当前位置: 首页 >> 检索结果
4041. Oral L-arginine in patients with coronary artery disease on medical management.
作者: A Blum.;L Hathaway.;R Mincemoyer.;W H Schenke.;M Kirby.;G Csako.;M A Waclawiw.;J A Panza.;R O Cannon.
来源: Circulation. 2000年101卷18期2160-4页
Vascular nitric oxide (NO) bioavailability is reduced in patients with coronary artery disease (CAD). We investigated whether oral L-arginine, the substrate for NO synthesis, improves homeostatic functions of the vascular endothelium in patients maintained on appropriate medical therapy and thus might be useful as adjunctive therapy.
4042. Beneficial effects of intracoronary adenosine as an adjunct to primary angioplasty in acute myocardial infarction.
The benefits of vessel recanalization in acute myocardial infarction (AMI) are limited by reperfusion damage. In animal models, adenosine limits reperfusion injury, reducing infarct size and improving ventricular function. The aim of this study was to evaluate the safety and feasibility of adenosine adjunct to primary PTCA in AMI.
4043. ST-Segment recovery adds to the assessment of TIMI 2 and 3 flow in predicting infarct wall motion after thrombolytic therapy.
作者: J Andrews.;I T Straznicky.;J K French.;C L Green.;A C Maas.;M Lund.;M W Krucoff.;H D White.
来源: Circulation. 2000年101卷18期2138-43页
Early resolution of ST-segment elevation (ST-segment recovery) is associated with an improved outcome after infarction. Whether this relation is present in patients with Thrombolysis In Myocardial Infarction (TIMI) grade 2 or 3 flow (ie, patent) infarct-related arteries is not known.
4044. Electron-beam computed tomography in the assessment of coronary artery disease after heart transplantation.
作者: F D Knollmann.;W Bocksch.;S Spiegelsberger.;R Hetzer.;R Felix.;M Hummel.
来源: Circulation. 2000年101卷17期2078-82页
Our aim was to compare the electron-beam CT (EBCT) features of coronary arteries in heart transplant recipients with those of biplane coronary angiography and intracoronary ultrasound (ICUS).
4045. Improvement in exercise capacity with nitric oxide inhalation in patients with precapillary pulmonary hypertension.
作者: T Hasuda.;T Satoh.;A Shimouchi.;F Sakamaki.;S Kyotani.;T Matsumoto.;Y Goto.;N Nakanishi.
来源: Circulation. 2000年101卷17期2066-70页
Patients with precapillary pulmonary hypertension (PH) exhibit a poor exercise capacity due to an impaired vasodilatory response of their pulmonary arteries. By causing the pulmonary artery to dilate, inhaled nitric oxide (NO) may allow an increase in exercise capacity in patients with PH.
4046. Nitric oxide spares myocardial oxygen consumption through attenuation of contractile response to beta-adrenergic stimulation in patients with idiopathic dilated cardiomyopathy.
作者: T Shinke.;H Takaoka.;M Takeuchi.;K Hata.;H Kawai.;H Okubo.;Y Kijima.;T Murata.;M Yokoyama.
来源: Circulation. 2000年101卷16期1925-30页
The results of recent studies suggest that NO synthase may increase in the failing myocardium and that NO modulates the myocardial contractile response to beta-adrenergic stimulation. However, there are few data regarding the physiological role of NO in patients with heart failure. The aim of the present study was to address the role of NO in left ventricular (LV) contractile response to beta-adrenergic stimulation and corresponding oxygen expenditure in human heart failure.
4047. Intracoronary beta-radiation therapy inhibits recurrence of in-stent restenosis.
作者: R Waksman.;B Bhargava.;L White.;R C Chan.;R Mehran.;A J Lansky.;G S Mintz.;L F Satler.;A D Pichard.;M B Leon.;K K Kent.
来源: Circulation. 2000年101卷16期1895-8页
Intracoronary gamma-radiation therapy reduces recurrent in-stent restenosis (ISR). This study, BETA WRIST (Washington Radiation for In-Stent restenosis Trial) was designed to examine the efficacy and safety of the beta-emitter 90-yttrium for the prevention of recurrent ISR.
4048. Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus.
作者: M Evans.;R A Anderson.;J Graham.;G R Ellis.;K Morris.;S Davies.;S K Jackson.;M J Lewis.;M P Frenneaux.;A Rees.
来源: Circulation. 2000年101卷15期1773-9页
Exaggerated postprandial lipemia (PPL) is a factor in atherogenesis, involving endothelial dysfunction and enhanced oxidative stress. We examined the effect of ciprofibrate therapy on these parameters in type 2 diabetes mellitus.
4049. Coronary artery imaging in grown up congenital heart disease: complementary role of magnetic resonance and x-ray coronary angiography.
作者: A M Taylor.;S A Thorne.;M B Rubens.;P Jhooti.;J Keegan.;P D Gatehouse.;F Wiesmann.;F Grothues.;J Somerville.;D J Pennell.
来源: Circulation. 2000年101卷14期1670-8页
There is a high incidence of anomalous coronary arteries in subjects with congenital heart disease. These abnormalities can be responsible for myocardial ischemia and sudden death or be damaged during surgical intervention. It can be difficult to define the proximal course of anomalous coronary arteries with the use of conventional x-ray coronary angiography. Magnetic resonance coronary angiography (MRCA) has been shown to be useful in the assessment of the 3-dimensional relationship between the coronary arteries and the great vessels in subjects with normal cardiac morphology but has not been used in patients with congenital heart disease.
4050. Identification of patients most likely to benefit from implantable cardioverter-defibrillator therapy: the Canadian Implantable Defibrillator Study.
作者: R Sheldon.;S Connolly.;A Krahn.;R Roberts.;M Gent.;M Gardner.
