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543. Assessing the relation between systemic lupus erythematosus and metabolic syndrome in Syria: a cross-sectional study.
作者: Noura Mallouhi.;Ahmad Nabil Alhouri.;Naram Khalayli.;Hasan Nabil Alhouri.;Mayssoun Kudsi.;Younes Kabalan.
来源: BMC Rheumatol. 2025年9卷1期2页
Systemic Lupus Erythematosus (SLE) affects all organ systems. As a result, fat intake and sedentary life are evident in the modern world. The prevalence of metabolic syndrome, with its components, increased, leading to increased mortality. We aimed to investigate the prevalence of metabolic syndrome in SLE and its relationship with disease activity.
544. Variability of Psoriatic Arthritis Impact of Disease questionnaire (PsAID12) thresholds in psoriatic arthritis: data from the ReFlaP study.
作者: Clementina López-Medina.;Clémence Gorlier.;Ana-Maria Orbai.;Laura C Coates.;Uta Kiltz.;Ying-Ying Leung.;Penelope Palominos.;Juan D Cañete.;Rossana Scrivo.;Andra Balanescu.;Emmanuelle Dernis.;Sandra Meisalu.;Adeline Ruyssen-Witrand.;Martin Soubrier.;Sibel Zehra Aydin.;Lihi Eder.;Inna Gaydukova.;Ennio Lubrano.;Umut Kalyoncu.;Pascal Richette.;M Elaine Husni.;Josef S Smolen.;Maarten de Wit.;Laure Gossec.
来源: Rheumatology (Oxford). 2025年64卷5期3090-3094页
To explore thresholds for the Psoriatic Arthritis (PsA) Impact of Disease questionnaire (PsAID12) score against disease activity measures in an observational setting, in patients with PsA.
545. Tocilizumab and rituximab for systemic sclerosis interstitial lung disease: a real-world cohort analysis.
作者: Nina R Goldman.;Svetlana I Nihtyanova.;Claire F Beesley.;Athol U Wells.;Christopher P Denton.;Elisabetta A Renzoni.;Rizgar Mageed.;Voon H Ong.
来源: Rheumatology (Oxford). 2025年64卷SI期SI184-SI189页
SSc-interstitial lung disease (ILD) is one of the leading causes of mortality in SSc. Data from randomized controlled trials (RCTs) support rituximab and tocilizumab monotherapy but there are limited data regarding their use for those who fail standard immunomodulatory therapies.
546. Association between red blood cell distribution width and genetic risk in patients with rheumatoid arthritis: a prospective cohort study and Mendelian randomization analysis.
作者: Mingyang Chen.;Jing Lei.;Zhenqiu Liu.;Renjia Zhao.;Yanfeng Jiang.;Kelin Xu.;Tiejun Zhang.;Chen Suo.;Xingdong Chen.
来源: BMC Rheumatol. 2025年9卷1期1页
Elevated red blood cell distribution width (RDW) is associated with increased risk of rheumatoid arthritis (RA), but the potential interactions of RDW with genetic risk of incident RA remain unclear. This study aimed to investigate the associations between RDW, genetics, and the risk of developing RA.
547. Comparative effectiveness of disease-modifying antirheumatic drugs for patients with cardiac sarcoidosis.
作者: Lisbeth Brooks.;William Kivlin.;Divyanshu Mohananey.;Viktoriya Sabchyshyn.;Michael Putman.
来源: Rheumatology (Oxford). 2025年64卷6期3303-3308页
We aimed to evaluate the comparative efficacy of disease-modifying antirheumatic drugs (DMARDs) for patients with cardiac sarcoidosis.
548. Evaluation of hematological markers as prognostic tools in rheumatoid arthritis.
作者: Maryam Masoumi.;Maryam Bozorgi.;Zahra Nourmohammadi.;Mohammad Javad Mousavi.;Aref Shariati.;Jafar Karami.
