当前位置: 首页 >> 检索结果
301. After successful catheter ablation for AF, rivaroxaban did not reduce a composite of stroke or systemic embolism vs. aspirin at 36 mo.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text] Hematology: [Formula: see text].
302. In healthy adults, a modified RNA vs. inactivated influenza vaccine reduced laboratory-confirmed influenza-like illness at ≥14 d.
GIM/FP/GP: [Formula: see text] Infectious Disease: [Formula: see text] Public Health: [Formula: see text].
303. In adults with severe metabolic acidosis and moderate to severe AKI, IV sodium bicarbonate did not reduce mortality at 90 d.
GIM/FP/GP: [Formula: see text] Critical Care: [Formula: see text] Nephrology: [Formula: see text].
304. Stable Supportive Footwear for Self-managing Hip Osteoarthritis Pain : A Randomized Clinical Trial.
作者: Kade L Paterson.;Kim L Bennell.;Ben R Metcalf.;Fiona McManus.;Karen E Lamb.;Jesse Pardo.;Sarah Jones.;Rana S Hinman.
来源: Ann Intern Med. 2026年179卷4期469-477页
Few effective nonsurgical treatments exist for hip osteoarthritis. Footwear influences hip forces and may be a promising novel approach.
307. COVID-19 Vaccines for 2025-2026 in Adults Who Are Not Pregnant or Immunocompromised: Rapid Practice Points From the American College of Physicians.
作者: Amir Qaseem.;Adam J Obley.;Curtis S Harrod.;Timothy J Wilt.;Kate Carroll.;Linda L Humphrey.; .;Ray Haeme.;Alysa Krain.;Thejaswi Poonacha.;Sameer D Saini.;Chelsea Vigna.
来源: Ann Intern Med. 2026年179卷5期728-733页
The American College of Physicians (ACP) developed these rapid practice points addressing the effectiveness, comparative effectiveness, and harms of Omicron-adapted COVID-19 vaccines in adults (aged ≥18 years) who are not pregnant or immunocompromised.
311. Addressing Primary Care Needs in People Living With Sickle Cell Disease : A Narrative Review.
作者: Amie Patel.;Charmaine Wright.;Francis Coyne.;Rachel J Klein.;Max Jordan Nguemeni Tiako.;Alice A Kuo.;Robert M Cronin.
来源: Ann Intern Med. 2026年179卷3期394-401页
Adults with sickle cell disease (SCD) are living longer due to advances in care but face a growing burden of chronic comorbid conditions that fall within the scope of primary care. However, primary care providers often lack structured guidance because literature on managing these conditions in the context of SCD is limited. This article outlines clinical approaches to hypertension, diabetes, obesity, chronic constipation, reproductive health, cognitive impairments, depression, and anxiety in people living with SCD. The authors highlight relevant epidemiology, screening recommendations, and treatment considerations that differ from those in the general population. Primary care providers play a crucial role in delivering comprehensive and preventive care to people living with SCD. Specific management of common chronic conditions in this population is necessary to reduce morbidity and improve quality of life.
312. The Risk for Bleeding in Patients With Atrial Fibrillation From Concomitant Use of Apixaban or Rivaroxaban With Diltiazem Compared With Metoprolol.
作者: Ghadeer K Dawwas.;James D Lewis.;Yacob G Tedla.;Adam Cuker.
来源: Ann Intern Med. 2026年179卷4期515-523页
Diltiazem is a potent inhibitor of cytochrome P450 3A4 and P-glycoprotein substrates, which can affect the metabolic pathways of factor Xa inhibitors, predisposing patients with atrial fibrillation (AF) to serious bleeding complications.
314. Effectiveness, Comparative Effectiveness, and Harms of COVID-19 Vaccines in Adults Who Are Not Pregnant or Immunocompromised: A Rapid Review for the American College of Physicians.
作者: Andreea Dobrescu.;Larisa Pinte.;Amin Sharifan.;Arianna Gadinger.;Isabel Moser.;Christopher Cooper.;Gerald Gartlehner.
来源: Ann Intern Med. 2026年179卷5期673-684页
The SARS-CoV-2 Omicron variant continues to pose a global health burden.
|