来源: Circulation. 2000年101卷14期1660-4页
Patients with resuscitated ventricular tachyarrhythmias (ventricular tachycardia/ventricular fibrillation) benefit from implantable cardioverter-defibrillators (ICDs) compared with medical therapy. We hypothesized that the patients who benefit most from an ICD are those at greatest risk of death.
4051. Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan.
Structural and functional alterations of the vasculature may contribute to complications of hypertension. Because angiotensin II may be pivotal in some of these vascular abnormalities, we tested the hypothesis that the angiotensin type 1 (AT(1)) receptor antagonist losartan, in contrast to the beta-blocker atenolol, would correct resistance artery abnormalities in patients with essential hypertension.
4052. Carvedilol for prevention of restenosis after directional coronary atherectomy : final results of the European carvedilol atherectomy restenosis (EUROCARE) trial.
作者: P W Serruys.;D P Foley.;B Höfling.;J Puel.;H D Glogar.;R Seabra-Gomes.;J Goicolea.;P Coste.;W Rutsch.;H Katus.;H Bonnier.;W Wijns.;A Betriu.;U Hauf-Zachariou.;E M van Swijndregt.;R Melkert.;R Simon.
来源: Circulation. 2000年101卷13期1512-8页
In addition to its known properties as a competitive, nonselective beta and alpha-1 receptor blocker, carvedilol directly inhibits vascular myocyte migration and proliferation and exerts antioxidant effects that are considerably greater than those of vitamin E or probucol. This provides the basis for an evaluation of carvedilol for the prevention of coronary restenosis.
4054. Pharmacokinetic evaluation of triiodothyronine supplementation in children after modified Fontan procedure.
作者: R D Mainwaring.;E Capparelli.;K Schell.;M Acosta.;J C Nelson.
来源: Circulation. 2000年101卷12期1423-9页
Triiodothyronine (T(3)) supplementation may be a useful adjunct in the management of patients after cardiopulmonary bypass. Limited data are available regarding the use and pharmacokinetics of T(3) in children. The present study was performed to evaluate T(3) pharmacokinetics in a cohort of children undergoing the modified Fontan procedure.
4055. L-NMMA (a nitric oxide synthase inhibitor) is effective in the treatment of cardiogenic shock.
作者: G Cotter.;E Kaluski.;A Blatt.;O Milovanov.;Y Moshkovitz.;R Zaidenstein.;A Salah.;D Alon.;Y Michovitz.;M Metzger.;Z Vered.;A Golik.
来源: Circulation. 2000年101卷12期1358-61页
The objective was to assess the safety and efficacy of L-NMMA in the treatment of cardiogenic shock.
4056. Canadian implantable defibrillator study (CIDS) : a randomized trial of the implantable cardioverter defibrillator against amiodarone.
作者: S J Connolly.;M Gent.;R S Roberts.;P Dorian.;D Roy.;R S Sheldon.;L B Mitchell.;M S Green.;G J Klein.;B O'Brien.
来源: Circulation. 2000年101卷11期1297-302页
Patients surviving ventricular fibrillation (VF) or sustained ventricular tachycardia (VT) are at a high risk of death due to a recurrence of arrhythmia. The implantable cardioverter defibrillator (ICD) terminates VT or VF, but it is not known whether this device prolongs life in these patients compared with medical therapy with amiodarone.
4057. Transthoracic cardioversion of atrial fibrillation: comparison of rectilinear biphasic versus damped sine wave monophasic shocks.
作者: S Mittal.;S Ayati.;K M Stein.;D Schwartzman.;D Cavlovich.;P J Tchou.;S M Markowitz.;D J Slotwiner.;M A Scheiner.;B B Lerman.
来源: Circulation. 2000年101卷11期1282-7页
Clinical studies have shown that biphasic shocks are more effective than monophasic shocks for ventricular defibrillation. The purpose of this study was to compare the efficacy of a rectilinear biphasic waveform with a standard damped sine wave monophasic waveform for the transthoracic cardioversion of atrial fibrillation.
4058. Enoximone echocardiography for predicting recovery of left ventricular dysfunction after revascularization : a novel test for detecting myocardial viability.
作者: C Lu.;M Carlino.;G Fragasso.;F Maisano.;A Margonato.;A Cappelletti.;S L Chierchia.
来源: Circulation. 2000年101卷11期1255-60页
The possibility that enoximone, a nonglycoside, noncatechol, positive inotropic agent, in combination with 2-dimensional echocardiography may predict recovery of myocardial dysfunction after revascularization has not been yet evaluated.
4059. Effects of abciximab, ticlopidine, and combined Abciximab/Ticlopidine therapy on platelet and leukocyte function in patients undergoing coronary angioplasty.
作者: B J Fredrickson.;N A Turner.;N S Kleiman.;N Graziadei.;K Maresh.;M A Mascelli.;M B Effron.;L V McIntire.
来源: Circulation. 2000年101卷10期1122-9页
Abciximab and ticlopidine reduce adverse cardiovascular events after percutaneous transluminal coronary angioplasty (PTCA). The goal of the current study was to determine if combined abciximab/ticlopidine therapy inhibits arterial thrombosis more effectively than either treatment alone. The effect of each therapy on platelet-leukocyte interactions was also investigated.
4060. Low molecular weight heparin after mechanical heart valve replacement.
作者: G Montalescot.;V Polle.;J P Collet.;P Leprince.;A Bellanger.;I Gandjbakhch.;D Thomas.
来源: Circulation. 2000年101卷10期1083-6页
Patients with mechanical heart valves require life-long anticoagulation. We report here the first large and comparative series of consecutive patients anticoagulated with low molecular weight heparin (LMWH) after mechanical heart valve replacement.
|