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381. Clinical Features of Myocardial Infarction in Women With a History of Preeclampsia: A Population-Based Cohort Study.
作者: Neja Mudrovcic.;Elin Tegnesjö.;Rasmus Walter Green.;Maria Jonsson.;Christina Christersson.;Lina Bergman.;Karl Bergman.;Anna-Karin Wikström.;Susanne Hesselman.
来源: Circ Cardiovasc Qual Outcomes. 2025年18卷5期e011442页
Preeclampsia is associated with an increased lifetime risk of myocardial infarction. This study explored whether there is a difference in the clinical features and severity of myocardial infarction in women with previous preeclampsia compared with women with no history of preeclampsia.
382. Alcohol Exposure Among Patients With Dilated Cardiomyopathy and Their First-Degree Relatives: The DCM Precision Medicine Study.
作者: Javier Jimenez.;Hanyu Ni.;Stuart D Katz.;Garrie J Haas.;Jinwen Cao.;Muni Rubens.;Sandra Chaparro.;Anshul Saxena.;Mark Hofmeyer.;Evan Kransdorf.;Gregory A Ewald.;Alanna A Morris.;Anjali Owens.;Brian Lowes.;Douglas Stoller.;W H Wilson Tang.;Palak Shah.;Jane E Wilcox.;Frank Smart.;Jessica Wang.;Stephen S Gottlieb.;Daniel P Judge.;Jonathan O Mead.;Natalie Hurst.;Patricia K Parker.;Gordon S Huggins.;Elizabeth Jordan.;Daniel D Kinnamon.;Ray E Hershberger.; .
来源: Circ Genom Precis Med. 2025年18卷2期e004946页
Whether prolonged and excessive alcohol consumption contributes to dilated cardiomyopathy (DCM) remains uncertain. This study aimed to describe the prevalence of alcohol use in patients with DCM and their first-degree relatives (FDRs) and determine if cumulative alcohol exposure associates with DCM/partial DCM or modifies the association of DCM with DCM-relevant rare variants.
383. Evaluating Patient and Provider Experiences of Enrolling in a Remote Cardiovascular Health Program: A Qualitative Interview Study.
作者: Wesley Alexandra Spacht.;Simin Gharib Lee.;Matthew Varugheese.;Samantha Subramaniam.;Marian McPartlin.;Michela R Tucci.;Benjamin M Scirica.
来源: Circ Cardiovasc Qual Outcomes. 2025年18卷4期e010394页
Remote health management programs utilizing evidence-based algorithm-driven virtual care solutions for chronic disease management offer a novel approach to addressing implementation gaps for conditions such as hypertension. However, little is known about how to optimize patient enrollment.
384. Artificial Intelligence-Enhanced Analysis of Echocardiography-Based Radiomic Features for Myocardial Hypertrophy Detection and Etiology Differentiation.
作者: Inki Moon.;Jina Lee.;Seung-Ah Lee.;Dawun Jeong.;Jaeik Jeon.;Yeonggul Jang.;Sihyeon Jeong.;Jiyeon Kim.;Hong-Mi Choi.;In-Chang Hwang.;Youngtaek Hong.;Goo-Yeong Cho.;Yeonyee E Yoon.;Hyuk-Jae Chang.
来源: Circ Cardiovasc Imaging. 2025年18卷5期e017436页
While echocardiography is pivotal for detecting left ventricular hypertrophy (LVH), it struggles with etiology differentiation. To enhance LVH assessment, we aimed to develop an artificial intelligence algorithm using echocardiography-based radiomics. This algorithm is designed to detect LVH and differentiate its common etiologies, such as hypertrophic cardiomyopathy (HCM), cardiac amyloidosis (CA), and hypertensive heart disease (HHD), based on echocardiographic images.
