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301. CYP2C19 genotype has a greater effect on adverse cardiovascular outcomes following percutaneous coronary intervention and in Asian populations treated with clopidogrel: a meta-analysis.
作者: Michael J Sorich.;Andrew Rowland.;Ross A McKinnon.;Michael D Wiese.
来源: Circ Cardiovasc Genet. 2014年7卷6期895-902页
The degree to which cytochrome P450 (CYP) 2C19 genotype influences the effectiveness of clopidogrel remains uncertain because of considerable heterogeneity in results between studies and potential publication bias. Clopidogrel indication and ethnic population have been proposed to influence the effect of CYP2C19 genotype.
302. Plasma concentrations of afamin are associated with the prevalence and development of metabolic syndrome.
作者: Florian Kronenberg.;Barbara Kollerits.;Stefan Kiechl.;Claudia Lamina.;Lyudmyla Kedenko.;Christa Meisinger.;Johann Willeit.;Cornelia Huth.;Georg Wietzorrek.;Maria E Altmann.;Barbara Thorand.;Andreas Melmer.;Doreen Dähnhardt.;Peter Santer.;Wolfgang Rathmann.;Bernhard Paulweber.;Wolfgang Koenig.;Annette Peters.;Ibrahim M Adham.;Hans Dieplinger.
来源: Circ Cardiovasc Genet. 2014年7卷6期822-9页
Afamin is a human plasma vitamin E-binding glycoprotein primarily expressed in the liver and secreted into the bloodstream. Because little is known about (patho)-physiological functions of afamin, we decided to identify phenotypes associated with afamin by investigating transgenic mice overexpressing the human afamin gene and performing large-scale human epidemiological studies.
303. Multiple associated variants increase the heritability explained for plasma lipids and coronary artery disease.
作者: Hayato Tada.;Hong-Hee Won.;Olle Melander.;Jian Yang.;Gina M Peloso.;Sekar Kathiresan.
来源: Circ Cardiovasc Genet. 2014年7卷5期583-7页
Plasma lipid levels as well as coronary artery disease (CAD) have been shown to be highly heritable with estimates ranging from 40% to 60%. However, top variants detected by large-scale genome-wide association studies explain only a fraction of the total variance in plasma lipid phenotypes and CAD.
304. Dietary linoleic acid and risk of coronary heart disease: a systematic review and meta-analysis of prospective cohort studies.
作者: Maryam S Farvid.;Ming Ding.;An Pan.;Qi Sun.;Stephanie E Chiuve.;Lyn M Steffen.;Walter C Willett.;Frank B Hu.
来源: Circulation. 2014年130卷18期1568-78页
Previous studies on intake of linoleic acid (LA), the predominant n-6 fatty acid, and coronary heart disease (CHD) risk have generated inconsistent results. We performed a systematic review and meta-analysis of prospective cohort studies to summarize the evidence regarding the relation of dietary LA intake and CHD risk.
305. More favorable response to cardiac resynchronization therapy in women than in men.
作者: Yun-Jiu Cheng.;Jing Zhang.;Wei-Jie Li.;Xiao-Xiong Lin.;Wu-Tao Zeng.;Kai Tang.;An-li Tang.;Jian-Gui He.;Qing Xu.;Mei-Yi Mei.;Dong-Dan Zheng.;Yu-Gang Dong.;Hong Ma.;Su-Hua Wu.
来源: Circ Arrhythm Electrophysiol. 2014年7卷5期807-15页
Data on sex difference in response to cardiac resynchronization therapy (CRT) remain controversial. We conducted a meta-analysis to summarize all published studies to determine whether sex-based differences in response to CRT exist.
306. Efficacy of catheter ablation for persistent atrial fibrillation: a systematic review and meta-analysis of evidence from randomized and nonrandomized controlled trials.
作者: Gareth J Wynn.;Moloy Das.;Laura J Bonnett.;Sandeep Panikker.;Tom Wong.;Dhiraj Gupta.
