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共有 3919 条符合本次的查询结果， 用时 2.1039679 秒

421. Sequencing of Circulating Cell-free DNA during Pregnancy.

作者: Diana W Bianchi.;Rossa W K Chiu.
来源: N Engl J Med. 2018年379卷5期464-473页
Sequence analysis of cell-free DNA (cfDNA) fragments that circulate in the blood of pregnant women, along with the translation of this method into screening for fetal chromosome abnormalities, is a success story of modern genomic medicine. In less than a decade, prenatal cfDNA testing has gone from small, proof-of-principle studies to a global transformation of prenatal care. As of late 2017, a total of 4 million to 6 million pregnant women had had DNA from their plasma analyzed to screen for fetal aneuploidy. The exponential growth of the test has been a function of the role of the biotechnology industry in its development and marketing. Here we review what has been learned from the wide-scale implementation of this testing, how it has changed prenatal clinical care, and what ethical concerns have arisen, and we speculate about what lies ahead.

422. Update on Keratinocyte Carcinomas.

作者: Kishwer S Nehal.;Christopher K Bichakjian.
来源: N Engl J Med. 2018年379卷4期363-374页

423. Psychotic Disorders.

作者: Jeffrey A Lieberman.;Michael B First.
来源: N Engl J Med. 2018年379卷3期270-280页

424. Chronic Limb-Threatening Ischemia.

作者: Alik Farber.
来源: N Engl J Med. 2018年379卷2期171-180页

425. Chimeric Antigen Receptor Therapy.

作者: Carl H June.;Michel Sadelain.
来源: N Engl J Med. 2018年379卷1期64-73页

426. Prophylaxis against Upper Gastrointestinal Bleeding in Hospitalized Patients.

作者: Deborah Cook.;Gordon Guyatt.
来源: N Engl J Med. 2018年378卷26期2506-2516页

427. Subclinical Hyperthyroidism.

作者: Bernadette Biondi.;David S Cooper.
来源: N Engl J Med. 2018年378卷25期2411-2419页

428. Breast Cancer in Men.

作者: Sharon H Giordano.
来源: N Engl J Med. 2018年378卷24期2311-2320页

429. Dry Eye.

作者: Janine A Clayton.
来源: N Engl J Med. 2018年378卷23期2212-2223页

430. Multiplicity Considerations in Clinical Trials.

作者: Alex Dmitrienko.;Ralph B D'Agostino.
来源: N Engl J Med. 2018年378卷22期2115-2122页

431. Diagnosis and Management of the Antiphospholipid Syndrome.

作者: David Garcia.;Doruk Erkan.
来源: N Engl J Med. 2018年378卷21期2010-2021页

432. Idiopathic Pulmonary Fibrosis.

作者: David J Lederer.;Fernando J Martinez.
来源: N Engl J Med. 2018年378卷19期1811-1823页

433. Essential Tremor.

作者: Dietrich Haubenberger.;Mark Hallett.
来源: N Engl J Med. 2018年378卷19期1802-1810页

434. Calciphylaxis.

作者: Sagar U Nigwekar.;Ravi Thadhani.;Vincent M Brandenburg.
来源: N Engl J Med. 2018年378卷18期1704-1714页

435. Toxidrome Recognition in Chemical-Weapons Attacks.

作者: Gregory R Ciottone.
来源: N Engl J Med. 2018年378卷17期1611-1620页

436. Placenta Accreta Spectrum.

作者: Robert M Silver.;D Ware Branch.
来源: N Engl J Med. 2018年378卷16期1529-1536页

437. Diagnostic Use of Base Excess in Acid-Base Disorders.

作者: Kenrick Berend.
来源: N Engl J Med. 2018年378卷15期1419-1428页

438. The Key Role of Epigenetics in Human Disease Prevention and Mitigation.

作者: Andrew P Feinberg.
来源: N Engl J Med. 2018年378卷14期1323-1334页

439. Tinnitus.

作者: Carol A Bauer.
来源: N Engl J Med. 2018年378卷13期1224-1231页

440. Autoimmune Polyendocrine Syndromes.

作者: Eystein S Husebye.;Mark S Anderson.;Olle Kämpe.
来源: N Engl J Med. 2018年378卷12期1132-1141页
共有 3919 条符合本次的查询结果， 用时 2.1039679 秒