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801. Frailty and liver transplant eligibility beyond MELD scores: integrating functional status into candidate selection.
The MELD score, while central to liver transplant prioritization, fails to capture frailty, an important predictor of transplant eligibility and outcomes.
802. Evolution of mortality rates due to gastrointestinal bleeding in Peru and its geographic areas, 2003-2022.
作者: Miguel Andrés Ortiz-Alfaro.;José Carlos Vizcarra-Díaz.;Bryan Rudas-Sulca.;Ivan Alegre-Cordero.;Yenko Damjanovic-Burga.;Julio A Poterico.;Jorge Ybaseta-Medina.;Luis M Tasayco-Marquez.;J Smith Torres-Roman.
来源: BMC Gastroenterol. 2025年25卷1期746页
Gastrointestinal bleeding (GIB) is a common cause of emergency medical admissions and represents a significant public health issue due to its high morbidity and mortality. In Peru, information on mortality rates from GIB disaggregated by region and sex is limited. Therefore, this study aimed to analyze GIB mortality in the country between 2003 and 2022 using official data from the Peruvian Ministry of Health (MINSA).
803. Comparison of sociodemographic factors, lifestyle, and gastrointestinal symptoms between patients with endometriosis and IBS.
作者: Agnes Petersson.;Bodil Roth.;Ligita Jokubkiene.;Povilas Sladkevicius.;Bodil Ohlsson.
来源: BMC Gastroenterol. 2025年25卷1期742页
Endometriosis and Irritable bowel syndrome (IBS) are two common diseases with overlapping symptomatology, causing confusion and delay in the diagnostic process. The objective of this study was to identify differences between endometriosis and IBS diagnosed according to Rome IV, by comparing sociodemographic factors, lifestyle habits, and gastrointestinal symptoms.
804. Metabolic dynamics and stage-specific biomarkers in chronic HBV infection: a metabolomics study.
作者: Lizhi Liu.;Zifei Zhu.;Wenwen Jin.;Xi Su.;Zhonghua Deng.;Cunyan Li.
来源: BMC Gastroenterol. 2025年25卷1期744页
This study was aimed to identify and investigate changes in serum metabolites across the natural progression of chronic hepatitis B (CHB) patients, discover differential metabolites and metabolic pathways in different disease phases, and provide an experimental foundation for clinical diagnosis, staging, treatment, and prognosis of CHB.
805. Investigating microbiota differences across chronic pancreatitis, influenced by lifestyle and genetic determinants.
作者: Abubaker Y M Ahmed.;Azita Rajai.;Catherine Fullwood.;Damian W Rivett.;John McLaughlin.;Christopher van der Gast.;Ryan Marsh.
来源: BMC Gastroenterol. 2025年25卷1期747页
Chronic pancreatitis (CP) is a multifaceted and irreversible inflammatory condition that impacts both endocrine and exocrine pancreatic functions. Whilst there is evidence of a general intestinal microbial dysbiosis, differences across CP resulting from diverse triggers remains poorly elucidated.
806. Mortality risk prediction in liver transplant candidates: a prognostic model using key clinical variables.
作者: Mohammad Hossein Aghazadeh.;Mehdi Azizmohammad Looha.;Yadmehr Khaleghjoo.;Fatemeh Ghoorchi Beigi.;Amirhassan Rabbani.;Tina Parsa.;Yekta Parsa.
来源: BMC Gastroenterol. 2025年25卷1期745页
Accurate mortality prediction is vital for liver transplant allocation, but models like MELD-Na and Child-Pugh may overlook important individual risk factors. This study aimed to develop and validate a prognostic model using key clinical variables and both statistical and machine learning methods.
807. Socioeconomic value of treatments for chronic idiopathic constipation in Japan.
作者: Atsushi Nakajima.;Aki Unno.;Takumi Ota.;Ayako Shoji.;Tatsuhiro Uenishi.;Ataru Igarashi.
