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201. Long-Term Impact of Helicobacter pylori Eradication Therapy on Gastric Cancer Incidence and Mortality in Healthy Infected Individuals: A Meta-Analysis Beyond 10 Years of Follow-Up.202. The diagnostic utility of endocytoscopy for the detection of gastric cancer: a systematic review and meta-analysis.
作者: Andrew Canakis.;Shivanand Bomman.;Benjamin Twery.;Nevin Varghese.;Byung Ji.;Justin Canakis.;Eric M Goldberg.
来源: Minerva Gastroenterol (Torino). 2024年70卷2期225-230页
Endocytoscopy (ECS) is an evolving technology that utilizes ultra-high power magnification for real time cellular imaging without the need for physical biopsy. Its application for gastric cancer (GC) detection is not well evaluated at the current time, but there is potential that ECS can make a real time histopathological diagnosis to differentiate neoplastic from benign lesions. We aimed to investigate the diagnostic utility of ECS for GC detection.
203. Deep Submucosal Invasion Is Not an Independent Risk Factor for Lymph Node Metastasis in T1 Colorectal Cancer: A Meta-Analysis.
作者: Liselotte W Zwager.;Barbara A J Bastiaansen.;Nahid S M Montazeri.;Roel Hompes.;Valeria Barresi.;Katsuro Ichimasa.;Hiroshi Kawachi.;Isidro Machado.;Tadahiko Masaki.;Weiqi Sheng.;Shinji Tanaka.;Kazutomo Togashi.;Chihiro Yasue.;Paul Fockens.;Leon M G Moons.;Evelien Dekker.
来源: Gastroenterology. 2022年163卷1期174-189页
Deep submucosal invasion (DSI) is considered a key risk factor for lymph node metastasis (LNM) and important criterion to recommend surgery in T1 colorectal cancer. However, metastatic risk for DSI is shown to be low in the absence of other histologic risk factors. This meta-analysis determines the independent risk of DSI for LNM.
204. The role of faecal calprotectin in diagnosis and staging of colorectal neoplasia: a systematic review and meta-analysis.
作者: Fiona A Ross.;James H Park.;David Mansouri.;Emilie Combet.;Paul G Horgan.;Donald C McMillan.;Campbell S D Roxburgh.
来源: BMC Gastroenterol. 2022年22卷1期176页
The presence of inflammation is a key hallmark of cancer and, plays an important role in disease progression and survival in colorectal cancer (CRC). Calprotectin detected in the faeces is a sensitive measure of colonic inflammation. The role of FC as a diagnostic test that may categorise patients by risk of neoplasia is poorly defined. This systematic review and meta-analysis aims to characterise the relationship between elevations of FC and colorectal neoplasia.
205. Sleeve gastrectomy versus Roux-en-Y Gastric Bypass for remission of type 2 diabetes mellitus at 1, 3 and 5 years: a systematic review and meta-analysis.
作者: Kaneez Fatima.;Sabeeh K Farooqui.;Izma Ajaz.;Shaikh T Ali.;Nida Hashmi.;Sara Nadeem.;Sameed A Ghazi.;Shahzeb H Kaleem.;Fatima S Bozdar.;Mushk Noorani.
来源: Minerva Gastroenterol (Torino). 2022年68卷4期450-458页
Sleeve gastrectomy (SG) and Roux-en-Y Gastric Bypass (RYGB) are the two procedures used in the management of patient with obesity and type 2 diabetes mellitus (T2DM); however, it is still unclear which of the two is more efficient in the remission of type-2 diabetes mellitus.
206. Lack of relationship between PROX1 expression and clinicopathological parameters and prognosis in gastric cancer patients: a meta-analysis and TCGA analysis.
The relationship between PROX1 expression and clinicopathological characteristics and prognosis in patients with gastric cancer (GC) remain controversial. The aim of this study is to determine the clinicopathological and prognostic significance of PROX1 expression in patients with GC.
207. Characterization of short-chain fatty acids in patients with ulcerative colitis: a meta-analysis.
作者: Hao-Ming Xu.;Hai-Lan Zhao.;Gong-Jing Guo.;Jing Xu.;You-Lian Zhou.;Hong-Li Huang.;Yu-Qiang Nie.
