当前位置: 首页 >> 检索结果
2761. Increased risk of restenosis after placement of gold-coated stents: results of a randomized trial comparing gold-coated with uncoated steel stents in patients with coronary artery disease.
作者: A Kastrati.;A Schömig.;J Dirschinger.;J Mehilli.;N von Welser.;J Pache.;H Schühlen.;T Schilling.;C Schmitt.;F J Neumann.
来源: Circulation. 2000年101卷21期2478-83页
Gold is a highly biocompatible material. Experimental evidence suggests that coating the stent with a gold layer may have a beneficial influence. In this randomized trial, we assessed whether gold-coated stents were associated with a better clinical and angiographic outcome after coronary placement.
2762. Prediction of 1-year survival after thrombolysis for acute myocardial infarction in the global utilization of streptokinase and TPA for occluded coronary arteries trial.
作者: R M Califf.;K S Pieper.;K L Lee.;F Van De Werf.;R J Simes.;P W Armstrong.;E J Topol.
来源: Circulation. 2000年101卷19期2231-8页
When a patient survives thrombolysis for acute myocardial infarction, little information from large studies exists from which to estimate prognosis during follow-up visits.
2763. Safety of intracoronary gamma-radiation on uninjured reference segments during the first 6 months after treatment of in-stent restenosis: a serial intravascular ultrasound study.
作者: J M Ahmed.;G S Mintz.;R Waksman.;N J Weissman.;R Mehran.;A D Pichard.;L F Satler.;K M Kent.;M B Leon.
来源: Circulation. 2000年101卷19期2227-30页
The effects of endovascular irradiation on uninjured reference segments during the treatment of in-stent restenosis are unknown.
2764. Randomized trial of contrast media utilization in high-risk PTCA: the COURT trial.
作者: C J Davidson.;W K Laskey.;J B Hermiller.;J K Harrison.;W Matthai.;R E Vlietstra.;J A Brinker.;D J Kereiakes.;J B Muhlestein.;A Lansky.;J J Popma.;M Buchbinder.;J W Hirshfeld.
来源: Circulation. 2000年101卷18期2172-7页
Previous in vitro and in vivo studies have suggested an association between thrombus-related events and type of contrast media. Low osmolar contrast agents appear to improve the safety of diagnostic and coronary artery interventional procedures. However, no data are available on PTCA outcomes with an isosmolar contrast agent.
2765. Intracoronary gamma-radiation therapy after angioplasty inhibits recurrence in patients with in-stent restenosis.
作者: R Waksman.;R L White.;R C Chan.;B G Bass.;L Geirlach.;G S Mintz.;L F Satler.;R Mehran.;P W Serruys.;A J Lansky.;P Fitzgerald.;B Bhargava.;K M Kent.;A D Pichard.;M B Leon.
来源: Circulation. 2000年101卷18期2165-71页
Treatment of in-stent restenosis presents a critical limitation of intracoronary stent implantation. Ionizing radiation has been shown to decrease neointimal formation within stents in animal models and in initial clinical trials. We studied the effects of intracoronary gamma-radiation therapy versus placebo on the clinical and angiographic outcomes of patients with in-stent restenosis.
2766. Oral L-arginine in patients with coronary artery disease on medical management.
作者: A Blum.;L Hathaway.;R Mincemoyer.;W H Schenke.;M Kirby.;G Csako.;M A Waclawiw.;J A Panza.;R O Cannon.
来源: Circulation. 2000年101卷18期2160-4页
Vascular nitric oxide (NO) bioavailability is reduced in patients with coronary artery disease (CAD). We investigated whether oral L-arginine, the substrate for NO synthesis, improves homeostatic functions of the vascular endothelium in patients maintained on appropriate medical therapy and thus might be useful as adjunctive therapy.
2767. Beneficial effects of intracoronary adenosine as an adjunct to primary angioplasty in acute myocardial infarction.
The benefits of vessel recanalization in acute myocardial infarction (AMI) are limited by reperfusion damage. In animal models, adenosine limits reperfusion injury, reducing infarct size and improving ventricular function. The aim of this study was to evaluate the safety and feasibility of adenosine adjunct to primary PTCA in AMI.
