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41. Impact of mepolizumab on the AAV-PRO questionnaire in eosinophilic granulomatosis with polyangiitis: data from a European multicentre study.
作者: Paolo Delvino.;Luca Quartuccio.;Joanna C Robson.;Virginia V Ferretti.;Catherine Klersy.;Federico Alberici.;Diego Bagnasco.;Alvise Berti.;Marco Caminati.;Marta Camoni.;Maria C Cid.;Edoardo Conticini.;Giulia Costanzo.;Claire de Moreuil.;Stefano Del Giacco.;Georgina Espigol-Frigole.;Franco Franceschini.;Luca Iorio.;Anna Kernder.;Alberto Lo Gullo.;Laura Losappio.;Elena Manna.;Matteo Maule.;Alessandra Milanesi.;Carlomaurizio Montecucco.;Simone Negrini.;Roberto Padoan.;Francesca Regola.;Luisa Ricciardi.;Jan Schroeder.;Benjamin Terrier.;Paola Toniati.;Francesca Torracca.;Elena Treppo.;Maria Letizia Urban.;Augusto Vaglio.;Giacomo Emmi.;Sara Monti.
来源: Rheumatology (Oxford). 2025年
To prospectively evaluate the impact and the rapidity of the effect of mepolizumab on the ANCA-associated vasculitis patient-reported outcomes (AAV-PRO) questionnaire and patient global assessment (PtGA) in an international, multicentre cohort of patients with eosinophilic granulomatosis with polyangiitis (EGPA).
43. Plasma C4d levels correlate with treatment response and renal activity in proliferative lupus nephritis.
作者: Agneta Zickert.;Caroline Grönwall.;Anna Juto.;Lina-Marcela Diaz-Gallo.;Sepehr Sarrafzadeh Zargar.;Ann Mongan.;Henk-Andre Kroon.;Myriam Martin.;Anna M Blom.;Edmund Chang.;Iva Gunnarsson.
来源: Rheumatology (Oxford). 2025年
Investigation of complement factors in lupus nephritis (LN) in relation to treatment response and the impact of underlying genetics of C4.
44. Indications, efficacy, safety of rituximab in childhood-onset systemic lupus erythematosus: a retrospective study of the JIR cohort.
作者: Jade Cognard.;Christine Pietrement.;Audrey Laurent.;Marine Fouillet-Desjonquères.;Patricia Moran-Alvarez.;Héloïse Reumaux.;Damia Leguevaques.;Yves Hatchuel.;Arthur Felix.;Pascal Pillet.;Charlotte Rebelle.;Diego Urbina.;Pierre Quartier-Dit-Maire.;Isabelle Melki.;Florence A Aeschlimann.;Isabelle Koné-Paut.;Linda Rossi-Semerano.;Micheline Pha.;Michaël Hofer.;Samira Plassart.;Brigitte Bader-Meunier.;Alexandre Belot.
来源: Rheumatology (Oxford). 2025年
Childhood-onset systemic lupus erythematosus (cSLE) is a rare autoimmune disease with significant morbidity. Although B cell-depleting agents show promise for refractory cSLE, there is limited research on Rituximab therapy in children. This study aimed to retrospectively assess the indications, efficacy, and safety of RTX in cSLE, using data from the Juvenile Inflammatory Rheumatism (JIR) cohort database.
45. What is the economic burden of delayed axial spondyloarthritis diagnosis in the UK?
作者: Fernando Zanghelini.;George Xydopoulos.;Stephanie Howard Wilsher.;Oyewumi Afolabi.;Dale Webb.;Joe Eddison.;Thomas A Ingram.;Clare Clark.;Jill Hamilton.;Raj Sengupta.;Karl Gaffney.;Richard Fordham.
来源: Rheumatology (Oxford). 2025年
To develop an economic model to determine the annual cost of delayed axial spondyloarthritis (axial SpA) diagnosis in the UK, adopting both National Health Service (NHS) and societal perspectives.
