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41. Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma: A Systematic Review and Meta-analysis.
作者: Lisa H Y Kim.;Carol Saleh.;Anna Whalen-Browne.;Paul M O'Byrne.;Derek K Chu.
来源: JAMA. 2021年325卷24期2466-2479页
The benefits and harms of adding long-acting muscarinic antagonists (LAMAs) to inhaled corticosteroids (ICS) and long-acting β2-agonists (LABAs) for moderate to severe asthma remain unclear.
42. Screening for Hearing Loss in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
作者: Cynthia Feltner.;Ina F Wallace.;Christine E Kistler.;Manny Coker-Schwimmer.;Daniel E Jonas.
来源: JAMA. 2021年325卷12期1202-1215页
Hearing loss is common in older adults and associated with adverse health and social outcomes.
43. Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19: A Systematic Review and Meta-analysis.
作者: Perrine Janiaud.;Cathrine Axfors.;Andreas M Schmitt.;Viktoria Gloy.;Fahim Ebrahimi.;Matthias Hepprich.;Emily R Smith.;Noah A Haber.;Nina Khanna.;David Moher.;Steven N Goodman.;John P A Ioannidis.;Lars G Hemkens.
来源: JAMA. 2021年325卷12期1185-1195页
Convalescent plasma is a proposed treatment for COVID-19.
44. Association of Receipt of Palliative Care Interventions With Health Care Use, Quality of Life, and Symptom Burden Among Adults With Chronic Noncancer Illness: A Systematic Review and Meta-analysis.
作者: Kieran L Quinn.;Mohammed Shurrab.;Kevin Gitau.;Dio Kavalieratos.;Sarina R Isenberg.;Nathan M Stall.;Therese A Stukel.;Russell Goldman.;Daphne Horn.;Peter Cram.;Allan S Detsky.;Chaim M Bell.
来源: JAMA. 2020年324卷14期1439-1450页
The evidence for palliative care exists predominantly for patients with cancer. The effect of palliative care on important end-of-life outcomes in patients with noncancer illness is unclear.
45. Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis.
作者: .;Jonathan A C Sterne.;Srinivas Murthy.;Janet V Diaz.;Arthur S Slutsky.;Jesús Villar.;Derek C Angus.;Djillali Annane.;Luciano Cesar Pontes Azevedo.;Otavio Berwanger.;Alexandre B Cavalcanti.;Pierre-Francois Dequin.;Bin Du.;Jonathan Emberson.;David Fisher.;Bruno Giraudeau.;Anthony C Gordon.;Anders Granholm.;Cameron Green.;Richard Haynes.;Nicholas Heming.;Julian P T Higgins.;Peter Horby.;Peter Jüni.;Martin J Landray.;Amelie Le Gouge.;Marie Leclerc.;Wei Shen Lim.;Flávia R Machado.;Colin McArthur.;Ferhat Meziani.;Morten Hylander Møller.;Anders Perner.;Marie Warrer Petersen.;Jelena Savovic.;Bruno Tomazini.;Viviane C Veiga.;Steve Webb.;John C Marshall.
来源: JAMA. 2020年324卷13期1330-1341页
Effective therapies for patients with coronavirus disease 2019 (COVID-19) are needed, and clinical trial data have demonstrated that low-dose dexamethasone reduced mortality in hospitalized patients with COVID-19 who required respiratory support.
46. Association of Radial Artery Graft vs Saphenous Vein Graft With Long-term Cardiovascular Outcomes Among Patients Undergoing Coronary Artery Bypass Grafting: A Systematic Review and Meta-analysis.
作者: Mario Gaudino.;Umberto Benedetto.;Stephen Fremes.;Karla Ballman.;Giuseppe Biondi-Zoccai.;Art Sedrakyan.;Giuseppe Nasso.;Jai Raman.;Brian Buxton.;Philip A Hayward.;Neil Moat.;Peter Collins.;Carolyn Webb.;Miodrag Peric.;Ivana Petrovic.;Kyung J Yoo.;Irbaz Hameed.;Antonino Di Franco.;Marco Moscarelli.;Giuseppe Speziale.;John D Puskas.;Leonard N Girardi.;David L Hare.;David P Taggart.; .
