当前位置: 首页 >> 检索结果
22. A Mammarenavirus Close to Lassa Virus in a Patient with Meningoencephalitis.
作者: Sylvain Baize.;Delphine Pannetier.;Christophe Rodriguez.;Laurence Josset.;Franck de Laval.;Bernadette Gergonne.;Jean-Baptiste Mardon.;Caroline Picard.;Alexandra Journeaux.;Damien Thomas.;Elodie Moissonnier.;Céline Ragot.;Thibault Martinez.;Estelle Lara.;Anne-Laure Favier.;Olivier Ferraris.;Magali Billhot.;Mathieu Cabon.; .
来源: N Engl J Med. 2025年393卷19期1960-1962页 23. Antithrombotic Therapy after Successful Catheter Ablation for Atrial Fibrillation.
作者: Atul Verma.;David H Birnie.;Chenyang Jiang.;Hein Heidbüchel.;Gerhard Hindricks.;Paulus Kirchhof.;Jeff S Healey.;Yunhe Wang.;Nikolaos Dagres.;Marc W Deyell.;Prashanthan Sanders.;Rajeev K Pathak.;Pieter Koopman.;Dieter Nuyens.;Paul Novak.;Guy Amit.;Charles Dussault.;Bhavanesh Makanjee.;F Russell Quinn.;Umjeet Jolly.;Leon Iden.;Malte Kuniss.;Mukul Sharma.;Andrew Ha.;Vidal Essebag.;Jean Champagne.;Michael D Hill.;Eric E Smith.;George A Wells.; .
来源: N Engl J Med. 2026年394卷4期323-332页
Whether successful catheter ablation for atrial fibrillation eliminates the need for long-term oral anticoagulant therapy is unknown.
24. Safety and Immunogenicity of an rVSV Lassa Fever Vaccine Candidate.
作者: Elissa Malkin.;Marija Zaric.;Mark Kieh.;Lindsey R Baden.;David Fitz-Patrick.;Arianna Marini.;Heejin Yun.;Peter Hayes.;Rachel Bromell.;Morolayo Ayorinde.;Natalia Fernandez.;Ruhani Varma.;Faith Sigei.;Matthew Ward.;Hema Pindolia.;Shayna Sewell.;Fahimah Amini.;Julie Blie.;Barthalomew Wilson.;Patrick Faley.;John McCullough.;Franklin Tokpah.;Cecelia Wisseh.;Elvis Towalid.;Swapnil Hadawale.;Eddy Sayeed.;Devin Hunt.;Nahid Keshavarzi.;Burc Barin.;Irina Maljkovic Berry.;Christopher L Parks.;Shobhna Gopal Truter.;Kathleen Walker.;Johan Vekemans.;Jennifer Lehrman.;Michelle Engelbrecht.;Mariette Malherbe.;Dagna Laufer.;Vincent Philiponis.;Elizabeth Higgs.;Gaudensia Mutua.;Patricia E Fast.;Swati B Gupta.; .
来源: N Engl J Med. 2025年393卷18期1807-1818页
No vaccine is currently available for Lassa fever, a viral hemorrhagic disease that is estimated to cause thousands of deaths each year in western Africa. A replication-competent recombinant vesicular stomatitis virus-vectored vaccine encoding a Lassa virus (LASV) glycoprotein complex, rVSVΔG-LASV-GPC, has been developed, but data on its safety and immunogenicity are limited.
