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201. Smoking and colorectal cancer: a meta-analysis.
作者: Edoardo Botteri.;Simona Iodice.;Vincenzo Bagnardi.;Sara Raimondi.;Albert B Lowenfels.;Patrick Maisonneuve.
来源: JAMA. 2008年300卷23期2765-78页
Colorectal cancer is the third most common form of cancer and the fourth most frequent cause of cancer deaths worldwide. The association between cigarette smoking and colorectal cancer has been inconsistent among studies.
202. Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: a systematic review and meta-analysis.
作者: Bethany B Barone.;Hsin-Chieh Yeh.;Claire F Snyder.;Kimberly S Peairs.;Kelly B Stein.;Rachel L Derr.;Antonio C Wolff.;Frederick L Brancati.
来源: JAMA. 2008年300卷23期2754-64页
Diabetes mellitus appears to be a risk factor for some cancers, but the effect of preexisting diabetes on all-cause mortality in newly diagnosed cancer patients is less clear.
203. Clinical equivalence of generic and brand-name drugs used in cardiovascular disease: a systematic review and meta-analysis.
作者: Aaron S Kesselheim.;Alexander S Misono.;Joy L Lee.;Margaret R Stedman.;M Alan Brookhart.;Niteesh K Choudhry.;William H Shrank.
来源: JAMA. 2008年300卷21期2514-26页
Use of generic drugs, which are bioequivalent to brand-name drugs, can help contain prescription drug spending. However, there is concern among patients and physicians that brand-name drugs may be clinically superior to generic drugs.
204. Inhaled corticosteroids in patients with stable chronic obstructive pulmonary disease: a systematic review and meta-analysis.
作者: M Bradley Drummond.;Elliott C Dasenbrook.;Marshall W Pitz.;David J Murphy.;Eddy Fan.
来源: JAMA. 2008年300卷20期2407-16页
Recent studies of inhaled corticosteroid (ICS) therapy for managing stable chronic obstructive pulmonary disease (COPD) have yielded conflicting results regarding survival and risk of adverse events.
205. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis.
作者: Shobha Rani Nalluri.;David Chu.;Roger Keresztes.;Xiaolei Zhu.;Shenhong Wu.
来源: JAMA. 2008年300卷19期2277-85页
Venous thromboembolism is one of the leading causes of morbidity and mortality in patients with cancer. Concerns have arisen regarding the risk of venous thromboembolism with the novel antiangiogenic agent bevacizumab, a recombinant humanized monoclonal antibody to vascular endothelial growth factor that is widely used in cancer treatment. Currently, the role of bevacizumab in venous thromboembolism is controversial.
206. Uninsured adults presenting to US emergency departments: assumptions vs data.
作者: Manya F Newton.;Carla C Keirns.;Rebecca Cunningham.;Rodney A Hayward.;Rachel Stanley.
来源: JAMA. 2008年300卷16期1914-24页
Emergency departments (EDs) are experiencing increased patient volumes and serve as a source of care of last resort for uninsured patients. Common assumptions about the effect of uninsured patients on the ED often drive policy solutions.
207. Circumcision status and risk of HIV and sexually transmitted infections among men who have sex with men: a meta-analysis.
作者: Gregorio A Millett.;Stephen A Flores.;Gary Marks.;J Bailey Reed.;Jeffrey H Herbst.
来源: JAMA. 2008年300卷14期1674-84页
Randomized controlled trials and meta-analyses have demonstrated that male circumcision reduces men's risk of contracting human immunodeficiency virus (HIV) infection during heterosexual intercourse. Less is known about whether male circumcision provides protection against HIV infection among men who have sex with men (MSM).
208. Effectiveness of long-term psychodynamic psychotherapy: a meta-analysis.
The place of long-term psychodynamic psychotherapy (LTPP) within psychiatry is controversial. Convincing outcome research for LTPP has been lacking.
209. Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.
Inhaled anticholinergics (ipratropium bromide or tiotropium bromide) are widely used in patients with chronic obstructive pulmonary disease (COPD) but their effect on the risk of cardiovascular outcomes is unknown.
210. Internet-based learning in the health professions: a meta-analysis.
作者: David A Cook.;Anthony J Levinson.;Sarah Garside.;Denise M Dupras.;Patricia J Erwin.;Victor M Montori.
来源: JAMA. 2008年300卷10期1181-96页
The increasing use of Internet-based learning in health professions education may be informed by a timely, comprehensive synthesis of evidence of effectiveness.
211. Benefits and risks of tight glucose control in critically ill adults: a meta-analysis.
The American Diabetes Association and Surviving Sepsis Campaign recommend tight glucose control in critically ill patients based largely on 1 trial that shows decreased mortality in a surgical intensive care unit. Because similar studies report conflicting results and tight glucose control can cause dangerous hypoglycemia, the data underlying this recommendation should be critically evaluated.
212. Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis.