来源: JAMA. 2020年324卷2期179-187页
Observational studies have suggested that the use of radial artery grafts for coronary artery bypass grafting may improve clinical outcomes compared with the use of saphenous vein grafts, but this has not been confirmed in randomized trials.
47. Accuracy of the PHQ-2 Alone and in Combination With the PHQ-9 for Screening to Detect Major Depression: Systematic Review and Meta-analysis.
作者: Brooke Levis.;Ying Sun.;Chen He.;Yin Wu.;Ankur Krishnan.;Parash Mani Bhandari.;Dipika Neupane.;Mahrukh Imran.;Eliana Brehaut.;Zelalem Negeri.;Felix H Fischer.;Andrea Benedetti.;Brett D Thombs.; .;Liying Che.;Alexander Levis.;Kira Riehm.;Nazanin Saadat.;Marleine Azar.;Danielle Rice.;Jill Boruff.;Lorie Kloda.;Pim Cuijpers.;Simon Gilbody.;John Ioannidis.;Dean McMillan.;Scott Patten.;Ian Shrier.;Roy Ziegelstein.;Ainsley Moore.;Dickens Akena.;Dagmar Amtmann.;Bruce Arroll.;Liat Ayalon.;Hamid Baradaran.;Anna Beraldi.;Charles Bernstein.;Arvin Bhana.;Charles Bombardier.;Ryna Imma Buji.;Peter Butterworth.;Gregory Carter.;Marcos Chagas.;Juliana Chan.;Lai Fong Chan.;Dixon Chibanda.;Rushina Cholera.;Kerrie Clover.;Aaron Conway.;Yeates Conwell.;Federico Daray.;Janneke de Man-van Ginkel.;Jaime Delgadillo.;Crisanto Diez-Quevedo.;Jesse Fann.;Sally Field.;Jane Fisher.;Daniel Fung.;Emily Garman.;Bizu Gelaye.;Leila Gholizadeh.;Lorna Gibson.;Felicity Goodyear-Smith.;Eric Green.;Catherine Greeno.;Brian Hall.;Petra Hampel.;Liisa Hantsoo.;Emily Haroz.;Martin Harter.;Ulrich Hegerl.;Leanne Hides.;Stevan Hobfoll.;Simone Honikman.;Marie Hudson.;Thomas Hyphantis.;Masatoshi Inagaki.;Khalida Ismail.;Hong Jin Jeon.;Nathalie Jetté.;Mohammad Khamseh.;Kim Kiely.;Sebastian Kohler.;Brandon Kohrt.;Yunxin Kwan.;Femke Lamers.;María Asunción Lara.;Holly Levin-Aspenson.;Valéria Lino.;Shen-Ing Liu.;Manote Lotrakul.;Sonia Loureiro.;Bernd Löwe.;Nagendra Luitel.;Crick Lund.;Ruth Ann Marrie.;Laura Marsh.;Brian Marx.;Anthony McGuire.;Sherina Mohd Sidik.;Tiago Munhoz.;Kumiko Muramatsu.;Juliet Nakku.;Laura Navarrete.;Flávia Osório.;Vikram Patel.;Brian Pence.;Philippe Persoons.;Inge Petersen.;Angelo Picardi.;Stephanie Pugh.;Terence Quinn.;Elmars Rancans.;Sujit Rathod.;Katrin Reuter.;Svenja Roch.;Alasdair Rooney.;Heather Rowe.;Iná Santos.;Miranda Schram.;Juwita Shaaban.;Eileen Shinn.;Abbey Sidebottom.;Adam Simning.;Lena Spangenberg.;Lesley Stafford.;Sharon Sung.;Keiko Suzuki.;Richard Swartz.;Pei Lin Lynnette Tan.;Martin Taylor-Rowan.;Thach Tran.;Alyna Turner.;Christina van der Feltz-Cornelis.;Thandi van Heyningen.;Henk van Weert.;Lynne Wagner.;Jian Li Wang.;Jennifer White.;Kirsty Winkley.;Karen Wynter.;Mitsuhiko Yamada.;Qing Zhi Zeng.;Yuying Zhang.
