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621. Response by Shi and Chen to Letter Regarding Article, "Partnership Model of Regionalized Care for Congenital Heart Disease in Resource-Limited Settings: Results From the ASSIST Project".623. Correction to: Abstract Sun602: Lower Survival After Out-of- Hospital Cardiac Arrest in Older Females: The Joint Effect of Age and Sex.
作者: Emad Awad.;Brian Grunau.;Jim Christenson.;Lamis Alamoudi.;Karen Humphries.;Jennie Helmer.
来源: Circulation. 2026年153卷9期e907页 628. Aortic and Iliac Calcifications as Predictors of Aortic Dissection, Aneurysm Rupture, and Peripheral Vascular Disease: A Prospective Cohort Study from the DANCAVAS Trials.
作者: Cecilie Skov Petersen.;Zuzanna Karon.;Lasse M Obel.;Selma Hasific.;Anna Mejldal.;Lytfi Krasniqi.;Mie Schæffer.;Flemming H Steffensen.;Lars Frost.;Jess Lambrechtsen.;Martin Busk.;Grazina Urbonaviciene.;Kenneth Egstrup.;Marek Karon.;Lars M Rasmussen.;Jes S Lindholt.;Axel C P Diederichsen.
来源: Circulation. 2026年153卷14期1026-1037页
There is limited evidence of the relationship between aortic and iliac calcification and aortic events (aortic dissection or aneurysm rupture) and major adverse limb events (MALEs; peripheral revascularization and lower limb amputation). The aim of this population-based prospective cohort study was to investigate the association of aortic and iliac calcifications with aortic events and MALEs.
629. PAM-VT 2 Study: Long-Term Scar Evolution and Ablation Lesion Assessment by Late Gadolinium Enhancement Cardiac Magnetic Resonance After Ventricular Tachycardia Ablation.
作者: Ivo Roca-Luque.;Paz Garre.;Sara Vázquez-Calvo.;José Tomás Ortiz-Pérez.;Susana Prat-González.;Rosario Jesús Perea.;Pasquale Valerio Falzone.;Jean-Baptiste Guichard.;Mariona Regany-Closa.;Till F Althoff.;Eduard Guasch.;Jose María Tolosana.;Elena Arbelo.;Paula Sánchez-Somonte.;Levio Quinto.;Roger Borràs.;Rebeca Domingo.;Mireia Niebla.;Ana García-Alvarez.;Marta Sitges.;Josep Brugada.;Lluís Mont.;Andreu Porta-Sánchez.
来源: Circulation. 2026年153卷12期874-886页
Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) is useful for identifying ventricular tachycardia (VT) substrate in patients with structural heart disease. While preprocedural LGE-CMR is widely used for planning, the role of postprocedural LGE-CMR in evaluating VT ablation success and long-term scar evolution has been less explored. This study aimed to prospectively and systematically assess the long-term evolution of scar and ablation lesions using serial postablation LGE-CMR with long-term follow-up.
630. Shocking Practices of Pediatric Electrophysiologists: Contemporary Defibrillation Testing Data From a Multicenter National CIED Registry.
作者: Iqbal El-Assaad.;Benjamin H Hammond.;Bradley C Clark.;Ronn E Tanel.;Anne M Dubin.;Ian Law.;Bradley S Marino.;Amy Cassedy.;Elizabeth Vickers Saarel.;Maully J Shah.;Prince J Kannankeril.;Soham Dasgupta.;Douglas Y Mah.
来源: Circ Arrhythm Electrophysiol. 2026年19卷3期e014288页 631. MUTTON-HF: Rationale and Design of a Study of an Indigenous Food is Medicine Intervention.
作者: Lauren A Eberly.;Carmen George.;Sharon Sandman.;Denee Bex.;Karianne Jones.;Asia Yazzie.;Leah Gray.;Larissa Morgan.;Ada Tennison.;Conor Williams.;Matt Chandra.;Rebecca Wickre.;Bennett Wickre.;Mackenzie Bolas.;Remi Welbel.;Delaney Ignace.;Benjamin Feliciano.;DezBaa Damon-Mallette.;Erica Lindsey.;Paula Mora.;Maricruz Merino.;Enrique F Schisterman.;Sonya S Shin.
来源: Circ Heart Fail. 2026年19卷4期e014013页
Nutrition insecurity is a major driver of poor cardiovascular health in Indigenous communities. Medically tailored meals may improve heart failure outcomes and quality of life. There is growing momentum among Indigenous communities to reclaim traditional precontact foods to improve cardiovascular health. In this context, utilizing community-based-participatory methods, we designed MUTTON-HF (Medically Utilized Tailored Traditional Foods to Optimize Nutrition in Heart Failure)-an Indigenous culturally and medically tailored meals program that locally sources Native produce and meat and incorporates traditional Diné (Navajo) foods and recipes.