来源: BMC Rheumatol. 2024年8卷1期75页
Reducing inflammation is central to the management of RA. However, commonly used markers such as CRP and ESR, along with the DAS-28 score, have shown limitations. Hematologic indices, such as platelet-lymphocyte ratio (PLR), lymphocyte-monocyte ratio (LMR), and neutrophil-lymphocyte ratio (NLR), show potential as reliable indicators of inflammation in RA. This study evaluates these markers across different RA activity levels to identify effective biomarkers for distinguishing active RA from remission.
549. Association of patient- and hospital-level predictors with patterns of initial treatment in patients with rheumatoid arthritis: findings from a national cohort study.
作者: Zijing Yang.;Edward Alveyn.;Mark Russell.;Katie Bechman.;Callum Coalwood.;Elizabeth Price.;Abhishek Abhishek.;Sam Norton.;James Galloway.
来源: Rheumatology (Oxford). 2025年64卷6期3379-3387页
To update the first-line conventional synthetic DMARDs (csDMARDs) prescribing pattern, describe change and variation across demographical and geographical factors in the RA population, and identify individual and hospital factors associated with it.
550. Predictors of rituximab efficacy in systemic sclerosis-associated interstitial lung disease: machine-learning analysis of the DESIRES trial.
作者: Ai Kuzumi.;Koji Oba.;Satoshi Ebata.;Kosuke Kashiwabara.;Keiko Ueda.;Yukari Uemura.;Takeyuki Watadani.;Takemichi Fukasawa.;Shunsuke Miura.;Asako Yoshizaki-Ogawa.;Hidenori Kage.;Shinichi Sato.;Ayumi Yoshizaki.
来源: Rheumatology (Oxford). 2025年64卷SI期SI114-SI121页
Rituximab is emerging as a promising therapeutic option for systemic sclerosis-associated interstitial lung disease (SSc-ILD). However, little is known about factors that predict the efficacy of rituximab in SSc-ILD.
551. The impact of an online, lifestyle intervention programme on the lives of patients with a rheumatic and musculoskeletal disease: a pilot study.
作者: Kim van Slingerland.;Laura J C Kranenburg.;Nathalie Wilmsen.;Emma Coles.;Radboud J E M Dolhain.;Pascal H P de Jong.
来源: Rheumatology (Oxford). 2025年64卷6期3309-3318页
To evaluate the short- and long-term effects of an online, interactive, multifactorial lifestyle intervention programme (Leef! Met Reuma) on health risk and all ICHOM-recommended patient-reported outcome measures (PROMs) in patients with an inflammatory arthritis (IA), osteoarthritis (OA) or fibromyalgia (FM).
552. Allogeneic haematopoietic stem-cell transplantation for children with refractory systemic juvenile idiopathic arthritis and associated lung disease: outcomes from an international, retrospective cohort study.
作者: Michael G Matt.;Daniel Drozdov.;Elisabeth Bendstrup.;Mia Glerup.;Ellen-Margrethe Hauge.;Tania Masmas.;Elvira Cannizzaro Schneider.;Ulrike B Zeilhofer.;Rolla F Abu-Arja.;Kyla D Driest.;Joseph H Oved.;Karen Onel.;Christen L Ebens.;Deepakbabu Chellapandian.;Shanmuganathan Chandrakasan.;Sampath Prahalad.;Johannes Roth.;Susan E Prockop.;Juliana Silva.;Andrew H Schapiro.;Christopher Towe.;Sharat Chandra.;Alexei Grom.;Grant S Schulert.;Rebecca A Marsh.
来源: Lancet Rheumatol. 2025年7卷4期e243-e251页
Systemic juvenile idiopathic arthritis-related lung disease (sJIA-LD) is a severe complication in patients with treatment-refractory systemic juvenile idiopathic arthritis (sJIA). The objective of this study was to evaluate the effect of allogeneic haematopoietic stem-cell transplantation (HSCT) in a cohort of children with sJIA-LD.
553. Utility of the GerdQ questionnaire in detecting gastroesophageal symptoms with RA patients.
作者: Yuji Nozaki.;Kazuya Kishimoto.;Daisuke Tomita.;Tetsu Itami.;Chisato Ashida.;Koji Kinoshita.;Itaru Matsumura.