来源: JAMA. 2020年323卷22期2290-2300页
The Patient Health Questionnaire depression module (PHQ-9) is a 9-item self-administered instrument used for detecting depression and assessing severity of depression. The Patient Health Questionnaire-2 (PHQ-2) consists of the first 2 items of the PHQ-9 (which assess the frequency of depressed mood and anhedonia) and can be used as a first step to identify patients for evaluation with the full PHQ-9.
48. Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory Failure: A Systematic Review and Meta-analysis.
作者: Bruno L Ferreyro.;Federico Angriman.;Laveena Munshi.;Lorenzo Del Sorbo.;Niall D Ferguson.;Bram Rochwerg.;Michelle J Ryu.;Refik Saskin.;Hannah Wunsch.;Bruno R da Costa.;Damon C Scales.
来源: JAMA. 2020年324卷1期57-67页
Treatment with noninvasive oxygenation strategies such as noninvasive ventilation and high-flow nasal oxygen may be more effective than standard oxygen therapy alone in patients with acute hypoxemic respiratory failure.
49. Interventions to Prevent Illicit and Nonmedical Drug Use in Children, Adolescents, and Young Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
作者: Elizabeth O'Connor.;Rachel Thomas.;Caitlyn A Senger.;Leslie Perdue.;Shannon Robalino.;Carrie Patnode.
来源: JAMA. 2020年323卷20期2067-2079页
Illicit and nonmedical (use in ways other than instructed) drug use is common in adolescents and young adults and increases the risk of harmful outcomes such as injuries, violence, and poorer academic performance.
50. Association of Blood Pressure Lowering With Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis.
作者: Diarmaid Hughes.;Conor Judge.;Robert Murphy.;Elaine Loughlin.;Maria Costello.;William Whiteley.;Jackie Bosch.;Martin J O'Donnell.;Michelle Canavan.
来源: JAMA. 2020年323卷19期1934-1944页
The benefit of blood pressure lowering for the prevention of dementia or cognitive impairment is unclear.
51. Primary Care-Relevant Interventions for Tobacco and Nicotine Use Prevention and Cessation in Children and Adolescents: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
作者: Shelley Selph.;Carrie Patnode.;Steffani R Bailey.;Miranda Pappas.;Ryan Stoner.;Roger Chou.
来源: JAMA. 2020年323卷16期1599-1608页
Interventions to discourage the use of tobacco products (including electronic nicotine delivery systems or e-cigarettes) among children and adolescents may help decrease tobacco-related illness and injury.
52. Association of Home Noninvasive Positive Pressure Ventilation With Clinical Outcomes in Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis.
作者: Michael E Wilson.;Claudia C Dobler.;Allison S Morrow.;Bradley Beuschel.;Mouaz Alsawas.;Raed Benkhadra.;Mohamed Seisa.;Aniket Mittal.;Manuel Sanchez.;Lubna Daraz.;Steven Holets.;M Hassan Murad.;Zhen Wang.
来源: JAMA. 2020年323卷5期455-465页
The association of home noninvasive positive pressure ventilation (NIPPV) with outcomes in chronic obstructive pulmonary disease (COPD) and hypercapnia is uncertain.
53. Primary Care Screening for Abdominal Aortic Aneurysm: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
作者: Janelle M Guirguis-Blake.;Tracy L Beil.;Caitlyn A Senger.;Erin L Coppola.
来源: JAMA. 2019年322卷22期2219-2238页
Ruptured abdominal aortic aneurysms (AAAs) have mortality estimated at 81%.