来源: Circ Arrhythm Electrophysiol. 2014年7卷5期841-52页
Catheter ablation (CA) is commonly performed for persistent atrial fibrillation, but few high-quality randomized controlled trials (RCTs) exist, leading to funding restrictions being proposed in several countries. We performed a random-effects meta-analysis of RCTs and non-RCTs to assess the efficacy of CA for persistent atrial fibrillation.
307. Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.
作者: Moritz F Sinner.;Nathan R Tucker.;Kathryn L Lunetta.;Kouichi Ozaki.;J Gustav Smith.;Stella Trompet.;Joshua C Bis.;Honghuang Lin.;Mina K Chung.;Jonas B Nielsen.;Steven A Lubitz.;Bouwe P Krijthe.;Jared W Magnani.;Jiangchuan Ye.;Michael H Gollob.;Tatsuhiko Tsunoda.;Martina Müller-Nurasyid.;Peter Lichtner.;Annette Peters.;Elena Dolmatova.;Michiaki Kubo.;Jonathan D Smith.;Bruce M Psaty.;Nicholas L Smith.;J Wouter Jukema.;Daniel I Chasman.;Christine M Albert.;Yusuke Ebana.;Tetsushi Furukawa.;Peter W Macfarlane.;Tamara B Harris.;Dawood Darbar.;Marcus Dörr.;Anders G Holst.;Jesper H Svendsen.;Albert Hofman.;Andre G Uitterlinden.;Vilmundur Gudnason.;Mitsuaki Isobe.;Rainer Malik.;Martin Dichgans.;Jonathan Rosand.;David R Van Wagoner.; .; .;Emelia J Benjamin.;David J Milan.;Olle Melander.;Susan R Heckbert.;Ian Ford.;Yongmei Liu.;John Barnard.;Morten S Olesen.;Bruno H C Stricker.;Toshihiro Tanaka.;Stefan Kääb.;Patrick T Ellinor.
来源: Circulation. 2014年130卷15期1225-35页
Atrial fibrillation (AF) affects >30 million individuals worldwide and is associated with an increased risk of stroke, heart failure, and death. AF is highly heritable, yet the genetic basis for the arrhythmia remains incompletely understood.
308. Low-expression variant of fatty acid-binding protein 4 favors reduced manifestations of atherosclerotic disease and increased plaque stability.
作者: Jani Saksi.;Petra Ijäs.;Mikko I Mäyränpää.;Krista Nuotio.;Pia M Isoviita.;Jarno Tuimala.;Erno Lehtonen-Smeds.;Markku Kaste.;Antti Jula.;Juha Sinisalo.;Markku S Nieminen.;Marja-Liisa Lokki.;Markus Perola.;Aki S Havulinna.;Veikko Salomaa.;Johannes Kettunen.;Matti Jauhiainen.;Petri T Kovanen.;Perttu J Lindsberg.
来源: Circ Cardiovasc Genet. 2014年7卷5期588-98页
Fatty acid-binding protein 4 (FABP4 or aP2 in mice) has been identified as a key regulator of core aspects of cardiometabolic disorders, including lipotoxic endoplasmic reticulum stress in macrophages. A functional promoter polymorphism (rs77878271) of human FABP4 gene has been described resulting in reduced FABP4 transcription.
309. Catheter ablation and antiarrhythmic drug therapy as first- or second-line therapy in the management of atrial fibrillation: systematic review and meta-analysis.
作者: Abdur Rahman Khan.;Sobia Khan.;Mujeeb A Sheikh.;Sadik Khuder.;Blair Grubb.;George V Moukarbel.
来源: Circ Arrhythm Electrophysiol. 2014年7卷5期853-60页
The optimal management of atrial fibrillation remains unclear. We performed a meta-analysis of randomized controlled trials to examine the safety and the efficacy of catheter ablation (CA) when compared with antiarrhythmic drug therapy both as first- and second-line therapy for the maintenance of sinus rhythm in atrial fibrillation.
