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61. In cardiology outpatients at high stroke risk, smartwatch-based screening vs. usual care increased detection of new onset AF at 180 d.
GIM/FP/GP:[Formula: see text] Cardiology:[Formula: see text] Geriatrics:[Formula: see text].
62. In postmenopausal women at high risk for fracture, romosozumab for 3 mo was noninferior to 12 mo for increasing total hip BMD at 1 y.
Geriatrics:[Formula: see text] Rheumatology:[Formula: see text].
63. In uncomplicated acute appendicitis, initial antibiotic therapy vs. appendectomy had a lower cumulative complication rate at 10 y.
Emergency Med:[Formula: see text] GIM/FP/GP:[Formula: see text] Infectious Disease:[Formula: see text].
64. Tenecteplase 4.5 to 24 h after non-LVO stroke with potentially salvageable brain tissue improved functional outcomes at 90 d.
Emergency Med:[Formula: see text] GIM/FP/GP:[Formula: see text] Neurology:[Formula: see text].
67. In critically ill adults, accuracy of pulse oximeters for detecting hypoxemia varied by skin tone.
GIM/FP/GP:[Formula: see text] Critical Care:[Formula: see text] Pulmonology:[Formula: see text].
71. In adults with T2D and ASCVD, tirzepatide was noninferior to dulaglutide for a composite CV outcome at a median 4 y.
作者: Thomas Karagiannis.;Ioannis Avgerinos.;Apostolos Tsapas.; .
来源: Ann Intern Med. 2026年179卷5期JC53页
GIM/FP/GP:[Formula: see text] Cardiology:[Formula: see text] Endocrinology:[Formula: see text].
76. "Never More Than 15 Feet From the Respirator": Housestaff Research During the 1955 Boston Polio Epidemic.
In July 1955, a devastating polio epidemic struck Massachusetts only 3 months after the licensing of the Salk vaccine. One of the last major polio epidemics in the United States, it overwhelmed the local health care system. At Massachusetts General Hospital, 2 assistant residents-the equivalent of today's postgraduate year 2 trainees-were assigned to oversee a hastily organized polio ward and a rising second-year medical student was charged with setting up and running an adjoining laboratory. There, they and other residents conducted original patient-oriented research while providing round-the-clock care for patients, most in iron lungs, under crisis conditions. Their work was facilitated by a strong preexisting culture of bedside research at the hospital. Extremely long work hours ensured constant, close patient observation. A lack of role boundaries between the physician as researcher and as clinician and an absence of formal requirements for patient consent to research in that era also facilitated the studies, which were of similar methodological sophistication and ethical consideration to contemporaneous studies of other diseases. There is evidence that this experience influenced their subsequent careers. The autonomy granted these trainees contrasts sharply with the restricted roles permitted to medical students and residents during the initial surge of the recent COVID-19 pandemic.
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