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461. Blocking the receptor for C5a in patients with rheumatoid arthritis does not reduce synovial inflammation.
作者: C E Vergunst.;D M Gerlag.;H Dinant.;L Schulz.;M Vinkenoog.;T J M Smeets.;M E Sanders.;K A Reedquist.;P P Tak.
来源: Rheumatology (Oxford). 2007年46卷12期1773-8页
All complement pathways lead to the formation of C5a, which is believed to contribute to the influx and activation of C5a-receptor (C5aR) bearing cells into the joints of patients with rheumatoid arthritis (RA). Studies in animal models of RA have suggested therapeutic potential of C5aR blockade. In this study, we examined the effects of the C5aR blockade on synovial inflammation in RA patients.
462. Arthritis patients show long-term benefits from 3 weeks intensive exercise training directly following hospital discharge.
作者: Y Bulthuis.;K W Drossaers-Bakker.;E Taal.;J Rasker.;J Oostveen.;P van't Pad Bosch.;F Oosterveld.;M van de Laar.
来源: Rheumatology (Oxford). 2007年46卷11期1712-7页
To examine the efficacy of short-term intensive exercise training (IET) directly following hospital discharge.
463. An economic evaluation of three physiotherapy treatments for non-specific neck disorders alongside a randomized trial.
作者: M Lewis.;M James.;E Stokes.;J Hill.;J Sim.;E Hay.;K Dziedzic.
来源: Rheumatology (Oxford). 2007年46卷11期1701-8页
Cost-effectiveness and cost-utility analyses were conducted to compare advice and exercise plus manual therapy (MT) and advice and exercise plus pulsed shortwave diathermy (PSWD) with advice and exercise alone (A&E) in the treatment of non-specific neck disorders by experienced physiotherapists.
464. Patient education in rheumatoid arthritis: the effectiveness of the ARC booklet and the mind map.
作者: D Walker.;A Adebajo.;P Heslop.;J Hill.;J Firth.;P Bishop.;P S Helliwell.
来源: Rheumatology (Oxford). 2007年46卷10期1593-6页
To determine the effectiveness of a pictorial 'mind map' together with the Arthritis Research Campaign (ARC) booklet for imparting knowledge to participants with rheumatoid arthritis (RA). Also, we wished to relate this to their reading ability.
465. Randomized trial of two physiotherapy interventions for primary care back and neck pain patients: cost effectiveness analysis.
作者: A Manca.;J C Dumville.;D J Torgerson.;J A Klaber Moffett.;M P Mooney.;D A Jackson.;S Eaton.
来源: Rheumatology (Oxford). 2007年46卷9期1495-501页
To assess the cost-effectiveness of a brief physiotherapy pain management approach using cognitive-behavioural principles (Solution-Finding Approach) when compared with a commonly used traditional method of physical therapy (McKenzie Approach).
466. Cost-effectiveness of Spa treatment for fibromyalgia: general health improvement is not for free.
作者: T R Zijlstra.;L M A Braakman-Jansen.;E Taal.;J J Rasker.;M A F J van de Laar.
来源: Rheumatology (Oxford). 2007年46卷9期1454-9页
To estimate the cost-effectiveness of an adjuvant treatment course of spa treatment compared with usual care only in patients with fibromyalgia syndrome (FM).
467. Short-term outcome of painful bone marrow oedema of the knee following oral treatment with iloprost or tramadol: results of an exploratory phase II study of 41 patients.
作者: M E Mayerhoefer.;J Kramer.;M J Breitenseher.;C Norden.;A Vakil-Adli.;S Hofmann.;R Meizer.;H Siedentop.;F Landsiedl.;N Aigner.
来源: Rheumatology (Oxford). 2007年46卷9期1460-5页
To compare the therapeutic effects of oral iloprost and tramadol on the outcome of bone marrow oedema (BME) of the knee by MR imaging and clinical assessment.
468. Radiographic progression in patients with ankylosing spondylitis after 4 yrs of treatment with the anti-TNF-alpha antibody infliximab.
作者: X Baraliakos.;J Listing.;J Brandt.;H Haibel.;M Rudwaleit.;J Sieper.;J Braun.
来源: Rheumatology (Oxford). 2007年46卷9期1450-3页
Anti-tumour necrosis factor therapy with infliximab has been shown to improve signs and symptoms of patients with active ankylosing spondylitis (AS). The objective of this article was to study the effect of infliximab on structural changes in AS over 4 yrs.
469. Severe knee osteoarthritis: a randomized controlled trial of acupuncture, physiotherapy (supervised exercise) and standard management for patients awaiting knee replacement.
To evaluate the effects of standardized western acupuncture and physiotherapy on pain and functional ability in patients with severe osteoarthritic knee pain awaiting knee arthroplasty.
470. Do baseline characteristics predict response to treatment for low back pain? Secondary analysis of the UK BEAM dataset [ISRCTN32683578].
To identify characteristics of randomized controlled trial participants which predict greater benefits from physical treatments for low back pain. If successful, this would allow more appropriate selection of patients for different treatments.
471. Elevated relapse rate under oral methotrexate versus leflunomide for maintenance of remission in Wegener's granulomatosis.
作者: C Metzler.;N Miehle.;K Manger.;C Iking-Konert.;K de Groot.;B Hellmich.;W L Gross.;E Reinhold-Keller.; .
