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221. Sofosbuvir With Velpatasvir in Treatment-Naive Noncirrhotic Patients With Genotype 1 to 6 Hepatitis C Virus Infection: A Randomized Trial.
作者: Gregory T Everson.;William J Towner.;Mitchell N Davis.;David L Wyles.;Ronald G Nahass.;Paul J Thuluvath.;Kyle Etzkorn.;Federico Hinestrosa.;Myron Tong.;Mordechai Rabinovitz.;John McNally.;Diana M Brainard.;Lingling Han.;Brian Doehle.;John G McHutchison.;Timothy Morgan.;Raymond T Chung.;Tram T Tran.
来源: Ann Intern Med. 2015年163卷11期818-26页
Effective, pangenotypic treatments for hepatitis C virus (HCV) infection are needed.
222. Alexander Technique Lessons or Acupuncture Sessions for Persons With Chronic Neck Pain: A Randomized Trial.
作者: Hugh MacPherson.;Helen Tilbrook.;Stewart Richmond.;Julia Woodman.;Kathleen Ballard.;Karl Atkin.;Martin Bland.;Janet Eldred.;Holly Essex.;Catherine Hewitt.;Ann Hopton.;Ada Keding.;Harriet Lansdown.;Steve Parrott.;David Torgerson.;Aniela Wenham.;Ian Watt.
来源: Ann Intern Med. 2015年163卷9期653-62页
Management of chronic neck pain may benefit from additional active self-care-oriented approaches.
223. Effects of Initiating Moderate Alcohol Intake on Cardiometabolic Risk in Adults With Type 2 Diabetes: A 2-Year Randomized, Controlled Trial.
作者: Yftach Gepner.;Rachel Golan.;Ilana Harman-Boehm.;Yaakov Henkin.;Dan Schwarzfuchs.;Ilan Shelef.;Ronen Durst.;Julia Kovsan.;Arkady Bolotin.;Eran Leitersdorf.;Shoshana Shpitzen.;Shai Balag.;Elad Shemesh.;Shula Witkow.;Osnat Tangi-Rosental.;Yoash Chassidim.;Idit F Liberty.;Benjamin Sarusi.;Sivan Ben-Avraham.;Anders Helander.;Uta Ceglarek.;Michael Stumvoll.;Matthias Blüher.;Joachim Thiery.;Assaf Rudich.;Meir J Stampfer.;Iris Shai.
来源: Ann Intern Med. 2015年163卷8期569-79页
Recommendations for moderate alcohol consumption remain controversial, particularly in type 2 diabetes mellitus (T2DM). Long-term randomized, controlled trials (RCTs) are lacking.
224. Visit-to-Visit Variability of Blood Pressure and Coronary Heart Disease, Stroke, Heart Failure, and Mortality: A Cohort Study.
作者: Paul Muntner.;Jeff Whittle.;Amy I Lynch.;Lisandro D Colantonio.;Lara M Simpson.;Paula T Einhorn.;Emily B Levitan.;Paul K Whelton.;William C Cushman.;Gail T Louis.;Barry R Davis.;Suzanne Oparil.
来源: Ann Intern Med. 2015年163卷5期329-38页
Variability of blood pressure (BP) across outpatient visits is frequently dismissed as random fluctuation around a patient's underlying BP.
225. Vitamin D and Calcium Attenuate Bone Loss With Antiretroviral Therapy Initiation: A Randomized Trial.
作者: Edgar Turner Overton.;Ellen S Chan.;Todd T Brown.;Pablo Tebas.;Grace A McComsey.;Kathleen M Melbourne.;Andrew Napoli.;William Royce Hardin.;Heather J Ribaudo.;Michael T Yin.
来源: Ann Intern Med. 2015年162卷12期815-24页
Antiretroviral therapy initiation for HIV-1 infection is associated with 2% to 6% loss of bone mineral density (BMD).
226. Effect of Allowing Choice of Diet on Weight Loss: A Randomized Trial.
作者: William S Yancy.;Stephanie B Mayer.;Cynthia J Coffman.;Valerie A Smith.;Ronette L Kolotkin.;Paula J Geiselman.;Megan A McVay.;Eugene Z Oddone.;Corrine I Voils.
来源: Ann Intern Med. 2015年162卷12期805-14页
Choosing a diet rather than being prescribed one could improve weight loss.
