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721. Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial.
作者: M F Gourley.;H A Austin.;D Scott.;C H Yarboro.;E M Vaughan.;J Muir.;D T Boumpas.;J H Klippel.;J E Balow.;A D Steinberg.
来源: Ann Intern Med. 1996年125卷7期549-57页
Uncertainty exists about the efficacy and toxicity of bolus therapy with methylprednisolone or of the combination of methylprednisolone and cyclophosphamide in the treatment of lupus nephritis.
722. Effect of combination therapy with lipid-reducing drugs in patients with coronary heart disease and "normal" cholesterol levels. A randomized, placebo-controlled trial. Harvard Atherosclerosis Reversibility Project (HARP) Study Group.
作者: R C Pasternak.;L E Brown.;P H Stone.;D I Silverman.;C M Gibson.;F M Sacks.
来源: Ann Intern Med. 1996年125卷7期529-40页
Combination drug therapy has been shown to decrease cholesterol levels in hyperlipidemic patients. However, its efficacy has not been well studied in patients previously considered to be normolipidemic, many of whom are now candidates for this therapy.
723. Piperacillin to prevent cholangitis after endoscopic retrograde cholangiopancreatography. A randomized, controlled trial.
作者: S J van den Hazel.;P Speelman.;J Dankert.;K Huibregtse.;G N Tytgat.;D J van Leeuwen.
来源: Ann Intern Med. 1996年125卷6期442-7页
Cholangitis does not often occur after endoscopic retrograde cholangiopancreatography (ERCP), but it can be a serious complication of this procedure. Antibiotic prophylaxis is therefore frequently used in patients having ERCP, but existing data are insufficient to allow evaluation of the effectiveness of this practice.
724. Acyclovir with and without prednisone for the treatment of herpes zoster. A randomized, placebo-controlled trial. The National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group.
作者: R J Whitley.;H Weiss.;J W Gnann.;S Tyring.;G J Mertz.;P G Pappas.;C J Schleupner.;F Hayden.;J Wolf.;S J Soong.
来源: Ann Intern Med. 1996年125卷5期376-83页
To determine the effect of acyclovir and prednisone treatment of herpes zoster on chronic pain and quality-of-life outcomes.
725. Effect of hormone replacement therapy on bone mineral density in postmenopausal women with mild primary hyperparathyroidism. A randomized, controlled trial.
作者: A B Grey.;J P Stapleton.;M C Evans.;M A Tatnell.;I R Reid.
来源: Ann Intern Med. 1996年125卷5期360-8页
Most patients with primary hyperparathyroidism are postmenopausal women. The presence of osteopenia in persons with mild primary hyperparathyroidism is considered an indication for parathyroidectomy. No prospective, controlled trials have assessed medical therapies for osteopenia in primary hyperparathyroidism.
726. Formation of antibodies to factor VIII in patients with hemophilia A who are treated with interferon for chronic hepatitis C.
作者: E P Mauser-Bunschoten.;M Damen.;H W Reesink.;G Roosendaal.;R A Chamuleau.;H M van den Berg.
来源: Ann Intern Med. 1996年125卷4期297-9页
To evaluate the risk for development of antibodies to factor VIII (factor VIII inhibitors) during and after interferon therapy in patients with hemophilia A and chronic hepatitis C infection.
727. Safety and immunogenicity of a candidate HIV-1 vaccine in healthy adults: recombinant glycoprotein (rgp) 120. A randomized, double-blind trial. NIAID AIDS Vaccine Evaluation Group.
作者: B S Graham.;M C Keefer.;M J McElrath.;G J Gorse.;D H Schwartz.;K Weinhold.;T J Matthews.;J R Esterlitz.;F Sinangil.;P E Fast.
来源: Ann Intern Med. 1996年125卷4期270-9页
To evaluate the safety and immunogenicity of recombinant glycoprotein (rgp) 120, a candidate vaccine for the human immunodeficiency virus (HIV), formulated with a novel adjuvant, MF59, with or without a biological response modifier, MTP-PE.
728. Quinolone-based antibacterial chemoprophylaxis in neutropenic patients: effect of augmented gram-positive activity on infectious morbidity. National Cancer Institute of Canada Clinical Trials Group.
作者: E J Bow.;L A Mandell.;T J Louie.;R Feld.;M Palmer.;B Zee.;J Pater.
来源: Ann Intern Med. 1996年125卷3期183-90页
To determine whether augmented quinolone-based antibacterial prophylaxis in neutropenic patients with cancer reduces infections caused by gram-positive cocci and preserves the protective effect against aerobic gram-negative bacilli.
729. Lamivudine plus zidovudine compared with zalcitabine plus zidovudine in patients with HIV infection. A randomized, double-blind, placebo-controlled trial. North American HIV Working Party.
作者: J A Bartlett.;S L Benoit.;V A Johnson.;J B Quinn.;G E Sepulveda.;W C Ehmann.;C Tsoukas.;M A Fallon.;P L Self.;M Rubin.
