当前位置: 首页 >> 检索结果
3941. First human experience with pulmonary vein isolation using a through-the-balloon circumferential ultrasound ablation system for recurrent atrial fibrillation.
作者: A Natale.;E Pisano.;J Shewchik.;D Bash.;R Fanelli.;D Potenza.;P Santarelli.;R Schweikert.;R White.;W Saliba.;L Kanagaratnam.;P Tchou.;M Lesh.
来源: Circulation. 2000年102卷16期1879-82页
Standard mapping and ablation of focal sources of atrial fibrillation are associated with very long procedure times and low efficacy. An anatomic approach to complete pulmonary vein isolation could overcome these limitations.
3942. Effects of antihypertensive therapy on glucose and insulin metabolism and on left ventricular mass: A randomized, double-blind, controlled study of 21 obese hypertensives.
Glucose and insulin levels are associated with left ventricular mass (LVM) in insulin-resistant individuals. Antihypertensive drugs have different effects on glucose and insulin metabolism (GIM) and on LVM. To evaluate whether the effects of antihypertensive therapy on LVM are associated with its effects on GIM, we compared the effects of atenolol and perindopril on these parameters in a group of insulin-resistant, obese hypertensives.
3943. Multicenter, randomized, controlled trial of 150-J biphasic shocks compared with 200- to 360-J monophasic shocks in the resuscitation of out-of-hospital cardiac arrest victims. Optimized Response to Cardiac Arrest (ORCA) Investigators.
作者: T Schneider.;P R Martens.;H Paschen.;M Kuisma.;B Wolcke.;B E Gliner.;J K Russell.;W D Weaver.;L Bossaert.;D Chamberlain.
来源: Circulation. 2000年102卷15期1780-7页
In the present study, we compared an automatic external defibrillator (AED) that delivers 150-J biphasic shocks with traditional high-energy (200- to 360-J) monophasic AEDs.
3944. Polyethylene glycol-derivatized cysteine-substitution variants of recombinant staphylokinase for single-bolus treatment of acute myocardial infarction.
作者: D Collen.;P Sinnaeve.;E Demarsin.;H Moreau.;M De Maeyer.;L Jespers.;Y Laroche.;F Van de Werf.
来源: Circulation. 2000年102卷15期1766-72页
Thrombolytic therapy of acute myocardial infarction (AMI) is evolving toward bolus administration. Derivatization of proteins with polyethylene glycol (PEG) may reduce their clearance.
3945. Survival outcomes 1 year after reperfusion therapy with either alteplase or reteplase for acute myocardial infarction: results from the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO) III Trial.
作者: E J Topol.;E M Ohman.;P W Armstrong.;R Wilcox.;A M Skene.;P Aylward.;J Simes.;A Dalby.;A Betriu.;C Bode.;H D White.;J S Hochman.;H Emanuelson.;A Vahanian.;S Sapp.;A Stebbins.;D J Moliterno.;R M Califf.
来源: Circulation. 2000年102卷15期1761-5页
New recombinant plasminogen activators have been developed to simulate the fibrinolytic action of the physiological serine protease tissue plasminogen activator (alteplase, t-PA), and have prolonged half-life features permitting bolus administration. One such activator, reteplase (r-PA), was compared with t-PA in the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-III Trial.
3946. Randomized secondary prevention trial of azithromycin in patients with coronary artery disease: primary clinical results of the ACADEMIC study.
作者: J B Muhlestein.;J L Anderson.;J F Carlquist.;K Salunkhe.;B D Horne.;R R Pearson.;T J Bunch.;A Allen.;S Trehan.;C Nielson.
来源: Circulation. 2000年102卷15期1755-60页
Chlamydia pneumoniae is associated with coronary artery disease (CAD), although its causal role is uncertain. A small preliminary study reported a >50% reduction in ischemic events by azithromycin, an antibiotic effective against C pneumoniae, in seropositive CAD patients. We tested this prospectively in a larger, randomized, double-blind study.