25. Ten-Year Survival after Postmastectomy Chest-Wall Irradiation in Breast Cancer.
作者: Ian H Kunkler.;Nicola S Russell.;Niall Anderson.;Richard Sainsbury.;J Michael Dixon.;David Cameron.;Juliette Loncaster.;Matthew Hatton.;Helen Westenberg.;Jackie Clarke.;Heather McCarty.;Rhun Evans.;Konstantinos Geropantas.;Virginia Wolstenholme.;Abdulla Alhasso.;Pamela Woodings.;Lisa Barraclough.;Neil Bayman.;Richard Welch.;Fidelis Muturi.;Tracy McEleney.;Jacqueline Burns.;Kathleen Riddle.;Eve Macdonald.;Joanna Dunlop.;Nicole Sergenson.;Geertjan van Tienhoven.;Karen J Taylor.;John M S Bartlett.;Tammy Piper.;Galina Velikova.;Edwin Aird.;Boon Chua.;Coen Hurkmans.;Karen Venables.;Linda J Williams.;Jeremy S Thomas.;Andrew M Hanby.;Marjory Maclennan.;Susan Cleator.;Eldo T Verghese.;Yexiong Li.;Shulian Wang.;Peter Canney.; .; .
来源: N Engl J Med. 2025年393卷18期1771-1783页
The role of postmastectomy chest-wall irradiation in patients with breast cancer classified as pN1 (with involvement of one to three axillary nodes) or pN0 (pathologically node negative) with additional risk factors is uncertain.
26. A Randomized Trial of Physical Therapy for Meniscal Tear and Knee Pain.
作者: Jeffrey N Katz.;Jamie E Collins.;Leslie Bisson.;Morgan H Jones.;James J Irrgang.;Faith Selzer.;Clare E Safran-Norton.;Kurt P Spindler.;Heidi Y Yang.;Swastina Shrestha.;Kim L Bennell.;James K Sullivan.;Melissa A Kluczynski.;Kaetlyn Arant.;Maame Opare-Addo.;Jamie L Huizinga.;Zoe Zimmerman.;Derek Sople.;Peter Tonsoline.;Madhuri Kale.;William M Wind.;Antonia F Chen.;Michael Freitas.;Bryson Lesniak.;Kelly Jordan.;Elizabeth G Matzkin.;Courtney Dawson.;Lutul Farrow.;Volker Musahl.;John J Leddy.;Scott D Martin.;Elena Losina.
来源: N Engl J Med. 2025年393卷17期1694-1703页
Physical therapy is routinely recommended for knee pain attributed to a degenerative meniscal tear, but its efficacy has not been established.
27. A Pragmatic Trial of Glucocorticoids for Community-Acquired Pneumonia.
作者: Ruth K Lucinde.;Henry Gathuri.;Paul Mwaniki.;Benedict Orindi.;Edwin O Otieno.;Stella Mwakio.;Lillian Mulemi.;Lynda Isaaka.;Jimmy Shangala.;Metrine Saisi.;Elizabeth Isinde.;Irene N Oginga.;Alvin W Wachira.;Evans Manuthu.;Hazel Kariuki.;Patrick Asaava.;Jared Nyikuli.;Cyprian Wekesa.;Amos Otedo.;Hannah Bosire.;Steve B Okoth.;Winston Ongalo.;David M Mukabi.;Wilberforce Lusamba.;Beatrice Muthui.;Isaac Adembesa.;Caroline Mithi.;Mohammed Sood.;Nadia A Aliyan.;Bernard Gituma.;Matiko G Matiko.;Charles A Omondi.;Loice A Ombajo.;Nicholas Kirui.;Lucy Ochola.;Abdirahman I Abdi.;Eunice W Kagucia.;Mike English.;Mainga Hamaluba.;Isabella Ochola-Oyier.;Dorcas Kamuya.;Philip Bejon.;Edwine Barasa.;Ambrose Agweyu.;Samuel Akech.;Anthony O Etyang.
来源: N Engl J Med. 2025年393卷22期2187-2197页
Adjunctive glucocorticoids may reduce mortality among patients with severe community-acquired pneumonia (CAP) in well-resourced settings. Whether these drugs are beneficial in low-resource settings with limited diagnostic and treatment facilities is unclear.