来源: BMC Gastroenterol. 2022年22卷1期117页
Studies investigating the changes in short-chain fatty acids (SCFAs) in patients with ulcerative colitis (UC) have yielded inconsistent results. We performed a meta-analysis of studies that investigated the alterations in different SCFAs among UC patients to assess their role in the development of UC.
208. Are gastrointestinal symptoms associated with higher risk of Mortality in COVID-19 patients? A systematic review and meta-analysis.
Gastrointestinal symptoms have been reported in patients with COVID-19. Several clinical investigations suggested that gastrointestinal symptoms were associated with disease severity of COVID-19. However, the relevance of gastrointestinal symptoms and mortality of COVID-19 remains largely unknown. We aim to investigate the relationship between gastrointestinal symptoms and COVID-19 mortality.
209. Systematic review and meta-analysis: the advantage of endoscopic Mayo score 0 over 1 in patients with ulcerative colitis.
作者: Angelo Viscido.;Marco Valvano.;Gianpiero Stefanelli.;Annalisa Capannolo.;Chiara Castellini.;Eugenia Onori.;Antonio Ciccone.;Filippo Vernia.;Giovanni Latella.
来源: BMC Gastroenterol. 2022年22卷1期92页
Mucosal healing (MH) evaluated by endoscopy is a novel target of therapy in UC as it is associated with improved long-term outcomes. It is defined based on the Mayo endoscopic score (MES), but it is still to define whether a value of MES 0 or 1 should be the target. The purpose of this paper is to present the results of a systematic review with meta-analysis which compares long-term outcomes of patients in steroid-free clinical remission with MES 0 with those with MES 1.
210. A Systematic Review and Meta-analysis of Dietary Interventions Modulating Gut Microbiota and Cardiometabolic Diseases-Striving for New Standards in Microbiome Studies.
作者: Ilias Attaye.;Moritz V Warmbrunn.;Aureline N A F Boot.;Suze C van der Wolk.;Barbara A Hutten.;Joost G Daams.;Hilde Herrema.;Max Nieuwdorp.
来源: Gastroenterology. 2022年162卷7期1911-1932页
Cardiometabolic diseases (CMDs) have shared properties and causes. Insulin resistance is a risk factor and characteristic of CMDs and has been suggested to be modulated by plasma metabolites derived from gut microbiota (GM). Because diet is among the most important modulators of GM, we performed a systematic review of the literature to assess whether CMDs can be modulated via dietary interventions targeting the GM.
211. Toll-Like Receptor 1 Locus Re-examined in a Genome-Wide Association Study Update on Anti-Helicobacter pylori IgG Titers.
作者: Suk Yee Lam.;Michiel C Mommersteeg.;Bingting Yu.;Linda Broer.;Manon C W Spaander.;Fabian Frost.;Stefan Weiss.;Henry Völzke.;Markus M Lerch.;Ben Schöttker.;Yan Zhang.;Hannah Stocker.;Hermann Brenner.;Daniel Levy.;Shih-Jen Hwang.;Alexis C Wood.;Stephen S Rich.;Jerome I Rotter.;Kent D Taylor.;Russell P Tracy.;Edmond K Kabagambe.;Marcis Leja.;Janis Klovins.;Raitis Peculis.;Dace Rudzite.;Liene Nikitina-Zake.;Girts Skenders.;Vita Rovite.;André Uitterlinden.;Ernst J Kuipers.;Gwenny M Fuhler.;Georg Homuth.;Maikel P Peppelenbosch.
来源: Gastroenterology. 2022年162卷6期1705-1715页
A genome-wide significant association between anti-Helicobacter pylori (H pylori) IgG titers and Toll-like receptor (TLR1/6/10) locus on 4p14 was demonstrated for individuals of European ancestry, but not uniformly replicated. We re-investigated this association in an updated genome-wide association study (GWAS) meta-analysis for populations with low gastric cancer incidence, address potential causes of cohort heterogeneity, and explore functional implications of genetic variation at the TLR1/6/10 locus.
212. A case for improved assessment of gut permeability: a meta-analysis quantifying the lactulose:mannitol ratio in coeliac and Crohn's disease.
作者: Jonathan Gan.;Scarlet Nazarian.;Julian Teare.;Ara Darzi.;Hutan Ashrafian.;Alex J Thompson.
