243. After ischemic stroke in patients receiving aspirin, switching to another antithrombotic regimen does not reduce recurrence.
GIM/FP/GP:[Formula: see text] Neurology:[Formula: see text] Hematology:[Formula: see text].
244. In adults with T1D and overweight or obesity, adding GLP-1 RAs to insulin reduces weight, HbA1c levels, and insulin dose.
GIM/FP/GP:[Formula: see text] Endocrinology:[Formula: see text].
246. Functional Status of Adults at Risk of Medicaid Disenrollment Under National Work Requirements.
作者: Darshali A Vyas.;Stephen A Mein.;Archana P Tale.;Rishi K Wadhera.
来源: Ann Intern Med. 2026年179卷5期666-672页
The One Big Beautiful Bill Act (H.R.1) implemented Medicaid work requirements for beneficiaries in states participating in the Affordable Care Act, but congressional policymakers are considering extending work requirements nationally to all Medicaid enrollees. However, little is known about Medicaid-enrolled adults at risk of disenrollment.
248. Patient-Reported Outcomes in People With Type 2 Diabetes Escalating Dulaglutide or Switching From Dulaglutide to Tirzepatide.
作者: Kristina S Boye.;Palash Sharma.;Karthik K Chivukula.;Emer B Farrell.;Anita Y M Kwan.
来源: Ann Intern Med. 2026年179卷5期759-761页 249. The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID : An Adaptive Randomized Trial.
作者: Gilmar Reis.;Eduardo Augusto Dos Santos Moreira Silva.;Daniela Carla Medeiros Silva.;Lehana Thabane.;Thiago Santiago Ferreira.;Luiza Lanna França Reis.;Ana Paula Figueiredo Guimaraes Almeida.;Marcela Menezes Amaral.;Leonardo Cançado Monteiro Savassi.;Vitoria Helena de Souza Campos.;Maria Izabel Campos Simplicio.;Luciene Barra Ribeiro.;Thalyne de Souza Medeiros.;Thais Campos Siqueira.;Taynara Silva Vieira.;Nayara Drumond Rausse.;Tereza Cristina Garofolo.;Eliane Carreiro Fagundes Silva.;Ofir Harari.;Gennaro D'Urso.;Jamie I Forrest.;Jay Park.;Jean B Nachega.;Christopher Lindsell.;Jeffrey S Glenn.;Kristian Thorlund.;Mark Dybul.;Edward J Mills.; .
来源: Ann Intern Med. 2026年179卷5期621-628页
Postacute sequelae of SARS-CoV-2, or long COVID, presents a major therapeutic challenge, with fatigue being a prevalent and debilitating symptom.
252. Prevention of Recurrent Nephrolithiasis in Adults and Children : A Systematic Review.
作者: Gary N Asher.;Davis P Viprakasit.;Shannon E Aymes.;Jay B Lusk.;Sherry Ross.;Claire Baker.;Caroline Rains.;Sarah T Wright.;Leila C Kahwati.
来源: Ann Intern Med. 2026年179卷5期696-707页
Recurrent kidney stones are unpleasant and may lead to kidney damage, sepsis, or invasive procedures.
256. Timing of Pegfilgrastim Administration and Pegfilgrastim-Induced Bone Pain : A Prospective, Randomized, Phase 3 Trial.
作者: Peiyong Li.;Yitian Chen.;Yingyi Lin.;Xiaoqi Zhang.;Minyi Cheng.;Teng Zhu.;Hong-Fei Gao.;Liulu Zhang.;Jieqing Li.;Na Huang.;Yilin Chen.;Minting Liang.;Yuanqi Zhang.;Shengchao Huang.;Junqiu Zheng.;Cangui Wu.;Ciqiu Yang.;Kun Wang.
来源: Ann Intern Med. 2026年179卷5期656-665页
Pegfilgrastim-induced bone pain (PIBP) is common and lacks effective treatment.
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