227. Coronary Computed Tomography Angiography Versus Radionuclide Myocardial Perfusion Imaging in Patients With Chest Pain Admitted to Telemetry: A Randomized Trial.
作者: Jeffrey M Levsky.;Daniel M Spevack.;Mark I Travin.;Mark A Menegus.;Paul W Huang.;Elana T Clark.;Choo-Won Kim.;Esther Hirschhorn.;Katherine D Freeman.;Jonathan N Tobin.;Linda B Haramati.
来源: Ann Intern Med. 2015年163卷3期174-83页
The role of coronary computed tomography angiography (CCTA) in the management of symptomatic patients suspected of having coronary artery disease is expanding. However, prospective intermediate-term outcomes are lacking.
228. Low-molecular-weight heparin for women with unexplained recurrent pregnancy loss: a multicenter trial with a minimization randomization scheme.
作者: Ekkehard Schleussner.;Gabriele Kamin.;Gregor Seliger.;Nina Rogenhofer.;Susanne Ebner.;Bettina Toth.;Michael Schenk.;Melanie Henes.;Michael K Bohlmann.;Thorsten Fischer.;Oana Brosteanu.;Rupert Bauersachs.;David Petroff.; .
来源: Ann Intern Med. 2015年162卷9期601-9页
A daily injection of low-molecular-weight heparin (LMWH) is often prescribed to women with unexplained recurrent pregnancy loss (RPL), although evidence suggesting a benefit is questionable.
229. Grazoprevir-Elbasvir Combination Therapy for Treatment-Naive Cirrhotic and Noncirrhotic Patients With Chronic Hepatitis C Virus Genotype 1, 4, or 6 Infection: A Randomized Trial.
作者: Stefan Zeuzem.;Reem Ghalib.;K Rajender Reddy.;Paul J Pockros.;Ziv Ben Ari.;Yue Zhao.;Deborah D Brown.;Shuyan Wan.;Mark J DiNubile.;Bach-Yen Nguyen.;Michael N Robertson.;Janice Wahl.;Eliav Barr.;Joan R Butterton.
来源: Ann Intern Med. 2015年163卷1期1-13页
Novel interferon- and ribavirin-free regimens are needed to treat hepatitis C virus (HCV) infection.
230. Surgery versus nonsurgical treatment of lumbar spinal stenosis: a randomized trial.
作者: Anthony Delitto.;Sara R Piva.;Charity G Moore.;Julie M Fritz.;Stephen R Wisniewski.;Deborah A Josbeno.;Mark Fye.;William C Welch.
来源: Ann Intern Med. 2015年162卷7期465-73页
Primary care management decisions for patients with symptomatic lumbar spinal stenosis (LSS) are challenging, and nonsurgical guidance is limited by lack of evidence.
231. Effects of exercise amount and intensity on abdominal obesity and glucose tolerance in obese adults: a randomized trial.
Exercise reduces obesity and related glucose tolerance, but whether increasing exercise intensity offers additional benefit at fixed exercise amounts is unknown.
232. Single-component versus multicomponent dietary goals for the metabolic syndrome: a randomized trial.
作者: Yunsheng Ma.;Barbara C Olendzki.;Jinsong Wang.;Gioia M Persuitte.;Wenjun Li.;Hua Fang.;Philip A Merriam.;Nicole M Wedick.;Ira S Ockene.;Annie L Culver.;Kristin L Schneider.;Gin-Fei Olendzki.;James Carmody.;Tingjian Ge.;Zhiying Zhang.;Sherry L Pagoto.
来源: Ann Intern Med. 2015年162卷4期248-57页
Few studies have compared diets to determine whether a program focused on 1 dietary change results in collateral effects on other untargeted healthy diet components.
233. Performance of Lung-RADS in the National Lung Screening Trial: a retrospective assessment.
作者: Paul F Pinsky.;David S Gierada.;William Black.;Reginald Munden.;Hrudaya Nath.;Denise Aberle.;Ella Kazerooni.
来源: Ann Intern Med. 2015年162卷7期485-91页
Lung cancer screening with low-dose computed tomography (LDCT) has been recommended, based primarily on the results of the NLST (National Lung Screening Trial). The American College of Radiology recently released Lung-RADS, a classification system for LDCT lung cancer screening.
234. A nutritional formula enriched with arginine, zinc, and antioxidants for the healing of pressure ulcers: a randomized trial.
作者: Emanuele Cereda.;Catherine Klersy.;Marcella Serioli.;Aldo Crespi.;Federico D'Andrea.; .
