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866. Framework for Research Gaps in Pediatric Ventilator Liberation.
作者: Samer Abu-Sultaneh.;Narayan Prabhu Iyer.;Analía Fernández.;Lyvonne N Tume.;Martin C J Kneyber.;Yolanda M López-Fernández.;Guillaume Emeriaud.;Padmanabhan Ramnarayan.;Robinder G Khemani.; .; .
来源: Chest. 2024年166卷5期1056-1070页
The 2023 International Pediatric Ventilator Liberation Clinical Practice Guidelines provided evidence-based recommendations to guide pediatric critical care providers on how to perform daily aspects of ventilator liberation. However, because of the lack of high-quality pediatric studies, most recommendations were conditional based on very low to low certainty of evidence.
867. Diffusing Capacity of the Lungs for Carbon Monoxide and Echocardiographic Parameters in Identifying Mild Pulmonary Hypertension in the EUSTAR Cohort of Patients With Systemic Sclerosis.
作者: Amalia Colalillo.;Eric Hachulla.;Chiara Pellicano.;Vanessa Smith.;Christina Bergmann.;Gabriela Riemekasten.;Elisabetta Zanatta.;Jörg Henes.;David Launay.;Antonella Marcoccia.;Ana Maria Gheorghiu.;Marie-Elise Truchetet.;Florenzo Iannone.;Carmen Pilar Simeón Aznar.;Susana Oliveira.;Madelon Vonk.;Francesco Del Galdo.;Edoardo Rosato.; .
来源: Chest. 2024年166卷4期837-844页
The 2022 European Society of Cardiology/European Respiratory Society guidelines define pulmonary hypertension (PH) as a resting mean pulmonary artery pressure (mPAP) > 20 mm Hg at right heart catheterization (RHC). Previously, patients with an mPAP between 21 and 24 mm Hg were classified in a "gray zone" of unclear clinical significance.
868. Effective Behaviors of Leaders During Clinical Emergencies: A Qualitative Study of Followers' Perspectives.
To manage a clinical emergency effectively, physicians need well-developed leadership skills, yet limited structured leadership training is available for critical care trainees. To develop an effective curriculum, leadership competencies must first be defined.
870. The Clinical and Economic Implications of Different Treatment Pathways for Patients With Rapidly Recurrent Malignant Pleural Effusion.
作者: David E Ost.;Claudia Goldblatt.;Molly Jung.;Mia Weiss.;Shibei Xu.;Ashley Taneja.;Erik Erdal.
来源: Chest. 2024年166卷4期867-881页
Malignant pleural effusion (MPE) is a common cancer complication. Clinical and economic implications of different recurrent MPE treatment pathways have not been evaluated fully.
871. Management Strategies for Acute Pulmonary Embolism in the ICU.
作者: W Cameron McGuire.;Lauren Sullivan.;Mazen F Odish.;Brinda Desai.;Timothy A Morris.;Timothy M Fernandes.
来源: Chest. 2024年166卷6期1532-1545页
Acute pulmonary embolism (PE) is a common disease encountered by pulmonologists, cardiologists, and critical care physicians throughout the world. For patients with high-risk acute PE (defined by systemic hypotension) and intermediate high-risk acute PE (defined by the absence of systemic hypotension, but the presence of numerous other concerning clinical and imaging features), intensive care often is necessary. Initial management strategies should focus on optimization of right ventricle (RV) function while decisions about advanced interventions are being considered.
872. Understanding the Added Value of High-Resolution CT Beyond Chest X-Ray in Determining Extent of Physiologic Impairment.
作者: Bryan S Benn.;William L Lippitt.;Isabel Cortopassi.;G K Balasubramani.;Eduardo J Mortani Barbosa.;Wonder P Drake.;Erica Herzog.;Kevin Gibson.;Edward S Chen.;Laura L Koth.;Carl Fuhrman.;David A Lynch.;Naftali Kaminski.;Stephen R Wisniewski.;Nichole E Carlson.;Lisa A Maier.