310. Evidence-based prescribing: combining network meta-analysis with multicriteria decision analysis to choose among multiple drugs.
作者: Huseyin Naci.;Gert van Valkenhoef.;Julian P T Higgins.;Rachael Fleurence.;A E Ades.
来源: Circ Cardiovasc Qual Outcomes. 2014年7卷5期787-92页 311. Analysis of metabolic syndrome components in >15 000 african americans identifies pleiotropic variants: results from the population architecture using genomics and epidemiology study.
作者: Cara L Carty.;Samsiddhi Bhattacharjee.;Jeff Haessler.;Iona Cheng.;Lucia A Hindorff.;Vanita Aroda.;Christopher S Carlson.;Chun-Nan Hsu.;Lynne Wilkens.;Simin Liu.;Elizabeth Selvin.;Rebecca Jackson.;Kari E North.;Ulrike Peters.;James S Pankow.;Nilanjan Chatterjee.;Charles Kooperberg.
来源: Circ Cardiovasc Genet. 2014年7卷4期505-13页
Metabolic syndrome (MetS) refers to the clustering of cardiometabolic risk factors, including dyslipidemia, central adiposity, hypertension, and hyperglycemia, in individuals. Identification of pleiotropic genetic factors associated with MetS traits may shed light on key pathways or mediators underlying MetS.
312. Does cardiac resynchronization therapy benefit patients with right bundle branch block: cardiac resynchronization therapy has a role in patients with right bundle branch block.
作者: Angelo Auricchio.;Joost Lumens.;Frits W Prinzen.
来源: Circ Arrhythm Electrophysiol. 2014年7卷3期532-42页 313. Association between operator procedure volume and patient outcomes in percutaneous coronary intervention: a systematic review and meta-analysis.
作者: Jordan B Strom.;Neil J Wimmer.;Jason H Wasfy.;Kevin Kennedy.;Robert W Yeh.
来源: Circ Cardiovasc Qual Outcomes. 2014年7卷4期560-6页
The growth of centers capable of performing percutaneous coronary intervention (PCI) has outpaced population growth despite declining incidence of myocardial infarction and prevalence of coronary artery disease, potentially increasing the proportion of operators falling below minimal yearly volume standards set by professional societies.
314. Outcomes with coronary artery bypass graft surgery versus percutaneous coronary intervention for patients with diabetes mellitus: can newer generation drug-eluting stents bridge the gap?
Coronary artery bypass graft surgery (CABG) compared with percutaneous coronary intervention (PCI) reduces mortality in patients with diabetes mellitus. However, prior trials compared CABG with balloon angioplasty or older generation stents, and it is not known if the gap between CABG and PCI can be reduced by newer generation drug-eluting stents.
315. Effect of bilateral internal mammary artery grafts on long-term survival: a meta-analysis approach.
作者: Gijong Yi.;Brian Shine.;Syed M Rehman.;Douglas G Altman.;David P Taggart.
来源: Circulation. 2014年130卷7期539-45页
Although the potential survival benefit of bilateral internal mammary artery (BIMA) grafting in comparison with single internal mammary artery (SIMA) grafting has been emphasized by many investigators, the use of BIMA is still low in clinical practice in the absence of randomized trials and long-term results. In the current study, we aimed to assess if there is a long-term survival benefit of BIMA up to 10 years after coronary bypass surgery.
316. Noninducibility in postinfarction ventricular tachycardia as an end point for ventricular tachycardia ablation and its effects on outcomes: a meta-analysis.
作者: Hamid Ghanbari.;Kazim Baser.;Miki Yokokawa.;William Stevenson.;Paolo Della Bella.;Pasquale Vergara.;Thomas Deneke.;Karl-Heinz Kuck.;Hans Kottkamp.;She Fei.;Fred Morady.;Frank Bogun.