来源: BMC Gastroenterol. 2022年22卷1期16页
A widely used method in assessing small bowel permeability is the lactulose:mannitol test, where the lactulose:mannitol ratio (LMR) is measured. However, there is discrepancy in how the test is conducted and in the values of LMR obtained across studies. This meta-analysis aims to determine LMR in healthy subjects, coeliac and Crohn's disease.
213. Clinical and Endoscopic Characteristics Associated With Post-Endoscopy Upper Gastrointestinal Cancers: A Systematic Review and Meta-analysis.
作者: Leo Alexandre.;Theo Tsilegeridis-Legeris.;Stephen Lam.
来源: Gastroenterology. 2022年162卷4期1123-1135页
Ten percent of patients with an upper gastrointestinal cancer will have received an esophagogastroduodenoscopy (EGD) within 3 years before diagnosis, termed post-endoscopy upper gastrointestinal cancers (PEUGIC). We aimed to determine the characteristics of PEUGIC, and compare these with detected cancers.
214. Association of HSD17B13 rs72613567: TA allelic variant with liver disease: review and meta-analysis.
作者: Shan Tang.;Jing Zhang.;Ting-Ting Mei.;Wen-Yan Zhang.;Su-Jun Zheng.;Hai-Bin Yu.
来源: BMC Gastroenterol. 2021年21卷1期490页
To assess the association of HSD17B13 rs72613567:TA allelic variant with liver disease, we performed the current review and meta-analysis.
215. Helicobacter pylori infection is associated with reduced risk of Barrett's esophagus: a meta-analysis and systematic review.
Helicobacter pylori (Hp) is a class I carcinogen in gastric carcinogenesis, but its role in Barrett's esophagus (BE) is unknown. Therefore, we aimed to explore the possible relationship.
216. Late-Stage Pancreatic Cancer Detected During High-Risk Individual Surveillance: A Systematic Review and Meta-Analysis.
作者: Ankit Chhoda.;Ziga Vodusek.;Kapil Wattamwar.;Eric Mukherjee.;Craig Gunderson.;Alyssa Grimshaw.;Anup Sharma.;Nita Ahuja.;Fay Kastrinos.;James J Farrell.
来源: Gastroenterology. 2022年162卷3期786-798页
Identification and resection of successful targets, that is, T1 N0M0 pancreatic ductal adenocarcinoma (PDAC) and high-grade precursors during surveillance of high-risk individuals (HRIs) confers improved survival. Late-stage PDACs refer to T2-4 N0M0 and nodal or distant metastatic PDAC stages diagnosed during the follow-up phase of HRI surveillance. This study aimed to quantify late-stage PDACs during HRI surveillance and identify associated clinicoradiologic factors.
217. Clinicopathological significance of HSP70 expression in gastric cancer: a systematic review and meta-analysis.
Heat shock protein 70 (HSP70) has been associated with the clinicopathological characteristics and prognosis of many cancers types, implying that it is a potential cancer biomarker. However, no consensus has been reached regarding its clinicopathological and prognostic significance in patients with gastric cancer. To address this gap, we performed a systematic review and meta-analysis.
218. Efficacy of Biologic Drugs in Short-Duration Versus Long-Duration Inflammatory Bowel Disease: A Systematic Review and an Individual-Patient Data Meta-Analysis of Randomized Controlled Trials.
作者: Shomron Ben-Horin.;Lena Novack.;Ren Mao.;Jing Guo.;Yue Zhao.;Ruslan Sergienko.;Jian Zhang.;Taku Kobayashi.;Toshifumi Hibi.;Yehuda Chowers.;Laurent Peyrin-Biroulet.;Jean Frederic Colombel.;Gilaad G Kaplan.;Min-Hu Chen.
来源: Gastroenterology. 2022年162卷2期482-494页
Starting biologic treatment early in the course of inflammatory bowel disease (IBD) may be associated with higher efficacy, especially in Crohn's disease (CD).
219. Serologic Response to Coronavirus Disease 2019 (COVID-19) Vaccination in Patients With Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-analysis.
Patients with immune-mediated inflammatory diseases (IMIDs) have an increased risk of coronavirus disease 2019 (COVID-19), primarily attributed to the use of immunosuppressive drugs such as glucocorticoids, which may attenuate the response to vaccines. This meta-analysis assessed the serologic response to COVID-19 vaccination in patients with IMIDs.
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