2768. ST-Segment recovery adds to the assessment of TIMI 2 and 3 flow in predicting infarct wall motion after thrombolytic therapy.
作者: J Andrews.;I T Straznicky.;J K French.;C L Green.;A C Maas.;M Lund.;M W Krucoff.;H D White.
来源: Circulation. 2000年101卷18期2138-43页
Early resolution of ST-segment elevation (ST-segment recovery) is associated with an improved outcome after infarction. Whether this relation is present in patients with Thrombolysis In Myocardial Infarction (TIMI) grade 2 or 3 flow (ie, patent) infarct-related arteries is not known.
2769. Improvement in exercise capacity with nitric oxide inhalation in patients with precapillary pulmonary hypertension.
作者: T Hasuda.;T Satoh.;A Shimouchi.;F Sakamaki.;S Kyotani.;T Matsumoto.;Y Goto.;N Nakanishi.
来源: Circulation. 2000年101卷17期2066-70页
Patients with precapillary pulmonary hypertension (PH) exhibit a poor exercise capacity due to an impaired vasodilatory response of their pulmonary arteries. By causing the pulmonary artery to dilate, inhaled nitric oxide (NO) may allow an increase in exercise capacity in patients with PH.
2770. Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus.
作者: M Evans.;R A Anderson.;J Graham.;G R Ellis.;K Morris.;S Davies.;S K Jackson.;M J Lewis.;M P Frenneaux.;A Rees.
来源: Circulation. 2000年101卷15期1773-9页
Exaggerated postprandial lipemia (PPL) is a factor in atherogenesis, involving endothelial dysfunction and enhanced oxidative stress. We examined the effect of ciprofibrate therapy on these parameters in type 2 diabetes mellitus.
2771. Identification of patients most likely to benefit from implantable cardioverter-defibrillator therapy: the Canadian Implantable Defibrillator Study.
作者: R Sheldon.;S Connolly.;A Krahn.;R Roberts.;M Gent.;M Gardner.
来源: Circulation. 2000年101卷14期1660-4页
Patients with resuscitated ventricular tachyarrhythmias (ventricular tachycardia/ventricular fibrillation) benefit from implantable cardioverter-defibrillators (ICDs) compared with medical therapy. We hypothesized that the patients who benefit most from an ICD are those at greatest risk of death.
2772. Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan.
Structural and functional alterations of the vasculature may contribute to complications of hypertension. Because angiotensin II may be pivotal in some of these vascular abnormalities, we tested the hypothesis that the angiotensin type 1 (AT(1)) receptor antagonist losartan, in contrast to the beta-blocker atenolol, would correct resistance artery abnormalities in patients with essential hypertension.
2773. Carvedilol for prevention of restenosis after directional coronary atherectomy : final results of the European carvedilol atherectomy restenosis (EUROCARE) trial.
作者: P W Serruys.;D P Foley.;B Höfling.;J Puel.;H D Glogar.;R Seabra-Gomes.;J Goicolea.;P Coste.;W Rutsch.;H Katus.;H Bonnier.;W Wijns.;A Betriu.;U Hauf-Zachariou.;E M van Swijndregt.;R Melkert.;R Simon.
来源: Circulation. 2000年101卷13期1512-8页
In addition to its known properties as a competitive, nonselective beta and alpha-1 receptor blocker, carvedilol directly inhibits vascular myocyte migration and proliferation and exerts antioxidant effects that are considerably greater than those of vitamin E or probucol. This provides the basis for an evaluation of carvedilol for the prevention of coronary restenosis.
2774. Pharmacokinetic evaluation of triiodothyronine supplementation in children after modified Fontan procedure.
作者: R D Mainwaring.;E Capparelli.;K Schell.;M Acosta.;J C Nelson.
来源: Circulation. 2000年101卷12期1423-9页
Triiodothyronine (T(3)) supplementation may be a useful adjunct in the management of patients after cardiopulmonary bypass. Limited data are available regarding the use and pharmacokinetics of T(3) in children. The present study was performed to evaluate T(3) pharmacokinetics in a cohort of children undergoing the modified Fontan procedure.