来源: Rheumatology (Oxford). 2007年46卷7期1087-91页
Results from open-label trials suggest that methotrexate (MTX) and leflunomide (LEF) are effective for maintenance of remission in Wegener's granulomatosis (WG), but data from randomized controlled clinical trails are not yet available.
472. Lumiracoxib 400 mg once daily is comparable to indomethacin 50 mg three times daily for the treatment of acute flares of gout.
作者: R E Willburger.;E Mysler.;J Derbot.;T Jung.;H Thurston.;A Kreiss.;S Litschig.;G Krammer.;G A Tate.
来源: Rheumatology (Oxford). 2007年46卷7期1126-32页
To demonstrate non-inferiority of lumiracoxib 400 mg once daily (o.d.) compared with indomethacin 50 mg three times daily (t.i.d.) in the treatment of acute gout, and to compare the safety and tolerability of these treatments.
473. A placebo-controlled, randomized, double-blinded study evaluating the safety of etanercept in patients with rheumatoid arthritis and concomitant comorbid diseases.
作者: Michael H Weisman.;Harold E Paulus.;Francis X Burch.;Alan J Kivitz.;Joshua Fierer.;Meleana Dunn.;David R Kerr.;Wayne Tsuji.;Scott W Baumgartner.
来源: Rheumatology (Oxford). 2007年46卷7期1122-5页
To evaluate the safety of etanercept in patients with rheumatoid arthritis (RA) and concomitant comorbidities.
474. Improvement in patient-reported outcomes for patients with ankylosing spondylitis treated with etanercept 50 mg once-weekly and 25 mg twice-weekly.
The objective of this study was to assess the humanistic impact of ankylosing spondylitis (AS), and compare the effect of etanercept 50 mg once-weekly (QW), etanercept 25 mg twice-weekly (BIW) and placebo on patient-reported outcomes (PROs).
475. Compared clinical efficacy and bone metabolic effects of low-dose deflazacort and methyl prednisolone in male inflammatory arthropathies: a 12-month open randomized pilot study.
作者: G Saviola.;L Abdi Ali.;S Shams Eddin.;A Coppini.;F Cavalieri.;L Campostrini.;S Sacco.;M Bucci.;G Cirino.;M Rossini.
来源: Rheumatology (Oxford). 2007年46卷6期994-8页
To evaluate: (i) a correct equivalence ratio of clinical efficacy between low-dose deflazacort (DFZ) and methyl prednisolone (MP); and (ii) bone metabolic effects of low-dose DFZ and MP in the treatment of male RA and PsA.
476. The overall status in rheumatoid arthritis (OSRA) measure--further evidence to support its use in clinical practice.
作者: M J Harrison.;A Hassell.;P T Dawes.;D L Scott.;S M Knight.;M J Davis.;D Mulherin.;D P M Symmons.
来源: Rheumatology (Oxford). 2007年46卷5期849-55页
The overall status in rheumatoid arthritis (OSRA) instrument is a simple summary of health status, including disease activity (OSRA-A) and damage (OSRA-D) scores. Despite evidence of the validity of the OSRA, uptake has been low. This study aimed to assess the responsiveness and re-examine the validity of the OSRA using the measures from the British Rheumatoid Outcome Study Group (BROSG) randomized controlled trial of aggressive vs symptomatic treatment of rheumatoid arthritis (RA) patients.
477. A prospective double blind placebo-controlled randomized trial of ultrasound in the physiotherapy treatment of shoulder pain.
作者: R Ainsworth.;K Dziedzic.;L Hiller.;J Daniels.;A Bruton.;J Broadfield.
来源: Rheumatology (Oxford). 2007年46卷5期815-20页
To compare the effectiveness of manual therapy and ultrasound (US) with manual therapy and placebo ultrasound (placebo US) in the treatment of new episodes of unilateral shoulder pain referred for physiotherapy.
478. Sustained benefit in rheumatoid arthritis following one course of rituximab: improvements in physical function over 2 years.
作者: V Strand.;A Balbir-Gurman.;K Pavelka.;P Emery.;N Li.;M Yin.;P B Lehane.;S Agarwal.
来源: Rheumatology (Oxford). 2006年45卷12期1505-13页
To evaluate the long-term impact on physical function of a single course of rituximab in rheumatoid factor, seropositive patients with active rheumatoid arthritis (RA) despite ongoing methotrexate treatment.
479. Randomized trial of two physiotherapy interventions for primary care neck and back pain patients: 'McKenzie' vs brief physiotherapy pain management.
作者: J Klaber Moffett.;D A Jackson.;E D Gardiner.;D J Torgerson.;S Coulton.;S Eaton.;M P Mooney.;C Pickering.;A J Green.;L G Walker.;S May.;S Young.
来源: Rheumatology (Oxford). 2006年45卷12期1514-21页
Interventions that take psychosocial factors into account are recommended for patients with persistent back or neck pain. We compared the effectiveness of a brief physiotherapy pain management approach using cognitive-behavioural principles (Solution-Finding Approach-SFA) with a commonly used method of physical therapy (McKenzie Approach-McK).
480. Engagement and satisfaction with an Internet-based physical activity intervention in patients with rheumatoid arthritis.
作者: M H van den Berg.;H K Ronday.;A J Peeters.;E M Voogt-van der Harst.;M Munneke.;F C Breedveld.;T P M Vliet Vlieland.
来源: Rheumatology (Oxford). 2007年46卷3期545-52页
To assess the engagement in and satisfaction with an Internet-mediated physical activity intervention with individual supervision in patients with rheumatoid arthritis (RA).
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