386. Novel Protein-Based Biomarkers of Out-of-hospital Sudden Cardiac Death After Myocardial Infarction.
作者: Maomao Zhang.;Zhonghua Tong.;Naixin Wang.;Kaiyang Lin.;Yafei Zhang.;Dongni Wang.;Xiaoqi Wang.;Penghe Wang.;Qiannan Yang.;Yingjin Kong.;Mengdi Wang.;Jingxuan Cui.;Zhuozhong Wang.;Muhua Cao.;Lulu Li.;Ying Liu.;Zhaoying Li.;Shaohong Fang.;Fan Zhang.;Zhenwei Pan.;Jinwei Tian.;Bo Yu.
来源: Circ Arrhythm Electrophysiol. 2025年18卷4期e013217页
Early identification of out-of-hospital high-risk sudden cardiac death (SCD) after acute myocardial infarction is crucial for timely therapeutic interventions. However, left ventricular ejection fraction as a standalone clinical stratification tool has major limitations, necessitating improved risk stratification strategies.
387. One-Year Safety and Performance of a Dual-Chamber Leadless Pacemaker.
作者: Reinoud E Knops.;James E Ip.;Rahul Doshi.;Derek V Exner.;Pascal Defaye.;Robert Canby.;Maria Grazia Bongiorni.;Morio Shoda.;Gerhard Hindricks.;Petr Neužil.;Mayer Rashtian.;Karel T N Breeman.;Jordan R Nevo.;Leonard Ganz.;Chris Hubbard.;Anu Bulusu.;Vivek Y Reddy.
来源: Circ Arrhythm Electrophysiol. 2025年18卷4期e013619页
A dual-chamber leadless pacemaker can provide bradycardia therapy to most patients with pacemaker indications without the complications associated with a lead or pulse generator. We sought to confirm whether previously reported 3-month safety and performance outcomes were sustained through 12 months by determining whether 12-month complication-free and performance success rates exceeded their prespecified performance goals.
389. Transcarotid Versus Surgical Aortic Valve Replacement for the Treatment of Severe Aortic Stenosis.
作者: Juan Hernando Del Portillo.;Pedro Cepas-Guillén.;Dimitri Kalavrouziotis.;Eric Dumont.;Jean Porterie.;Jean-Michel Paradis.;Anthony Poulin.;Frederic Beaupré.;Marisa Avvedimento.;Silvia Mas-Peiro.;Siddhartha Mengi.;Siamak Mohammadi.;Josep Rodés-Cabau.
来源: Circ Cardiovasc Interv. 2025年18卷4期e014928页
Current guidelines recommend surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and unfavorable iliofemoral access. Transcarotid transcatheter aortic valve replacement (TC-TAVR) has emerged as an alternative access in suboptimal transfemoral candidates, but no data exist comparing TC-TAVR and SAVR. The main objective of this study was to compare the clinical outcomes in a propensity-matched population of TC-TAVR and SAVR patients with severe aortic stenosis.
390. Reconsidering Pre-Procedural Fasting for Elective Percutaneous Cardiac Procedures.
作者: Sammudeen Ibrahim.;Shreyas Singireddy.;Chidubem Ezenna.;Laura M Romero Acero.;Armin Nouri.;Zafer Akman.;Golsa Babapour.;Jennifer Frampton.;Andrew M Goldsweig.;Abdulla A Damluji.;Michael G Nanna.
来源: Circ Cardiovasc Interv. 2025年18卷4期e015089页 391. Predictive Value of Platelet FcγRIIa in Patients Treated With PCI Compared With Medical Therapy Alone After Myocardial Infarction.
作者: David J Schneider.;Sean R McMahon.;Dominick J Angiolillo.;Alexander C Fanaroff.;Homam Ibrahim.;Patrick K Hohl.;Brett L Wanamaker.;Mark B Effron.;Peter M DiBattiste.; .
来源: Circ Cardiovasc Interv. 2025年18卷4期e014939页
In patients with myocardial infarction (MI), quantifying platelet FcɣRIIa (pFCG) stratifies the risk of subsequent MI, stroke, and death. This report is a subgroup analysis of outcomes in patients treated with percutaneous coronary intervention (PCI) or medical management alone in an 800-patient, 25-center trial.
