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2801. Discharge education improves clinical outcomes in patients with chronic heart failure.
作者: Todd M Koelling.;Monica L Johnson.;Robert J Cody.;Keith D Aaronson.
来源: Circulation. 2005年111卷2期179-85页
Although interventions combining patient education and postdischarge management have demonstrated benefits in patients with chronic heart failure, the benefit attributable to patient education alone is not known. We hypothesized that a patient discharge education program would improve clinical outcomes in patients with chronic heart failure.
2802. Cardiovascular magnetic resonance in cardiac amyloidosis.
作者: Alicia Maria Maceira.;Jayshree Joshi.;Sanjay Kumar Prasad.;James Charles Moon.;Enrica Perugini.;Idris Harding.;Mary Noelle Sheppard.;Philip Alexander Poole-Wilson.;Philip Nigel Hawkins.;Dudley John Pennell.
来源: Circulation. 2005年111卷2期186-93页
Cardiac amyloidosis can be diagnostically challenging. Cardiovascular magnetic resonance (CMR) can assess abnormal myocardial interstitium.
2803. Linear cryoablation of the left atrium versus pulmonary vein cryoisolation in patients with permanent atrial fibrillation and valvular heart disease: correlation of electroanatomic mapping and long-term clinical results.
作者: Fiorenzo Gaita.;Riccardo Riccardi.;Domenico Caponi.;Dipen Shah.;Lucia Garberoglio.;Laura Vivalda.;Alessandro Dulio.;Andrea Chiecchio.;Eric Manasse.;Roberto Gallotti.
来源: Circulation. 2005年111卷2期136-42页
The aim of this study was to clarify the role of pulmonary vein isolation (PVI) alone versus left atrial linear lesions in the treatment of permanent atrial fibrillation (AF) in patients with left atrial dilatation and valvular disease. The primary end point was to assess the persistence of sinus rhythm (SR) off antiarrhythmic drugs (AADs) at 2-year follow-up and to correlate clinical outcome with surgical results validated with electroanatomic mapping (EAM).
2804. Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries.
作者: Jeffrey J Popma.;Martin B Leon.;Jeffrey W Moses.;David R Holmes.;Nicholas Cox.;Michelle Fitzpatrick.;John Douglas.;Charles Lambert.;Michael Mooney.;Steven Yakubov.;Richard E Kuntz.; .
来源: Circulation. 2004年110卷25期3773-80页
Sirolimus-eluting stents (SESs) reduce angiographic restenosis in patients with focal, native coronary artery stenoses. This study evaluated the usefulness of SESs in complex native-vessel lesions at high risk for restenosis.
2805. Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure.
作者: Noritoshi Nagaya.;Junji Moriya.;Yoshio Yasumura.;Masaaki Uematsu.;Fumiaki Ono.;Wataru Shimizu.;Kazuyuki Ueno.;Masafumi Kitakaze.;Kunio Miyatake.;Kenji Kangawa.
来源: Circulation. 2004年110卷24期3674-9页
Ghrelin is a novel growth hormone-releasing peptide that also induces vasodilation, inhibits sympathetic nerve activity, and stimulates feeding through growth hormone-independent mechanisms. We investigated the effects of ghrelin on left ventricular (LV) function, exercise capacity, and muscle wasting in patients with chronic heart failure (CHF).
2806. Chronic kidney disease, cardiovascular risk, and response to angiotensin-converting enzyme inhibition after myocardial infarction: the Survival And Ventricular Enlargement (SAVE) study.
作者: Mariya P Tokmakova.;Hicham Skali.;Satish Kenchaiah.;Eugene Braunwald.;Jean L Rouleau.;Milton Packer.;Glenn M Chertow.;Lemuel A Moyé.;Marc A Pfeffer.;Scott D Solomon.
来源: Circulation. 2004年110卷24期3667-73页
Persons with end-stage renal disease and those with lesser degrees of chronic kidney disease (CKD) have an increased risk of death after myocardial infarction (MI) that is not fully explained by associated comorbidities. Future cardiovascular event rates and the relative response to therapy in persons with mild to moderate CKD are not well characterized.
2807. Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients.
作者: Kwang Kon Koh.;Michael J Quon.;Seung Hwan Han.;Wook-Jin Chung.;Jeong Yeal Ahn.;Yiel-Hea Seo.;Moon Ho Kang.;Tae Hoon Ahn.;In Suck Choi.;Eak Kyun Shin.
来源: Circulation. 2004年110卷24期3687-92页
Biological mechanisms underlying statin and angiotensin II type 1 receptor blocker therapies differ. Therefore, we compared vascular and metabolic responses to these therapies either alone or in combination in hypercholesterolemic, hypertensive patients.