来源: BMC Rheumatol. 2024年8卷1期73页
Rheumatoid arthritis (RA) affects multiple organ systems, including the esophagus. Moreover, one of the major side effects of methotrexate (MTX) is gastrointestinal disorders, which are said to affect medication adherence. We investigated the rate of MTX use, dosage, and the use of glucocorticoids (GCs) and oral non-steroidal anti-inflammatory drugs (NSAIDs) in relation to gastroesophageal (GE) symptoms, and whether they influence RA disease activity.
554. The association between composite dietary antioxidant index and rheumatoid arthritis: evidence from NHANES 2001-2020.
作者: Guangbin Ma.;Shulin Zhang.;Yiyan Luo.;Chengcheng Zhang.;Weina Xu.;Liyan Wang.
来源: BMC Rheumatol. 2024年8卷1期74页
This study aimed to investigate the relationship between the composite dietary antioxidant index (CDAI) and rheumatoid arthritis (RA) using data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2001 to 2020.
556. Total-body positron emission tomography: a tool for systemic, quantitative evaluation of the inflammatory burden of psoriatic arthritis.
作者: Siba P Raychaudhuri.;Yasser G Abdelhafez.;Dario F Mazza.;Smriti K Raychaudhuri.;Simon R Cherry.;Lorenzo Nardo.;Ramsey D Badawi.;Abhijit J Chaudhari.
来源: Rheumatology (Oxford). 2025年64卷6期3483-3491页
To test the hypothesis that recently-developed total body-positron emission tomography (TB-PET) imaging with integrated computed tomography (CT) will enable low-dose, quantitative, domain-specific evaluation of the total inflammatory burden of psoriatic arthritis (PsA) and associate with established outcome measures of the clinical domains of PsA.
557. Cardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data.
作者: Edoardo Cipolletta.;Georgina Nakafero.;Natalie McCormick.;Chio Yokose.;Anthony J Avery.;Mamas A Mamas.;Hyon K Choi.;Laila J Tata.;Abhishek Abhishek.
来源: Lancet Rheumatol. 2025年7卷3期e197-e207页
Initiating urate-lowering therapy can trigger gout flares. Gout flares have been associated with a temporally increased risk of cardiovascular events. Therefore, we aimed to estimate the risk of cardiovascular events in patients with gout initiating urate-lowering therapy with flare prophylaxis using colchicine (the drug recommended for gout flare prohphylaxis by many international societies) compared with no prophylaxis.
558. Association between serum urate levels and all-cause mortality, cardiovascular and renal outcomes among gout patients in Singapore.
作者: Moses Yidong Lim.;Weixiang Lian.;Hwee Pin Phua.;Htet Lin Htun.;Kok Ooi Kong.;Ling Li Foo.;Teo Min-Li Claire.;Wei-Yen Lim.
来源: BMC Rheumatol. 2024年8卷1期71页
We investigated the longitudinal association between Serum Urate (SU) level and Acute Myocardial Infarction (AMI), Stroke, End Stage Renal Failure (ESRF) and all-cause mortality.
559. The role of C-reactive protein and genetic predisposition in the risk of psoriasis: results from a national prospective cohort.
作者: Huarun Li.;Haobin Zhang.;Xiangyue Zhao.;Jinping Huang.;Junguo Zhang.;Zhaoyan Liu.;Ju Wen.;Si Qin.
来源: BMC Rheumatol. 2024年8卷1期72页
Psoriasis is an immune-mediated chronic inflammatory disease associated with multiple factors. To evaluate the extent to which C-reactive protein (CRP) and genetic predisposition affect the incidence of psoriasis.
560. Ultrasonography for the assessment of enthesitis in psoriatic arthritis: systematic review with meta-analysis.
作者: Noémie Bibas.;Caroline Pignon.;Clementina Lopez-Medina.;Frédérique Gandjbakhch.;Bruno Fautrel.;Laure Gossec.
来源: Rheumatology (Oxford). 2025年64卷5期2377-2384页
The specificity of US for enthesitis in PsA is unclear. The objective was to analyse the specificity of US enthesitis in Mode B and using power Doppler for the diagnosis of PsA through a systematic review with meta-analysis.
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