303. Contemporary Hormonal Contraception and Risk of Venous Thromboembolism.
作者: Harman Gailan Hassan Yonis.;Lina Steinrud Mørch.;Ellen Løkkegaard.;Kristian Kragholm.;Amalie Lykkemark Møller.;Christian Torp-Pedersen.;Amani Meaidi.
来源: JAMA. 2025年333卷15期1358-1361页 304. Evaluation of a Clinical Decision Support System for Imaging Requests: A Cluster Randomized Clinical Trial.
作者: Stijntje W Dijk.;Claudia Wollny.;Joerg Barkhausen.;Olav Jansen.;Peter Mildenberger.;Moritz C Halfmann.;Jonas Stroeder.;Dimitris Rizopoulos.;M G Myriam Hunink.;Thomas Kroencke.
来源: JAMA. 2025年333卷14期1212-1221页
Given the widespread use of medical imaging, evaluating the effectiveness of interventions to improve appropriateness is crucial for optimizing health care resources and patient outcomes.
313. Simvastatin and Rifaximin in Decompensated Cirrhosis: A Randomized Clinical Trial.
作者: Elisa Pose.;César Jiménez.;Giacomo Zaccherini.;Daniela Campion.;Salvatore Piano.;Frank Erhard Uschner.;Koos de Wit.;Olivier Roux.;Kohilan Gananandan.;Wim Laleman.;Cristina Solé.;Sonia Alonso.;Berta Cuyàs.;Xavier Ariza.;Adrià Juanola.;Ann T Ma.;Laura Napoleone.;Jordi Gratacós-Ginès.;Marta Tonon.;Enrico Pompili.;Jordi Sánchez-Delgado.;Andrew S Allegretti.;Manuel Morales-Ruiz.;Marta Carol.;Martina Pérez-Guasch.;Núria Fabrellas.;Judit Pich.;Claudia Martell.;María Joyera.;Gemma Domenech.;José Ríos.;Ferrán Torres.;Miquel Serra-Burriel.;Rubén Hernáez.;Elsa Solà.;Isabel Graupera.;Hugh Watson.;Germán Soriano.;Rafael Bañares.;Rajeshwar P Mookerjee.;Claire Francoz.;Ulrich Beuers.;Jonel Trebicka.;Paolo Angeli.;Carlo Alessandria.;Paolo Caraceni.;Víctor M Vargas.;Juan G Abraldes.;Patrick S Kamath.;Pere Ginès.; .
来源: JAMA. 2025年333卷10期864-874页
There are no useful treatments to prevent the development of severe complications of liver cirrhosis. Simvastatin and rifaximin have shown beneficial effects in liver cirrhosis.
315. UV Stabilizer BTMPS in the Illicit Fentanyl Supply in 9 US Locations.
作者: Chelsea L Shover.;Morgan E Godvin.;Meghan Appley.;Elise M Pyfrom.;Fernando Montero Castrillo.;Karli Hochstatter.;Talia Nadel.;Neil Garg.;Adam Koncsol.;Joseph R Friedman.;Caitlin A Molina.;Ruby Romero.;Brendan Harshberger.;Jordan A M Gonzalez.;Jordan Spoliansky.;Sarah Laurel.;Elham Jalayer.;Juan Ruelas.;John Gonzales.;Soma Snakeoil.;Sonya Guerra.;Oscar Arellano.;Candace Winstead.;Margaret Rybak.;Joanna Champney.;Brent Waninger.;Rafael Torruella.;Edward Sisco.
来源: JAMA. 2025年333卷11期1000-1003页 318. Age and Sex Differences in Efficacy of Treatments for Type 2 Diabetes: A Network Meta-Analysis.
作者: Peter Hanlon.;Elaine Butterly.;Lili Wei.;Heather Wightman.;Saleh Ali M Almazam.;Khalid Alsallumi.;Jamie Crowther.;Ryan McChrystal.;Heidi Rennison.;Katherine Hughes.;Jim Lewsey.;Robert Lindsay.;Stuart McGurnaghan.;John Petrie.;Laurie A Tomlinson.;Sarah Wild.;Amanda Adler.;Naveed Sattar.;David M Phillippo.;Sofia Dias.;Nicky J Welton.;David A McAllister.
来源: JAMA. 2025年333卷12期1062-1073页
Sodium-glucose cotransporter 2 (SGLT2) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, and dipeptidyl peptidase 4 (DPP4) inhibitors improve hyperglycemia, and SGLT2 inhibitors and GLP-1 receptor agonists reduce the risk of major adverse cardiovascular events (MACEs) among individuals with type 2 diabetes. It is not clear whether efficacy varies by age or sex.
320. Testicular Germ Cell Tumors: A Review.
作者: Nirmish Singla.;Aditya Bagrodia.;Ezra Baraban.;Christian D Fankhauser.;Yasser M A Ged.
来源: JAMA. 2025年333卷9期793-803页
Testicular cancer is the most common solid malignancy among males aged 15 to 40 years in the US, with approximately 10 000 new cases diagnosed each year. Between 90% and 95% of testicular cancers are germ cell tumors (GCTs).
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