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241. Comparison of community health worker-led diabetes medication decision-making support for low-income Latino and African American adults with diabetes using e-health tools versus print materials: a randomized, controlled trial.
作者: Michele Heisler.;Hwajung Choi.;Gloria Palmisano.;Rebecca Mase.;Caroline Richardson.;Angela Fagerlin.;Victor M Montori.;Michael Spencer.;Laurence C An.
来源: Ann Intern Med. 2014年161卷10 Suppl期S13-22页
Health care centers serving low-income communities have scarce resources to support medication decision making among patients with poorly controlled diabetes.
242. Multitarget therapy for induction treatment of lupus nephritis: a randomized trial.
作者: Zhihong Liu.;Haitao Zhang.;Zhangsuo Liu.;Changying Xing.;Ping Fu.;Zhaohui Ni.;Jianghua Chen.;Hongli Lin.;Fuyou Liu.;Yongcheng He.;Yani He.;Lining Miao.;Nan Chen.;Ying Li.;Yong Gu.;Wei Shi.;Weixin Hu.;Zhengzhao Liu.;Hao Bao.;Caihong Zeng.;Minlin Zhou.
来源: Ann Intern Med. 2015年162卷1期18-26页
Treatment of lupus nephritis (LN) remains challenging.
243. Re-treatment of chronic hepatitis C virus genotype 1 infection after relapse: an open-label pilot study.
作者: Anu Osinusi.;Anita Kohli.;Miriam M Marti.;Amy Nelson.;Xiaozhen Zhang.;Eric G Meissner.;Rachel Silk.;Kerry Townsend.;Phillip S Pang.;G Mani Subramanian.;John G McHutchison.;Anthony S Fauci.;Henry Masur.;Shyam Kottilil.
来源: Ann Intern Med. 2014年161卷9期634-8页
The interferon (IFN)-free regimen of sofosbuvir and ribavirin for 24 weeks was recently approved to treat chronic hepatitis C virus (HCV) genotype 1 (GT-1) infection for patients ineligible for IFN. However, sofosbuvir plus ribavirin therapy is associated with relapse in 15% to 30% of patients with HCV GT-1. Neither the mechanism of relapse nor the optimal re-treatment strategy for these patients is defined.
244. Genetic and environmental risk assessment and colorectal cancer screening in an average-risk population: a randomized trial.
作者: David S Weinberg.;Ronald E Myers.;Eileen Keenan.;Karen Ruth.;Randa Sifri.;Barry Ziring.;Eric Ross.;Sharon L Manne.
来源: Ann Intern Med. 2014年161卷8期537-45页
New methods are needed to improve health behaviors, such as adherence to colorectal cancer (CRC) screening. Personalized genetic information to guide medical decisions is increasingly available. Whether such information motivates behavioral change is unknown.
245. Support from hospital to home for elders: a randomized trial.
作者: L Elizabeth Goldman.;Urmimala Sarkar.;Eric Kessell.;David Guzman.;Michelle Schneidermann.;Edgar Pierluissi.;Barbara Walter.;Eric Vittinghoff.;Jeff Critchfield.;Margot Kushel.
来源: Ann Intern Med. 2014年161卷7期472-81页
Hospitals are implementing discharge support programs to reduce readmissions, and these programs have had mixed success.
246. Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: a randomized, controlled equivalence trial.
作者: Jeffrey L Lennox.;Raphael J Landovitz.;Heather J Ribaudo.;Ighovwerha Ofotokun.;Lumine H Na.;Catherine Godfrey.;Daniel R Kuritzkes.;Manish Sagar.;Todd T Brown.;Susan E Cohn.;Grace A McComsey.;Francesca Aweeka.;Carl J Fichtenbaum.;Rachel M Presti.;Susan L Koletar.;David W Haas.;Kristine B Patterson.;Constance A Benson.;Bryan P Baugh.;Randi Y Leavitt.;James F Rooney.;Daniel Seekins.;Judith S Currier.; .
来源: Ann Intern Med. 2014年161卷7期461-71页
Nonnucleoside reverse transcriptase inhibitor-based antiretroviral therapy is not suitable for all treatment-naive HIV-infected persons.
247. Quality-of-life outcomes with coronary artery bypass graft surgery in ischemic left ventricular dysfunction: a randomized trial.
作者: Daniel B Mark.;J David Knight.;Eric J Velazquez.;Jaroslaw Wasilewski.;Jonathan G Howlett.;Peter K Smith.;John A Spertus.;Miroslaw Rajda.;Rakesh Yadav.;Baron L Hamman.;Marcin Malinowski.;Ajay Naik.;Gena Rankin.;Tina M Harding.;Laura A Drew.;Patrice Desvigne-Nickens.;Kevin J Anstrom.