2775. Canadian implantable defibrillator study (CIDS) : a randomized trial of the implantable cardioverter defibrillator against amiodarone.
作者: S J Connolly.;M Gent.;R S Roberts.;P Dorian.;D Roy.;R S Sheldon.;L B Mitchell.;M S Green.;G J Klein.;B O'Brien.
来源: Circulation. 2000年101卷11期1297-302页
Patients surviving ventricular fibrillation (VF) or sustained ventricular tachycardia (VT) are at a high risk of death due to a recurrence of arrhythmia. The implantable cardioverter defibrillator (ICD) terminates VT or VF, but it is not known whether this device prolongs life in these patients compared with medical therapy with amiodarone.
2776. Transthoracic cardioversion of atrial fibrillation: comparison of rectilinear biphasic versus damped sine wave monophasic shocks.
作者: S Mittal.;S Ayati.;K M Stein.;D Schwartzman.;D Cavlovich.;P J Tchou.;S M Markowitz.;D J Slotwiner.;M A Scheiner.;B B Lerman.
来源: Circulation. 2000年101卷11期1282-7页
Clinical studies have shown that biphasic shocks are more effective than monophasic shocks for ventricular defibrillation. The purpose of this study was to compare the efficacy of a rectilinear biphasic waveform with a standard damped sine wave monophasic waveform for the transthoracic cardioversion of atrial fibrillation.
2777. Inspiratory impedance during active compression-decompression cardiopulmonary resuscitation: a randomized evaluation in patients in cardiac arrest.
Blood pressure is severely reduced in patients in cardiac arrest receiving standard cardiopulmonary resuscitation (CPR). Although active compression-decompression (ACD) CPR improves acute hemodynamic parameters, arterial pressures remain suboptimal with this technique. We performed ACD CPR in patients with a new inspiratory threshold valve (ITV) to determine whether lowering intrathoracic pressures during the "relaxation" phase of ACD CPR would enhance venous blood return and overall CPR efficiency.
2778. Randomized trial comparing intravenous nitroglycerin and heparin for treatment of unstable angina secondary to restenosis after coronary artery angioplasty.
作者: S Doucet.;M Malekianpour.;P Théroux.;L Bilodeau.;G Côté.;P de Guise.;J Dupuis.;M Joyal.;G Gosselin.;J F Tanguay.;M Juneau.;F Harel.;S Nattel.;J C Tardif.;J Lespérance.
来源: Circulation. 2000年101卷9期955-61页
The treatment of unstable angina targets the specific pathophysiological thrombotic process at the site of the active culprit lesion. In unstable angina due to a restenotic lesion, smooth muscle cell proliferation and increased vasoreactivity may play a more important role than thrombus formation. Therefore, the relative benefits of nitroglycerin and heparin might differ in unstable angina associated with restenosis compared with classic unstable angina.
2779. Transcatheter closure of atrial septal defects without fluoroscopy: feasibility of a new method.
作者: P Ewert.;F Berger.;I Daehnert.;J van Wees.;M Gittermann.;H Abdul-Khaliq.;P E Lange.
来源: Circulation. 2000年101卷8期847-9页
In an effort to reduce x-ray exposure, we developed a technique for transcatheter closure of atrial septal defects under echocardiographic guidance without fluoroscopy. To assess the efficiency of this procedure for routine use, we compared our initial results with those for the conventional procedure.
2780. Prospective randomized comparison of irrigated-tip versus conventional-tip catheters for ablation of common flutter.
作者: P Jaïs.;D C Shah.;M Haïssaguerre.;M Hocini.;S Garrigue.;P Le Metayer.;J Clémenty.
来源: Circulation. 2000年101卷7期772-6页
Radiofrequency (RF) ablation of common flutter requires the creation of a complete ablation line to produce bidirectional conduction block in the cavotricuspid isthmus. An irrigated-tip ablation catheter has been shown to be effective in patients in whom conventional ablation has failed. This randomized study compares the efficacy and safety of this catheter with those of a conventional catheter for de novo flutter ablation.
|