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561. Administration of neutral protamine Hagedorn insulin at bedtime versus with dinner in type 1 diabetes mellitus to avoid nocturnal hypoglycemia and improve control. A randomized, controlled trial.
作者: Carmine G Fanelli.;Simone Pampanelli.;Francesca Porcellati.;Paolo Rossetti.;Paolo Brunetti.;Geremia B Bolli.
来源: Ann Intern Med. 2002年136卷7期504-14页
Intensive insulin treatment of type 1 diabetes mellitus increases the risk for nocturnal hypoglycemia.
563. Efficacy of resident training in smoking cessation: a randomized, controlled trial of a program based on application of behavioral theory and practice with standardized patients.
作者: Jacques Cornuz.;Jean-Paul Humair.;Laurence Seematter.;Rebecca Stoianov.;Guy van Melle.;Hans Stalder.;Alain Pécoud.
来源: Ann Intern Med. 2002年136卷6期429-37页
New educational programs must be developed to improve physicians' skills and effectiveness in counseling patients about smoking cessation.
566. Recovery rate and prognosis in older persons who develop acute lung injury and the acute respiratory distress syndrome.
作者: E Wesley Ely.;Arthur P Wheeler.;B Taylor Thompson.;Marek Ancukiewicz.;Kenneth P Steinberg.;Gordon R Bernard.
来源: Ann Intern Med. 2002年136卷1期25-36页
The incidence of acute respiratory failure requiring mechanical ventilation increases 10-fold from the ages of 55 to 85 years, yet the rate of recovery and outcomes in older persons who develop acute lung injury are poorly defined.
567. Low-dose prednisone therapy for patients with early active rheumatoid arthritis: clinical efficacy, disease-modifying properties, and side effects: a randomized, double-blind, placebo-controlled clinical trial.
作者: Amalia A van Everdingen.;Johannes W G Jacobs.;Dirk R Siewertsz Van Reesema.;Johannes W J Bijlsma.
来源: Ann Intern Med. 2002年136卷1期1-12页
Oral glucocorticoids combined with disease-modifying antirheumatic drugs are beneficial and retard radiologic joint damage in rheumatoid arthritis.
570. Effects of diet and sodium intake on blood pressure: subgroup analysis of the DASH-sodium trial.
作者: W M Vollmer.;F M Sacks.;J Ard.;L J Appel.;G A Bray.;D G Simons-Morton.;P R Conlin.;L P Svetkey.;T P Erlinger.;T J Moore.;N Karanja.; .
来源: Ann Intern Med. 2001年135卷12期1019-28页
Initial findings from the Dietary Approaches to Stop Hypertension (DASH)-Sodium Trial demonstrated that reduction of sodium intake in two different diets decreased blood pressure in participants with and without hypertension.
571. Resistance training to counteract the catabolism of a low-protein diet in patients with chronic renal insufficiency. A randomized, controlled trial.
作者: C Castaneda.;P L Gordon.;K L Uhlin.;A S Levey.;J J Kehayias.;J T Dwyer.;R A Fielding.;R Roubenoff.;M F Singh.
来源: Ann Intern Med. 2001年135卷11期965-76页
Chronic renal insufficiency leads to muscle wasting, which may be exacerbated by low-protein diets prescribed to delay disease progression. Resistance training increases protein utilization and muscle mass.
572. Predictors of virologic and clinical outcomes in HIV-1-infected patients receiving concurrent treatment with indinavir, zidovudine, and lamivudine. AIDS Clinical Trials Group Protocol 320.
作者: L M Demeter.;M D Hughes.;R W Coombs.;J B Jackson.;J M Grimes.;R J Bosch.;S A Fiscus.;S A Spector.;K E Squires.;M A Fischl.;S M Hammer.
来源: Ann Intern Med. 2001年135卷11期954-64页
A substantial proportion of patients with HIV infection will not respond to antiretroviral therapy. Early predictors of response to treatment are needed to identify patients who are at risk for treatment failure.
573. Estrogen in the prevention of atherosclerosis. A randomized, double-blind, placebo-controlled trial.
作者: H N Hodis.;W J Mack.;R A Lobo.;D Shoupe.;A Sevanian.;P R Mahrer.;R H Selzer.;C R Liu Cr.;C H Liu Ch.;S P Azen.; .
