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901. Histamine-2 receptor antagonists do not alter serum ethanol levels in fed, nonalcoholic men.
作者: J P Raufman.;V Notar-Francesco.;R D Raffaniello.;E W Straus.
来源: Ann Intern Med. 1993年118卷7期488-94页
To determine whether the four histamine-2 receptor antagonists currently available for the treatment of acid-peptic disorders in the United States alter serum ethanol levels after moderate alcohol consumption.
902. Efficacy of oral ondansetron in the prevention of emesis in outpatients receiving cyclophosphamide-based chemotherapy. The Ondansetron Study Group.
作者: T M Beck.;A A Ciociola.;S E Jones.;W H Harvey.;N S Tchekmedyian.;A Chang.;D Galvin.;N E Hart.
来源: Ann Intern Med. 1993年118卷6期407-13页
To evaluate the efficacy and safety of oral ondansetron (Zofran) as an antiemetic in patients receiving cyclophosphamide-based chemotherapy.
903. Alternating and intermittent regimens of zidovudine and dideoxycytidine in patients with AIDS or AIDS-related complex.
作者: G Skowron.;S A Bozzette.;L Lim.;C B Pettinelli.;H H Schaumburg.;J Arezzo.;M A Fischl.;W G Powderly.;D J Gocke.;D D Richman.;J C Pottage.;D Antoniskis.;G F McKinley.;N E Hyslop.;G Ray.;G Simon.;N Reed.;M L LoFaro.;R B Uttamchandani.;L D Gelb.;S J Sperber.;R L Murphy.;J M Leedom.;M H Grieco.;J Zachary.;M S Hirsch.;S A Spector.;J Bigley.;W Soo.;T C Merigan.
来源: Ann Intern Med. 1993年118卷5期321-30页
To determine whether alternating regimens consisting of zidovudine and 2',3'-dideoxycytidine (ddC) reduce the toxicity and maintain or increase the antiretroviral effect associated with each drug alone.
904. Improvement of lipid abnormalities associated with proteinuria using fosinopril, an angiotensin-converting enzyme inhibitor.
To examine whether reducing protein excretion in patients with proteinuric renal disease using an angiotensin-converting enzyme inhibitor, fosinopril sodium, would be accompanied by an amelioration of the associated hyperlipidemia.
905. Oral acyclovir to suppress frequently recurrent herpes labialis. A double-blind, placebo-controlled trial.
作者: J F Rooney.;S E Straus.;M L Mannix.;C R Wohlenberg.;D W Alling.;J A Dumois.;A L Notkins.
来源: Ann Intern Med. 1993年118卷4期268-72页
To determine whether oral acyclovir reduces the incidence of recurrent herpes labialis in otherwise healthy patients with proven frequently recurrent disease.
906. The risk of determining risk with multivariable models.
To review the principles of multivariable analysis and to examine the application of multivariable statistical methods in general medical literature.
907. What is the benefit of increasing the sulfonylurea dose?
To study the clinical benefit of increasing the dose of the sulfonylurea, glipizide, from 10 to 40 mg per day.
908. Ganciclovir prophylaxis of cytomegalovirus infection and disease in allogeneic bone marrow transplant recipients. Results of a placebo-controlled, double-blind trial.
作者: D J Winston.;W G Ho.;K Bartoni.;C Du Mond.;D F Ebeling.;W C Buhles.;R E Champlin.
来源: Ann Intern Med. 1993年118卷3期179-84页
To evaluate the efficacy and safety of ganciclovir for prevention of cytomegalovirus (CMV) infection and disease.
909. Ganciclovir prophylaxis to prevent cytomegalovirus disease after allogeneic marrow transplant.
作者: J M Goodrich.;R A Bowden.;L Fisher.;C Keller.;G Schoch.;J D Meyers.
来源: Ann Intern Med. 1993年118卷3期173-8页
To study the efficacy and toxicity of ganciclovir prophylaxis given at engraftment to cytomegalovirus (CMV)-seropositive, allogeneic bone marrow transplant recipients.
910. Beta-blockers after myocardial infarction: influence of first-year clinical course on long-term effectiveness.
To develop a strategy for evaluating drug efficacy over time that accounts for heterogeneous clinical courses evolving after initiation of therapy and to demonstrate its use in assessing the long-term therapeutic benefit of propranolol after myocardial infarction.
