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281. The Association of Epstein-Barr Virus Donor and Recipient Serostatus With Outcomes After Kidney Transplantation : A Retrospective Cohort Study.
作者: Vishnu S Potluri.;Siqi Zhang.;Douglas E Schaubel.;Salma Shaikhouni.;Emily A Blumberg.;Sunita D Nasta.;Roy D Bloom.;Massiel Cruz-Peralta.;Rajil B Mehta.;Nikhil R Lavu.;Bereket Getachew.;Srijan Tandukar.;Peter P Reese.;Chethan M Puttarajappa.
来源: Ann Intern Med. 2025年178卷2期157-166页
Prior studies indicate that 1% to 4% of Epstein-Barr virus (EBV)-seronegative recipients of EBV-seropositive donor (EBV D+/R-) kidneys develop posttransplant lymphoproliferative disorder (PTLD). However, these estimates are based on limited data that lack granularity.
282. Guidelines International Network: Principles for Use of Artificial Intelligence in the Health Guideline Enterprise.
作者: Bernardo Sousa-Pinto.;Manuel Marques-Cruz.;Ignacio Neumann.;Yuan Chi.;Artur J Nowak.;Marge Reinap.;Mariette Awad.;Monika Nothacker.;Milana Trucl.;Jan Brozek.;Pablo Alonso-Coello.;Wojtek Wiercioch.;Amir Qaseem.;Elie A Akl.;Holger J Schünemann.; .
来源: Ann Intern Med. 2025年178卷3期408-415页
Artificial intelligence (AI) has been defined by the High-Level Expert Group on AI of the European Commission as "systems that display intelligent behaviour by analysing their environment and taking actions-with some degree of autonomy-to achieve specific goals." Artificial intelligence has the potential to support guideline planning, development and adaptation, reporting, implementation, impact evaluation, certification, and appraisal of recommendations, which we will refer to as "guideline enterprise." Considering this potential, as well as the lack of guidance for the use of AI in guidelines, the Guidelines International Network (GIN) proposes a set of principles for the development and use of AI tools or processes to support the health guideline enterprise.
285. Stroke Rehabilitation: Synopsis of the 2024 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guidelines.
作者: Blessen C Eapen.;Johanna Tran.;Jennifer Ballard-Hernandez.;Andrew Buelt.;Carrie W Hoppes.;Christine Matthews.;Svetlana Pundik.;James Reston.;Zahari Tchopev.;Lisa M Wayman.;Tyler Koehn.
来源: Ann Intern Med. 2025年178卷2期249-268页
In July 2024, the U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DOD) released a joint update of their 2019 clinical practice guideline (CPG) for the management of stroke rehabilitation. This synopsis is a condensed version of the 2024 CPG, highlighting the key aspects of the guideline development process and describing the major recommendations.
289. Effectiveness of Synchronous Postdischarge Contacts on Health Care Use and Patient Satisfaction : A Systematic Review and Meta-analysis.
作者: Joel C Boggan.;Spoorthi Sankineni.;Paul A Dennis.;Dazhe Chen.;Tina Wong Sledge.;David Halpern.;Sharron Rushton.;John W Williams.;Tatyana Der.;Amir Alishahi Tabriz.;Adelaide M Gordon.;Morgan Jacobs.;Nathan A Boucher.;Maria Colandrea.;Anastasia-Stefania Alexopoulos.;Joanne Roman Jones.;Nina Leflore-Lloyd.;Sarah Cantrell.;Karen M Goldstein.;Jennifer M Gierisch.
来源: Ann Intern Med. 2025年178卷2期229-240页
Postdischarge contacts (PDCs) after hospitalization are common practice, but their effectiveness in reducing use of acute care after discharge remains unclear.
293. Predatory Journals: What Can We Do to Protect Their Prey?
作者: Christine Laine.;Dianne Babski.;Vivienne C Bachelet.;Till W Bärnighausen.;Christopher Baethge.;Kirsten Bibbins-Domingo.;Frank Frizelle.;Laragh Gollogy.;Sabine Kleinert.;Elizabeth Loder.;João Monteiro.;Eric J Rubin.;Peush Sahni.;Christina C Wee.;Jin-Hong Yoo.;Lilia Zakhama.