54. Association of Surgical Hematoma Evacuation vs Conservative Treatment With Functional Outcome in Patients With Cerebellar Intracerebral Hemorrhage.
作者: Joji B Kuramatsu.;Alessandro Biffi.;Stefan T Gerner.;Jochen A Sembill.;Maximilian I Sprügel.;Audrey Leasure.;Lauren Sansing.;Charles Matouk.;Guido J Falcone.;Matthias Endres.;Karl Georg Haeusler.;Jan Sobesky.;Johannes Schurig.;Sarah Zweynert.;Miriam Bauer.;Peter Vajkoczy.;Peter A Ringleb.;Jan Purrucker.;Timolaos Rizos.;Jens Volkmann.;Wolfgang Müllges.;Peter Kraft.;Anna-Lena Schubert.;Frank Erbguth.;Martin Nueckel.;Peter D Schellinger.;Jörg Glahn.;Ulrich J Knappe.;Gereon R Fink.;Christian Dohmen.;Henning Stetefeld.;Anna Lena Fisse.;Jens Minnerup.;Georg Hagemann.;Florian Rakers.;Heinz Reichmann.;Hauke Schneider.;Jan Rahmig.;Albert Christian Ludolph.;Sebastian Stösser.;Hermann Neugebauer.;Joachim Röther.;Peter Michels.;Michael Schwarz.;Gernot Reimann.;Hansjörg Bäzner.;Henning Schwert.;Joseph Claßen.;Dominik Michalski.;Armin Grau.;Frederick Palm.;Christian Urbanek.;Johannes C Wöhrle.;Fahid Alshammari.;Markus Horn.;Dirk Bahner.;Otto W Witte.;Albrecht Günther.;Gerhard F Hamann.;Manuel Hagen.;Sebastian S Roeder.;Hannes Lücking.;Arnd Dörfler.;Fernando D Testai.;Daniel Woo.;Stefan Schwab.;Kevin N Sheth.;Hagen B Huttner.
来源: JAMA. 2019年322卷14期1392-1403页
The association of surgical hematoma evacuation with clinical outcomes in patients with cerebellar intracerebral hemorrhage (ICH) has not been established.
55. Association of General Anesthesia vs Procedural Sedation With Functional Outcome Among Patients With Acute Ischemic Stroke Undergoing Thrombectomy: A Systematic Review and Meta-analysis.
作者: Silvia Schönenberger.;Pia Löwhagen Hendén.;Claus Z Simonsen.;Lorenz Uhlmann.;Christina Klose.;Johannes A R Pfaff.;Albert J Yoo.;Leif H Sørensen.;Peter A Ringleb.;Wolfgang Wick.;Meinhard Kieser.;Markus A Möhlenbruch.;Mads Rasmussen.;Alexandros Rentzos.;Julian Bösel.
来源: JAMA. 2019年322卷13期1283-1293页
General anesthesia during thrombectomy for acute ischemic stroke has been associated with poor neurological outcome in nonrandomized studies. Three single-center randomized trials reported no significantly different or improved outcomes for patients who received general anesthesia compared with procedural sedation.
56. Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis.
作者: .;T I M Korevaar.;Arash Derakhshan.;Peter N Taylor.;Marcel Meima.;Liangmiao Chen.;Sofie Bliddal.;David M Carty.;Margreet Meems.;Bijay Vaidya.;Beverley Shields.;Farkhanda Ghafoor.;Polina V Popova.;Lorena Mosso.;Emily Oken.;Eila Suvanto.;Aya Hisada.;Jun Yoshinaga.;Suzanne J Brown.;Judit Bassols.;Juha Auvinen.;Wichor M Bramer.;Abel López-Bermejo.;Colin Dayan.;Laura Boucai.;Marina Vafeiadi.;Elena N Grineva.;Alexandra S Tkachuck.;Victor J M Pop.;T G Vrijkotte.;M Guxens.;L Chatzi.;J Sunyer.;A Jiménez-Zabala.;I Riaño.;M Murcia.;X Lu.;S Mukhtar.;C Delles.;U Feldt-Rasmussen.;S M Nelson.;E K Alexander.;L Chaker.;T Männistö.;J P Walsh.;E N Pearce.;E A P Steegers.;R P Peeters.