3947. Long-term effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis: The Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT).
作者: K K Teo.;J R Burton.;C E Buller.;S Plante.;D Catellier.;W Tymchak.;V Dzavik.;D Taylor.;S Yokoyama.;T J Montague.
来源: Circulation. 2000年102卷15期1748-54页
This long-term, multicenter, randomized, double-blind, placebo-controlled, 2 x 2 factorial, angiographic trial evaluated the effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis in normocholesterolemic patients.
3948. Effect of renal artery stenting on renal function and size in patients with atherosclerotic renovascular disease.
作者: P S Watson.;P Hadjipetrou.;S V Cox.;T C Piemonte.;A C Eisenhauer.
来源: Circulation. 2000年102卷14期1671-7页
Renal artery stenting is widely performed, but little is known about its effectiveness in preserving renal function and size in patients with renovascular disease and chronic renal insufficiency. We studied the effect of renal artery stenting on renal function and size in patients with obstructive renovascular disease and chronic renal insufficiency.
3949. Lipoprotein lipase activity is associated with severity of angina pectoris. REGRESS Study Group.
作者: J J Kastelein.;J W Jukema.;A H Zwinderman.;S Clee.;A J van Boven.;H Jansen.;T J Rabelink.;R J Peters.;K I Lie.;G Liu.;A V Bruschke.;M R Hayden.
来源: Circulation. 2000年102卷14期1629-33页
Raised triglyceride-rich lipoproteins significantly increase the risk for cardiovascular disease. Variation in the activity of the enzyme lipoprotein lipase (LPL), which is crucial in the removal of these lipoproteins, may therefore modulate this risk.
3950. 17beta-estradiol decreases endothelin-1 levels in the coronary circulation of postmenopausal women with coronary artery disease.
Estrogen reverses acetylcholine-induced coronary vasoconstriction via the possible facilitation of endothelium-derived NO. Estrogen also affects endothelium-derived constrictor factors. We therefore investigated the effects of 17beta-estradiol on coronary vasomotor responses to substance P (SP), and coronary sinus endothelin-1 and NO metabolite levels in postmenopausal women with coronary heart disease.
3951. Elevated troponin I level on admission is associated with adverse outcome of primary angioplasty in acute myocardial infarction.
作者: S Matetzky.;T Sharir.;M Domingo.;M Noc.;K Y Chyu.;S Kaul.;N Eigler.;P K Shah.;B Cercek.
来源: Circulation. 2000年102卷14期1611-6页
In patients with acute myocardial infarction (AMI) undergoing thrombolytic therapy, an elevated troponin level on admission is associated with a lower reperfusion rate and a complicated clinical course. Whether an elevated troponin level on admission similarly predicts an adverse outcome in patients undergoing primary angioplasty is currently unknown and was investigated in the present study.
3952. Therapeutic angiogenesis with recombinant fibroblast growth factor-2 improves stress and rest myocardial perfusion abnormalities in patients with severe symptomatic chronic coronary artery disease.
作者: J E Udelson.;V Dilsizian.;R J Laham.;N Chronos.;J Vansant.;M Blais.;J R Galt.;M Pike.;C Yoshizawa.;M Simons.
来源: Circulation. 2000年102卷14期1605-10页
We report the effects of the administration of recombinant fibroblast growth factor-2 (rFGF-2) protein on myocardial perfusion using single photon emission computed tomography imaging in humans with advanced coronary disease.
3953. Predictors of atrial fibrillation after conventional and beating heart coronary surgery: A prospective, randomized study.
作者: R Ascione.;M Caputo.;G Calori.;C T Lloyd.;M J Underwood.;G D Angelini.
来源: Circulation. 2000年102卷13期1530-5页
Atrial fibrillation (AF) increases the morbidity of CABG. The pathophysiology is uncertain, and its prevention remains suboptimal. This prospective, randomized study was designed to define the role of cardiopulmonary bypass (CPB) and cardioplegic arrest in the pathogenesis of this complication.