632. Small Extracellular Vesicle External Surface Adiponectin-Mediated Adipocytes/Cardiomyocytes Communication in Diabetic Ischemic Heart Failure.
作者: Zhen Zhang.;Di Zhu.;Caihong Liu.;Lu Gan.;Jianli Zhao.;Zhijun Meng.;Peng Yao.;Demin Liu.;Guoqiang Gu.;Bernard Lopez.;Theodore A Christopher.;Yajing Wang.;Xinliang Ma.
来源: Circulation. 2026年
Mortality from acute myocardial infarction (MI) has declined significantly in the past decade for nondiabetic patients. However, both morbidity and mobility of ischemic heart failure (IHF) persistently escalate in the diabetic population via incompletely understood mechanisms. Recent studies demonstrated that small extracellular vesicles (sEVs) released from nondiabetic and diabetic adipocytes (ADps) exert opposite effects on acute myocardial ischemia and reperfusion (MI/R) injury. However, whether and how ADp sEVs may protect against post-MI remodeling and IHF, and more important, whether and how diabetes may impair this protective effect, remain unknown.
633. P16+ Cells Drive Adverse Postischemic Cardiac Remodeling Through CCL8-Mediated Recruitment of Cytotoxic Lymphocytes.
作者: Lei Yan.;Jialei Zheng.;Zhengkai Lu.;Anqi Zhu.;Min Ye.;Jufeng Meng.;Juan Tang.;Hui Zhang.
来源: Circulation. 2026年
Ischemic heart disease remains a leading cause of mortality worldwide, with adverse remodeling after myocardial infarction driven by inflammation and cardiomyocyte loss. Although cytotoxic lymphocytes exacerbate myocardial injury and P16 marks cellular senescence in diseased hearts, the cell type-specific functions of P16+ populations remain unclear.
634. Low-Dose Rivaroxaban Plus Aspirin in Patients With PAD Undergoing Lower Extremity Revascularization With and Without History of Prior Limb Revascularization: Insight From the VOYAGER-PAD Trial.
作者: Mario Enrico Canonico.;Jessica Parr.;E Sebastian Debus.;Mark R Nehler.;Manesh R Patel.;Sonia S Anand.;Mark Svet.;Connie N Hess.;Warren H Capell.;Joseph Ycas.;Julian Chen.;Michael Szarek.;Eva Muehlhofer.;Lloyd P Haskell.;Scott D Berkowitz.;Rupert M Bauersachs.;Marc P Bonaca.
来源: Circ Cardiovasc Interv. 2026年19卷5期e015229页
Patients with peripheral artery disease (PAD) undergoing lower extremity revascularization (LER) are at high risk of major adverse limb events (MALE) and major adverse cardiovascular events. The VOYAGER-PAD trial (Vascular Outcomes Study of Acetylsalicylic Acid Along With Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery Disease) demonstrated that rivaroxaban 2.5 mg twice daily on top of antiplatelet therapy significantly reduced this risk. Whether the risk of major adverse cardiovascular events and MALE and the effect of rivaroxaban are consistent in patients with a history of prior LER versus those without has not been described.
635. NURSE-Led Care in Patients Undergoing Catheter Ablation for Atrial Fibrillation: The NURSECAT-AF Randomized Trial.
作者: Alba Cano-Valls.;Maria Antonia Martinez Monblan.;Esther Carro-Fernández.;Mireia Niebla.;Rebeca Domingo.;Sara Hevia-Puyo.;Montserrat Venturas-Nieto.;Roger Borras.;José María Tolosana.;Andreu Porta-Sánchez.;Jean-Baptiste Guichard.;Till F Althoff.;Ivo Roca-Luque.;Lluis Mont.;Eduard Guasch.
来源: Circ Arrhythm Electrophysiol. 2026年19卷3期e014149页
Atrial fibrillation (AF) is associated with reduced quality of life and frequent hospitalizations. Integrated nurse-led care (NLC) has proven beneficial in unselected AF patients, but evidence specific to patients undergoing catheter ablation is limited. We aimed to assess the impact of a structured nurse-led intervention in patients undergoing first-time AF ablation.
636. Long-Term Stability of a Coronary-Encasing Cardiac Paraganglioma: A 4-Year Multimodality Imaging Follow-Up.
作者: Huaijun Wang.;Mary P Watkins.;Anne H Atteberry.;Joshua D Mitchell.;Mustafa Husani.;Jasvindar Singh.;Gregory M Lanza.
来源: Circ Cardiovasc Imaging. 2026年19卷4期e018923页 637. Genotype-Guided P2Y12-Inhibitor De-Escalation Strategy in Acute Coronary Syndrome: Observational Evidence From the POPular-GUIDE PCI.