来源: Ann Intern Med. 2015年162卷3期167-74页
Trials on specific nutritional supplements for the treatment of pressure ulcers (PUs) have been small, inconsistent in their formulations, or unsuccessful in controlling for total supplement calorie or protein content.
235. Combination antifungal therapy for invasive aspergillosis: a randomized trial.
作者: Kieren A Marr.;Haran T Schlamm.;Raoul Herbrecht.;Scott T Rottinghaus.;Eric J Bow.;Oliver A Cornely.;Werner J Heinz.;Shyla Jagannatha.;Liang Piu Koh.;Dimitrios P Kontoyiannis.;Dong-Gun Lee.;Marcio Nucci.;Peter G Pappas.;Monica A Slavin.;Flavio Queiroz-Telles.;Dominik Selleslag.;Thomas J Walsh.;John R Wingard.;Johan A Maertens.
来源: Ann Intern Med. 2015年162卷2期81-9页
Invasive aspergillosis (IA) is associated with poor outcomes in patients with hematologic malignancies (HMs) and hematopoietic cell transplantation (HCT). Small studies suggest a role for combination antifungal therapy.
236. D-dimer testing to select patients with a first unprovoked venous thromboembolism who can stop anticoagulant therapy: a cohort study.
作者: Clive Kearon.;Frederick A Spencer.;Denis O'Keeffe.;Sameer Parpia.;Sam Schulman.;Trevor Baglin.;Scott M Stevens.;Scott Kaatz.;Kenneth A Bauer.;James D Douketis.;Steven R Lentz.;Craig M Kessler.;Stephan Moll.;Jean M Connors.;Jeffrey S Ginsberg.;Luciana Spadafora.;Jim A Julian.; .
来源: Ann Intern Med. 2015年162卷1期27-34页
Normal D-dimer levels after withdrawal of anticoagulant therapy are associated with a reduced risk for recurrence in patients with unprovoked venous thromboembolism (VTE) and may justify stopping treatment.
237. Valganciclovir for the prevention of complications of late cytomegalovirus infection after allogeneic hematopoietic cell transplantation: a randomized trial.
作者: Michael Boeckh.;W Garrett Nichols.;Roy F Chemaly.;Genovefa A Papanicolaou.;John R Wingard.;Hu Xie.;Karen L Syrjala.;Mary E D Flowers.;Terry Stevens-Ayers.;Keith R Jerome.;Wendy Leisenring.
来源: Ann Intern Med. 2015年162卷1期1-10页
Optimal prevention of late cytomegalovirus (CMV) disease is poorly defined.
238. Effectiveness of a smartphone application for weight loss compared with usual care in overweight primary care patients: a randomized, controlled trial.
作者: Brian Yoshio Laing.;Carol M Mangione.;Chi-Hong Tseng.;Mei Leng.;Ekaterina Vaisberg.;Megha Mahida.;Michelle Bholat.;Eve Glazier.;Donald E Morisky.;Douglas S Bell.
来源: Ann Intern Med. 2014年161卷10 Suppl期S5-12页
Many smartphone applications (apps) for weight loss are available, but little is known about their effectiveness.
239. Financial incentives for completion of fecal occult blood tests among veterans: a 2-stage, pragmatic, cluster, randomized, controlled trial.
作者: Jeffrey T Kullgren.;Tanisha N Dicks.;Xiaoying Fu.;Diane Richardson.;George L Tzanis.;Martin Tobi.;Steven C Marcus.
来源: Ann Intern Med. 2014年161卷10 Suppl期S35-43页
Rates of patient completion of fecal occult blood tests (FOBTs) are often low.
240. 12-month outcomes of community engagement versus technical assistance to implement depression collaborative care: a partnered, cluster, randomized, comparative effectiveness trial.
作者: Bowen Chung.;Michael Ong.;Susan L Ettner.;Felica Jones.;James Gilmore.;Michael McCreary.;Cathy Sherbourne.;Victoria Ngo.;Paul Koegel.;Lingqi Tang.;Elizabeth Dixon.;Jeanne Miranda.;Thomas R Belin.;Kenneth B Wells.
来源: Ann Intern Med. 2014年161卷10 Suppl期S23-34页
Depression collaborative care implementation using community engagement and planning (CEP) across programs improves 6-month client outcomes in minority communities, compared with technical assistance to individual programs (resources for services [RS]). However, 12-month outcomes are unknown.
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