46. Kynurenines and neopterin are interferon-gamma-inducible biomarkers for Sjögren's disease.
作者: Valéria Valim.;Fabíola R Oliveira.;Samira T Miyamoto.;Érica V Serrano.;Gabriela M Balarini.;Leandro A Tanure.;Gilda A Ferreira.;Eliana Zandonade.;Johan G Brun.;Malin Jonsson.;Elisabeth Maeland.;Arve Ulvik.;Per Magne Ueland.;Roland Jonsson.;Piotr M Mydel.
来源: Rheumatology (Oxford). 2025年
The aim was to investigate whether kynurenine pathway metabolites and neopterin increase probability for Sjögren's disease (SjD) and their associations with clinical parameters and inflammatory biomarkers.
47. Incidence and prevalence of Behçet's disease in Oslo Norway: a two-decade population-based analysis.
作者: Jing Lisa Li Lorentsen.;Cathrine Brunborg.;Anders T Aasebø.;Jørgen Valeur.;Espen A Haavardsholm.;Øyvind Molberg.;Øyvind Palm.;Karoline Lerang.
来源: Rheumatology (Oxford). 2025年
To estimate the incidence and prevalence of Behçet's disease (BD) in Oslo, Norway from 1999 to 2021.
48. Short Form-36 psychometric properties in idiopathic inflammatory myopathies: reliability, validity, and responsiveness.
作者: Shiri Keret.;Anushka Aggarwal.;Maha Almackenzie.;Tissa Bijoy George.;Shreya Sriram.;Tanya Chandra.;Raisa Lomanto Silva.;Eugenia Gkiaouraki.;Nantakarn Pongtarakulpanit.;Siamak Moghadam-Kia.;Chester V Oddis.;Rohit Aggarwal.
来源: Rheumatology (Oxford). 2025年
To evaluate the psychometric properties of Short Form-36 (SF-36) as a health-related quality of life (HRQoL) measure in idiopathic inflammatory myopathies (IIM).
49. Abatacept for the treatment of myositis-associated interstitial lung disease (ATtackMy-ILD).
作者: Rohit Aggarwal.;Nantakarn Pongtarakulpanit.;Daniel I Sullivan.;Siamak Moghadam-Kia.;Sangmee Sharon Bae.;Jesse Wilkerson.;Didem Saygin.;Galina Marder.;Swamy Venuturupalli.;Paul F Dellaripa.;Sonye K Danoff.;Tracy Doyle.;Gary M Hunninghake.;Joyce S Lee.;Aryeh Fischer.;Jeremy Falk.;Cheilonda Johnson.;Diane Koontz.;Dana P Ascherman.;Chester V Oddis.
来源: Rheumatology (Oxford). 2025年
This randomized, placebo-controlled pilot trial evaluated the efficacy and safety of abatacept in patients with anti-synthetase syndrome-associated interstitial lung disease (ASyS-ILD).
50. Type I interferon dysregulation drives distinct pathogenic pathways in early- and late-onset lupus nephritis.
作者: Kunihiro Ichinose.;Hiroko Hagiwara.;Mineaki Kitamura.;Tomoya Nishino.;Atsushi Kawakami.
来源: Rheumatology (Oxford). 2025年
Lupus nephritis (LN) is a leading cause of morbidity and mortality in systemic lupus erythematosus (SLE), affecting nearly half of the patients with SLE. Type I interferon (IFN) plays a central role in SLE and LN pathogenesis. This study explored the differential expression of type I IFN gene signatures (IFNGS) in renal tissues from early- and late-onset LN patients to uncover pathways linked to disease progression.
51. Social and healthcare professionals' work to establish coherent rehabilitation pathways for people with inflammatory arthritis: a qualitative study.
作者: Helle Feddersen.;Camilla Vestergaard Aarøe.;Jens Søndergaard.;Lena Andersen.;Bettina Munksgaard.;Jette Primdahl.