作者: Wout W A van den Broek.;Jaouad Azzahhafi.;Qiu Ying F van de Pol.;Dean R P P Chan Pin Yin.;Niels M R van der Sangen.;Shabiga Sivanesan.;J Peper.;Ankie M Harmsze.;Ronald J Walhout.;Melvyn Tjon Joe Gin.;Nicoline J Breet.;Jorina Langerveld.;Yolande Appelman.;Ron H N van Schaik.;José P S Henriques.;Wouter J Kikkert.;Jurriën M Ten Berg.
来源: Circ Cardiovasc Interv. 2026年19卷5期e016084页
A genotype-guided de-escalation strategy-switching from a potent P2Y12 inhibitor to clopidogrel-may reduce bleeding risk in patients with acute coronary syndrome. This analysis evaluated the safety and effectiveness of routine genetic testing to guide antiplatelet therapy in clinical practice.
638. Right and Left Atrial Dysfunction as Independent Cardiovascular Risk Factors: A UK Biobank Study.
作者: Vidhushei Yogeswaran.;Jennifer A Brody.;Colleen M Sitlani.;Kerri L Wiggins.;Jordan M Prutkin.;Joshua C Bis.;Eugene Yang.;Amil M Shah.;Nazem Akoum.;Ting Ye.;James S Floyd.
来源: Circ Arrhythm Electrophysiol. 2026年19卷3期e014412页
Atrial cardiopathy often precedes atrial fibrillation (AF) and has emerged as an independent risk factor for cardiovascular outcomes. However, previous studies have been limited in size and have overlooked the right atrium.
639. Impact of Catheter Configuration on the Mapping of Atrial Fibrillation.
作者: Miguel Rodrigo.;Samuel Ruipérez-Campillo.;Prasanth Ganesan.;Ruibin Feng.;Sanjiv M Narayan.
来源: Circ Arrhythm Electrophysiol. 2026年19卷3期e014061页
Mapping of heart rhythms is influenced by the size and configuration of the mapping electrodes. Whether a recorded electrogram represents near (local) or remote activity influences diagnosis and treatment, yet is affected by mapping characteristics that are often undefined.
640. Predictors of Favorable Neurological Outcomes Following Atrioesophageal Fistula After Radiofrequency Catheter Ablation for Atrial Fibrillation: A Subanalysis of the POTTER-AF Study.
作者: Kohei Ukita.;Sorin Stefan Popescu.;Vanessa Schmidt.;Helmut Pürerfellner.;Philipp Sommer.;Christian Sohns.;Christian Veltmann.;Daniel Steven.;K R Julian Chun.;Philippe Maury.;Estelle Gandjbakhch.;Stephan Willems.;Thomas Beiert.;Leon Iden.;Anna Füting.;Raphael Spittler.;Sergio Richter.;Anja Schade.;Malte Kuniss.;Carsten Wunderlich.;Dong-In Shin.;Dirk Grosse Meininghaus.;Marc Bonsels.;David Reek.;Uwe Wiegand.;Alexander Bauer.;Andreas Metzner.;Lars Eckardt.;Olaf Krahnefeld.;Christian Sticherling.;Michael Kühne.;Dinh Quang Nguyen.;Laurent Roten.;Dominik Linz.;Pepijn van der Voort.;Bart A Mulder.;Johan Vijgen.;Alexandre Almorad.;Charles Guenancia.;Laurent Fauchier.;Serge Boveda.;Yves De Greef.;Antoine Da Costa.;Pierre Jais.;Antoine Milhem.;Laurence Jesel.;Rodrigue Garcia.;Hervé Poty.;Ziad Khoueiry.;Julien Seitz.;Julien Laborderie.;Alexis Mechulan.;Francois Brigadeau.;Alexandre Zhao.;Yannick Saludas.;Olivier Piot.;Nikhil Ahluwalia.;Claire A Martin.;Jian Chen.;Bor Antolic.;Georgios Leventopoulos.;Emin Evren Özcan.;Hikmet Yorgun.;Serkan Cay.;Kivanc Yalin.;Maichel Sobhy Botros.;Ewa Jędrzejczyk-Patej.;Osamu Inaba.;Ken Okumura.;Koichiro Ejima.;Houman Khakpour.;John N Catanzaro.;Vivek Reddy.;Andrea Natale.;Hermann Blessberger.;Bing Yang.;Julia Vogler.;Karl-Heinz Kuck.;José Luis Merino.;Ardan M Saguner.;Ahmad Keelani.;Christian-H Heeger.;Roland Richard Tilz.; .
来源: Circ Arrhythm Electrophysiol. 2026年19卷3期e014579页 |