来源: Chest. 2024年166卷5期1093-1107页
Sarcoidosis staging primarily has relied on the Scadding chest radiographic system, although chest CT imaging is finding increased clinical use.
873. Clinical Features, Diagnostics, Etiology, and Outcomes of Hospitalized Solid Organ Recipients With Community-Acquired Pneumonia: A Retrospective Cohort Analysis.
作者: Oana Joean.;Laura Petra von Eynern.;Tobias Welte.;Gunilla Einecke.;Sabine Dettmer.;Jan Fuge.;Richard Taubert.;Heiner Wedemeyer.;Jessica Rademacher.
来源: Chest. 2024年166卷4期697-707页
Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide. Limited evidence is available on the most effective diagnostic approaches, management strategies, and long-term outcomes for CAP in patients who have undergone solid organ transplantation.
874. Quantifying Diaphragm Blood Flow With Contrast-Enhanced Ultrasound in Humans.
作者: Jordan D Bird.;Megan L Lance.;Ty R W Banser.;Scott F Thrall.;Paul D Cotton.;Jonathan R Lindner.;Neil D Eves.;Paolo B Dominelli.;Glen E Foster.
来源: Chest. 2024年166卷4期821-834页
Despite the known interplay between blood flow and function, to our knowledge, there is currently no minimally invasive method to monitor diaphragm hemodynamics. We used contrast-enhanced ultrasound to quantify relative diaphragm blood flow (Q˙DIA) in humans and assessed the technique's efficacy and reliability during graded inspiratory pressure threshold loading. We hypothesized that: (1) Q˙DIA would linearly increase with pressure generation, and (2) that there would be good test-retest reliability and interanalyzer reproducibility.
875. Pulmonary Hypertension in Interstitial Lung Disease: A Systematic Review and Meta-Analysis.
作者: Hui Li Ang.;Max Schulte.;Roseanne Kimberley Chan.;Hann Hsiang Tan.;Amelia Harrison.;Christopher J Ryerson.;Yet Hong Khor.
来源: Chest. 2024年166卷4期778-792页
Pulmonary hypertension (PH) is a key complication in interstitial lung disease (ILD), with recent therapeutic advances.
876. The Cost-Effectiveness of Sleep Apnea Management: A Critical Evaluation of the Impact of Therapy on Health Care Costs.
OSA is a widespread condition that significantly affects both health and health-related quality of life (HRQoL). If left untreated, OSA can lead to accidents, decreased productivity, and medical complications, resulting in significant economic burdens including the direct costs of managing the disorder. Given the constraints on health care resources, understanding the cost-effectiveness of OSA management is crucial. A key factor in cost-effectiveness is whether OSA therapies reduce medical costs associated with OSA-related complications.
877. Sleep Apnea and Stroke: A Narrative Review.
Stroke is the second-leading cause of death worldwide. OSA is an independent risk factor for stroke and is associated with multiple vascular risk factors. Poststroke OSA is prevalent and closely linked with various stroke subtypes, including cardioembolic stroke and cerebral small vessel disease. Observational studies have shown that untreated poststroke OSA is associated with an increased risk of recurrent stroke, mortality, poorer functional recovery, and longer hospitalizations.
878. Understanding Washington State's Low Uptake of Lung Cancer Screening in Two Steps: A Geospatial Analysis of Patient Travel Time and Health Care Availability of Imaging Sites.
作者: Allison C Welch.;Jed A Gorden.;Stephen J Mooney.;Candice L Wilshire.;Steven B Zeliadt.
来源: Chest. 2024年166卷3期622-631页
Early detection of lung cancer reduces cancer mortality; yet uptake for lung cancer screening (LCS) has been limited in Washington State. Geographic disparities contribute to low uptake, but do not wholly explain gaps in access for underserved populations. Other factors, such as an adequate workforce to meet population demand and the capacity of accredited screening facility sites, must also be considered.
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