来源: BMC Gastroenterol. 2025年25卷1期748页
Chronic idiopathic constipation (CIC) is a common disorder associated with socioeconomic burden. The aim of this study was to quantify the socioeconomic burden of CIC, including non-traditional value elements, and to compare the cost-effectiveness of 3 treatments for CIC with unique mechanisms of action: elobixibat 10 mg, linaclotide 0.5 mg, and lubiprostone 48 μg.
808. Timing of endoscopy in cirrhotic patients with acute variceal bleeding: a multicenter cohort study.
作者: Javier Tejedor-Tejada.;Benito Hermida.;Cristina Camblor.;Samuel Robles.;Mohamed Emara.;Salem Y Mohamed.;Jose M Perez-Pariente.
来源: Minerva Gastroenterol (Torino). 2025年71卷4期315-322页
The optimal timing of endoscopy in cirrhotic patients with acute variceal bleeding (AVB) remains uncertain. The study aimed to determine whether the timing of endoscopy affects short-term outcomes in patients with AVB.
809. AGA Clinical Practice Update on Endoscopic Resection for Early Colorectal Cancer: Commentary.
作者: Saowanee Ngamruengphong.;Mohamed O Othman.;Andrew Y Wang.;Dennis Yang.
来源: Gastroenterology. 2025年169卷7期1558-1564页
T1 colorectal cancer (CRC), defined as tumor invasion confined to the submucosa, has traditionally been managed by surgery. Advances in endoscopic resection techniques, coupled with an improved understanding of tumor biology and risk of lymph node metastasis and recurrence, have expanded our treatment armamentarium for these lesions. The purpose of this American Gastroenterological Association (AGA) Clinical Practice Update Expert Commentary is to review the definition of T1 CRC, discuss the role of endoscopic resection for these lesions, review factors associated with risk of recurrence and metastasis, and discuss post-resection management, including surveillance or adjuvant surgery. The target audience for this commentary includes primary care, gastroenterology, pathology, and surgical health care professionals.
810. Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Crohn's Disease: 2025 AGA Evidence Synthesis.
作者: Siddharth Singh.;M Hassan Murad.;Yuhong Yuan.;Ashwin N Ananthakrishnan.;Benjamin Click.;Gaurav Syal.;John P Haydek.;Manasi Agrawal.;Michael D Kappelman.;James D Lewis.;Frank I Scott.
来源: Gastroenterology. 2025年169卷7期1516-1536页
We performed an updated systematic review and network meta-analysis to inform the 2025 American Gastroenterological Association Clinical Guidelines on the management of moderate-to-severe Crohn's disease (CD).
811. AGA Clinical Practice Update on the Management of Ascites, Volume Overload, and Hyponatremia in Cirrhosis: Expert Review.
作者: Eric S Orman.;Brett E Fortune.;Binu V John.;Sumeet K Asrani.
来源: Gastroenterology. 2025年169卷7期1547-1557页
The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update (CPU) is to summarize the available evidence and offer expert Best Practice Advice (BPA) on the management of ascites, hepatic hydrothorax, volume overload, and hyponatremia in patients with cirrhosis.
813. Hemodynamic Status as a Determinant Factor of Optimal Endoscopy Timing in Upper Gastrointestinal Bleeding: Results From an International Survey of 533 Clinicians.
作者: Mahmoud Obeidat.;Diana-Elena Floria.;Brigitta Teutsch.;Zsolt Abonyi-Tóth.;Péter Hegyi.;Bálint Erőss.; .
来源: Gastroenterology. 2026年170卷1期199-202页 814. Reduced Esophageal Hypervigilance and Symptom-Specific Anxiety in Barrett's Esophagus: A Deficient Alarm Signal for Gastroesophageal Reflux Disease-Associated Mucosal Injury.
作者: Ming-Wun Wong.;Shih-Hsuan Hsiao.;Jen-Hung Wang.;Chandra Prakash Gyawali.;Peir-Rong Chen.;Chien-Lin Chen.
来源: Gastroenterology. 2025年169卷7期1513-1515页 817. Analysis of "Mebeverine and the Influence of Labeling in Adolescents With Irritable Bowel Syndrome or Functional Abdominal Pain Not Otherwise Specified: A 2 × 2 Randomized, Placebo-Controlled Trial". |