来源: Ann Intern Med. 2014年161卷6期392-9页
The STICH (Surgical Treatment for Ischemic Heart Failure) trial compared a strategy of routine coronary artery bypass grafting (CABG) with guideline-based medical therapy for patients with ischemic left ventricular dysfunction.
248. Spinal manipulation and home exercise with advice for subacute and chronic back-related leg pain: a trial with adaptive allocation.
作者: Gert Bronfort.;Maria A Hondras.;Craig A Schulz.;Roni L Evans.;Cynthia R Long.;Richard Grimm.
来源: Ann Intern Med. 2014年161卷6期381-91页
Back-related leg pain (BRLP) is often disabling and costly, and there is a paucity of research to guide its management.
249. National Lung Screening Trial findings by age: Medicare-eligible versus under-65 population.
作者: Paul F Pinsky.;David S Gierada.;William Hocking.;Edward F Patz.;Barnett S Kramer.
来源: Ann Intern Med. 2014年161卷9期627-33页
The NLST (National Lung Screening Trial) showed reduced lung cancer mortality in high-risk participants (smoking history of ≥30 pack-years) aged 55 to 74 years who were randomly assigned to screening with low-dose computed tomography (LDCT) versus those assigned to chest radiography. An advisory panel recently expressed reservations about Medicare coverage of LDCT screening because of concerns about performance in the Medicare-aged population, which accounted for only 25% of the NLST participants.
250. Effects of low-carbohydrate and low-fat diets: a randomized trial.
作者: Lydia A Bazzano.;Tian Hu.;Kristi Reynolds.;Lu Yao.;Calynn Bunol.;Yanxi Liu.;Chung-Shiuan Chen.;Michael J Klag.;Paul K Whelton.;Jiang He.
来源: Ann Intern Med. 2014年161卷5期309-18页
Low-carbohydrate diets are popular for weight loss, but their cardiovascular effects have not been well-studied, particularly in diverse populations.
251. One-year outcome of subacromial corticosteroid injection compared with manual physical therapy for the management of the unilateral shoulder impingement syndrome: a pragmatic randomized trial.
Corticosteroid injections (CSIs) and physical therapy are used to treat patients with the shoulder impingement syndrome (SIS) but have never been directly compared.
252. Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial.
作者: S Mitchell Harman.;Dennis M Black.;Frederick Naftolin.;Eliot A Brinton.;Matthew J Budoff.;Marcelle I Cedars.;Paul N Hopkins.;Rogerio A Lobo.;JoAnn E Manson.;George R Merriam.;Virginia M Miller.;Genevieve Neal-Perry.;Nanette Santoro.;Hugh S Taylor.;Eric Vittinghoff.;Mingzhu Yan.;Howard N Hodis.
来源: Ann Intern Med. 2014年161卷4期249-60页
Whether menopausal hormone therapy (MHT) protects against cardiovascular disease (CVD) remains unclear.
253. Daily oral tenofovir and emtricitabine-tenofovir preexposure prophylaxis reduces herpes simplex virus type 2 acquisition among heterosexual HIV-1-uninfected men and women: a subgroup analysis of a randomized trial.
作者: Connie Celum.;Rhoda A Morrow.;Deborah Donnell.;Ting Hong.;Craig W Hendrix.;Katherine K Thomas.;Kenneth H Fife.;Edith Nakku-Joloba.;Andrew Mujugira.;Jared M Baeten.; .
来源: Ann Intern Med. 2014年161卷1期11-9页
Daily oral preexposure prophylaxis (PrEP) using the antiretroviral tenofovir disoproxil fumarate (TDF) alone or in combination with emtricitabine (FTC-TDF) reduces the risk for HIV-1 acquisition. Tenofovir has in vitro activity against herpes simplex virus type 2 (HSV-2).
254. N-of-1 (single-patient) trials for statin-related myalgia.
作者: Tisha R Joy.;Alaa Monjed.;Guang Yong Zou.;Robert A Hegele.;Charlotte G McDonald.;Jeffrey L Mahon.
来源: Ann Intern Med. 2014年160卷5期301-10页
Statin-related myalgia is difficult to distinguish from other conditions causing myalgia and may often lead to statin discontinuation.
255. Virtual autopsy with multiphase postmortem computed tomographic angiography versus traditional medical autopsy to investigate unexpected deaths of hospitalized patients: a cohort study.
