but their efficacy for specific indications is not clear.
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