To develop a CT-based decision tree model integrating clinical and imaging features for the preoperative differentiation of gastric ectopic pancreas (GEPs) and gastrointestinal stromal tumors (GISTs) with a maximum diameter of less than 3 cm.

Metabolic dysfunction-associated steatotic liver disease (MASLD) frequently coexists with chronic kidney disease, which may exacerbate adverse outcomes. The albumin-to-creatinine ratio (ACR), an established marker of renal damage, has been associated with mortality risk in this population, yet its prognostic value and potential role in related pathways remain unclear.

Transarterial chemoembolization (TACE) is a standard treatment for unresectable hepatocellular carcinoma (HCC). However, a significant proportion of patients develop conventional TACE (cTACE) refractoriness, which is associated with poor prognosis. The optimal treatment strategy for cTACE-refractory HCC remains controversial. This study aimed to evaluate the efficacy and safety of drug-eluting bead TACE (D-TACE) combined with lenvatinib versus cTACE plus lenvatinib in patients with cTACE-refractory HCC.

The global burden of colorectal cancer (CRC) has been steadily rising. However, a key knowledge gap persists regarding the HBMI-attributable burden in early-onset (EOCRC) versus late-onset (LOCRC) cases. The temporal patterns, geographic heterogeneity, and comparative trends remain poorly characterized, as prior studies often lack stratification by age of onset and detailed analysis across socio-demographic strata.

This study examined the link between red cell distribution width - coefficient of variation (RDW-CV) levels, colon cancer, and all-cause mortality in the community population.

Lesions manifesting after radiotherapy are difficult to treat. Significant inflammations often manifest at the rectal wall after radiotherapy, the rectal wall often experiences significant inflammation, and the intestinal cavity is typically in an edematous state.

Esophageal foreign bodies, especially fish bones, are common emergencies that may require surgery like thoracotomy. Psychological impacts such as pain and anxiety are often overlooked. This study explores patients’ psychological experiences during diagnosis, treatment, and recovery to inform effective interventions and improve outcomes.

In-hospital bleeding increases hospital stays and mortality. Prolonged mechanical ventilation and coagulopathy are known risk factors. Helicobacter pylori (H. pylori) is associated with upper gastrointestinal bleeding (UGIB), but its role in hospitalized patients remains unclear.

Despite widespread biologic use, more than 70% of patients with Crohn's disease require resectional surgery, most commonly of the terminal ileum. Gene expression and genetics of the neoterminal ileum at postoperative, surveillance colonoscopies highlight pathways of disease recurrence. Postoperative colonoscopy transcriptomes were interrogated to evaluate the hypothesis that specific molecular mechanisms contribute to recurrent Crohn's pathophysiology.

Acute pancreatitis (AP) is common and clinically complex, and persistent renal failure (PRF) is a severe complication. This study retrospectively analyzed 798 AP patients admitted within three days of onset and divided them into a PRF group (n = 111) and a non-PRF group (n = 687), comparing the characteristics of the two groups. Multivariate analysis showed that lactate (β = 0.340, P < 0.001, OR = 1.405) and lactate dehydrogenase (LDH, β = 0.002, P < 0.001, OR = 1.002) were significant risk factors for PRF. Stratified analysis indicated that patients with LDH ≥ 700 U/L and lactate ≥ 2 mmol/L had a higher incidence of PRF. The ROC curve analysis showed that the areas under the curve for lactate, LDH, and the combined lactate + LDH were 0.752, 0.828, and 0.866, respectively, with the highest diagnostic accuracy for the combined indicator. The characteristics of different risk groups showed that the incidence of PRF in the high-risk group was significantly higher than that in the low-risk group. The levels of lactate and LDH within 24 h of admission have a significant predictive effect on PRF in AP patients, which helps clinicians identify high-risk patients early and guide treatment decisions.

Indirect calorimetry (IC) is the gold standard for determining energy requirements. Resting energy expenditure (REE) equations could noninvasively estimate energy requirements in healthy individuals. Whether the published equations could accurately predict the REE of adults with nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) remains unclear. Here, we aimed to investigate the accuracy of predicted REE in patients with NAFLD and T2DM using different equations.

Slow transit constipation (STC), a subtype of functional constipation characterized by delayed colonic transit (> 72 h), imposes substantial physical and psychological burdens.