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821. Negative pressure wound therapy in high-risk gastrointestinal surgery: a retrospective cohort study on postoperative complications.
Surgical site infections (SSIs) are a significant cause of morbidity in colorectal surgeries, mainly due to the contaminated nature of these procedures. Traditional wound management techniques have limitations, leading to prolonged hospital stays and increased healthcare costs. Negative pressure wound therapy (NPWT) has emerged as an advanced method for managing surgical wounds, promoting faster healing by enhancing tissue perfusion, reducing edema, and managing wound exudate. This retrospective cohort study aims to compare the outcomes of NPWT with those of conventional wound care in patients undergoing high-risk gastrointestinal surgeries.
822. Bioinformatics analysis and in vitro studies identify COX7C as a prognostic predictor in gastric adenocarcinoma.
作者: Conglai Shi.;Qiang Wang.;Xin Zhang.;Weiguo Wang.;Wei Wang.;Ziran Wei.;Yue Liu.
来源: BMC Gastroenterol. 2025年25卷1期741页
Stomach adenocarcinoma (STAD) remains a significant threat to human health. This study sought to discover clinically relevant biomarkers for STAD by integrating bioinformatics analysis and in vitro experimental methods.
823. Efficacy of hydration combined with rectal non-steroidal anti-inflammatory drugs (NSAIDs) versus NSAIDs alone for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and meta-analysis of randomized controlled trials.
作者: Huimin Li.;Changfeng Miao.;Wei Fang.;Yuan Deng.;Xiong Li.;Ting Du.;Hongwei Tian.
来源: BMC Gastroenterol. 2025年25卷1期738页
The most prevalent complication of endoscopic retrograde cholangiopancreatography (ERCP) is post-ERCP acute pancreatitis (PEP). Both hydration and rectal non-steroidal anti-inflammatory drugs (NSAIDs) can effectively prevent PEP; however, there is currently no consensus on whether combination therapy is more effective than either intervention alone.
824. Development and validation of a novel nomogram incorporating psychosocial factors for predicting hypoglycemia during perioperative period of digestive endoscopy (DREAM-Hypo Model).
Perioperative hypoglycemia during digestive endoscopy poses significant risks, with reported incidence rates of 6.75-18.70%. Traditional models focus on metabolic factors, while psychosocial stressors (anxiety, poor sleep quality) may exacerbate risk through neuroendocrine dysregulation. This study aims to develop a novel nomogram (DREAM-Hypo Model) integrating psychosocial, clinical, and metabolic predictors for hypoglycemia risk stratification.
825. Serum markers and gastric cancer: an umbrella review.
作者: Afra Darvishi.;Amirhosein Dadashzadeh Asl.;Pouya Golshaniniya.;Ali Alipour.;Amirreza Naseri.;Sina Hamzehzadeh.;Hanieh Salehi-Pourmehr.
来源: BMC Gastroenterol. 2025年25卷1期737页
Early detection of gastric cancer (GC) is crucial for lowering the mortality risk and health burden. Since various biomarkers have been studied for the early diagnosis of GC, this umbrella focuses on the serum markers valuable in GC, for whether detecting or predicting the risk.
826. Association of cardiometabolic risk burden with gastrointestinal bleeding in aspirin users.
作者: Yajing Wei.;Jiamin Yan.;Ziting Gao.;Hongye Wei.;Ziyi Qiu.;Jun Xiao.;Wuqing Huang.
来源: BMC Gastroenterol. 2025年25卷1期736页
Aspirin is widely used in patients with ischemic cardiovascular diseases, most of whom have cardiometabolic disorders. This study aimed to investigate the impact of cardiometabolic risk burden on first gastrointestinal (GI) bleeding in aspirin users.
827. Population stratified differences between ATG16L1 rs2241880 polymorphism with Crohn's disease risk: a systematic review and meta-analysis.