来源: Ann Intern Med. 2025年178卷2期294-296页 294. Incorporating Economic Evidence in Clinical Guidelines: A Framework From the Clinical Guidelines Committee of the American College of Physicians.
作者: Amir Qaseem.;Tatyana Shamliyan.;Douglas K Owens.;Jeffrey A Tice.;Carolyn J Crandall.; .;Lauri A Hicks.;Timothy J Wilt.;Ethan M Balk.;Thomas G Cooney.;J Thomas Cross.;Nick Fitterman.;Johanna Lewis.;Jennifer S Lin.;Amy Linsky.;Michael Maroto.;Matthew C Miller.;Adam J Obley.;Paul Shekelle.;Janice E Tufte.;Itziar Etxeandia-Ikobaltzeta.;Curtis S Harrod.;Jennifer Yost.;Amir Qaseem.;Tatyana Shamliyan.;Carolyn J Crandall.;Douglas K Owens.;Jeffrey A Tice.
来源: Ann Intern Med. 2025年178卷2期241-248页
In recognition of accelerating health care spending and alignment with the American College of Physicians (ACP) principles of promoting high-value care, the ACP Clinical Guidelines Committee (CGC) developed a framework to standardize its approach to identifying, appraising, and considering economic evidence in the development of ACP clinical guidelines. This article presents the CGC's process for incorporating economic evidence, which encompasses cost-effectiveness analyses, economic outcomes in randomized controlled trials, and resource utilization (intervention cost) data. Economic evidence is one component of ACP recommendations. The CGC first and foremost assesses the certainty of evidence for clinical net benefit of interventions; it then considers patient values and preferences, and only then considers economic evidence to develop recommendations.
297. Anticoagulation Among Patients Hospitalized for COVID-19 : A Systematic Review and Prospective Meta-analysis.
作者: .;Claire L Vale.;Peter J Godolphin.;David J Fisher.;Julian P T Higgins.;Alexandra McAleenan.;Francesca Spiga.;Tobias Tritschler.;Pedro Gabriel Melo de Barros E Silva.;David D Berg.;Jeffrey S Berger.;Lindsay R Berry.;Behnood Bikdeli.;Marc Blondon.;Erin A Bohula.;Marco Cattaneo.;Riccardo Colombo.;Valeria Coluccio.;Maria T DeSancho.;Michael E Farkouh.;Valentin Fuster.;Massimo Girardis.;Judith S Hochman.;Thomas P Jensen.;Vivekanand Jha.;Peter Jüni.;Ajay J Kirtane.;Patrick Lawler.;Grégoire Le Gal.;Ramon Lecumberri.;Steven R Lentz.;Renato D Lopes.;Elizabeth Lorenzi.;Marco Marietta.;Carlos Henrique Miranda.;Nuccia Morici.;Susan C Morpeth.;David A Morrow.;Zoe K McQuilten.;Nuria Muñoz-Rivas.;Matthew D Neal.;Suman Pant.;Sahil A Parikh.;Usha Perepu.;Parham Sadeghipour.;Sanjum Sethi.;Michelle Sholzberg.;Alex C Spyropoulos.;Gregg W Stone.;Azita Hajhossein Talasaz.;Steven Tong.;James Totterdell.;Balasubramanian Venkatesh.;Maddalena Alessandra Wu.;Ryan Zarychanski.;Stephane Zuily.;Julie Viry.;Jamie Rylance.;Neill K J Adhikari.;Janet V Diaz.;John C Marshall.;Jonathan A C Sterne.;Srinivas Murthy.
来源: Ann Intern Med. 2025年178卷1期59-69页
Reported results of clinical trials assessing higher-dose anticoagulation in patients hospitalized for COVID-19 have been inconsistent.
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