来源: JAMA. 2019年322卷7期632-641页
Maternal hypothyroidism and hyperthyroidism are risk factors for preterm birth. Milder thyroid function test abnormalities and thyroid autoimmunity are more prevalent, but it remains controversial if these are associated with preterm birth.
57. Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes.
作者: .;Ellis Voerman.;Susana Santos.;Hazel Inskip.;Pilar Amiano.;Henrique Barros.;Marie-Aline Charles.;Leda Chatzi.;George P Chrousos.;Eva Corpeleijn.;Sarah Crozier.;Myriam Doyon.;Merete Eggesbø.;Maria Pia Fantini.;Sara Farchi.;Francesco Forastiere.;Vagelis Georgiu.;Davide Gori.;Wojciech Hanke.;Irva Hertz-Picciotto.;Barbara Heude.;Marie-France Hivert.;Daniel Hryhorczuk.;Carmen Iñiguez.;Anne M Karvonen.;Leanne K Küpers.;Hanna Lagström.;Debbie A Lawlor.;Irina Lehmann.;Per Magnus.;Renata Majewska.;Johanna Mäkelä.;Yannis Manios.;Monique Mommers.;Camilla S Morgen.;George Moschonis.;Ellen A Nohr.;Anne-Marie Nybo Andersen.;Emily Oken.;Agnieszka Pac.;Eleni Papadopoulou.;Juha Pekkanen.;Costanza Pizzi.;Kinga Polanska.;Daniela Porta.;Lorenzo Richiardi.;Sheryl L Rifas-Shiman.;Nel Roeleveld.;Luca Ronfani.;Ana C Santos.;Marie Standl.;Hein Stigum.;Camilla Stoltenberg.;Elisabeth Thiering.;Carel Thijs.;Maties Torrent.;Tomas Trnovec.;Marleen M H J van Gelder.;Lenie van Rossem.;Andrea von Berg.;Martine Vrijheid.;Alet Wijga.;Oleksandr Zvinchuk.;Thorkild I A Sørensen.;Keith Godfrey.;Vincent W V Jaddoe.;Romy Gaillard.
来源: JAMA. 2019年321卷17期1702-1715页
Both low and high gestational weight gain have been associated with adverse maternal and infant outcomes, but optimal gestational weight gain remains uncertain and not well defined for all prepregnancy weight ranges.
58. Will This Patient Be Difficult to Intubate?: The Rational Clinical Examination Systematic Review.
作者: Michael E Detsky.;Naheed Jivraj.;Neill K Adhikari.;Jan O Friedrich.;Ruxandra Pinto.;David L Simel.;Duminda N Wijeysundera.;Damon C Scales.
来源: JAMA. 2019年321卷5期493-503页
Recognizing patients in whom endotracheal intubation is likely to be difficult can help alert physicians to the need for assistance from a clinician with airway training and having advanced airway management equipment available.
59. Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis.
The role for aspirin in cardiovascular primary prevention remains controversial, with potential benefits limited by an increased bleeding risk.
60. Association of Pharmacological Treatments With Long-term Pain Control in Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis.
作者: Dario Gregori.;Giampaolo Giacovelli.;Clara Minto.;Beatrice Barbetta.;Francesca Gualtieri.;Danila Azzolina.;Paola Vaghi.;Lucio C Rovati.
来源: JAMA. 2018年320卷24期2564-2579页
Even though osteoarthritis is a chronic and progressive disease, pharmacological agents are mainly studied over short-term periods, resulting in unclear recommendations for long-term disease management.
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