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761. Treatment of postmenopausal osteoporosis with slow-release sodium fluoride. Final report of a randomized controlled trial.
作者: C Y Pak.;K Sakhaee.;B Adams-Huet.;V Piziak.;R D Peterson.;J R Poindexter.
来源: Ann Intern Med. 1995年123卷6期401-8页
To test whether slow-release sodium fluoride inhibits spinal fractures and is safe to use.
762. Misoprostol dosage in the prevention of nonsteroidal anti-inflammatory drug-induced gastric and duodenal ulcers: a comparison of three regimens.
作者: J B Raskin.;R H White.;J E Jackson.;A L Weaver.;E A Tindall.;R B Lies.;D S Stanton.
来源: Ann Intern Med. 1995年123卷5期344-50页
To compare the effectiveness and tolerability of three misoprostol dosing regimens for the prevention of gastric and duodenal ulcers associated with long-term nonsteroidal anti-inflammatory drug (NSAID) therapy.
763. Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial.
作者: F E Silverstein.;D Y Graham.;J R Senior.;H W Davies.;B J Struthers.;R M Bittman.;G S Geis.
来源: Ann Intern Med. 1995年123卷4期241-9页
To investigate whether concurrent administration of misoprostol reduces the occurrence of serious upper gastrointestinal complications, such as perforation, gastric outlet obstruction, or bleeding, in patients with rheumatoid arthritis who are receiving nonsteroidal anti-inflammatory drugs (NSAIDs).
764. Twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent recurrent toxoplasmic encephalitis in patients with AIDS. Spanish Toxoplasmosis Study Group.
作者: D Podzamczer.;J M Miró.;F Bolao.;J M Gatell.;J Cosín.;G Sirera.;P Domingo.;F Laguna.;J Santamaría.;J Verdejo.
来源: Ann Intern Med. 1995年123卷3期175-80页
To evaluate the efficacy of twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent toxoplasmic encephalitis relapse in patients with the acquired immunodeficiency syndrome (AIDS).
765. Mechanical ventilation with or without 7-day circuit changes. A randomized controlled trial.
作者: M H Kollef.;S D Shapiro.;V J Fraser.;P Silver.;D M Murphy.;E Trovillion.;M L Hearns.;R D Richards.;L Cracchilo.;L Hossin.
来源: Ann Intern Med. 1995年123卷3期168-74页
To determine whether a practice of not routinely changing ventilator circuits in patients who require prolonged mechanical ventilation is associated with an increased incidence of nosocomial pneumonia.
766. Effects of naloxone infusions in patients with the pruritus of cholestasis. A double-blind, randomized, controlled trial.
作者: N V Bergasa.;D W Alling.;T L Talbot.;M G Swain.;C Yurdaydin.;M L Turner.;J M Schmitt.;E C Walker.;E A Jones.
来源: Ann Intern Med. 1995年123卷3期161-7页
To determine whether endogenous opioids contribute to the pruritus of cholestasis by studying the effect of the opiate antagonist naloxone on the perception of pruritus and on scratching activity in patients with this form of pruritus.
767. Famciclovir for the treatment of acute herpes zoster: effects on acute disease and postherpetic neuralgia. A randomized, double-blind, placebo-controlled trial. Collaborative Famciclovir Herpes Zoster Study Group.
作者: S Tyring.;R A Barbarash.;J E Nahlik.;A Cunningham.;J Marley.;M Heng.;T Jones.;T Rea.;R Boon.;R Saltzman.
来源: Ann Intern Med. 1995年123卷2期89-96页
To document the effects of treatment with famciclovir on the acute signs and symptoms of herpes zoster and postherpetic neuralgia.
768. Preemptive ganciclovir therapy to prevent cytomegalovirus disease in cytomegalovirus antibody-positive renal transplant recipients. A randomized controlled trial.
作者: P L Hibberd.;N E Tolkoff-Rubin.;D Conti.;F Stuart.;J R Thistlethwaite.;J F Neylan.;D R Snydman.;R Freeman.;M I Lorber.;R H Rubin.
来源: Ann Intern Med. 1995年123卷1期18-26页
To determine whether preemptive ganciclovir therapy administered daily during antilymphocyte antibody therapy can prevent cytomegalovirus disease in renal transplant recipients who are positive for cytomegalovirus antibody.
769. Comparing subcutaneous danaparoid with intravenous unfractionated heparin for the treatment of venous thromboembolism. A randomized controlled trial.
作者: H W de Valk.;J D Banga.;J W Wester.;C B Brouwer.;M W van Hessen.;O J Meuwissen.;H C Hart.;J J Sixma.;H K Nieuwenhuis.
