当前位置: 首页 >> 检索结果
21. Effect of Isocaloric, Time-Restricted Eating on Body Weight in Adults With Obesity : A Randomized Controlled Trial.
作者: Nisa M Maruthur.;Scott J Pilla.;Karen White.;Beiwen Wu.;May Thu Thu Maw.;Daisy Duan.;Ruth-Alma Turkson-Ocran.;Di Zhao.;Jeanne Charleston.;Courtney M Peterson.;Ryan J Dougherty.;Jennifer A Schrack.;Lawrence J Appel.;Eliseo Guallar.;Jeanne M Clark.
来源: Ann Intern Med. 2024年177卷5期549-558页
Time-restricted eating (TRE) lowers body weight in many studies. Whether TRE induces weight loss independent of reductions in calorie intake, as seen in rodent studies, is unknown.
22. Progressive Resistance Training or Neuromuscular Exercise for Hip Osteoarthritis : A Multicenter Cluster Randomized Controlled Trial.
作者: Troels Kjeldsen.;Søren T Skou.;Ulrik Dalgas.;Lisa U Tønning.;Kim G Ingwersen.;Sara Birch.;Pætur M Holm.;Thomas Frydendal.;Mette Garval.;Claus Varnum.;Bo M Bibby.;Inger Mechlenburg.
来源: Ann Intern Med. 2024年177卷5期573-582页
Exercise is recommended as first-line treatment for patients with hip osteoarthritis (OA). However, randomized controlled trials providing evidence for the optimal exercise type are lacking.
23. Clinical Outcomes With Electronic Nudges to Increase Influenza Vaccination : A Prespecified Analysis of a Nationwide, Pragmatic, Registry-Based, Randomized Implementation Trial.
作者: Niklas Dyrby Johansen.;Muthiah Vaduganathan.;Ankeet S Bhatt.;Simin Gharib Lee.;Daniel Modin.;Brian L Claggett.;Erica L Dueger.;Sandrine Samson.;Matthew M Loiacono.;Rebecca C Harris.;Lars Køber.;Scott D Solomon.;Pradeesh Sivapalan.;Jens Ulrik Stæhr Jensen.;Cyril Jean-Marie Martel.;Tyra Grove Krause.;Tor Biering-Sørensen.
来源: Ann Intern Med. 2024年177卷4期476-483页
In the NUDGE-FLU (Nationwide Utilization of Danish Government Electronic letter system for increasing inFLUenza vaccine uptake) trial, electronic letters incorporating cardiovascular (CV) gain-framing and repeated messaging increased influenza vaccination by approximately 1 percentage point.
24. Long-Term Effect of Randomization to Calcium and Vitamin D Supplementation on Health in Older Women : Postintervention Follow-up of a Randomized Clinical Trial.
作者: Cynthia A Thomson.;Aaron K Aragaki.;Ross L Prentice.;Marcia L Stefanick.;JoAnn E Manson.;Jean Wactawski-Wende.;Nelson B Watts.;Linda Van Horn.;James M Shikany.;Thomas E Rohan.;Dorothy S Lane.;Robert A Wild.;Rogelio Robles-Morales.;Aladdin H Shadyab.;Nazmus Saquib.;Jane Cauley.
来源: Ann Intern Med. 2024年177卷4期428-438页
Although calcium and vitamin D (CaD) supplementation may affect chronic disease in older women, evidence of long-term effects on health outcomes is limited.
25. A Risk Profile Using Simple Hematologic Parameters to Assess Benefits From Baricitinib in Patients Hospitalized With COVID-19: A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-2.
作者: Catharine I Paules.;Jing Wang.;Kay M Tomashek.;Tyler Bonnett.;Kanal Singh.;Vincent C Marconi.;Richard T Davey.;David C Lye.;Lori E Dodd.;Otto O Yang.;Constance A Benson.;Gregory A Deye.;Sarah B Doernberg.;Noreen A Hynes.;Robert Grossberg.;Cameron R Wolfe.;Seema U Nayak.;William R Short.;Jocelyn Voell.;Gail E Potter.;Rekha R Rapaka.