911. Tolrestat for mild diabetic neuropathy. A 52-week, randomized, placebo-controlled trial.
作者: D Giugliano.;R Marfella.;A Quatraro.;N De Rosa.;T Salvatore.;D Cozzolino.;A Ceriello.;R Torella.
来源: Ann Intern Med. 1993年118卷1期7-11页
To evaluate the effectiveness and safety of tolrestat, an aldose-reductase inhibitor, in patients with mild diabetic autonomic and peripheral neuropathy.
912. Measured enthusiasm: does the method of reporting trial results alter perceptions of therapeutic effectiveness?
To compare clinicians' ratings of therapeutic effectiveness when different trial end points were presented as percent reductions in relative compared with absolute risk and as numbers of patients treated to avoid one adverse outcome.
913. Effect of HIV antibody testing and AIDS education on communication about HIV risk and sexual behavior. A randomized, controlled trial in college students.
作者: N S Wenger.;J M Greenberg.;L H Hilborne.;F Kusseling.;M Mangotich.;M F Shapiro.
来源: Ann Intern Med. 1992年117卷11期905-11页
To evaluate the effects of human immunodeficiency virus (HIV) antibody testing and education about HIV infection on communication about sexual risk behaviors for HIV transmission.
914. How well do internal medicine faculty members evaluate the clinical skills of residents?
作者: G L Noel.;J E Herbers.;M P Caplow.;G S Cooper.;L N Pangaro.;J Harvey.
来源: Ann Intern Med. 1992年117卷9期757-65页
To determine the accuracy of faculty evaluations of residents' clinical skills and whether a structured form and instructional videotape improve accuracy.
915. Recombinant human erythropoietin in the treatment of anemia associated with human immunodeficiency virus (HIV) infection and zidovudine therapy. Overview of four clinical trials.
作者: D H Henry.;G N Beall.;C A Benson.;J Carey.;L A Cone.;L J Eron.;M Fiala.;M A Fischl.;S J Gabin.;M S Gottlieb.
来源: Ann Intern Med. 1992年117卷9期739-48页
To assess the effect of recombinant human erythropoietin (r-HuEPO) on anemia in patients with the acquired immunodeficiency syndrome (AIDS) who are receiving zidovudine therapy.
916. Treatment of shigellosis: III. Comparison of one- or two-dose ciprofloxacin with standard 5-day therapy. A randomized, blinded trial.
To determine whether a single dose, or 2 doses, of ciprofloxacin are as effective as 5-day, 10-dose therapy for the treatment of shigellosis in adult men who are moderately to severely ill.
917. Octreotide treatment of acromegaly. A randomized, multicenter study.
作者: S Ezzat.;P J Snyder.;W F Young.;L D Boyajy.;C Newman.;A Klibanski.;M E Molitch.;A E Boyd.;L Sheeler.;D M Cook.
来源: Ann Intern Med. 1992年117卷9期711-8页
To determine the effects of the somatostatin analog, octreotide acetate, in patients with acromegaly.
918. Protective efficacy of combined live intranasal and inactivated influenza A virus vaccines in the elderly.
作者: J J Treanor.;H R Mattison.;G Dumyati.;A Yinnon.;S Erb.;D O'Brien.;R Dolin.;R F Betts.
来源: Ann Intern Med. 1992年117卷8期625-33页
To evaluate the efficacy of adding intranasal live attenuated cold-adapted influenza A vaccine to inactivated influenza vaccine to prevent influenza A in elderly residents of long-term-care institutions.
919. Fluconazole compared with ketoconazole for the treatment of Candida esophagitis in AIDS. A randomized trial.
作者: L Laine.;R H Dretler.;C N Conteas.;C Tuazon.;F M Koster.;F Sattler.;K Squires.;M Z Islam.
来源: Ann Intern Med. 1992年117卷8期655-60页
To determine the clinical and endoscopic response of candida esophagitis to antifungal therapy and to compare the two oral antifungal agents, fluconazole and ketoconazole.
920. Effects of offering advance directives on medical treatments and costs.
作者: L J Schneiderman.;R Kronick.;R M Kaplan.;J P Anderson.;R D Langer.
来源: Ann Intern Med. 1992年117卷7期599-606页
To examine the effects of advance directives on medical treatments and on patient satisfaction and well-being and to determine whether the enhancement of patient autonomy through advance directives provides a more ethically feasible approach to cost control than does the imposition of limits through rationing.
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