来源: Circ Arrhythm Electrophysiol. 2014年7卷4期677-83页
Although ventricular tachycardia (VT) ablation is a widely used therapy for patients with VT, the ideal end points for this procedure are not well defined. We performed a meta-analysis of the published literature to assess the predictive value of noninducibility of postinfarction VT for long-term outcomes after VT ablation.
317. Impact of sociodemographic patient characteristics on the efficacy of decision AIDS: a patient-level meta-analysis of 7 randomized trials.
作者: Megan Coylewright.;Megan Branda.;Jonathan W Inselman.;Nilay Shah.;Erik Hess.;Annie LeBlanc.;Victor M Montori.;Henry H Ting.
来源: Circ Cardiovasc Qual Outcomes. 2014年7卷3期360-7页
Decision aids (DAs) increase patient knowledge, reduce decisional conflict, and promote shared decision making (SDM). The extent to which they do so across diverse sociodemographic patient groups is unknown.
318. Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
作者: Weihua Guan.;Brian T Steffen.;Rozenn N Lemaitre.;Jason H Y Wu.;Toshiko Tanaka.;Ani Manichaikul.;Millennia Foy.;Stephen S Rich.;Lu Wang.;Jennifer A Nettleton.;Weihong Tang.;Xiangjun Gu.;Stafania Bandinelli.;Irena B King.;Barbara McKnight.;Bruce M Psaty.;David Siscovick.;Luc Djousse.;Yii-Der Ida Chen.;Luigi Ferrucci.;Myriam Fornage.;Dariush Mozafarrian.;Michael Y Tsai.;Lyn M Steffen.
来源: Circ Cardiovasc Genet. 2014年7卷3期321-331页
Omega6 (n6) polyunsaturated fatty acids (PUFAs) and their metabolites are involved in cell signaling, inflammation, clot formation, and other crucial biological processes. Genetic components, such as variants of fatty acid desaturase (FADS) genes, determine the composition of n6 PUFAs.
319. Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort.
作者: Richa Saxena.;Andrew Bjonnes.;Jennifer Prescott.;Patrick Dib.;Praveen Natt.;Jacqueline Lane.;Megan Lerner.;Jackie A Cooper.;Yuanqing Ye.;Ka Wah Li.;Cécilia G Maubaret.;Veryan Codd.;Daniel Brackett.;Lisa Mirabello.;Peter Kraft.;Colin P Dinney.;Donald Stowell.;Marvin Peyton.;Sarju Ralhan.;Gurpreet S Wander.;Narinder K Mehra.;Klelia D Salpea.;Jian Gu.;Xifeng Wu.;Massimo Mangino.;David J Hunter.;Immaculata De Vivo.;Steve E Humphries.;Nilesh J Samani.;Tim D Spector.;Sharon A Savage.;Dharambir K Sanghera.
来源: Circ Cardiovasc Genet. 2014年7卷3期287-95页
Telomere length is a heritable trait, and short telomere length has been associated with multiple chronic diseases. We investigated the relationship of relative leukocyte telomere length with cardiometabolic risk and performed the first genome-wide association study and meta-analysis to identify variants influencing relative telomere length in a population of Sikhs from South Asia.
320. Intracoronary stem cell infusion after acute myocardial infarction: a meta-analysis and update on clinical trials.
作者: Renate de Jong.;Jaco H Houtgraaf.;Sanaz Samiei.;Eric Boersma.;Henricus J Duckers.
来源: Circ Cardiovasc Interv. 2014年7卷2期156-67页
Several cell-based therapies for adjunctive treatment of acute myocardial infarction have been investigated in multiple clinical trials, but the benefits still remain controversial. This meta-analysis aims to evaluate the efficacy of bone marrow-derived mononuclear cell (BMMNC) therapy in patients with acute myocardial infarction, but also explores the effect of newer generations of stem cells.
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