来源: Ann Intern Med. 2024年177卷3期343-352页
The ACTT risk profile, which was developed from ACTT-1 (Adaptive COVID-19 Treatment Trial-1), demonstrated that hospitalized patients with COVID-19 in the high-risk quartile (characterized by low absolute lymphocyte count [ALC], high absolute neutrophil count [ANC], and low platelet count at baseline) benefited most from treatment with the antiviral remdesivir. It is unknown which patient characteristics are associated with benefit from treatment with the immunomodulator baricitinib.
26. Surgery, Needle Fasciotomy, or Collagenase Injection for Dupuytren Contracture : A Randomized Controlled Trial.
作者: Mikko Petteri Räisänen.;Olli V Leppänen.;Janne Soikkeli.;Aleksi Reito.;Antti Malmivaara.;Rachelle Buchbinder.;Hannu Kautiainen.;Antti Kaivorinne.;Susanna Stjernberg-Salmela.;Minna Lappalainen.;Toni Luokkala.;Annele Pönkkö.;Hanna-Stiina Taskinen.;Markus Pääkkönen.;Kati Jaatinen.;Joona Juurakko.;Venla-Linnea Karjalainen.;Teemu Karjalainen.
来源: Ann Intern Med. 2024年177卷3期280-290页
Surgery, needle fasciotomy, and collagenase injection are used to treat Dupuytren contracture. The treatment decision requires balancing initial morbidity and costs of surgery against its potential long-term benefits over needle fasciotomy and collagenase.
27. Reducing Care Overuse in Older Patients Using Professional Norms and Accountability : A Cluster Randomized Controlled Trial.
作者: Stephen D Persell.;Lucia C Petito.;Ji Young Lee.;Daniella Meeker.;Jason N Doctor.;Noah J Goldstein.;Craig R Fox.;Theresa A Rowe.;Jeffrey A Linder.;Ryan Chmiel.;Yaw Amofa Peprah.;Tiffany Brown.
来源: Ann Intern Med. 2024年177卷3期324-334页
Effective strategies are needed to curtail overuse that may lead to harm.
28. Effectiveness of Existing Insomnia Therapies for Patients Undergoing Hemodialysis : A Randomized Clinical Trial.
作者: Rajnish Mehrotra.;Daniel Cukor.;Susan M McCurry.;Tessa Rue.;Maria-Eleni Roumelioti.;Patrick J Heagerty.;Mark Unruh.
来源: Ann Intern Med. 2024年177卷2期177-188页
Chronic insomnia is common in patients undergoing in-center hemodialysis, yet there is limited evidence on effective treatments for this population.
29. Endoscopic En Bloc Versus Piecemeal Resection of Large Nonpedunculated Colonic Adenomas : A Randomized Comparative Trial.
作者: Jérémie Jacques.;Marion Schaefer.;Timothée Wallenhorst.;Thomas Rösch.;Vincent Lépilliez.;Stanislas Chaussade.;Jérôme Rivory.;Romain Legros.;Jean-Baptiste Chevaux.;Sarah Leblanc.;Florian Rostain.;Maximilien Barret.;Jérémie Albouys.;Arthur Belle.;Anaïs Labrunie.;Pierre-Marie Preux.;Hugo Lepetit.;Martin Dahan.;Thierry Ponchon.;Sabrina Crépin.;Loïc Marais.;Julien Magne.;Mathieu Pioche.
来源: Ann Intern Med. 2024年177卷1期29-38页
Endoscopic resection of adenomas prevents colorectal cancer, but the optimal technique for larger lesions is controversial. Piecemeal endoscopic mucosal resection (EMR) has a low adverse event (AE) rate but a variable recurrence rate necessitating early follow-up. Endoscopic submucosal dissection (ESD) can reduce recurrence but may increase AEs.
30. Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes : A Mediation Analysis.
作者: Rajiv Agarwal.;Wanzhu Tu.;Alfredo E Farjat.;Youssef M K Farag.;Robert Toto.;Sanjay Kaul.;Robert Lawatscheck.;Katja Rohwedder.;Luis M Ruilope.;Peter Rossing.;Bertram Pitt.;Gerasimos Filippatos.;Stefan D Anker.;George L Bakris.; .
来源: Ann Intern Med. 2023年176卷12期1606-1616页
In patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), finerenone, a nonsteroidal mineralocorticoid receptor antagonist, reduces cardiovascular and kidney failure outcomes. Finerenone also lowers the urine albumin-to-creatinine ratio (UACR). Whether finerenone-induced change in UACR mediates cardiovascular and kidney failure outcomes is unknown.
31. Blood Pressure Effect of Traffic-Related Air Pollution : A Crossover Trial of In-Vehicle Filtration.
作者: Michael T Young.;Karen Jansen.;Kristen E Cosselman.;Timothy R Gould.;James A Stewart.;Timothy Larson.;Coralynn Sack.;Sverre Vedal.;Adam A Szpiro.;Joel D Kaufman.
来源: Ann Intern Med. 2023年176卷12期1586-1594页
Ambient air pollution, including traffic-related air pollution (TRAP), increases cardiovascular disease risk, possibly through vascular alterations. Limited information exists about in-vehicle TRAP exposure and vascular changes.
32. Efficacy of Acupuncture for Chronic Spontaneous Urticaria : A Randomized Controlled Trial.
作者: Hui Zheng.;Xian-Jun Xiao.;Yun-Zhou Shi.;Lei-Xiao Zhang.;Wei Cao.;Qian-Hua Zheng.;Feng Zhong.;Ping-Sheng Hao.;Ying Huang.;Ming-Ling Chen.;Wei Zhang.;Si-Yuan Zhou.;Yan-Jun Wang.;Chuan Wang.;Li Zhou.;Xiao-Qin Chen.;Zuo-Qin Yang.;Zi-Hao Zou.;Ling Zhao.;Fan-Rong Liang.;Ying Li.
来源: Ann Intern Med. 2023年176卷12期1617-1624页
The effectiveness of acupuncture for patients with chronic spontaneous urticaria (CSU), reported in a few small-scale studies, is not convincing.
33. Relationship Between Clinician Language and the Success of Behavioral Weight Loss Interventions : A Mixed-Methods Cohort Study.
作者: Charlotte Albury.;Helena Webb.;Elizabeth Stokoe.;Sue Ziebland.;Constantinos Koshiaris.;Joseph J Lee.;Paul Aveyard.
来源: Ann Intern Med. 2023年176卷11期1437-1447页
International guidelines recommend that primary care clinicians recognize obesity and offer treatment opportunistically, but there is little evidence on how clinicians can discuss weight and offer treatment in ways that are well received and effective.
34. Effects of Remote Patient Monitoring Use on Care Outcomes Among Medicare Patients With Hypertension : An Observational Study.
作者: Mitchell Tang.;Carter H Nakamoto.;Ariel D Stern.;Jose R Zubizarreta.;Felippe O Marcondes.;Lori Uscher-Pines.;Lee H Schwamm.;Ateev Mehrotra.
来源: Ann Intern Med. 2023年176卷11期1465-1475页
Remote patient monitoring (RPM) is a promising tool for improving chronic disease management. Use of RPM for hypertension monitoring is growing rapidly, raising concerns about increased spending. However, the effects of RPM are still unclear.
35. Effect of Complementary Interventions to Redesign Care on Teamwork and Quality for Hospitalized Medical Patients : A Pragmatic Controlled Trial.