2808. Neuropsychological outcome after percutaneous coronary intervention or coronary artery bypass grafting: results from the Stent or Surgery (SoS) Trial.
作者: Peter Währborg.;Jean E Booth.;Tim Clayton.;Fiona Nugara.;John Pepper.;William S Weintraub.;Ulrich Sigwart.;Rod H Stables.; .
来源: Circulation. 2004年110卷22期3411-7页
Coronary artery bypass surgery (CABG) has been associated with a range of neurological and neuropsychological complications from stroke to cognitive problems such as memory and problem solving disturbance. However, little is known about the impact of percutaneous coronary intervention (PCI) on neuropsychological outcome.
2809. One-year coronary bypass graft patency: a randomized comparison between off-pump and on-pump surgery angiographic results of the PRAGUE-4 trial.
作者: Petr Widimsky.;Zbynek Straka.;Petr Stros.;Karel Jirasek.;Jaroslav Dvorak.;Jan Votava.;Libor Lisa.;Tomas Budesinsky.;Miroslav Kolesar.;Tomas Vanek.;Petr Brucek.
来源: Circulation. 2004年110卷22期3418-23页
Off-pump coronary bypass surgery has become a widely used technique during recent years. However, limited data are available with regard to 1-year patency of bypass grafts implanted on the beating heart in unselected consecutive bypass surgery candidates. The aim of this study was to compare 1-year angiographic patency of bypass grafts done on the beating heart (off pump) with those done classically (on pump).
2810. Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins.
作者: Allen J Taylor.;Lance E Sullenberger.;Hyun J Lee.;Jeannie K Lee.;Karen A Grace.
来源: Circulation. 2004年110卷23期3512-7页
Niacin reduces coronary heart disease morbidity and mortality when taken either alone or in combination with statins; however, the incremental impact of adding niacin to background statin therapy is unknown.
2811. Syncope Evaluation in the Emergency Department Study (SEEDS): a multidisciplinary approach to syncope management.
作者: Win K Shen.;Wyatt W Decker.;Peter A Smars.;Deepi G Goyal.;Ann E Walker.;David O Hodge.;Jane M Trusty.;Karen M Brekke.;Arshad Jahangir.;Peter A Brady.;Thomas M Munger.;Bernard J Gersh.;Stephen C Hammill.;Robert L Frye.
来源: Circulation. 2004年110卷24期3636-45页
The primary aim and central hypothesis of the study are that a designated syncope unit in the emergency department improves diagnostic yield and reduces hospital admission for patients with syncope who are at intermediate risk for an adverse cardiovascular outcome.
2812. N-terminal pro-B-type natriuretic peptide levels for dynamic risk stratification of patients with acute coronary syndromes.
作者: Christopher Heeschen.;Christian W Hamm.;Veselin Mitrovic.;Nicte-Ha Lantelme.;Harvey D White.; .
来源: Circulation. 2004年110卷20期3206-12页
Elevated baseline levels of B-type natriuretic peptide (BNP) and the N-terminal fragments of its prohormone, N-terminal-pro-BNP (NT-proBNP), have been associated with adverse long-term outcome in patients with acute coronary syndromes, whereas the prognostic implications of serial NT-proBNP measurements have not been investigated to date.
2813. Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions.
作者: Jean-Claude Tardif.;Jean Grégoire.;Philippe L L'Allier.;Todd J Anderson.;Olivier Bertrand.;Francois Reeves.;Lawrence M Title.;Fernando Alfonso.;Erick Schampaert.;Alita Hassan.;Richard McLain.;Milton L Pressler.;Reda Ibrahim.;Jacques Lespérance.;John Blue.;Therese Heinonen.;Josep Rodés-Cabau.; .
来源: Circulation. 2004年110卷21期3372-7页
Inhibition of the acyl coenzyme A:cholesterol acyltransferase (ACAT) enzyme may prevent excess accumulation of cholesteryl esters in macrophages. The ACAT inhibitor avasimibe was shown to reduce experimental atherosclerosis. This study was designed to investigate the effects of avasimibe on human coronary atherosclerosis.
2814. Placebo-controlled, randomized clinical trial of azimilide for prevention of ventricular tachyarrhythmias in patients with an implantable cardioverter defibrillator.
作者: Paul Dorian.;Martin Borggrefe.;Hussein R Al-Khalidi.;Stefan H Hohnloser.;Jose M Brum.;Daljit S Tatla.;Johannes Brachmann.;Robert J Myerburg.;David S Cannom.;Michael van der Laan.;Michael J Holroyde.;Igor Singer.;Craig M Pratt.; .