ATG16L1 rs2241880 (T300A), a single-nucleotide variant, plays a controversial role in the development of Crohn's disease (CD).
828. Predicting mortality and readmission in UGIB: a comparative study of rockall, glasgow-blatchford, and AIMS65 scores.
作者: Mehdi Nasr Isfahani.;Masoud Fallah.;Peyman Adibi Sedeh.;Alireza Abootalebi Ghahnavieh.
来源: BMC Gastroenterol. 2025年25卷1期727页
Upper gastrointestinal bleeding (UGIB) is a frequent emergency requiring prompt risk stratification for effective management. This study evaluates the predictive accuracy of three pre-endoscopic scoring systems-Glasgow-Blatchford Score (GBS), AIMS65, and pre-endoscopic Rockall Score (pRS)-in forecasting 30-day mortality and hospital readmission among UGIB patients in Iranian tertiary hospitals.
829. Global prevalence of chronic kidney disease and its influencing factors among chronic hepatitis B: a systematic review and meta-analysis.
作者: Juping Chen.;Wenkai Zhou.;Can Chen.;Fenfang Mi.;Rongrong Qu.;Mengsha Chen.;Kexin Cao.;Xiaoyue Wu.;Jiaxing Qi.;Dong Yan.;Shigui Yang.
来源: BMC Gastroenterol. 2025年25卷1期725页
A comprehensive understanding of the prevalence of chronic kidney disease (CKD) among patients with chronic hepatitis B (CHB) is lacking. To fill this knowledge gap, we conducted a systematic review and meta-analysis to assess the prevalence of CKD and its associated factors among CHB patients.
830. Efficacy and safety of percutaneous papillary balloon dilation for common bile duct stones: a systematic review and meta-analysis.
This study aims to assess the safety and effectiveness of percutaneous papillary balloon dilation for treating common bile duct stones (CBDS), which can provide more evidence to assist clinicians in making decisions when endoscopy or surgery is not feasible for patients.
831. Predictive factors for the coexistence of colorectal lateral spreading tumors and colorectal polyps, and risk factors for malignancy.
作者: Qingwen Yuan.;Jiafu Song.;Zhimei Zhang.;Shuxian Zhang.;Xuyang Liang.
来源: BMC Gastroenterol. 2025年25卷1期731页
Colorectal laterally spreading tumors (LSTs) are precancerous lesions with potential for malignant transformation. The coexistence of LSTs with colorectal polyps may indicate increased risk for early colorectal cancer, yet the associated clinicopathological risk factors remain poorly defined.
832. Association of cardiometabolic index with non-alcoholic fatty liver disease among Iranian adults of the amol cohort study.
作者: Catherine Behzad.;Zainab Shateri.;Nima Motamed.;Mansooreh Maadi.;Hossein Ajdarkosh.;Elham Sobhrakhshankhah.;Farhad Zamani.;Azam Doustmohammadian.;Mehran Nouri.
来源: BMC Gastroenterol. 2025年25卷1期729页
Several studies have demonstrated that the cardiometabolic index (CMI) is associated with multiple health conditions. These include kidney diseases, cardiovascular diseases, stroke, and hypertension. The objective of the present research was to investigate the relationship of CMI with the risk of non-alcoholic fatty liver disease (NAFLD) in a sample of the Iranian population.
833. Association of pleural effusion on thoracic ultrasound with severe acute pancreatitis and mortality.
作者: Michelle Sánchez-Maure.;Erick Joel Rendón-Ramírez.;Joel Omar Jáquez Quintana.;Homero Nañez-Terreros.;Ricardo Cesar Solis.;Héctor Enrique Cedillo-Huerta.;Alexandra Daniela Magaña-García.;Samantha Medrano-Juárez.;Oralia Nava-Rodriguez.;Javier Obeso.;José M Porcel.