3954. Effect of amlodipine on the progression of atherosclerosis and the occurrence of clinical events. PREVENT Investigators.
作者: B Pitt.;R P Byington.;C D Furberg.;D B Hunninghake.;G B Mancini.;M E Miller.;W Riley.
来源: Circulation. 2000年102卷13期1503-10页
The results of angiographic studies have suggested that calcium channel-blocking agents may prevent new coronary lesion formation, the progression of minimal lesions, or both.
3955. The unclampable ascending aorta in coronary artery bypass patients: A surgical challenge of increasing frequency.
作者: M Gaudino.;F Glieca.;F Alessandrini.;N Luciani.;C Cellini.;C Pragliola.;G Possati.
来源: Circulation. 2000年102卷13期1497-502页
The unclampable ascending aorta (UAA) is a condition increasingly encountered during CABG procedures. We report our experience with CABG patients with UAA and place particular emphasis on the preoperative diagnosis and surgical management.
3956. Prospective, randomized, infancy-onset trial of the effects of a low-saturated-fat, low-cholesterol diet on serum lipids and lipoproteins before school age: The Special Turku Coronary Risk Factor Intervention Project (STRIP).
作者: L Rask-Nissilä.;E Jokinen.;T Rönnemaa.;J Viikari.;A Tammi.;H Niinikoski.;R Seppänen.;J Tuominen.;O Simell.
来源: Circulation. 2000年102卷13期1477-83页
We showed previously that repeated dietary counseling during the first 3 years of life reduces the concentration of serum nonfasting cholesterol. We have now extended the study to children 5 years of age and analyzed fasting blood samples, enabling LDL cholesterol calculations for the first time.
3957. Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease.
In arterial hypertension, left ventricular hypertrophy (LVH) includes myocyte hypertrophy and fibrosis, which leads to LV diastolic dysfunction and, finally, heart failure. In spontaneously hypertensive rats, myocardial fibrosis was regressed and LV diastolic function was improved by treatment with the angiotensin-converting enzyme inhibitor lisinopril. Whether this holds true for patients with hypertensive heart disease was addressed in this prospective, randomized, double-blind trial.
3958. Randomized controlled study investigating the effect of biatrial pacing in prevention of atrial fibrillation after coronary artery bypass grafting.
作者: T Levy.;G Fotopoulos.;S Walker.;S Rex.;M Octave.;V Paul.;M Amrani.
来源: Circulation. 2000年102卷12期1382-7页
Atrial fibrillation (AF) is a common problem after CABG. Prevention with prophylactic drug therapy has had limited success, therefore alternative approaches are required. This study investigated the role of biatrial pacing compared with no pacing on AF incidence after isolated first-time CABG.
3959. Canadian-American differences in the management of acute coronary syndromes in the GUSTO IIb trial: one-year follow-up of patients without ST-segment elevation. Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) II Investigators.
作者: Y Fu.;W C Chang.;D Mark.;R M Califf.;B Mackenzie.;C B Granger.;E J Topol.;M Hlatky.;P W Armstrong.
来源: Circulation. 2000年102卷12期1375-81页
Little information exists concerning practice patterns between Canada and the United States in the management of myocardial infarction (MI) patients without ST-segment elevation and unstable angina.
3960. Impact of smoking on health-related quality of life after percutaneous coronary revascularization.
作者: D A Taira.;T B Seto.;K K Ho.;H M Krumholz.;D E Cutlip.;R Berezin.;R E Kuntz.;D J Cohen.
来源: Circulation. 2000年102卷12期1369-74页
PTCA is performed primarily to improve health-related quality of life (HRQOL) in patients with symptomatic coronary artery disease. In patients undergoing PTCA, smoking has been shown to increase risks of late myocardial infarction and death. Whether smoking also affects HRQOL after PTCA is currently unknown.
|