作者: Dominic Wichmann.;Axel Heinemann.;Clemens Weinberg.;Hermann Vogel.;Wilhelm Wolfgang Hoepker.;Silke Grabherr.;Klaus Pueschel.;Stefan Kluge.
来源: Ann Intern Med. 2014年160卷8期534-41页
"Virtual" autopsy by postmortem computed tomography (PMCT) can replace medical autopsy to a certain extent but has limitations for cardiovascular diseases. These limitations might be overcome by adding multiphase PMCT angiography.
256. Treatment of primary Sjögren syndrome with rituximab: a randomized trial.
作者: Valérie Devauchelle-Pensec.;Xavier Mariette.;Sandrine Jousse-Joulin.;Jean-Marie Berthelot.;Aleth Perdriger.;Xavier Puéchal.;Véronique Le Guern.;Jean Sibilia.;Jacques-Eric Gottenberg.;Laurent Chiche.;Eric Hachulla.;Pierre Yves Hatron.;Vincent Goeb.;Gilles Hayem.;Jacques Morel.;Charles Zarnitsky.;Jean Jacques Dubost.;Jacques Olivier Pers.;Emmanuel Nowak.;Alain Saraux.
来源: Ann Intern Med. 2014年160卷4期233-42页
Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by ocular and oral dryness or systemic manifestations.
257. Safety and feasibility of a diagnostic algorithm combining clinical probability, d-dimer testing, and ultrasonography for suspected upper extremity deep venous thrombosis: a prospective management study.
作者: Ankie Kleinjan.;Marcello Di Nisio.;Jan Beyer-Westendorf.;Giuseppe Camporese.;Benilde Cosmi.;Angelo Ghirarduzzi.;Pieter W Kamphuisen.;Hans-Martin Otten.;Ettore Porreca.;Anita Aggarwal.;Marianne Brodmann.;Maria Domenica Guglielmi.;Matteo Iotti.;Karin Kaasjager.;Virginia Kamvissi.;Teresa Lerede.;Peter Marschang.;Karina Meijer.;Gualtiero Palareti.;Frederick R Rickles.;Marc Righini.;Anne W S Rutjes.;Chiara Tonello.;Peter Verhamme.;Sebastian Werth.;Sanne van Wissen.;Harry R Büller.
来源: Ann Intern Med. 2014年160卷7期451-7页
Although well-established for suspected lower limb deep venous thrombosis, an algorithm combining a clinical decision score, d-dimer testing, and ultrasonography has not been evaluated for suspected upper extremity deep venous thrombosis (UEDVT).
258. Prevention of diabetes with Mediterranean diets: a subgroup analysis of a randomized trial.
作者: Jordi Salas-Salvadó.;Mònica Bulló.;Ramón Estruch.;Emilio Ros.;Maria-Isabel Covas.;Núria Ibarrola-Jurado.;Dolores Corella.;Fernando Arós.;Enrique Gómez-Gracia.;Valentina Ruiz-Gutiérrez.;Dora Romaguera.;José Lapetra.;Rosa Maria Lamuela-Raventós.;Lluís Serra-Majem.;Xavier Pintó.;Josep Basora.;Miguel Angel Muñoz.;José V Sorlí.;Miguel A Martínez-González.
来源: Ann Intern Med. 2014年160卷1期1-10页
Interventions promoting weight loss can reduce the incidence of type 2 diabetes mellitus. Whether dietary changes without calorie restriction also protect from diabetes has not been evaluated.
259. Doxycycline for stabilization of abdominal aortic aneurysms: a randomized trial.
作者: C Arnoud Meijer.;Theo Stijnen.;Martin N J M Wasser.;Jaap F Hamming.;J Hajo van Bockel.;Jan H N Lindeman.; .
来源: Ann Intern Med. 2013年159卷12期815-23页
Doxycycline inhibits formation and progression of abdominal aortic aneurysms (AAAs) in preclinical models of the disease, but it is unclear whether and how this observation translates to humans.
260. Long-term multivitamin supplementation and cognitive function in men: a randomized trial.
作者: Francine Grodstein.;Jacqueline O'Brien.;Jae Hee Kang.;Rimma Dushkes.;Nancy R Cook.;Olivia Okereke.;JoAnn E Manson.;Robert J Glynn.;Julie E Buring.;Michael Gaziano.;Howard D Sesso.
来源: Ann Intern Med. 2013年159卷12期806-14页
Despite widespread use of multivitamin supplements, their effect on cognitive health-a critical issue with aging-remains inconclusive. To date, no long-term clinical trials have studied multivitamin use and cognitive decline in older persons.
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