来源: BMC Gastroenterol. 2025年25卷1期730页
Acute pancreatitis (AP) is an inflammatory condition associated with significant morbidity and mortality that often leads to thoracic complications. Timely identification of these complications, including pleural effusion (PE), is of utmost importance because it may indicate AP severity.
834. Aberrant alternative splicing in alcoholic hepatitis: regulatory roles of RBPs and sQTLs.
作者: Jinjiang Zhao.;Jie Cheng.;Shaohua Liang.;Wei Guo.;Beibei Zhao.;Huipeng Zhang.;Xianghuang Mei.;Ning Zhang.;Meifang Sheng.
来源: BMC Gastroenterol. 2025年25卷1期728页
Alternative splicing (AS) plays a critical role in gene regulation, contributing to transcriptomic complexity and disease progression.
835. Prevalence, demographic characteristics and clinical profile of metabolic dysfunction-associated fatty liver disease among adult patients attending tertiary hospitals in Dodoma, Tanzania. a cross-sectional study.
Globally, metabolic dysfunction-associated fatty liver disease (MAFLD) has become one of the leading causes of liver disease, attributed to the rapid increase in obesity. There is paucity of data on the burden of MAFLD in Tanzania. The study assessed MAFLD prevalence and associated factors among adult patients in Dodoma,
836. Tube-bearing experience of patients with biliary and pancreatic diseases outside the hospital: based on qualitative study.
作者: Jingli Liu.;Xiaoping Ye.;Shuling Chang.;Ziyu Wu.;Bo Yuan.;Qianqian Wang.;Yanrong Yao.
来源: BMC Gastroenterol. 2025年25卷1期733页
This study aimed to understand the experience of patients with external drainage tube out of hospital with biliary and pancreatic system diseases and provide a theoretical basis and reference for formulating nursing intervention measures based on the actual experience of patients with ducts.
837. A retrospective study on the predictive value of D-dimer for mortality in patients with acute arterial occlusive mesenteric ischemia.
作者: Yaliu Yang.;Peng Liu.;Ruilong Gao.;Zhengqin Zhai.;Yifeng Zhou.;Jiahui Li.
来源: BMC Gastroenterol. 2025年25卷1期732页
Acute arterial occlusive mesenteric ischemia (AOMI) is a catastrophic vascular emergency associated with exceedingly high mortality rates. The lack of reliable early prognostic tools creates an urgent need for accessible biomarkers to guide management. This study aimed to evaluate mortality outcomes and assess the prognostic utility of baseline serum D-dimer levels in patients with AOMI.
838. Implementation of enhanced recovery after surgery (ERAS) protocols in elderly patients undergoing emergency surgery for perforated peptic ulcer: a comparative analysis.
作者: Mohamed Wael.;Ahmed S Shehab.;Islam El-Sayes.;Mostafa Ibrahim Ahmed Seif-Eldeen.
来源: BMC Gastroenterol. 2025年25卷1期723页
Enhanced Recovery After Surgery (ERAS) protocols are well-established in elective surgery, yet their role in emergency procedures remains underexplored - particularly in the elderly, a uniquely vulnerable subgroup. This study presents the first focused comparative analysis evaluating ERAS outcomes in elderly patients undergoing emergency surgery for perforated peptic ulcer (PPU).
839. Unmasking the role of constipation in treatment-refractory enterobiasis in Bangladeshi children.
作者: Md Benzamin.;Md Ziaur Rahman Chowdhury.;Pranto Chakroborty.;Akhlaq Ahmed.;Md Moulud Hussen.;Rajib Kanti Dey.;Asm Bazlul Karim.
来源: BMC Gastroenterol. 2025年25卷1期724页
Helminthiasis remains a prevalent health issue among the pediatric population in both developed and developing countries. Recurrent enterobius vermicularis infection is a particularly distressing and sometimes embarrassing condition for children. While sporadic cases are common, repeated infections despite proper hygiene and regular deworming are uncommon and warrant further investigation.
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