2248. COUNTERPOINT: In the Era of Cystic Fibrosis Transmembrane Regulator Protein Modulator Therapy, Are the Treatment Goals for Adults Now Different From Those for Children With Cystic Fibrosis? No.2254. COVID-19 in Lymphangioleiomyomatosis: An International Study of Outcomes and Impact of Mechanistic Target of Rapamycin Inhibition.
作者: Bruno Guedes Baldi.;Elzbieta Radzikowska.;Vincent Cottin.;Daniel F Dilling.;Ali Ataya.;Carlos Roberto Ribeiro Carvalho.;Sergio Harari.;Matthew Koslow.;Jan C Grutters.;Yoshikazu Inoue.;Nishant Gupta.;Simon R Johnson.
来源: Chest. 2022年161卷6期1589-1593页 2255. Decision Support Tools for Low-Dose CT Lung Cancer Screening: A Scoping Review of Information Content, Format, and Presentation Methods.
作者: Mbasan Jallow.;Stefanie Bonfield.;Clara Kurtidu.;David R Baldwin.;Georgia Black.;Kate E Brain.;Michael Donnelly.;Samuel M Janes.;Grace McCutchan.;Kathryn A Robb.;Mamta Ruparel.;Sandra Van Os.;Samantha L Quaife.
来源: Chest. 2022年162卷4期930-941页
Several countries mandate informed or shared decision-making for low-dose CT (LDCT) lung cancer screening, but knowledge is limited about the type of information and presentation techniques used to support decision-making in practice. This review aimed to characterize the content, format, mode, and presentation methods of decision support tools (DSTs) for LDCT lung cancer screening. DSTs reported within peer-reviewed articles (January 2000-April 2021) were identified systematically from PubMed, PsycInfo, EMBASE, and CINAHL Plus. Inclusion criteria revolved around the development or evaluation of a resource or tool intended to support individual or shared decision-making for LDCT lung cancer screening. The data-charting and extraction framework was based on the International Patient Decision Aids Standards instrument and Template for Intervention Description and Reporting. Extracted data were organized within two categories: (1) study characteristics and context, format, and mode of DST use and (2) DST content and presentation methods. This review identified 22 DSTs in paper, video, or electronic formats across 26 articles. Most DSTs (n = 13) focused on knowledge exchange, whereas seven used interactive techniques to support values clarification (eg, Likert scales) and nine DSTs guided deliberation (eg, suggested discussion topics). The DSTs addressed similar topics, but the detail, quantification of probability, and presentation methods varied considerably. None described all the potential screening harms and results. The heterogeneity in DST design may affect the quality of decision-making, particularly for participants with lower literacy and numeracy. Evidence-based consensus guidelines for DST content and presentation methods should be developed collaboratively with screening-eligible adults.
2257. The Impact of Persistent Smoking After Surgery on Long-term Outcomes After Stage I Non-small Cell Lung Cancer Resection.
作者: Brendan T Heiden.;Daniel B Eaton.;Su-Hsin Chang.;Yan Yan.;Martin W Schoen.;Li-Shiun Chen.;Nina Smock.;Mayank R Patel.;Daniel Kreisel.;Ruben G Nava.;Bryan F Meyers.;Benjamin D Kozower.;Varun Puri.
来源: Chest. 2022年161卷6期1687-1696页
Smoking at the time of surgical treatment for lung cancer increases the risk for perioperative morbidity and mortality. The prevalence of persistent smoking in the postoperative period and its association with long-term oncologic outcomes are poorly described.
2258. Incidence of VTE in Patients With OSA: A Cohort Study.
作者: Michael V Genuardi.;Aman Rathore.;Rachel P Ogilvie.;Rebecca S DeSensi.;Priya V Borker.;Jared W Magnani.;Sanjay R Patel.
来源: Chest. 2022年161卷4期1073-1082页
Previous studies suggesting that OSA may be an independent risk factor for VTE have been limited by reliance on administrative data and lack of adjustment for clinical variables, including obesity.
2259. Co-occurrence of Physical Frailty and COPD and Association With Disability and Mortality: Singapore Longitudinal Ageing Study.
作者: Shuen Yee Lee.;Ma Shwe Zin Nyunt.;Qi Gao.;Xinyi Gwee.;Denise Qian Ling Chua.;Keng Bee Yap.;Shiou Liang Wee.;Tze Pin Ng.
来源: Chest. 2022年161卷5期1225-1238页
Physical frailty commonly is associated with COPD, and its evaluation in COPD may provide important prognostic information for risk stratification.
2260. Comparison of Guidelines for Evaluation of Suspected Pulmonary Embolism in Pregnancy: A Cost-effectiveness Analysis.
作者: John Austin McCandlish.;Chinara Feizullayeva.;Alex C Spyropoulos.;Paul P Cronin.;Jason J Naidich.;Benjamin Brenner.;Thomas McGinn.;Pina C Sanelli.;Stuart L Cohen.
来源: Chest. 2022年161卷6期1628-1641页
Pulmonary embolism (PE) remains a leading cause of maternal mortality, yet diagnosis remains challenging. International diagnostic guidelines vary significantly in their recommendations, making it difficult to determine an optimal policy for evaluation.
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