来源: BMC Rheumatol. 2025年9卷1期48页
Professionals in health and social care are challenged by the complexity and fragmentation across primary and secondary levels of care. To study coherent rehabilitation pathways, we focused on people with inflammatory arthritis admitted to a specialised rehabilitation stay as these pathways will involve a myriad of different professionals from primary and secondary levels of care. This study aimed to explore how health and social care professionals establish coherent rehabilitation pathways for people with inflammatory arthritis across primary and secondary levels of care and how organisational factors influence on workflow.
56. Diminished SUV3 expression and its functional implications in the IFN-enriched monocyte subset of childhood Sjögren's Disease.
作者: Jimin Yoon.;Daesong Jang.;Myung-Chul Kim.;Joon Paek.;Rehae Miller.;Beatriz Veronese.;Rudy Alvarado.;Akaluck Thatayatikom.;Yoosik Kim.;Seunghee Cha.
来源: Rheumatology (Oxford). 2025年
This study investigates the molecular and functional implications of reduced Suv3-like RNA helicase (SUV3) expression in the interferon (IFN)-enriched subset of monocytes from childhood Sjögren's disease (cSjD). SUV3 is known to unwind double-stranded RNAs (dsRNAs) for homeostatic RNA decay within mitochondria.
57. Real-world care patterns and specialist encounters of patients with systemic autoimmune rheumatic disease-related interstitial lung disease in the United States: a retrospective administrative claims database analysis.
作者: Joseph Yang.;Michael A Head.;Kevin D Schott.;Hiangkiat Tan.;Rachel Djaraher.;Christopher L Crowe.;Mark Napier.;Kenneth Kossack.;Amy L Olson.;Elana J Bernstein.
来源: Rheumatology (Oxford). 2025年
We aimed to describe the demographics, clinical characteristics, and care patterns of patients with systemic autoimmune rheumatic diseases (SARD) prior to their interstitial lung disease (ILD) diagnosis.
58. Recruitment rate comparison between a virtual tele-research cohort and a traditional center-based cohort in idiopathic inflammatory myopathy.
作者: Siamak Moghadam-Kia.;Anushka Aggarwal.;Swamy Venuturupalli.;Shiri Keret.;Nantakarn Pongtarakulpanit.;Mark Riley.;Shalini Mahajan.;Daphne Scaramangas-Plumley.;Aarat Patel.;Joe Kelley.;Eleni Tiniakou.;Chester V Oddis.;Rohit Aggarwal.;MyPacer Study Group.
来源: Rheumatology (Oxford). 2025年
Idiopathic inflammatory myopathy (IIM, myositis) faces recruitment and retention challenges in clinical studies due to disease rarity, geographical barriers, and logistic difficulties. This study aimed to compare recruitment, enrolment, retention, and data completion between a decentralized telemedicine-based research cohort (TRC); and a traditional center-based cohort (CBC) in IIM.
59. A novel approach to refractory idiopathic inflammatory myopathy: CD19 CAR T-cell therapy-case report and literature review.
作者: Isabell Haase.;Johanna Richter.;Marie-Therese Holzer.;Boris Fehse.;Nikolas Ruffer.;Johan Seibel.;Susanna C Berger.;Nico Gagelmann.;Dominic Borie.;Francis Ayuk.;Ina Kötter.;Martin Krusche.;Nicolaus Kröger.
来源: Rheumatology (Oxford). 2025年
To explore efficacy and safety of CD19-directed Chimeric Antigen Receptor (CAR) T cell therapy in a patient with Jo1-Antisynthetase-syndrome (ASyS) refractory to multiple immunosuppressants, including anti-CD38 therapy, and review published cases on CAR T cell therapy in idiopathic inflammatory myopathies (IIM).
60. Arterial cardiovascular outcomes and venous thromboembolism in patients with primary Sjögren's syndrome: A Danish cohort study.
作者: Pierre Loiseau.;Aurélie Mailhac.;Pierre Duhaut.;Reimar W Thomsen.
来源: Rheumatology (Oxford). 2025年
To evaluate whether atherosclerotic cardiovascular disease outcomes, venous thromboembolism, heart failure, and cardiovascular mortality are elevated in patients with primary Sjögren's syndrome (pSS) compared with a matched cohort from the general population.
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