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944. Long-Term Spending of Accountable Care Organizations in the Medicare Shared Savings Program.
作者: Amelia M Bond.;Yasin Civelek.;William L Schpero.;Lawrence P Casalino.;Manyao Zhang.;Reekarl Pierre.;Dhruv Khullar.
来源: JAMA. 2025年333卷21期1897-1905页
Evidence from initial cohorts of accountable care organizations (ACOs) participating in the Medicare Shared Savings Program (MSSP) found modest reductions in health care spending. Little is known about whether these effects have changed over time.
945. Non-Cystic Fibrosis Bronchiectasis in Adults: A Review.
Non-cystic fibrosis (CF) bronchiectasis is a chronic lung condition caused by permanent bronchial dilatation and inflammation and is characterized by daily cough, sputum, and recurrent exacerbations. Approximately 500 000 people in the US have non-CF bronchiectasis.
958. Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A Randomized Clinical Trial.
作者: Feng Pan.;Yuanyuan Wang.;Yuan Z Lim.;Donna M Urquhart.;Mahnuma Mahfuz Estee.;Anita E Wluka.;Rory Wolfe.;Flavia M Cicuttini.
来源: JAMA. 2025年333卷20期1804-1812页
Preclinical and preliminary human evidence suggests that metformin, a first-line treatment for type 2 diabetes, reduces inflammation, preserves cartilage, and improves knee pain in knee osteoarthritis.
960. Modeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the US.
作者: Mathew V Kiang.;Kate M Bubar.;Yvonne Maldonado.;Peter J Hotez.;Nathan C Lo.
来源: JAMA. 2025年333卷24期2176-2187页
Widespread childhood vaccination has eliminated many infectious diseases in the US. However, vaccination rates are declining, and there are ongoing policy debates to reduce the childhood vaccine schedule, which may risk reemergence of previously eliminated infectious diseases.
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