作者: Kevin J O'Leary.;Julie K Johnson.;Mark V Williams.;Ronald Estrella.;Krystal Hanrahan.;Luci K Leykum.;G Randy Smith.;Jenna D Goldstein.;Jane S Kim.;Sara Thompson.;Iva Terwilliger.;Jing Song.;Jungwha Lee.;Milisa Manojlovich.
来源: Ann Intern Med. 2023年176卷11期1456-1464页
Multiple challenges impede interprofessional teamwork and the provision of high-quality care to hospitalized patients.
36. Clinical Effectiveness of Cognitively Enhanced Tai Ji Quan Training on Global Cognition and Dual-Task Performance During Walking in Older Adults With Mild Cognitive Impairment or Self-Reported Memory Concerns : A Randomized Controlled Trial.
作者: Fuzhong Li.;Peter Harmer.;Elizabeth Eckstrom.;Kathleen Fitzgerald.;Kerri Winters-Stone.
来源: Ann Intern Med. 2023年176卷11期1498-1507页
Mild cognitive impairment (MCI) negatively impacts cognition and dual-task abilities. A physical-cognitive integrated treatment approach could mitigate this risk for dementia.
37. Once-Weekly Insulin Icodec With Dosing Guide App Versus Once-Daily Basal Insulin Analogues in Insulin-Naive Type 2 Diabetes (ONWARDS 5) : A Randomized Trial.
作者: Harpreet S Bajaj.;Jens Aberle.;Melanie Davies.;Anders Meller Donatsky.;Marie Frederiksen.;Dilek G Yavuz.;Amoolya Gowda.;Ildiko Lingvay.;Bruce Bode.
来源: Ann Intern Med. 2023年176卷11期1476-1485页
Inadequate dose titration and poor adherence to basal insulin can lead to suboptimal glycemic control in persons with type 2 diabetes (T2D). Once-weekly insulin icodec (icodec) is a basal insulin analogue that is in development and is aimed at reducing treatment burden.
38. Role of Artificial Intelligence in Colonoscopy Detection of Advanced Neoplasias : A Randomized Trial.
作者: Carolina Mangas-Sanjuan.;Luisa de-Castro.;Joaquín Cubiella.;Pilar Díez-Redondo.;Adolfo Suárez.;María Pellisé.;Nereida Fernández.;Sara Zarraquiños.;Henar Núñez-Rodríguez.;Verónica Álvarez-García.;Oswaldo Ortiz.;Noelia Sala-Miquel.;Pedro Zapater.;Rodrigo Jover.; .
来源: Ann Intern Med. 2023年176卷9期1145-1152页
The role of computer-aided detection in identifying advanced colorectal neoplasia is unknown.
39. Comparative Effectiveness and Safety of Generic Versus Brand-Name Fluticasone-Salmeterol to Treat Chronic Obstructive Pulmonary Disease.
作者: William B Feldman.;Aaron S Kesselheim.;Jerry Avorn.;Massimiliano Russo.;Shirley V Wang.
来源: Ann Intern Med. 2023年176卷8期1047-1056页
In 2019, the U.S. Food and Drug Administration (FDA) approved the first generic maintenance inhaler for asthma and chronic obstructive pulmonary disease (COPD). The inhaler, Wixela Inhub (fluticasone-salmeterol; Viatris), is a substitutable version of the dry powder inhaler Advair Diskus (fluticasone-salmeterol; GlaxoSmithKline). When approving complex generic products like inhalers, the FDA applies a special "weight-of-evidence" approach. In this case, manufacturers were required to perform a randomized controlled trial in patients with asthma but not COPD, although the product received approval for both indications.
40. Impact of Social Needs Case Management on Use of Medical and Behavioral Health Services: Secondary Analysis of a Randomized Controlled Trial.
作者: Mark D Fleming.;Crystal Guo.;Margae Knox.;Daniel M Brown.;Elizabeth A Hernandez.;Amanda L Brewster.
来源: Ann Intern Med. 2023年176卷8期1139-1141页 |