作者: .;F G R Fowkes.;G D Murray.;I Butcher.;C L Heald.;R J Lee.;L E Chambless.;A R Folsom.;A T Hirsch.;M Dramaix.;G deBacker.;J-C Wautrecht.;M Kornitzer.;A B Newman.;M Cushman.;K Sutton-Tyrrell.;F G R Fowkes.;A J Lee.;J F Price.;R B d'Agostino.;J M Murabito.;P E Norman.;K Jamrozik.;J D Curb.;K H Masaki.;B L Rodríguez.;J M Dekker.;L M Bouter.;R J Heine.;G Nijpels.;C D A Stehouwer.;L Ferrucci.;M M McDermott.;H E Stoffers.;J D Hooi.;J A Knottnerus.;M Ogren.;B Hedblad.;J C Witteman.;M M B Breteler.;M G M Hunink.;A Hofman.;M H Criqui.;R D Langer.;A Fronek.;W R Hiatt.;R Hamman.;H E Resnick.;J Guralnik.;M M McDermott.
来源: JAMA. 2008年300卷2期197-208页
Prediction models to identify healthy individuals at high risk of cardiovascular disease have limited accuracy. A low ankle brachial index (ABI) is an indicator of atherosclerosis and has the potential to improve prediction.
213. Early invasive vs conservative treatment strategies in women and men with unstable angina and non-ST-segment elevation myocardial infarction: a meta-analysis.
作者: Michelle O'Donoghue.;William E Boden.;Eugene Braunwald.;Christopher P Cannon.;Tim C Clayton.;Robbert J de Winter.;Keith A A Fox.;Bo Lagerqvist.;Peter A McCullough.;Sabina A Murphy.;Rudolf Spacek.;Eva Swahn.;Lars Wallentin.;Fons Windhausen.;Marc S Sabatine.
来源: JAMA. 2008年300卷1期71-80页
Although an invasive strategy is frequently used in patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS), data from some trials suggest that this strategy may not benefit women.
214. Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: a meta-analysis.
作者: Charles Natanson.;Steven J Kern.;Peter Lurie.;Steven M Banks.;Sidney M Wolfe.
来源: JAMA. 2008年299卷19期2304-12页
Hemoglobin-based blood substitutes (HBBSs) are infusible oxygen-carrying liquids that have long shelf lives, have no need for refrigeration or cross-matching, and are ideal for treating hemorrhagic shock in remote settings. Some trials of HBBSs during the last decade have reported increased risks without clinical benefit.
215. Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis.
More than a quarter of the human population is likely infected with soil-transmitted helminths (Ascaris lumbricoides, hookworm, and Trichuris trichiura) in highly endemic areas. Preventive chemotherapy is the mainstay of control, but only 4 drugs are available: albendazole, mebendazole, levamisole, and pyrantel pamoate.
216. Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia.
作者: Charles L Bennett.;Samuel M Silver.;Benjamin Djulbegovic.;Athena T Samaras.;C Anthony Blau.;Kara J Gleason.;Sara E Barnato.;Kathleen M Elverman.;D Mark Courtney.;June M McKoy.;Beatrice J Edwards.;Cara C Tigue.;Dennis W Raisch.;Paul R Yarnold.;David A Dorr.;Timothy M Kuzel.;Martin S Tallman.;Steven M Trifilio.;Dennis P West.;Stephen Y Lai.;Michael Henke.
来源: JAMA. 2008年299卷8期914-24页
The erythropoiesis-stimulating agents (ESAs) erythropoietin and darbepoetin are licensed to treat chemotherapy-associated anemia in patients with nonmyeloid malignancies. Although systematic overviews of trials have identified venous thromboembolism (VTE) risks, none have identified mortality risks with ESAs.
217. Active smoking and the risk of type 2 diabetes: a systematic review and meta-analysis.
作者: Carole Willi.;Patrick Bodenmann.;William A Ghali.;Peter D Faris.;Jacques Cornuz.
来源: JAMA. 2007年298卷22期2654-64页
Observational studies have suggested an association between active smoking and the incidence of type 2 diabetes.
218. Association of apolipoprotein E genotypes with lipid levels and coronary risk.
作者: Anna M Bennet.;Emanuele Di Angelantonio.;Zheng Ye.;Frances Wensley.;Anette Dahlin.;Anders Ahlbom.;Bernard Keavney.;Rory Collins.;Björn Wiman.;Ulf de Faire.;John Danesh.
来源: JAMA. 2007年298卷11期1300-11页
Previous reviews of associations of apolipoprotein E (apoE) genotype and coronary disease have been dominated by smaller studies that are liable to biases.
219. Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis.
Recent reports of serious adverse events with rosiglitazone use have raised questions about whether the evidence of harm justifies its use for treatment of type 2 diabetes.
220. Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials.
作者: A Michael Lincoff.;Kathy Wolski.;Stephen J Nicholls.;Steven E Nissen.
来源: JAMA. 2007年298卷10期1180-8页
Pioglitazone is widely used for glycemic control in patients with type 2 diabetes mellitus, but evidence is mixed regarding the influence of medications of this class on cardiovascular outcomes.
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