393. Blood Transfusion in Patients With Acute Myocardial Infarction, Anemia, and Heart Failure: Lessons From MINT.
作者: Andrew M Goldsweig.;William J Kostis.;Brandon M Herbert.;Claire Bouleti.;Brian J Potter.;Jordan B Strom.;Jocelyne Benatar.;Thao Huynh.;Srikanth Vallurupalli.;Estêvão Lanna Figueiredo.;J Dawn Abbott.;Howard A Cooper.;Andrew P DeFilippis.;Dean A Fergusson.;Shaun G Goodman.;Paul C Hébert.;Renato D Lopes.;Sunil V Rao.;Tabassome Simon.;Jeffrey L Carson.;Maria Mori Brooks.;John H Alexander.; .
来源: Circ Heart Fail. 2025年18卷4期e012495页
Blood transfusion may precipitate adverse outcomes, including heart failure (HF), among patients with acute myocardial infarction (MI). This study characterizes the effects of a restrictive or liberal transfusion strategy on outcomes in patients with MI and anemia with and without baseline HF.
395. XBP1s-EDEM2 Prevents the Onset and Development of HFpEF by Ameliorating Cardiac Lipotoxicity.
作者: Oveena Fonseka.;Rida Raja.;Claire Ross.;Sanskruti R Gare.;Jiayan Zhang.;Susanne S Hille.;Katharine King.;Andrea Ruiz-Velasco.;Namrita Kaur.;Xinyi Chen.;Jessica M Miller.;Riham R E Abouleisa.;Qinghui Ou.;Zhiyong Zou.;Xiangjun Zhao.;Cristian Sotomayor-Flores.;Derk Frank.;Eileithyia Swanton.;Martin R Pool.;Sara Missaglia.;Daniela Tavian.;Gabriele G Schiattarella.;Tao Wang.;Luigi Venetucci.;Christian Pinali.;Martin K Rutter.;Bernard D Keavney.;Elizabeth J Cartwright.;Tamer M A Mohamed.;Oliver J Müller.;Wei Liu.
来源: Circulation. 2025年151卷22期1583-1605页
Morbidity and mortality of heart failure with preserved ejection fraction (HFpEF) is increased in metabolic disorders. However, options for preventing and treating these prevalent outcomes are limited. Intramyocardial lipotoxicity contributes to cardiac dysfunction. Here, we investigate the mechanisms underlying EDEM2 (endoplasmic reticulum degradation-enhancing alpha-mannosidase-like protein 2) regulation of cardiac lipid homeostasis and assess strategies that inhibit the incidence and progression of HFpEF.
396. Valve-in-Valve TAVR in Patients With Failed Trifecta Bioprosthetic Aortic Valves.
作者: Mohammad Zmaili.;Nikolaos Spilias.;Shivabalan Kathavarayan Ramu.;Tikal Kansara.;Akhilesh Khuttan.;Maryam Muhammad Ali Majeed-Saidan.;Besir Besir.;Rohan Prasad.;Judah Rajendran.;Feras Alkhalaileh.;Ahmad Gharaibeh.;Agam Bansal.;Abdelrahman Abushouk.;Serge Harb.;Rishi Puri.;Grant Reed.;James Yun.;Amar Krishnaswamy.;Samir Kapadia.
来源: Circ Cardiovasc Interv. 2025年18卷5期e014532页 399. Combined RNA Splicing and Patch-Clamp Analysis Reveal Pathogenicity of Splice-Altering Variants in KCNH2-Related LQTS.
作者: Susan Clasper.;Gunjan Trivedi.;Kate L Thomson.;Claire L S Turner.;Smrithi Devaiah.;Catherine L Mercer.;Amnah Y Bdeir.;Jumana Y Al-Aama.;Khalid Dagriri.;Alex R Hobson.;Shankar N Sadagopan.;Julian Ormerod.;Eszter Szepesvary.;Justin Phan.;Diane Fatkin.;Jamie I Vandenberg.;Zahurul A Bhuiyan.;Chai-Ann Ng.
来源: Circ Genom Precis Med. 2025年18卷2期e004966页 |