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961. Slow response to vancomycin or vancomycin plus rifampin in methicillin-resistant Staphylococcus aureus endocarditis.
To determine the median response time to therapy with vancomycin alone or with vancomycin plus rifampin in patients with methicillin-resistant Staphylococcus aureus (MRSA) endocarditis.
962. Decrease in serum hepatitis C viral RNA during alpha-interferon therapy for chronic hepatitis C.
作者: M Shindo.;A M Di Bisceglie.;L Cheung.;J W Shih.;K Cristiano.;S M Feinstone.;J H Hoofnagle.
来源: Ann Intern Med. 1991年115卷9期700-4页
To assess the effect of alpha-interferon therapy on hepatitis C viral RNA in serum of patients with chronic hepatitis C.
963. Thoracic radiation therapy alone compared with combined chemoradiotherapy for locally unresectable non-small cell lung cancer. A randomized, phase III trial.
作者: R F Morton.;J R Jett.;W L McGinnis.;J D Earle.;T M Therneau.;J E Krook.;T E Elliott.;J A Mailliard.;R A Nelimark.;A W Maksymiuk.
来源: Ann Intern Med. 1991年115卷9期681-6页
To compare the survival of patients with medically inoperable or unresectable stage III non-small cell lung cancer treated with thoracic radiotherapy alone or in combination with chemotherapy.
964. A randomized, controlled trial of foscarnet in the treatment of cytomegalovirus retinitis in patients with AIDS.
作者: A G Palestine.;M A Polis.;M D De Smet.;B F Baird.;J Falloon.;J A Kovacs.;R T Davey.;J J Zurlo.;K M Zunich.;M Davis.
来源: Ann Intern Med. 1991年115卷9期665-73页
To evaluate foscarnet sodium in treating cytomegalovirus retinitis in patients with AIDS.
965. Influence of gastric acidity on the bioavailability of digoxin.
作者: A F Cohen.;R Kroon.;R Schoemaker.;H Hoogkamer.;A van Vliet.
来源: Ann Intern Med. 1991年115卷7期540-5页
To study how changes in gastric acidity induced by omeprazole and pentagastrin affect the absorption of unchanged digoxin and its hydrolytic breakdown products.
966. Reversible renal insufficiency due to angiotensin converting enzyme inhibitors in hypertensive nephrosclerosis.
To review the incidence of reversible renal insufficiency in patients with hypertensive nephrosclerosis undergoing antihypertensive therapy.
967. Effect of vitamin D supplementation on wintertime and overall bone loss in healthy postmenopausal women.
作者: B Dawson-Hughes.;G E Dallal.;E A Krall.;S Harris.;L J Sokoll.;G Falconer.
来源: Ann Intern Med. 1991年115卷7期505-12页
To determine whether relative vitamin D deficiency during the winter months contributes to age-related bone loss and whether rates of change in hard- and soft-tissue mass vary during the year.
968. Loop diuretics for chronic renal insufficiency: a continuous infusion is more efficacious than bolus therapy.
作者: D W Rudy.;J R Voelker.;P K Greene.;F A Esparza.;D C Brater.
来源: Ann Intern Med. 1991年115卷5期360-6页
To test the hypothesis that a continuous, low-dose infusion of a loop diuretic is more efficacious and better tolerated than conventional intermittent bolus therapy in patients with severe chronic renal insufficiency (CRI).
969. Oral mesalamine (Asacol) for mildly to moderately active ulcerative colitis. A multicenter study.
作者: C A Sninsky.;D H Cort.;F Shanahan.;B J Powers.;J T Sessions.;R E Pruitt.;W H Jacobs.;S K Lo.;S R Targan.;J J Cerda.
来源: Ann Intern Med. 1991年115卷5期350-5页
To evaluate the efficacy and safety of a pH-sensitive, polymer-coated oral preparation of mesalamine in patients with mildly to moderately active ulcerative colitis.
970. Effect of triple therapy (antibiotics plus bismuth) on duodenal ulcer healing. A randomized controlled trial.
To determine whether antimicrobial therapy for Helicobacter pylori infection accelerates the healing of duodenal ulcers.
971. Hemorrhagic events during therapy with recombinant tissue-type plasminogen activator, heparin, and aspirin for acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI), Phase II Trial.
作者: E G Bovill.;M L Terrin.;D C Stump.;A D Berke.;M Frederick.;D Collen.;F Feit.;J M Gore.;L D Hillis.;C T Lambrew.
来源: Ann Intern Med. 1991年115卷4期256-65页
To assess the effects of invasive procedures, hemostatic and clinical variables, the timing of beta-blocker therapy, and the doses of recombinant plasminogen activator (rt-PA) on hemorrhagic events.
972. Aminophylline therapy for acute bronchospastic disease in the emergency room.
To assess the role of aminophylline in the treatment of acute exacerbations of bronchospastic disease when used in addition to inhaled beta-agonists and intravenous corticosteroids.
973. Misoprostol compared with sucralfate in the prevention of nonsteroidal anti-inflammatory drug-induced gastric ulcer. A randomized, controlled trial.
作者: N M Agrawal.;S Roth.;D Y Graham.;R H White.;B Germain.;J A Brown.;S C Stromatt.
来源: Ann Intern Med. 1991年115卷3期195-200页
To compare the efficacy and frequency of adverse experiences of misoprostol and sucralfate in the prevention of gastric ulcers in patients receiving nonsteroidal anti-inflammatory drug (NSAID) therapy.
975. Response to treatment with the leukocyte-derived immunomodulator IMREG-1 in immunocompromised patients with AIDS-related complex. A multicenter, double-blind, placebo-controlled trial.
作者: M S Gottlieb.;R A Zackin.;M Fiala.;D H Henry.;A J Marcel.;K L Combs.;J Vieira.;H A Liebman.;L A Cone.;K S Hillman.
来源: Ann Intern Med. 1991年115卷2期84-91页
To determine if a 6-month course of therapy with IMREG-1, a leukocyte-derived immunomodulator, slows disease progression in patients with AIDS-related complex.
976. Prevention of bacterial infection in neutropenic patients with hematologic malignancies. A randomized, multicenter trial comparing norfloxacin with ciprofloxacin. The GIMEMA Infection Program. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto.
来源: Ann Intern Med. 1991年115卷1期7-12页
To compare the efficacy of norfloxacin and ciprofloxacin in preventing bacterial infection in neutropenic patients.
977. Influence of methotrexate and azathioprine on radiologic progression in rheumatoid arthritis. A randomized, double-blind study.
作者: M E Jeurissen.;A M Boerbooms.;L B van de Putte.;W H Doesburg.;A M Lemmens.
来源: Ann Intern Med. 1991年114卷12期999-1004页
To compare the effects of azathioprine and methotrexate on progression of radiologic damage in patients with rheumatoid arthritis.
978. Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia. A randomized, placebo-controlled study.
作者: J S Montaner.;L M Lawson.;A Gervais.;R H Hyland.;C K Chan.;J M Falutz.;P M Renzi.;D MacFadden.;A R Rachlis.;I W Fong.
来源: Ann Intern Med. 1991年114卷11期948-53页
To assess the safety and efficacy of aerosol pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS).
979. Plasmapheresis does not increase the risk for infection in immunosuppressed patients with severe lupus nephritis. The Lupus Nephritis Collaborative Study Group.
To determine whether plasmapheresis increases the risk for infection in immunosuppressed patients.
980. Propranolol compared with propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis. A randomized controlled study.
To investigate whether isosorbide-5-mononitrate (Is-5-Mn) given with propranolol reduces hepatic portal pressure more than does propranolol alone in patients with cirrhosis.
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