28. Resurgence of Zoonotic Highly Pathogenic Avian Influenza A(H5N1) Virus in Cambodia.
作者: Jurre Y Siegers.;Ruopeng Xie.;Kimberly M Edwards.;Alexander M P Byrne.;Shu Hu.;Ruixuan Wang.;Sokhoun Yann.;Sarath Sin.;Songha Tok.;Kimlay Chea.;Sreyviseth Horm.;Chenthearath Rith.;Seangmai Keo.;Leakhena Pum.;Veasna Duong.;Heidi Auerswald.;Yisuong Phou.;Sonita Kol.;Andre Spiegel.;Ruth Harvey.;Sothyra Tum.;San Sorn.;Bunnary Seng.;Yi Sengdoeurn.;Darapheak Chau.;Savuth Chin.;Makara Hak.;Vanra Ieng.;Sarika Patel.;Peter Thielen.;Filip F Claes.;Nicola S Lewis.;Sovann Ly.;Erik A Karlsson.;Vijaykrishna Dhanasekaran.
来源: N Engl J Med. 2025年393卷16期1650-1652页 30. Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD.
作者: Frank G Holz.;Yannick Le Mer.;Mahiul M K Muqit.;Lars-Olof Hattenbach.;Andrea Cusumano.;Salvatore Grisanti.;Laurent Kodjikian.;Marco Andrea Pileri.;Frederic Matonti.;Eric Souied.;Boris V Stanzel.;Peter Szurman.;Michel Weber.;Karl Ulrich Bartz-Schmidt.;Nicole Eter.;Marie Noelle Delyfer.;Jean François Girmens.;Koen A van Overdam.;Armin Wolf.;Ralf Hornig.;Martina Corazzol.;Frank Brodie.;Lisa Olmos de Koo.;Daniel Palanker.;José-Alain Sahel.
来源: N Engl J Med. 2026年394卷3期232-242页
Geographic atrophy due to age-related macular degeneration (AMD) is the leading cause of irreversible blindness and affects more than 5 million persons worldwide. No therapies to restore vision in such persons currently exist. The photovoltaic retina implant microarray (PRIMA) system combines a subretinal photovoltaic implant and glasses that project near-infrared light to the implant in order to restore sight to areas of central retinal atrophy.
31. Toward Same-Day Genome Sequencing in the Critical Care Setting.
作者: Monica H Wojcik.;Katie Larkin.;Michelle Cipicchio.;Austin Doupnik.;Chen Zhao.;Cynthia Cech.;Douglas Lopez.;Jagadeeswaran Chandrasekar.;Joanne Leadbetter.;John Mannion.;Kendall Berg.;Mahdi Golkaram.;McKenna Osentowski.;Megan Freer.;Taylor Lehmann.;Won-Mean Lee.;Emily Ormbrek.;Marc J Prindle.;Melud Nabavi.;Amal Chaturvedi.;Chuck Seberino.;Daniel N Baker.;Cara Williams.;Diana Toledo.;Edyta Malolepsza.;Mark Fleharty.;Andrea Oza.;Sophie Low.;Alan H Beggs.;Casie A Genetti.;Gwendolyn Strickland.;Katherine N Anderson.;Wendy K Chung.;Heidi L Rehm.;Sean Hofherr.;Mark Kokoris.;Niall Lennon.; .
来源: N Engl J Med. 2025年393卷20期2063-2065页 33. Randomized Trial of Targeted Indoor Spraying to Prevent Aedes-Borne Diseases.
作者: Natalie E Dean.;Amy M Crisp.;Azael Che-Mendoza.;Oscar D Kirstein.;Gloria A Barrera-Fuentes.;James T Earnest.;Henry N Puerta-Guardo.;Matthew H Collins.;Norma Pavia-Ruz.;Guadalupe Ayora-Talavera.;Gabriela González-Olvera.;Anuar Medina-Barreiro.;Wilbert Bibiano-Marín.;Shirin Jabbarzadeh.;M Elizabeth Halloran.;Ira M Longini.;Audrey Lenhart.;Lance A Waller.;Fabian Correa-Morales.;Jorge Palacio-Vargas.;Hector Gomez-Dantes.;Pablo Manrique-Saide.;Gonzalo M Vazquez-Prokopec.