来源: Ann Intern Med. 2001年135卷11期939-53页
Although observational studies suggest that estrogen replacement therapy (ERT) reduces cardiovascular morbidity and mortality in postmenopausal women, use of unopposed ERT for prevention of coronary heart disease in healthy postmenopausal women remains untested.
574. Effect of estrogen plus progestin on risk for biliary tract surgery in postmenopausal women with coronary artery disease. The Heart and Estrogen/progestin Replacement Study.
作者: J A Simon.;D B Hunninghake.;S K Agarwal.;F Lin.;J A Cauley.;C C Ireland.;J H Pickar.
来源: Ann Intern Med. 2001年135卷7期493-501页
Animal and observational epidemiologic studies have reported that estrogens may increase the risk for gallstones. No major clinical trials have examined the effect of estrogen plus progestin therapy in postmenopausal women on the risk for biliary tract surgery.
576. Sustained-release bupropion for pharmacologic relapse prevention after smoking cessation. a randomized, controlled trial.
作者: J T Hays.;R D Hurt.;N A Rigotti.;R Niaura.;D Gonzales.;M J Durcan.;D P Sachs.;T D Wolter.;A S Buist.;J A Johnston.;J D White.
来源: Ann Intern Med. 2001年135卷6期423-33页
Smoking relapse is common after successful pharmacologic treatment for smoking cessation. No previous studies have examined long-term drug therapy used expressly for prevention of smoking relapse.
577. Intravenous and oral itraconazole versus intravenous amphotericin B deoxycholate as empirical antifungal therapy for persistent fever in neutropenic patients with cancer who are receiving broad-spectrum antibacterial therapy. A randomized, controlled trial.
作者: M Boogaerts.;D J Winston.;E J Bow.;G Garber.;A C Reboli.;A P Schwarer.;N Novitzky.;A Boehme.;E Chwetzoff.;K De Beule.; .
来源: Ann Intern Med. 2001年135卷6期412-22页
Amphotericin B deoxycholate is currently the standard empirical antifungal therapy in neutropenic patients with cancer who have persistent fever that does not respond to antibiotic therapy. However, this treatment often causes infusion-related and metabolic toxicities, which may be dose limiting.
578. Combination therapy with pulse cyclophosphamide plus pulse methylprednisolone improves long-term renal outcome without adding toxicity in patients with lupus nephritis.
作者: G G Illei.;H A Austin.;M Crane.;L Collins.;M F Gourley.;C H Yarboro.;E M Vaughan.;T Kuroiwa.;C L Danning.;A D Steinberg.;J H Klippel.;J E Balow.;D T Boumpas.
来源: Ann Intern Med. 2001年135卷4期248-57页
Controlled trials in lupus nephritis have demonstrated that cyclophosphamide therapy is superior to corticosteroid therapy alone. The long-term effectiveness and side-effect profiles of pulse immunosuppressive regimens warrant further study.
579. The effect of two different dosages of intravenous immunoglobulin on the incidence of recurrent infections in patients with primary hypogammaglobulinemia. A randomized, double-blind, multicenter crossover trial.
作者: H W Eijkhout.;J W van Der Meer.;C G Kallenberg.;R S Weening.;J T van Dissel.;L A Sanders.;P F Strengers.;H Nienhuis.;P T Schellekens.; .
来源: Ann Intern Med. 2001年135卷3期165-74页
In patients with hypogammaglobulinemia, substitution with immunoglobulin is the treatment of choice to reduce both frequency and severity of bacterial infections. Even with treatment, however, infections still occur in these patients.
580. Highly active antiretroviral therapy decreases mortality and morbidity in patients with advanced HIV disease.
作者: E L Murphy.;A C Collier.;L A Kalish.;S F Assmann.;M F Para.;T P Flanigan.;P N Kumar.;L Mintz.;F R Wallach.;G J Nemo.; .
来源: Ann Intern Med. 2001年135卷1期17-26页
Mortality and morbidity related to AIDS have decreased among HIV-infected patients taking highly active anti-retroviral therapy (HAART), but previous studies may have been confounded by other changes in treatment.
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