来源: Ann Intern Med. 1995年123卷1期1-9页
To compare the efficacy and safety of two subcutaneous doses of danaparoid with that of continuous intravenous administration of unfractionated heparin in the treatment of venous thromboembolism.
770. Effect of alcohol on acute ventilatory adaptation to mild hypoxia at moderate altitude.
To evaluate the influence of alcohol on acute adaptation to mild hypoxia at moderate altitude.
771. Prophylaxis against gallstone formation with ursodeoxycholic acid in patients participating in a very-low-calorie diet program.
作者: M L Shiffman.;G D Kaplan.;V Brinkman-Kaplan.;F F Vickers.
来源: Ann Intern Med. 1995年122卷12期899-905页
To determine whether prophylactic treatment with ursodeoxycholic acid can prevent gallstone formation in persons participating in a very-low-calorie weight reduction diet program.
772. A recombinant glycoprotein vaccine for herpes simplex virus type 2: safety and immunogenicity [corrected].
作者: A G Langenberg.;R L Burke.;S F Adair.;R Sekulovich.;M Tigges.;C L Dekker.;L Corey.
来源: Ann Intern Med. 1995年122卷12期889-98页
To evaluate the safety and immunogenicity of a recombinant glycoprotein vaccine for herpes simplex virus type 2 (HSV-2), which contains glycoproteins gD2 and gB2 combined with the novel MF59 adjuvant emulsion, in HSV-2-seronegative persons.
773. Effects of pulmonary rehabilitation on physiologic and psychosocial outcomes in patients with chronic obstructive pulmonary disease.
To compare the effects of comprehensive pulmonary rehabilitation with those of education alone on physiologic and psychosocial outcomes in patients with chronic obstructive pulmonary disease.
774. Intermittent trimethoprim-sulfamethoxazole compared with dapsone-pyrimethamine for the simultaneous primary prophylaxis of Pneumocystis pneumonia and toxoplasmosis in patients infected with HIV.
作者: D Podzamczer.;A Salazar.;J Jiménez.;E Consiglio.;M Santín.;A Casanova.;G Rufí.;F Gudiol.
来源: Ann Intern Med. 1995年122卷10期755-61页
To evaluate the efficacy and safety of two oral, intermittent drug regimens for the simultaneous primary prophylaxis of Pneumocystis carinii pneumonia and toxoplasmosis in patients with HIV infection.
775. Does eradicating bacteriuria affect the severity of chronic urinary incontinence in nursing home residents?
作者: J G Ouslander.;M Schapira.;J F Schnelle.;G Uman.;S Fingold.;E Tuico.;J G Nigam.
来源: Ann Intern Med. 1995年122卷10期749-54页
To determine the effects of eradicating otherwise asymptomatic bacteriuria on the severity of chronic urinary incontinence among nursing home residents.
776. Effects of alcohol and fluvastatin on lipid metabolism and hepatic function.
作者: J W Smit.;H J Wijnne.;F Schobben.;A Sitsen.;T W De Bruin.;D W Erkelens.
来源: Ann Intern Med. 1995年122卷9期678-80页
To determine the effects of fluvastatin, a synthetic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, combined with moderate alcohol consumption on lipid profiles and hepatic function in patients with primary hypercholesterolemia.
777. Trimethoprim-sulfamethoxazole for the prevention of spontaneous bacterial peritonitis in cirrhosis: a randomized trial.
To assess the efficacy and safety of trimethoprim-sulfamethoxazole for the prevention of spontaneous bacterial peritonitis in patients with cirrhosis and ascites.
778. Late relapses in patients successfully treated for thrombotic thrombocytopenic purpura. Canadian Apheresis Group.
To determine the incidence and timing of relapses in patients who have recovered from an acute episode of thrombotic thrombocytopenic purpura.
779. The effect of intensive diabetes therapy on the development and progression of neuropathy. The Diabetes Control and Complications Trial Research Group.
来源: Ann Intern Med. 1995年122卷8期561-8页
To examine whether intensive therapy designed to achieve glycemic levels as close to normal as possible prevents or slows the progression of neuropathy when compared with conventional therapy in patients with insulin-dependent diabetes mellitus in the Diabetes Control and Complications Trial.
780. Zidovudine resistance and HIV-1 disease progression during antiretroviral therapy. AIDS Clinical Trials Group Protocol 116B/117 Team and the Virology Committee Resistance Working Group.
作者: R T D'Aquila.;V A Johnson.;S L Welles.;A J Japour.;D R Kuritzkes.;V DeGruttola.;P S Reichelderfer.;R W Coombs.;C S Crumpacker.;J O Kahn.;D D Richman.
来源: Ann Intern Med. 1995年122卷6期401-8页
To evaluate the association between resistance of human immunodeficiency virus type 1 (HIV-1) to zidovudine and clinical progression.
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