来源: N Engl J Med. 2025年393卷14期1387-1398页
Targeted indoor residual spraying focuses insecticide applications on common resting surfaces of Aedes aegypti mosquitoes (an arboviral disease vector) in houses, such as exposed lower sections of walls and under furniture.
35. Permethrin-Treated Baby Wraps for the Prevention of Malaria.
作者: Ross M Boyce.;Bonnie E Shook-Sa.;Ronnie Ndizeye.;Emmanuel Baguma.;Dana Giandomenico.;Caitlin A Cassidy.;Solomon Eshun.;Mark J Siedner.;Sarah G Staedke.;Moses Ntaro.;Jonathan J Juliano.;Raquel Reyes.;Edgar M Mulogo.
来源: N Engl J Med. 2025年393卷14期1399-1408页
Malaria remains a major cause of childhood death in sub-Saharan Africa. We leveraged the traditional practice of mothers carrying children on their backs in cloth wraps to assess whether treating the wraps with an insect repellent might provide a layer of protection against malaria.
36. Medical Imaging and Pediatric and Adolescent Hematologic Cancer Risk.
作者: Rebecca Smith-Bindman.;Susan A Alber.;Marilyn L Kwan.;Priscila Pequeno.;Wesley E Bolch.;Erin J A Bowles.;Robert T Greenlee.;Natasha K Stout.;Sheila Weinmann.;Lisa M Moy.;Carly Stewart.;Melanie Francisco.;Cameron Kofler.;James R Duncan.;Jonathan Ducore.;Malini Mahendra.;Jason D Pole.;Diana L Miglioretti.
来源: N Engl J Med. 2025年393卷13期1269-1278页
Assessing the risk of radiation-induced hematologic cancer from medical imaging in children and adolescents might support informed decisions on the use of imaging.
37. Introduction of Mpox Virus Clade Ib into the Republic of the Congo.
作者: Félix Koukouikila-Koussounda.;Claude Kwe Yinda.;Pembe I Mayengue.;Reiche G Elenga.;Dachel A E Boussam.;Ghislain D Indolo.;Lucette N Macosso.;Vincent J Munster.;Fabien R Niama.
来源: N Engl J Med. 2025年393卷11期1135-1137页 38. A Randomized Trial of Shunting for Idiopathic Normal-Pressure Hydrocephalus.
作者: Mark G Luciano.;Michael A Williams.;Mark G Hamilton.;Heather L Katzen.;Nickolas A Dasher.;Abhay Moghekar.;Jun Hua.;Jan Malm.;Anders Eklund.;Naomi Alpert Abel.;Ahmed M Raslan.;Benjamin D Elder.;Jesse J Savage.;Daniel L Barrow.;Kiarash Shahlaie.;Hailey Jensen.;Thomas J Zwimpfer.;Jessica Wollett.;Daniel F Hanley.;Richard Holubkov.; .
来源: N Engl J Med. 2025年393卷22期2198-2209页
Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and bladder control in older adults. The disorder is treated with shunt surgery, but the effectiveness of shunting is unclear.
39. Medications for Opioid Use Disorder in County Jails - Outcomes after Release.
作者: Peter D Friedmann.;Donna Wilson.;Thomas J Stopka.;Dana Bernson.;Ekaterina Pivovarova.;Warren Ferguson.;Randall A Hoskinson.;Rebecca E Rottapel.;Benjamin Bovell-Ammon.;Ayorkor Gaba.;Jake R Morgan.;Thomas Senst.;Edmond Hayes.;Elizabeth A Evans.; .
来源: N Engl J Med. 2025年393卷10期994-1003页
In 2019, seven county correctional facilities (jails) in Massachusetts initiated pilot programs to provide all Food and Drug Administration-approved medications for opioid use disorder (MOUD).
|