来源: Circulation. 2004年110卷24期3646-54页
Although implanted cardioverter defibrillators (ICDs) effectively treat sustained ventricular tachyarrhythmias, up to 50% of ICD recipients eventually require concomitant antiarrhythmic drug therapy to prevent symptomatic arrhythmia recurrences and hence reduce the number of device therapies.
2815. Randomized clinical trial of abciximab in diabetic patients undergoing elective percutaneous coronary interventions after treatment with a high loading dose of clopidogrel.
作者: Julinda Mehilli.;Adnan Kastrati.;Helmut Schühlen.;Alban Dibra.;Franz Dotzer.;Nicolas von Beckerath.;Hildegard Bollwein.;Jürgen Pache.;Josef Dirschinger.;Peter P Berger.;Albert Schömig.; .
来源: Circulation. 2004年110卷24期3627-35页
Diabetic patients are at increased risk of adverse outcomes after percutaneous coronary interventions. Although subset analyses suggest particular benefit from the administration of abciximab in diabetic patients, no dedicated large randomized trials have been performed in diabetic patients undergoing percutaneous coronary intervention, and certainly not after pretreatment with a high loading dose of clopidogrel.
2816. Long-term healthcare and cost outcomes of disease management in a large, randomized, community-based population with heart failure.
作者: Autumn Dawn Galbreath.;Richard A Krasuski.;Brad Smith.;Karl C Stajduhar.;Michael D Kwan.;Robert Ellis.;Gregory L Freeman.
来源: Circulation. 2004年110卷23期3518-26页
Because of the prevalence and expense of congestive heart failure (CHF), significant efforts have been made to develop disease management (DM) programs that will improve clinical and financial outcomes. The effectiveness of such programs in a large, heterogeneous population of CHF patients remains unknown.
2817. Simvastatin prevents vascular hyporeactivity during inflammation.
作者: Johannes Pleiner.;Georg Schaller.;Friedrich Mittermayer.;Stefan Zorn.;Claudia Marsik.;Stefan Polterauer.;Stylianos Kapiotis.;Michael Wolzt.
来源: Circulation. 2004年110卷21期3349-54页
There is growing evidence that statins exert anti-inflammatory and antioxidative vascular actions that are independent of lipid lowering. We tested whether hyporeactivity to the endothelium-dependent vasodilator acetylcholine (ACh) and the vasoconstrictor norepinephrine (NE) during acute experimental inflammation could be prevented by simvastatin.
2818. Coenzyme Q10 combined with mild hypothermia after cardiac arrest: a preliminary study.
作者: Maxwell Simon Damian.;Diana Ellenberg.;Ramona Gildemeister.;Jörg Lauermann.;Gregor Simonis.;Wolfgang Sauter.;Christian Georgi.
来源: Circulation. 2004年110卷19期3011-6页
Therapeutic hypothermia can improve survival after cardiopulmonary resuscitation (CPR). Coenzyme Q10 (CoQ10) has shown a protective effect in neurodegenerative disorders. We investigated whether combining mild hypothermia with CoQ10 after out-of-hospital cardiac arrest provides additional benefit.
2819. Prevention of iatrogenic atrial tachycardia after ablation of atrial fibrillation: a prospective randomized study comparing circumferential pulmonary vein ablation with a modified approach.
作者: Carlo Pappone.;Francesco Manguso.;Gabriele Vicedomini.;Filippo Gugliotta.;Ornella Santinelli.;Amedeo Ferro.;Simone Gulletta.;Simone Sala.;Nicoleta Sora.;Gabriele Paglino.;Giuseppe Augello.;Eustachio Agricola.;Alberto Zangrillo.;Ottavio Alfieri.;Vincenzo Santinelli.
来源: Circulation. 2004年110卷19期3036-42页
Circumferential pulmonary vein ablation (CPVA) is effective in curing atrial fibrillation (AF), but new-onset left atrial tachycardia (AT) is a potential complication. We evaluated whether a modified CPVA approach including additional ablation lines on posterior wall and the mitral isthmus would reduce the incidence of AT after PV ablation.
2820. Effects of cardiac resynchronization on disease progression in patients with left ventricular systolic dysfunction, an indication for an implantable cardioverter-defibrillator, and mildly symptomatic chronic heart failure.
作者: William T Abraham.;James B Young.;Angel R León.;Stuart Adler.;Alan J Bank.;Shelley A Hall.;Randy Lieberman.;L Bing Liem.;John B O'Connell.;John S Schroeder.;Kevin R Wheelan.; .
来源: Circulation. 2004年110卷18期2864-8页
The effects of cardiac resynchronization therapy (CRT) in patients with mildly symptomatic heart failure have not been fully elucidated.
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