来源: Ann Intern Med. 1996年125卷3期161-72页
To compare the safety and activity of lamivudine plus zidovudine with the safety and activity of zalcitabine plus zidovudine in patients with moderately advanced human immunodeficiency virus (HIV) infection who had received zidovudine.
730. Effectiveness and safety of intranasal ipratropium bromide in common colds. A randomized, double-blind, placebo-controlled trial.
To determine the tolerability and clinical effectiveness of intranasal ipratropium bromide for the treatment of symptoms of common colds.
731. Zinc gluconate lozenges for treating the common cold. A randomized, double-blind, placebo-controlled study.
The common cold is one of the most frequent human illnesses and is responsible for substantial morbidity and economic loss. No consistently effective therapy for the common cold has been well documented, but evidence suggests that several possible mechanisms may make zinc an effective treatment.
732. Exercise training in patients with heart failure. A randomized, controlled trial.
作者: S J Keteyian.;A B Levine.;C A Brawner.;T Kataoka.;F J Rogers.;J R Schairer.;P D Stein.;T B Levine.;S Goldstein.
来源: Ann Intern Med. 1996年124卷12期1051-7页
To assess the benefit of exercise training in patients with heart failure caused by left ventricular systolic dysfunction and to further describe the physiologic changes associated with exercise training in these patients.
733. Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators.
作者: R T D'Aquila.;M D Hughes.;V A Johnson.;M A Fischl.;J P Sommadossi.;S H Liou.;J Timpone.;M Myers.;N Basgoz.;M Niu.;M S Hirsch.
来源: Ann Intern Med. 1996年124卷12期1019-30页
To study the addition of a third human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitor, nevirapine, to the combination of zidovudine and didanosine.
734. Effective maintenance treatment of reflux esophagitis with low-dose lansoprazole. A randomized, double-blind, placebo-controlled trial.
To compare the efficacy of two doses of lansoprazole with that of placebo in preventing recurrence of erosive esophagitis in a 12-month period.
735. Comparison of three regimens for treatment of mild to moderate Pneumocystis carinii pneumonia in patients with AIDS. A double-blind, randomized, trial of oral trimethoprim-sulfamethoxazole, dapsone-trimethoprim, and clindamycin-primaquine. ACTG 108 Study Group.
作者: S Safrin.;D M Finkelstein.;J Feinberg.;P Frame.;G Simpson.;A Wu.;T Cheung.;R Soeiro.;P Hojczyk.;J R Black.
来源: Ann Intern Med. 1996年124卷9期792-802页
To compare the tolerability and efficacy of three oral regimens for the treatment of patients with the acquired immunodeficiency syndrome (AIDS) and Pneumocystis carinii pneumonia.
736. Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial.
作者: B J Luft.;R J Dattwyler.;R C Johnson.;S W Luger.;E M Bosler.;D W Rahn.;E J Masters.;E Grunwaldt.;S D Gadgil.
来源: Ann Intern Med. 1996年124卷9期785-91页
To determine whether azithromycin or amoxicillin is more efficacious for the treatment of erythema migrans skin lesions, which are characteristic of Lyme disease.
737. Once-daily aminoglycoside dosing in immunocompetent adults: a meta-analysis.
To compare the efficacy, nephrotoxicity, and ototoxicity of once-daily aminoglycoside dosing with those of standard aminoglycoside regimens in immuno-competent adults.
738. Growth hormone replacement in healthy older men improves body composition but not functional ability.
作者: M A Papadakis.;D Grady.;D Black.;M J Tierney.;G A Gooding.;M Schambelan.;C Grunfeld.
来源: Ann Intern Med. 1996年124卷8期708-16页
To determine whether growth hormone replacement in older men improves functional ability.
739. The effectiveness of early treatment with "second-line" antirheumatic drugs. A randomized, controlled trial.
作者: A van der Heide.;J W Jacobs.;J W Bijlsma.;A H Heurkens.;C van Booma-Frankfort.;M J van der Veen.;H C Haanen.;D M Hofman.;G A van Albada-Kuipers.;E J ter Borg.;H L Brus.;H J Dinant.;A A Kruize.;Y Schenk.
来源: Ann Intern Med. 1996年124卷8期699-707页
To compare two therapeutic strategies for patients with recent-onset rheumatoid arthritis.
740. Prevention of venous thromboembolism after knee arthroplasty. A randomized, double-blind trial comparing enoxaparin with warfarin.
作者: J R Leclerc.;W H Geerts.;L Desjardins.;G H Laflamme.;B L'Espérance.;C Demers.;J Kassis.;M Cruickshank.;L Whitman.;F Delorme.
来源: Ann Intern Med. 1996年124卷7期619-26页
To compare the effectiveness and safety of fixed-dose enoxaparin and adjusted dose warfarin in preventing venous thromboembolism after knee arthroplasty.
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